Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. Information of cancer patients was retrospectively collected from three cancer centers in China.Results: Totally, 198 HR+/HER2- ABC patients with complete records in expression rates (%) of ER, PR and Ki67 were enrolled in the study. …”
Get full text

Analisis Strategi Pemasaran Politik Kampanye Kukuh Haryanto Sebagai Calon Legislatif DPRD Kabupaten Wonogiri Dalam Kontestasi Pemilihan Umum Tahun 2024 by Shildamullah Danendra Mukti Ardana, Titin Purwaningsih

“…The research adopts a qualitative method, with primary data collected through direct interviews with informants and secondary data sourced from the internet, mass media, journal articles, and previous studies relevant to the topic. …”
Get full text

Attention to Monkeypox: An Interpretable Monkeypox Detection Technique Using Attention Mechanism by Avi Deb Raha, Mrityunjoy Gain, Rameswar Debnath, Apurba Adhikary, Yu Qiao, Md. Mehedi Hassan, Anupam Kumar Bairagi, Sheikh Mohammed Shariful Islam

Get full text

Evaluation and Management of Patients with Seizures in the Emergency Department: A One-Year Analysis by K. Puteikis, K. Zdanytė, R. Mameniškienė

“…The evaluative practices and care complied with selected international guidelines in most cases, except for some approaches related to neuroimaging and information deliverance. …”
Get full text

Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

“…As many as 80% of these deaths from COPD occur in low- and middle-income countries. COPD is usually characterized by difficulty breathing and coughing accompanied by phlegm. …”
Get full text

Producción y calidad del trigo candeal (Triticum turgidum L. subsp. durum) en Argentina: análisis del quinquenio 2014/2018 by Elena Rosa MOLFESE, N. FRITZ

“…Desde entonces, anualmente se realiza la publicación de un informe de cosecha donde se vuelcan datos de calidad de los granos y las sémolas. …”
Get full text

An Explainable Artificial Intelligence Text Classifier for Suicidality Prediction in Youth Crisis Text Line Users: Development and Validation Study by Julia Thomas, Antonia Lucht, Jacob Segler, Richard Wundrack, Marcel Miché, Roselind Lieb, Lars Kuchinke, Gunther Meinlschmidt

“…We subsequently computed discrimination, calibration, clinical utility, and explainability information using a Shapley Additive Explanations value-based post hoc estimation model. …”
Get full text

Analisis Perpindahan Wisatawan dan Preferensi Desrinasi Wisata Favorit Berdasarkan Geotag Instagram (Studi Kasus pada Destinasi Wisata Bandung Raya) by Herry Irawan, Eva Nurhazizah, Joe Nathan C.G. Panjaitan

“…Several steps were taken by the West Java Provincial Government in order to increase tourist visits, one of which was the application of communication and information technology or known as the concept of smart tourism. …”
Get full text

Peningkatan Akurasi Metode Weighted Fuzzy Time Series Forecasting Menggunakan Algoritma Evolusi Differensial dan Fuzzy C-Means by Agus Fachrur Rozy, Solimun Solimun, Ni Wayan Surya Wardhani

“…The data used in this research is the Jakarta Islamic Index (JKII) on a monthly basis from August 2018 to July 2023. The information collected is secondary data obtained from the website www.yahoo.finance.com. …”
Get full text

Multi-task aquatic toxicity prediction model based on multi-level features fusion by Xin Yang, Jianqiang Sun, Bingyu Jin, Yuer Lu, Jinyan Cheng, Jiaju Jiang, Qi Zhao, Jianwei Shuai

Get full text

2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity by Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri, Pascal Marchand, Francisco Jaime Bezerra Mendonça-Junior

Get full text

Modification of metal-cutting plates from tungsten-free hard alloy grade KNT16 by continuous ion beams by A. M. Badamshin, S. N. Povoroznuyk, V. V. Akimov, E. A. Rogachev, A. A. Krutko

Get full text

Diseño e implementación de mejoras aplicando la norma ISO/IEC 25000 para la calidad de software en un sistema de gestión bibliotecario by Pedro Damián González Villalba, Hugo David Ortega Domínguez

“…Para la investigación, se adoptó una metodología de investigación de tipo aplicada, con un diseño no experimental, y un enfoque cualitativo, dado que las variables de investigación no fueron manipuladas, sino más bien para comprender de manera más detallada las necesidades que los usuarios presentaron desde la implementación del SIGB. …”
Get full text

Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

Get full text

Faktor-faktor yang Berhubungan dengan Tingkat Pengetahuan Wanita Usia Subur Tentang “SADARI” di Nagari Painan by Vitro Darma Yusra, Rizanda Machmud, Yenita Yenita

“…Processing data using univariate and bivariate analysis with the chi-square statistic test.The result of this research showed that the factors associated with the level of knowledge about BSE of infertile women in Nagari Painan on 2014 are: level of education (OR=11.421, 95 % CI : 2.620 to 49.791), job (OR=3.058, 95% CI:1.416 to 6.604), Sources of information (OR=10.011, 95% CI: 2.915 to 34.375), family (OR=6.346, 95% CI:2.318 to 17.370) and factors that are not related to the level of knowledge of infertile women on BSE (OR=1,428, CI 95%:0.688- 2962).The conclusion of this research is the level of education is the most influential factor to the level of knowledge of infertile women of about BSE in Nagari Painan 2014. …”
Get full text

Prognostic factors of thalamic and thalamopeduncular low-grade gliomas in children: A systematic review and recommendations for surgical management by Jana Táborská, Adéla Bubeníková, Petr Skalický, Jakub Táborský, David Horváth, Michal Zápotocký, Ondřej Bradáč, Vladimír Beneš, 3rd

Get full text

Blockchain-Based Value-Added Tax System: A Systematic Review by Vahideh Ghanooni Shishavan, Shaban Elahi, Sadegh Dorri Nogoorani, Ali Yazdian Varjani

Get full text

Estimación de volúmenes de sedimentos por erosión hídrica empleando el modelo RUSLE en cuencas de la provincia de Manabí, Ecuador by Gema Casanova-Ruiz, Daniel Delgado, Ramona Panchana

“…En los últimos años se han desarrollado varios métodos para cuantificar los sedimentos, pero su complejidad, precisión y exactitud varía dependiendo del enfoque empleado. Sin embargo, muchos de estos modelos requieren de la utilización de extensas series temporales de precipitaciones, pero, en Ecuador, las estaciones meteorológicas presentan una preocupante carencia de datos y su distribución espacial no es homogénea, lo que genera una incorrecta estimación de las lluvias en el territorio analizado. …”
Get full text

Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…The public and investors who want to access RSPA information directly go to the DPUPR-Perkim office. …”
Get full text

Psychological peculiarities of professional development in late adulthood by E. F. Zeer, E. E. Symanyuk, A. A. Ryabukhina, G. I. Borisov

“…Modern technologies are generating new types of production and transformation of old ones, which results in the loss of jobs, income and status among the representatives of elder generation and leads to a professional loss crisis. …”
Get full text