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IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with lim...
Published 2024-12-01“…In vivo we show that IL-2-armored GPS, but not the corresponding GPS, effectively expands grafted CMVpp65 CD8+ T cells from unstimulated human PBMCs in an NSG mouse model. …”
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Influence of Epinastine Hydrochloride, an H1-Receptor Antagonist, on the Function of Mite Allergen-Pulsed Murine Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo
Published 2009-01-01“…The aim of the present study was to examine the effect of epinastine hydrochloride (EP), the most notable histamine H1 receptor antagonists in Japan, on Dermatophagoides farinae (Der f)-pulsed mouse bone marrow-derived DCs in vitro and in vivo. EP at more than 25 ng/mL could significantly inhibit the production of IL-6, TNF-𝛼 and IL-10 from Der f-pulsed DCs, which was increased by Der f challenge in vitro. …”
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Effectively alleviate rheumatoid arthritis via maintaining redox balance, inducing macrophage repolarization and restoring homeostasis of fibroblast-like synoviocytes by metformin-...
Published 2025-01-01“…In vivo therapeutic investigation suggested that MCDs reduced synovial inflammation and hyperplasia, ultimately prevented cartilage destruction, bone erosion, and synovial fibrosis in CIA rats. …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid...
Published 2024-12-01“…Enzyme-linked immunosorbent assay measured IL-1β, IL-6, and TNF-α levels. Immunofluorescence (IF) staining visualized NF-κB and IRF3 translocation. …”
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TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo
Published 2016-01-01“…TNFR1 blockade did not change the cell surface expression of TNFR2, leaving this receptor free to upregulate IL-10. …”
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Analysis of the Cytokine Expression in the Aqueous Humor of Individuals with BRVO-Associated Macular Edema
Published 2022-01-01“…This study suggests that the severity of ME in BRVO-ME patients is significantly correlated with the expression levels of IL-6, VEGF, ICAM-1, and VCAM-1 in the aqueous humor. …”
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3D printed biodegradable hydrogel-based multichannel nerve conduits mimicking peripheral nerve fascicules
Published 2025-04-01Get full text
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Mesure de la digestibilité <em>in vivo</em> de résidus de récolte de quatre variétés améliorées de sorgho à double usage sur les moutons de race Djallonké
Published 2024-12-01“…Les plus fortes valeurs de dMS, dMO et dMAT ont été obtenues avec la variété Zalatimi avec 44,4 %, 43,5 % et 42,4 % respectivement. …”
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Ma quanto sono nuovi i novel food?
Published 2025-01-01“…Il secondo elemento deriva dal fatto che il dibattito politico, non solo in Italia, anziché soffermarsi sulla necessità di intervenire affinché sia garantito un cibo non solo di qualità, ma anche sostenibile, tratta il tema degli insetti edibili e più in generale dei novel food come una bandiera per ribadire la superiorità della cultura nazionale ed europea.…”
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Immunoprotective effect of chitosan nanoparticles with different particle sizes against H9N2 avian influenza infection
Published 2025-01-01“…H9N2 is the most common avian influenza virus (AIV), which causes significant losses in chickens. …”
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