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    Tuina alleviates the muscle atrophy induced by sciatic nerve injury in rats through regulation of PI3K/Akt signaling by Yingqi Zhang, Hanyu Zhang, Jiayue Liu, Jiawei Sun, Yue Xu, Narentuya Shi, Hongzheng Zhang, Jiawang Yan, Jinping Chen, Hourong Wang, Tianyuan Yu

    Published 2024-12-01
    “…Furthermore, we observed that tuina differentially regulated the levels of IGF-1, FoxO and p-FoxO, and the protein expression of p-Phosphoinositide 3-kinase (p-PI3K), p-AKT, and vascular endothelial growth factor in the anterior tibial muscle and soleus muscles. Conclusion Tuina could effectively inhibit skeletal muscle atrophy via the microcirculation pathway in a rat model of SNI by regulating the expression of IGF-1 and FoxO. …”
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    Adenosine A2A receptor activation is necessary to gate the TrkB-dependent intramuscular nerve sprouting during muscle reinnervation after a nerve crush by Michael Di Palma, Davide Lattanzi, Patrizia Ambrogini, Stefano Sartini

    Published 2025-01-01
    “…The reinnervation process of the soleus muscle was examined in both sedentary and trained animals ten days following a nerve crush injury. …”
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