Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality by Fernando García-García, Dae-Jin Lee, Mónica Nieves-Ermecheo, Olaia Bronte, Pedro Pablo España, José María Quintana, Rosario Menéndez, Antoni Torres, Luis Alberto Ruiz Iturriaga, Isabel Urrutia, COVID-19 & Air Pollution Working Group

“…Our clustering algorithm identified k=3 distinct phenotypes and 18 strongly informative variables: Phenotype A (788 cases [50.9% prevalence] – age $$\sim$$ ∼ 57, Charlson comorbidity $$\sim$$ ∼ 1, pneumonia CURB-65 score $$\sim$$ ∼ 0 to 1, respiratory rate at admission $$\sim$$ ∼ 18 min-1, FiO2 $$\sim$$ ∼ 21%, C-reactive protein CRP $$\sim$$ ∼ 49.5 mg/dL [median within cluster]); phenotype B (620 cases [40.0%] – age $$\sim$$ ∼ 75, Charlson $$\sim$$ ∼ 5, CURB-65 $$\sim$$ ∼ 1 to 2, respiration $$\sim$$ ∼ 20 min-1, FiO2 $$\sim$$ ∼ 21%, CRP $$\sim$$ ∼ 101.5 mg/dL); and phenotype C (140 cases [9.0%] – age $$\sim$$ ∼ 71, Charlson $$\sim$$ ∼ 4, CURB-65 $$\sim$$ ∼ 0 to 2, respiration $$\sim$$ ∼ 30 min-1, FiO2 $$\sim$$ ∼ 38%, CRP $$\sim$$ ∼ 152.3 mg/dL). …”
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Heart failure with mildly reduced ejection fraction: retrospective study of ejection fraction trajectory risk by Robert J.H. Miller, Majid Nabipoor, Erik Youngson, Gynter Kotrri, Nowell M. Fine, Jonathan G. Howlett, Ian D. Paterson, Justin Ezekowitz, Finlay A. McAlister

“…Categorizing HFmrEF patients based on LVEF trajectory provides meaningful clinical information and may assist clinicians with management decisions.…”
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gp91phox, a Novel Biomarker Evaluating Oxidative Stress, Is Elevated in Subclinical Hypothyroidism by Xiaochun Ma, Furong Wang, Xiaowen Zhen, Lifang Zhao, Li Fang, Zhenfang Dong, Wenbin Chen, Xiaoming Zhou

“…All the patients were newly diagnosed and did not take any medication. The information of lipid profile and thyroid function was extracted, and the concentrations of gp91phox were obtained with ELISA. …”
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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Trial sequential analysis showed that we did not have enough information to assess the effects of duloxetine on serious adverse events (SAEs) (OR 0.67, 95% CI 0.44 to 1.02; I2=0.0%; 19 trials) or suicide or suicide attempts (OR 1.08, 95% CI 0.37 to 3.16; six trials). …”
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Carriage of Extended-Spectrum-β-Lactamase- and AmpC-β-Lactamase-Producing Enterobacteriaceae (ESBL-PE) in Healthy Community and Outpatient Department (OPD) Patients in Nepal by Dipendra Kumar Mandal, Shiv Kumar Sah, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sanjeet Pandit, Pranav Kumar Yadav, Ujjwal Laghu, Rajani Lama, Niranjan Prasad Sah, Jeevan Bahadur Sherchand, Keshav Parajuli, Anup Bastola, Sher Bahadur Pun, Basista Prasad Rijal, Bharat Mani Pokharel

“…Extended-spectrum β-lactamase (ESBL)- and AmpC-β-lactamase-producing Enterobacteriaceae have recently emerged as a public threat in the treatment of nosocomial as well as community-acquired infections. Very little information is currently available about its existence in Nepal. …”
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A human visual cognitive mechanism based network for surface defect detection(基于人类视觉认知机制的表面缺陷检测) by 崔丽莎(CUI Lisha), 代润鹏(DAI Runpeng), 姜晓恒(JIANG Xiaoheng), 李飞蝶(LI Feidie), 陈恩庆(CHEN Enqing), 徐明亮(XU Mingliang)

“…Additionally, the fusion branch introduces the feature preserving downsampling (FPD) module that employs patch merging technique, effectively alleviating the issue of minor defect information loss caused by traditional downsampling. …”
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Design, evaluation, and future projections of the NARCliM2.0 CORDEX-CMIP6 Australasia regional climate ensemble by G. Di Virgilio, G. Di Virgilio, J. P. Evans, J. P. Evans, F. Ji, F. Ji, E. Tam, J. Kala, J. Andrys, C. Thomas, D. Choudhury, C. Rocha, S. White, Y. Li, M. El Rafei, R. Goyal, M. L. Riley, J. Lingala

“…NARCliM2.0 is a valuable resource for assessing climate change impacts on societies and natural systems and informing resilience planning by reducing model biases versus earlier NARCliM generations and providing more up-to-date future climate projections utilising CMIP6.…”
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Retrospective analysis of amantadine response and predictive factors in intensive care unit patients with non-traumatic disorders of consciousness by Corinna Blum, Constanze Single, Kornelia Laichinger, Anna Hofmann, Tim W. Rattay, Tim W. Rattay, Kamaldeen Adeyemi, Reimer Riessen, Michael Haap, Helene Häberle, Ulf Ziemann, Annerose Mengel, Katharina Feil

“…Findings from this study informed the design of our ongoing prospective study, which aims to further evaluate the long-term efficacy of amantadine.…”
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Establishment and validation a relapse prediction model for bipolar disorder by Xiaoqian Zhang, Xiaoqian Zhang, Xiaoqian Zhang, Xiaoqian Zhang, Minghao Wu, Daojin Wang, Long Wang, Long Wang, Long Wang, Wen Xie, Wen Xie, Wen Xie

“…Recurrence risk factors for BD were selected using univariate and binary logistic regression analyses based on the clinical data of the patients and other pertinent information. A nomogram model was developed to predict the incidence of BD relapse. …”
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Integrated analysis of the prevalence and influencing factors of poststroke dysphagia by Xiaopeng Wen, Baochao Fan, Jie Zhan, Hao Wen, Huihui Ban, Yujiao Yang, Chenyang Tao, Cui Li, Kunbin Li, Liming Lu

“…Abstract Objectives Poststroke dysphagia (PSD) is a common complication after stroke but there is limited information on its global prevalence and influencing factors, such as spatial, temporal, demographic characteristics, and stroke-related factors. …”
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Impact of alcohol drinking and tobacco smoking on the drug-resistance of newly diagnosed tuberculosis: a retrospective cohort study in Shandong, China, during 2004–2020 by Yi-Fan Li, Yao Liu, Qi Fu, Wan-mei Song, Jin-yue Liu, Qian-yun Zhang, Ting-ting Xu, Shi-jin Li, Qi-qi An, Si-qi Liu, Huai-chen Li, Ning Ning Tao, Xue-han Zhu, Chun-bao Yu, Jihua Dong

“…Exclusive criteria: retreated cases; extrapulmonary tuberculosis; without information on drug susceptibility testing results, smoking or drinking habits; bacteriological identification as non-tuberculous mycobacteria.Primary and secondary outcome measures Patients were classified into four groups including smokers only (G1), drinker only (G2), smoker +drinker (G3), non-smoker +non-drinker group (G0). …”
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Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y glo... by Mieke Van Hemelrijck, Salvatore Grisanti, Avinash Aujayeb, Martin Forster, Giannis Mountzios, Andrea Napolitano, Bruno Vincenzi, Joachim G J V Aerts, Marina Garassino, Valter Torri, Solange Peters, Alex Friedlaender, Alfredo Addeo, Giuseppe Lo Russo, Roberto Ferrara, Diego Signorelli, Alessandro Russo, So Yeon Kim, Jarushka Naidoo, Scott Gettinger, Heather Wakelee, Martin Sebastian, Mark Awad, Abdul Rafeh Naqash, Alessio Cortellini, Raffaele Giusti, Michele De Tursi, Federica Zoratto, Marco Russano, Rita Chiari, Biagio Ricciuti, Andrea De Giglio, Alain Gelibter, Giuseppe Tonini, Amin H Nassar, Alessandra Curioni-Fontecedro, Eleni Karapanagiotou, Emilio Bria, Jack Bell, Paolo Bironzo, Joao V Alessi, Alessandro Morabito, David J Pinato, Francesco Passiglia, Carlo Genova, Francesca Mazzoni, Alessandro Inno, Francesco Grossi, Luca Cantini, Lorenza Landi, Luigi Della Gravara, Margarita Majem, Uma Mukherjee, Federica Biello, Alessandro Leonetti, Annalisa Guida, Marianna Macerelli, Gabriele Minuti, Giulio Metro, Thomas Newsom-Davis, Eleni Josephides, Andrea Camerini, Elisa Roca, David O’Reilly, Mingjia Li, Laura Mezquita, Teresa Gorría, Claudia A M Fulgenzi, Lauren Young, Joel W Neal, Javier Baena, Francesco Pantano, Jacobo Rogado, Mary Jo Fidler, Teresa Beninato, Federica Pecci, Alessandro Di Federico, Kazuki Takada, Leonardo Brunetti, Talal El Zarif, Laura Moliner, Alberto Servetto, Sukumar Kalvapudi, Sai Yendamuri, Edoardo Garbo, Giuseppina Rita Di Fazio, Monica Loza, Ritujith Jayakrishnan, Michele Montrone, Nichola O Awosika, Bartlomiej Tomasik, Maximilian Rost, Isabelle Monnet, Francesco Agustoni, Artur Katz, Dwight Hall Owen, Michele Ghidini, Armida D’Incecco, Gianpaolo Spinelli, Monica Verrico, Manuel Dupont, Rafael Di Marco Barros, Diego Luigi Cortinovis, Chiara Bennati, Frank Aboubakar Nana, Anne-Marie Dingemans, Taher Abu Hejleh

“…Hierarchical organization indicates ECOG-PS, age and PD-L1-TPS as the most important predictors of 5-year survival, potentially informing clinical practice.…”
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Assessment of Environmental Hazards and Vulnerability of The Rud–E-Shur, Rud-E-Shirin and Rud-E-Minab International Wetland Using the DPSIR Model by Hengameh Safa Eisini, Saber Ghasemi, Afshin Danehkar, Mohsen Dehghani Ghanateghestani, Hossein Parvaresh

“…In order to protect the studied international wetland, it is necessary to promote public information about the ecological characteristics and effects of the wetland in the environment of the province, as well as the threats facing them through public education. …”
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Construction and validation of a risk prediction model for high altitude de-acclimatization syndrome by DING Yu, DING Yu, WANG Zejun, WANG Zejun, XIE Jiaxin, XIE Jiaxin

“…Methods‍　‍Field or online surveys were conducted on the individuals who had ended their high-altitude living and returned to the plain areas from November 2020 to February 2024. Basic information， chronic mountain sickness （CMS）， HADAS symptoms and other data were collected. …”
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Number of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway by Teferi Mekonnen, Vegard Skirbekk, Ekaterina Zotcheva, Bo Engdahl, Bernt Bratsberg, Astanand Jugessur, Catherine Bowen, Geir Selbæk, Hans-Peter Kohler, Jennifer R. Harris, Sarah E. Tom, Steinar Krokstad, Trine Holt Edwin, Yehani Wedatilake, Katrin Wolfova, Dana Kristjansson, Yaakov Stern, Asta Kristine Håberg, Bjørn Heine Strand

“…Further measures were obtained through data linkage between information from Statistics Norway and the HUNT1(1984–86), and HUNT2 (1995–97) Surveys. …”
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Development and application of intelligent auxiliary diagnosis system in the Traditional Chinese Medicine nursing clinic (智能辅诊系统在中医护理门诊中的开发与应用)... by ZHANG Jing (张敬), TANG Ling (唐玲)

“…Intelligent auxiliary diagnosis system constructs in-depth TCM nursing outpatient information system from big data intelligent diagnosis, dominant disease diagnosis and treatment scheme, doctor-patient interaction tracking, and result evaluation and analysis. …”
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Machine learning helps reveal key factors affecting tire wear particulate matter emissions by Zhenyu Jia, Jiawei Yin, Tiange Fang, Zhiwen Jiang, Chongzhi Zhong, Zeping Cao, Lin Wu, Ning Wei, Zhengyu Men, Lei Yang, Qijun Zhang, Hongjun Mao

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Wide-field full-Stokes polarimetry for conical light based on all-dielectric metasurface by Qing Luo, Xiaoshao Ma, Yang Guo, Yang Zhou, Junwei Ma, Weihao Yang, Longjiang Deng, Lei Bi, Jun Qin

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Economic and environmental sustainability of agriculture production at the crop level by A.Z. Bi, K.B. Umesh, B. Md Abdul, D. Sivakumar, P. Srikanth

“…In the present study, a framework was developed that determines the sustainability of a particular crop's output using farm level information.  Micro level indicators of sustainability only for the relevant dimensions of sustainability, viz., economic and environmental sustainability, were compiled and evaluated for their relevance, usefulness, and measurability for agriculture at the crop level. …”
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Pengembangan Aplikasi Sistem Informasi Pendataan Bangunan (SIPBANG) pada Dinas Pekerjaan Umum dan Penataan Ruang (DPUPR) Kota Malang Menggunakan Framework Scrum by Muhamad Rifky, Yusi Tyroni Mursityo, Bondan Sapta Prakoso

“…DPUPR currently has a Building Listing Information System (SIPBANG) to simplify the listing process. …”
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