Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users by Jessica A. Wright, Linda Huang, Basant E. Katamesh, Siddhant Yadav, Abhinav Singla, Ann Vincent

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FLI and FIB-4 in diagnosing metabolic dysfunction-associated steatotic liver disease in primary care: High prevalence and risk of significant disease by Mário Reis Álvares-da-Silva, Márcia da Silva Vargas, Soheyla Mohd Souza Rabie, Gabriella Jonko, Patricia Gabriela Riedel, Larisse Longo, Marcelo Rodrigues Gonçalves, Vivian Cristine Luft, Dvora Joveleviths

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Effect of epileptiform discharges and hippocampal volume on cognitive dysfunction following clipping of ruptured aneurysms in the anterior circulation by Kunitoshi Otsuka, Shigeki Sunaga, Hiroyuki Jimbo, Yoshinori Suzuki, Michihiro Kohno

“…Epileptiform discharges were assessed using the spike index (SI).ResultsWe included 60 patients (23 men, 37 women; median age, 57.4 years). Aneurysmal locations were found in the MCA, ICA, and ACA in 23, 19, and 18 patients, respectively. …”
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Risk Factors for Hemorrhagic Stroke among Adults in the Democratic Republic of the Congo: A Hospital-Based Study in a Limited Resource Setting by Jacques Mbaz Musung, Placide Kambola Kakoma, Marcellin Bugeme, Jeef Paul Munkemena Banze, Clarence Kaut Mukeng, Orly Ngungwa Muyumba, Berthe Mwad Kamalo, Harvey Kabulo Kapya, Ghyslain Lambo Ngongo, Laurent Kitwa, Evariste Tshibind Yav, Olivier Mukuku, Emmanuel Kiyana Muyumba

“…Of which 41.1% (65/158) were women. The mean age was 60.8±13.3 years. Main clinical signs were hemiplegia (63.3%), headache (48.7%), speech disorders (38.6%), and dizziness (38.6%). …”
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Characteristics Associated with Acute-Phase Response following First Zoledronic Acid Infusion in Brazilian Population with Osteoporosis by Bruno S. A. Ferreira, Bernardo M. da Cunha, Luciana P. Valadares, Larissa A. Moreira, Frederico G. A. Batista, Cristiane da F. Hottz, Marina M. P. Lins, Gabriel G. R. Magalhães, Luanna M. de Arruda, Sergio H. R. Ramalho

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Autologous haematopoiesis stem cell transplantation (AHSCT) for treatment-refractory autoimmune diseases in children by Jasmin Beate Kuemmerle-Deschner, Susanne Benseler, Joerg C Henes, Özlem Satirer, Michaela Döring, Till Lesk

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Development and Evaluation of an AI-based Exergame Training System for Ice-Hockey Players: a Randomized Controlled Trial by Nicole Sieber, Simon Walser, Thomas Weber, Raphael Gubler, Hannes Badertscher, Patrick Eggenberger

“…Half of each team’s players were randomly assigned to either the exergame intervention (n=18, female n=5, mean age 20.6 ± 5.0 years) or control group (n=18, female n=5, mean age 20.0 ± 5.8 years). …”
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Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease by Misun Hwang, Dana L. Tudorascu, Karen Nunley, Helmet Karim, Howard J. Aizenstein, Trevor J. Orchard, Caterina Rosano

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Cross-cultural adaptation: South African Gestational Diabetes Mellitus Knowledge Questionnaire by Lorisha Manas, Tawanda Chivese, Ankia Coetzee, Magda Conradie, Linzette D. Morris

“…Methods: A prospective, observational study was conducted at a high-risk antenatal clinic in South Africa. Pregnant women ≥ 18 years with GDM were consecutively sampled. …”
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A machine learning-based radiomics approach for differentiating patellofemoral osteoarthritis from non-patellofemoral osteoarthritis using Q-Dixon MRI by Liangjing Lyu, Jing Ren, Wenjie Lu, Jingyu Zhong, Yang Song, Yongliang Li, Weiwu Yao

“…This diagnostic accuracy study retrospectively analyzed data from 215 patients (mean age: 54.2 ± 11.3 years; 113 women). Three predictive models were evaluated: a proton density-weighted image model, a fat fraction model, and a merged model. …”
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Complications In The Management Of High-Energy Closed Fractures Of Proximal Tibial Plateau. A Retrospective Study by Rahman Rasool Akhtar, Waqas Ali, Riaz Ahmed, Muhammad Nadeem Kashmiri, Hira Waris, Muhammad Haider

“…Each patient received treatment using techniques such as internal fixation with locking plates and open reduction which are minimally invasive. …”
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Impact of high hemoglobin levels on carotid artery intima–media thickness and its predictive value for hypertension in high-altitude areas: a real-world study by Long Hongyu, Long Ga, Zhang Yiqian, Xu Qiuyu, Li Kemin, Qing Maiyongcuo, Xiong Min

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Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study by Songjing Chen, Sizhu Wu

“…Men ≥ 65 carrying C > A/G > T mutation had the highest lung cancer incidence decrease of 39.5% after five years quitting in stratified elderly groups, which were 1.83 times more than women ≥ 65 not carrying C > A/G > T mutation. …”
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Nerve Enlargement in Patients with INF2 Variants Causing Peripheral Neuropathy and Focal Segmental Glomerulosclerosis by Quynh Tran Thuy Huong, Linh Tran Nguyen Truc, Hiroko Ueda, Kenji Fukui, Koichiro Higasa, Yoshinori Sato, Shinichi Takeda, Motoshi Hattori, Hiroyasu Tsukaguchi

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Trajectories of self-rated health in an older general population and their determinants: the Lifelines Cohort Study by Barbara C van Munster, Nynke Smidt, Sophia E de Rooij, Marlies Feenstra, Janet L MacNeil Vroomen

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Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study by Yi-Ting Huang, Yao-Chun Hsu, Hwai-I Yang, Mei-Hsuan Lee, Tai-Hsuan Lai, Chien-Jen Chen, Yen-Tsung Huang

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Reference intervals for thyroid-stimulating hormone in the adult Lebanese population: Results from the last decade by Elie Naous, Riam Hijazi, Marianne Chalhoub, Nada El Ghorayeb, Marie-Hélène Gannagé-Yared

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Own Experience in the Use of Artificial Intelligence Technologies in the Diagnosis of Esophageal Achalasia by O. A. Storonova, N. I. Kanevskii, A. S. Trukhmanov, V. T. Ivashkin

“…The study included 75 patients: 52 % men (mean age 44.5 ± 17.8 years) and 48 % women (mean age 45.6 ± 16.6 years,) with a preliminary diagnosis of achalasia. …”
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Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan [version 2; peer review: 1 approved, 2 approved with reservations] by Yuho Shimizu, Hiroyuki Suzuki, Tomoki Furuya, Ai Iizuka, Keigo Hinakura, Tomoya Takahashi, Yan Li, Daichi Yamashiro, Yoshifumi Takahashi, Daisuke Cho, Susumu Ogawa, Kenichiro Sato

“…Data from 285 participants (264 women, M = 71.97 years) were analyzed. Results The intraclass correlation coefficient for life satisfaction concerning residential areas was. 03 (95% confidence interval [CI] = [-.03, .10]). …”
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User Experience of a Semi-Immersive Musical Serious Game to Stimulate Cognitive Functions in Hospitalized Older Patients: Questionnaire Study by Laurent Samson, Lena Carcreff, Frédéric Noublanche, Sophie Noublanche, Hélène Vermersch-Leiber, Cédric Annweiler

“…ResultsOverall, 60 inpatients with a mean age of 84.2 (SD 5.5) years, the majority of whom were women (41/60, 68%), were included. …”
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