Knowledge, attitudes and practices of oral HIV pre-exposure prophylaxis (PrEP) among healthcare workers in the Ekurhuleni District, South Africa by E Mahlare, E Ramutshila, A Musekiwa, L Kuonza, T Mabuto

“…We conducted a cross-sectional interviewer-administered survey among healthcare workers from 45 randomly selected PHCs in Ekurhuleni District. We collected information on participant characteristics and their KAPs regarding HIV PrEP service delivery. …”
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Polymorphic variants of the genes for enzymes of the antioxidant system, apoptosis and inflammation as potential predictors of myocardial infarction by T. R. Nasibullin, V. V. Erdman, Y. R. Timasheva, I. A. Tuktarova, A. A. Petinseva, G. F. Korytina

“…The purpose of the study was to search for informative predictors of MI risk based on polygenic analysis of polymorphic variants of (1) the antioxidant defense enzyme genes PON1 (rs662), PON2 (rs7493), CAT (rs1001179), MSRA (rs10098474) and GSTP1 (rs1695); (2) the apoptosis genes CASP8 (rs3834129), TP53 (rs1042522) and BCL2 (rs12454712); and (3) the inflammation genes CRP (rs1205), CX3CR1 (rs3732378), IL6 (rs1800795) and CCL2 (rs1024611). 591 DNA samples were used in the study (280 patients with the onset at 30 to 60 years, with an average age of 46.02 ± 6.17, and 311 control subjects aged 30 to 62, with an average age of 44.65 ± 7.07). …”
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The Effectiveness of Rapamycin Combined with Eltrombopag in Murine Models of Immune-Mediated Bone Marrow Failure by Shaoxue Ding, Xiaowei Liang, Tian Zhang, Rong Fu

“…In this study, an immune attack-mediated AA mouse model was constructed by total body irradiation (TBI) and allo-lymphocyte infusion. In our study, we tested the efficacy of Rapa combined with Elt as a new treatment in mouse models of immune-mediated bone marrow failure. …”
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Diez años del “Programa de evaluación de desempeño de laboratorios de inmunogenética” y su impacto en la “Red de donación y trasplantes” by yazmin rocio arias-murillo, María Angélica Salinas-Nova, Yesith Guillermo Toloza-Pérez, Miguel Ángel Castro-Jiménez

“…Se recolectaron los datos de los informes de cada laboratorio. Con base en las comparaciones entre laboratorios, se calificó el desempeño de cada uno como «bueno», «aceptable» o «inaceptable» para cada prueba. …”
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RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study by Yanju Li, Xu Yang, Feiqing Wang, Feiqing Wang, Jianing Zhao, Chike Zhang, Dan Wu, Bo Yang, Rui Gao, Peng Zhao, Yun Zan, Min Su, Zhixu He, Yang Liu, Yang Liu, Yang Liu, Jishi Wang, Dongxin Tang

“…Cell experiments showed that asparagus, through the PI3K/AKT/NF-κB pathway, inhibited the proliferation and migration of MM cells, and caused retardation and apoptosis of MM cells in the G0/G1 phase.Discussion: In this study, the anti-cancer activity of asparagus against MM was demonstrated using network pharmacology, and potential pharmacological mechanisms were inferred using in vitro experimental data.…”
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Longitudinal genetic studies of cognitive characteristics by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, S. B. Malykh, E. K. Khusnutdinova

“…They can explain the mechanism of transgenerational transfer of information on cognitive abilities. Recently, large-scale meta-analyses based on the results of studies, which identified genetic associations with various cognitive traits, were carried out. …”
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The long-term impact of childhood sexual assault on depression and self-reported mental and physical health by Oluwasegun Akinyemi, Temitope Ogundare, Mojisola Fasokun, Fadeke Ogunyankin, Nkemdirim Ugochukwu, Walia Ajisafe, Seun Ikugbayigbe, Oluebubechukwu Eze, Kakra Hughes, Miriam Michael

“…The findings underscore the cumulative impact of multiple CSA exposures on health outcomes and emphasize the need for trauma-informed healthcare, early intervention, and public health strategies to mitigate the long-term consequences of CSA.…”
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Body image and attitudes toward cosmetic surgeries among female college students in the United Arab Emirates: A cross-sectional study by Ahmad M. Al-Bashaireh, Yousef Aljawarneh, Osama Alkouri, Foad Alzoughool, Amal Alhefeiti, Amnah Aldhuhoori, Amnah Al Kaabi, Aseilah Alkaabi, Fawzia Alnaqbi

“…Moreover, a culturally tailored educational campaign is needed to enhance students' capacity for making informed decisions and instill a conscientious approach to personal health and aesthetic considerations.…”
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Single-cell RNA sequencing highlights the role of distinct natural killer subsets in sporadic amyotrophic lateral sclerosis by Esther Álvarez-Sánchez, Álvaro Carbayo, Natalia Valle-Tamayo, Laia Muñoz, Joaquim Aumatell, Soraya Torres, Sara Rubio-Guerra, Jesús García-Castro, Judit Selma-González, Daniel Alcolea, Janina Turon-Sans, Alberto Lleó, Ignacio Illán-Gala, Juan Fortea, Ricard Rojas-García, Oriol Dols-Icardo

“…We also identified gene expression changes in other immune cells, such as classical monocytes, and distinct CD8 + effector memory T cells which suggested enhanced antigen presentation via major histocompatibility class-II (adj. p-value = 1.23 × 10− 8) in ALS. The inference of cell-cell communication patterns demonstrated that the interaction between HLA-E and CD94:NKG2C from different lymphocytes to NK_2 cells is unique to ALS blood compared to HC. …”
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Association of lipid accumulation product index with self-reported diabetes among residents aged 18 – 44 years in Hebei province, 2020: a surveillance data analysis by Qi QI, Lijuan TANG, Yuhuan LIU, Jinchai GAO, Xiuli NIU, Qianyu LI, Shifan WANG, Xiaoli LIU, Ze CUI

“…After adjusting for age, ethnicity, education level, marital status, employment, annual household income per capita, place of residence, smoking, alcohol consumption, and physical activity, unconditional multivariate logistic regression analysis showed that, compared with those with LAP index in the lowest quartile, male residents with LAP index in the second, third, and highest quartiles had an increased risk of self-reported diabetes, with odds ratios (95% confidence interval) of 7.78 (2.33, 26.01), 12.74 (3.90, 41.63), and 34.38 (10.75, 109.93), respectively, while female residents with LAP index in the highest quartile had an increased risk of self-reported diabetes (odds ratio = 11.32, 95% confidence interval: 4.76, 26.96) compared with those with LAP index in the lowest quartile. …”
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Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity by Yang Wang, Jianguo Xu, Wanchun You, Haitao Shen, Xiang Li, Zhengquan Yu, Haiying Li, Gang Chen

“…The SAH rat model was induced by infusing autologous blood into the optic chiasma pool and treating the rats with lentivirus-negative control 1 (LV-NC1), lentivirus-Rufy3 shRNA (LV-shRNA), lentivirus-negative control 2 (LV-NC2), lentivirus-Rufy3 (LV-Rufy3), or 8-pCPT-2′-O-Me-cAMP (8p-CPT) (Rap1 agonist). …”
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Provide a Framework for the Application of Open Policy Making in Parliament of Iran by Mohsen Eynali, Seyed Abbas Ebrahimi, Mohsen Farhadinejad, Hasan Danaeefard

“…ObjectiveOpen policy making represents an innovative and modern approach for governments to create and deliver policies that are effectively aligned with the rapid changes and evolving demands of a fast-paced, digital world. …”
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Physical activity, fatigue severity, and health-related quality of life of community-dwelling stroke survivors: a cross-sectional study by Marufat Oluyemisi Odetunde, Ayomide Felix Makinde, Olamide Mary Jimoh, Chidozie Emmanuel Mbada, Faatihah Niyi-Odumosu, Francis Fatoye

“…PA, FS, and HRQL of the SSV were assessed using the Stroke Physical Activities Questionnaire (SPAQ), Fatigue Severity Scale (FSS), and Stroke-Specific Quality-of-Life (SS-QoL) scale, respectively. Information on respondents’ socio-demographic and clinical characteristics was also collected. …”
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Ambulatory Surgery for Perianal Crohn’s Disease: Study of Feasibility by S. Sibio, A. Di Giorgio, M. Campanelli, S. Di Carlo, A. Divizia, C. Fiorani, R. Scaramuzzo, C. Arcudi, G. Del Vecchio Blanco, L. Biancone, G. Sica

“…The data of patients were prospectively collected for three years (February 2014 to February 2017) for the purpose of the study. All clinical information, including previous EUA and/or records from MRI and endoscopic ultrasound, was included. …”
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Comprehensive analysis of endoscopic ultrasound (EUS) in mediastinal lesions: patient characteristics, diagnostic outcomes, safety, and efficacy: a multi-country study by Hussein Okasha, Eyad Gadour, Ghias Un Nabi Tayyab, Andrada Seicean, Elbacha Hicham, Emad Emad, Turki Alamri, Nadeem Tehami, Heero Ismael Faraj, Ahmed Alzamzamy, Hiwa Hussein, Mohammed Tag-Adeen, Mohamed Elbasiony, Abed Al-Lehibi, Shereen Saleh, Zaher Houmani, Mohamed Abdelghani, Khaled Ragab, Zahi Ismaili, Othmane Drir, Elsayed Ghoneem, Omar Abdallah, Souad Rebiai, Nonthalee Pausawasdi, Fedoua Rouibaa, Mohamed Borahma, Hassan Atalla, Mahmoud Farouk, Ahmed Altonbary

“…Methods This multi-country study involved a list of centers providing EUS services across ten countries—the United Kingdom, Algeria, Egypt, Iraq, Kingdom of Saudi Arabia (KSA), Lebanon, Morocco, Pakistan, Romania, and Thailand. The appropriate information was collected regarding EUS-FNA and EUS-FNB procedures, including needle types, nature of lesion, needle passes, and complications of the techniques. …”
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Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm by Dong Jiang, Yi Qian, Yijun Gu, Ru Wang, Hua Yu, Zhenmeng Wang, Hui Dong, Dongyu Chen, Yan Chen, Haozheng Jiang, Yiran Li

“…CEUS has a high accuracy rate in diagnosing the benign or malignant nature of gallbladder space-occupying lesions, which can significantly reduce the preoperative waiting time for related examinations and provide more reliable diagnostic information for clinical practice. Results Feature selection via Lasso led to a final LR model incorporating high-density lipoprotein, smoking status, basal width, and Rad_Signature. …”
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Treatment outcomes and associated factors among patients with multidrug-resistant tuberculosis in Ashanti Region, Ghana: a retrospective, cross-sectional study by Peter Agyei-Baffour, Victoria Panford, Emmanuel Kumah, Collins Kokuro, Prince Owusu Adoma, Michael Afari Baidoo, Adam Fusheini, Samuel Egyakwa Ankomah, Samuel Kofi Agyei

“…The regional MDR-TB register, which contains information on all patients with MDR-TB being treated at the various TB centres in the region, was analysed between February and May 2021.Participants The participants consisted of all registered patients with MDR-TB who were placed on treatment between 1 January 2015 and 31 December 2020. …”
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Association between sperm motility in thawed semen and pregnancy rate in Mediterranean buffaloes by Armando Quintero-Moreno, Carla Osorio Meléndez, Héctor Nava-Trujillo, Jorge Rubio Guillén, Juan Carlos Gutiérrez-Añez, Adriana Camacho de Gutiérrez

“… Progressive individual motility is the main parameter used to determine the reproductive potential of a buffalo bull. This information contributes to deciding to use and process or not the ejaculate obtained and therefore assume that the spermatozoa from the seminal sample could achieve pregnancy in inseminated buffaloes. …”
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Intracranial complications in adult patients with severe pneumococcal meningitis: a retrospective multicenter cohort study by Camille Legouy, Renaud Cornic, Keyvan Razazi, Damien Contou, Stéphane Legriel, Eve Garrigues, Pauline Buiche, Maxens Decavèle, Sarah Benghanem, Thomas Rambaud, Jérôme Aboab, Marina Esposito-Farèse, Jean-François Timsit, Camille Couffignal, Romain Sonneville

“…This study highlights the value of neuroimaging studies in this population, and provides relevant information for prognostication.…”
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Biofloc technology significantly reshapes water microbiome and improves survival rates in Japanese eel (Anguilla japonica) by Jiho Yang, Hyunjun Choi, Jun Seong Park, Yehyeon Cha, Ju-Ae Hwang, Seung-Yoon Oh

“…To identify the operational taxonomic units (OTUs) that directly influence the feed consumption rate of eels, closely linked to their growth rate, we first determined the differentially abundant residents and then highlighted the most informative OTUs. In summary, our analysis identified microbial residents potentially associated with the higher growth rates observed in BFT-treated eels, highlighting the need for further functional studies.IMPORTANCEThis study is significant as it addresses a critical gap in the application of Biofloc Technology (BFT) to Japanese eel (Anguilla japonica) aquaculture, a high-value species in East Asia. …”
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