Trends in stroke-related mortality in atrial fibrillation patients in the United States: Insights from the CDC WONDER database by Muhammad Abdullah Naveed, Sivaram Neppala, Himaja Dutt Chigurupati, Muhammad Omer Rehan, Ahila Ali, Hamza Naveed, Bazil Azeem, Rabia Iqbal, Manahil Mubeen, Mashood Ahmed, Ayman R. Fath, Timir Paul, Bilal Munir

“…Deaths occurred predominantly in medical facilities (43.2 %). The overall AAMR for AF-associated stroke decreased from 7.4 in 1999 to 6.4 in 2020, with an APC of −1.02 (p-value = 0.004). …”
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Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus by Asif Hameed, Francesca McDonagh, Pratyay Sengupta, Georgios Miliotis, Shobhan Karthick Muthamilselvi Sivabalan, Lukasz Szydlowski, Anna Simpson, Nitin Kumar Singh, Punchappady Devasya Rekha, Karthik Raman, Kasthuri Venkateswaran

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies by Prathibha Babu Chandraprabha, Manoj Kumar K. Azhagiri, Vigneshwaran Venkatesan, Wendy Magis, Kirti Prasad, Sevanthy Suresh, Aswin Anand Pai, Srujan Marepally, Alok Srivastava, Kumarasamypet Murugesan Mohankumar, David I. K. Martin, Saravanabhavan Thangavel

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A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Despite its accessibility and wider coverage of public health insurance, the integrated service model in Indonesia faces challenges associated with complex regulations and the availability of medication. …”
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Unexpected placenta accreta spectrum in an unscarred uterus causing catastrophic post-partum hemorrhage: a case report and review of the literature by Priyanka Garg, Shweta Semwal, Romi Bansal

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Role of Gut and Urinary Microbiome in Children with Urinary Tract Infections: A Systematic Review by Anjali Srivastava, Omprakash Shete, Annu Gulia, Sumit Aggarwal, Tarini Shankar Ghosh, Vineet Ahuja, Sachit Anand

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Healthcare access, attitudes and behaviours among Navajo adults during the COVID-19 pandemic: a cross-sectional study by Robin B Harris, Carmenlita Chief, Heidi E Brown, Rachelle L Begay, Priscilla R Sanderson, Breanna Lameman

“…Positive tests were not associated with household size or multigenerational homes, though time to grocery store was (p=0.04). …”
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Quit attempts among tobacco users identified in the Tamil Nadu Tobacco Survey of 2015/2016: a 3 year follow-up mixed methods study by Jaya Prasad Tripathy, Abhay Nirgude, Surendran Veeraiah, Vidhubala Elangovan, Arvind Krishnamurthy, Tanu Anand, Mahendra M Reddy, Revathy Sudhakar, Niraimathi K, Divyarajprabhakar Subramani, Swaminathan Rajaraman, Hemanth Raj Elluswami

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TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART by HariOm Singh, Dharmesh Samani, Sumit Aggarwal

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Assessment of Birth Preparedness and Complication Readiness among Pregnant Women: A Cross-sectional Study by T Elamathi, K Ananthi, Rimi Singh

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Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI by Vaanathi Sundaresan, Giovanna Zamboni, Robert A. Dineen, Dorothee P. Auer, Stamatios N. Sotiropoulos, Nikola Sprigg, Mark Jenkinson, Ludovica Griffanti

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A multicenter, cross‐sectional analysis to assess the safety and usage pattern of brivaracetam in the management of partial‐onset seizure with BAEs—BREEZE study: A post‐hoc analysi... by Arvind Sharma, Krishnaprasad Korukonda, Amit Haldar, Usha Kant Misra, R. V. Anand, Yakshdeep Dave, Girish Kulkarni

“…Abstract Objective Brivaracetam (BRV), a third‐generation anti‐seizure medication (ASM) offers strong conformational receptor domain binding, faster blood brain barrier (BBB) permeability and better tolerability making it potential therapeutic option as an initial line or initial line add‐on strategy for focal onset seizure (FoS). …”
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Comparison of Hyperbaric 0.5% Levobupivacaine and Hyperbaric 0.75% Ropivacaine for Intrathecal Use in Infraumbilical Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Priya Kishnani, Richa Tailor, Sara Mary Thomas

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Correlates of access to sanitation facilities and benefits received from the Swachh Bharat Mission in India: analysis of cross-sectional data from the 2018 National Sample Survey by Pradeep Kumar, Sayeed Unisa, Srayasi Prakash, Preeti Dhillon

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Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer by Eeshrita Jog, Ashwin Kumar Jainarayanan, Alessandro La Ferlita, Arnab Chakraborty, Afiya Dalwai, Showket Yahya, Anusha Shivashankar, Bhagya Shree Choudhary, Aakash Chandramouli, Mufaddal Kazi, Darshan Jain, Nileema Khapare, Akshaya B, Bushra K. Khan, Poonam Gera, Prachi Patil, Rahul Thorat, Nandini Verma, Lalit Sehgal, Avanish Saklani, Siddhesh S. Kamat, Sorab N. Dalal, Nazia Chaudhary

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4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…Chronic inflammatory diseases such as periodontitis have been associated with increased risk for various medical conditions including diabetes and cardiovascular disease. …”
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Effect of probiotic and prebiotics supplementation on hemoglobin levels and iron absorption among women of reproductive age and children: a systematic review and meta-analysis by Aditi Apte, Ashwini Parge, Radhika Nimkar, Anju Sinha

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Socio-economic assessment of dog population management systems: a scoping review by Rabina Ghimire, Parimala Mohanty, Elly Hiby, Andrew Larkins, Andrew Larkins, Salome Dürr, Sonja Hartnack

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Factors influencing trust in algorithmic decision-making: an indirect scenario-based experiment by Fernando Marmolejo-Ramos, Rebecca Marrone, Malgorzata Korolkiewicz, Florence Gabriel, George Siemens, Srecko Joksimovic, Yuki Yamada, Yuki Mori, Talal Rahwan, Maria Sahakyan, Belona Sonna, Assylbek Meirmanov, Aidos Bolatov, Bidisha Som, Izuchukwu Ndukaihe, Nwadiogo C. Arinze, Josef Kundrát, Lenka Skanderová, Van-Giang Ngo, Giang Nguyen, Michelle Lacia, Chun-Chia Kung, Meiselina Irmayanti, Meiselina Irmayanti, Abdul Muktadir, Fransiska Timoria Samosir, Marco Tullio Liuzza, Roberto Giorgini, Omid Khatin-Zadeh, Hassan Banaruee, Asil Ali Özdoğru, Kris Ariyabuddhiphongs, Wachirawit Rakchai, Natalia Trujillo, Stella Maris Valencia, Armina Janyan, Armina Janyan, Kiril Kostov, Pedro R. Montoro, Jose Hinojosa, Jose Hinojosa, Kelsey Medeiros, Thomas E. Hunt, Julian Posada, Raquel Meister Ko Freitag, Julian Tejada

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Antimicrobial resistance (AMR) and spread of New Delhi Metallo-β-Lactamase (NDM) in Italy: A call for policymakers by Gabriella Nucera

“…Since its first description in 2008 from a Klebsiella pneumoniae strain isolated from a patient repatriated to Sweden after hospitalisation in New Delhi, India, NDM-positive strains have been identified worldwide, with the highest prevalence in the Indian subcontinent, causing healthcare-associated outbreaks worldwide [5]. …”