Showing 14,981 - 15,000 results of 16,778 for search 'Itzy~', query time: 1.40s Refine Results
  1. 14981
  2. 14982
  3. 14983

    Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

    Published 2024-02-01
    “…The machine learning analysis of the TIME had better accuracy than the human count evaluations (AUC of human count, CD8-positive lymphocyte: 0.681, FoxP3-positive lymphocytes: 0.626, PD-L1 score: 0.567).Conclusions The spatial analysis of the TIME using machine learning predicted the immunotherapy efficacy in patients with SCLC, thus supporting its role as an immunotherapy biomarker.…”
    Get full text
    Article
  4. 14984
  5. 14985
  6. 14986
  7. 14987
  8. 14988
  9. 14989

    A concept of natural genome reconstruction. Part 2. Effect of extracellular double-stranded DNA fragments on hematopoietic stem cells by V. S. Ruzanova, S. G. Oshikhmina, A. S. Proskurina, G. S. Ritter, S. S. Kirikovich, E. V. Levites, Y. R. Efremov, T. V. Karamysheva, M. I. Meschaninova, A. L. Mamaev, O. S. Taranov, A. S. Bogachev, S. V. Sidorov, S. D. Nikonov, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, E. V. Dolgova, S. S. Bogachev

    Published 2025-01-01
    “…Extracellular fragments delivered to hematopoietic stem cells initiate division of the original hematopoietic stem cell in such a way that one of the daughter cells becomes committed to terminal differentiation, and the second retains its low-differentiated status. After treatment of bone marrow cells with hDNAgr, the number of CD34+ cells in the colonies increases to 3 % (humans as the model organism). …”
    Get full text
    Article
  10. 14990
  11. 14991

    Assessing Mental Illness Referral Request Acceptance: A Nationwide E-Referral Data From Saudi Arabia by Alharbi AA, Aljerian NA, Alghamdi HA, Binhotan MS, Alsultan AK, Arafat MS, Aldhabib A, Aloqayli AI, Alwahbi EB, Horner RD

    Published 2025-02-01
    “…The system’s selective acceptance patterns reflect its capability to prioritize care based on clinical urgency and resource availability. …”
    Get full text
    Article
  12. 14992
  13. 14993
  14. 14994
  15. 14995

    Eye Collateral Channel Characteristic Analysis and Identification Model Construction of Mild Cognitive Impairment by WU Tiecheng, CAO Lei, YIN Lianhua, HE Youze, LIU Zhizhen, YANG Minguang, XU Ying, WU Jinsong

    Published 2024-02-01
    “…By comparing the model performance, the optimal model was selected to achieve early clinical recognition.ResultsThe important eye collateral channel characteristics of the MCI group were red dots, dull brown spots, dull yellow fog diffusion, mounds, red blood veins, and tortuous blood veins (<italic>P</italic>&lt;0.05), their distribution frequency was higher than that of the normal cognition group (<italic>P</italic>&lt;0.05), but the distribution frequency of dull pink spots was lower than that of the normal cognition group (<italic>P</italic>&lt;0.05). …”
    Get full text
    Article
  16. 14996
  17. 14997

    High-Resolution Mapping of Concentrated Solar Power Site Suitability in Gharda&#x00EF;a, Algeria: A GIS-Based Fuzzy Logic and Multi-Criteria Decision Analysis by Abdelfetah Belaid, Mawloud Guermoui, Abdelkader Riche, Toufik Arrif, Hamdani Maamar, Cherier Mohamed Kamel, Abdelaziz Rabehi, Mohamad Mahmoud Al Rahhal

    Published 2025-01-01
    “…Algeria primarily relies on fossil fuels to meet its growing electricity demand, significantly contributing to climate change and the depletion of non-renewable resources. …”
    Get full text
    Article
  18. 14998

    Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity by Yaqin Yuan, Wenqing Ning, Junjie Chen, Jiquan Li, Tianqi Xue, Cuihong An, Lingling Mao, Guangzhi Zhang, Shizhong Zhou, Jiabo Ding, Xiaowen Yang, Jianqiang Ye

    Published 2025-01-01
    “…., and the identified STPK or its pathway can serve as a potential target for new drug development against rifampicin-resistant Brucella spp.IMPORTANCENew rifampicin resistance gene in Brucella melitensis is identified via bioinformatics predictions and a whole-genome transposon mutant library, new mechanisms of rifampicin resistance in B. melitensis, and new function of serine/threonine protein kinase gene and its interaction proteins.…”
    Get full text
    Article
  19. 14999

    Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

    Published 2025-02-01
    “…Introduction Methamphetamine use disorder is a global public health concern with no approved pharmacotherapies for its treatment. One recent randomised controlled trial conducted in the USA examined a combination of bupropion and naltrexone not readily available globally. …”
    Get full text
    Article
  20. 15000