Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:... by Joachim G J V Aerts, Sjoerd H van der Burg, Martijn P Lolkema, Sai Ping Lau, Freek R van ’t Land, Marjolein Y V Homs, Casper H J van Eijck

“…University Medical Center Rotterdam approved the conduct of the trial. Written informed consent will be required for all participants. …”
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Multidimensional Environmental Drivers of Bamboo Species Richness on Subtropical Islands by Weifeng Zhan, Yanqiu Xie, Xinran Xie, Zujian Chen, Chuanyuan Deng, Hui Huang

“…Understanding the distribution patterns and driving mechanisms of bamboo species diversity on islands is essential for advancing knowledge of island ecosystem processes and informing strategies for bamboo resource conservation and management. …”
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Supra-Annular Versus Intra-Annular Self-Expanding Valves in Small Aortic Annulus: A Propensity Score-Matched Study by Michel Pompeu Sá, MD, MSc, MHBA, PhD, Danial Ahmad, MD, MPH, Yisi Wang, MPH, Floyd Thoma, BS, Amber Makani, MD, Dustin Kliner, MD, Catalin Toma, MD, David West, MD, Derek Serna-Gallegos, MD, Ibrahim Sultan, MD

“…Randomized data are needed to validate these findings and guide informed device selection.…”
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Poor outcome despite modern treatments: A retrospective study of 99 patients with primary and secondary plasma cell leukemia by Camille Tessier, Richard LeBlanc, Jean Roy, Sabrina Trudel, Julie Côté, Marc Lalancette, Jean‐Samuel Boudreault, Émilie Lemieux‐Blanchard, Rayan Kaedbey, Michel Pavic

“…Because of its very low incidence, only a few cohorts have been reported and thus, information on this disease is scarce. The goal of this study was to better understand the clinical features, prognostic factors, and efficacy of modern treatments in both primary PCL (pPCL) and secondary PCL (sPCL). …”
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Ten proposed measures to improve vaccination: Health care providers’ perspectives on promoting the vaccination intake of children with special healthcare needs in China by Xiang Guo, Tianxing Feng, Meiyi Chen, Xuran Zhao, Xiangshi Wang, Yanling Ge, Zhonglin Wang, Zhuoying Huang, Mei Zeng

“…The interview guide explored attitudes towards and suggestions for establishing immunisation advisory clinics and referral networks, updating immunisation guidance documents and vaccine package inserts and strengthening the education of vaccination providers.Results 21 representative healthcare providers were interviewed. 10 measures were proposed to promote routine immunisation for children with special needs: (1) using immunisation advisory clinics to provide vaccination services for CSHCN; (2) establishing a referral network and specifying which cases necessitate referral to advisory clinics; (3) using an interconnected information system to identify, document and follow-up the CSHCN; (4) supporting high-quality clinical research to update immunisation protocols; (5) providing clear and definite immunisation recommendations to parents of eligible CSHCN; (6) seeking immunisation advice from specialised professionals to enhance primary care capability; (7) creating quality improvement programmes; (8) considering immunisation status a mandatory assessment during specialist visits; (9) supporting off-label use of vaccines legally and (10) encouraging pharmaceutical companies to update vaccine package inserts.Conclusion Vaccine uptake among CSHCN in China is suboptimal, highlighting the need for a referral network and a standard immunisation protocol. …”
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Exclusive Breastfeeding Knowledge, Intention to Practice and Predictors among Primiparous Women in Enugu South-East, Nigeria by Chikaodili N. Ihudiebube-Splendor, Chinyelu B. Okafor, Agnes N. Anarado, Nonyelum N. Jisieike-Onuigbo, Anthonia U. Chinweuba, Ada C. Nwaneri, Joyce C. Arinze, Paulina C. Chikeme

“…The Wald statistic in Logistic regression model indicated the coefficient of age (p = 0.026), educational attainment (p = 0.046), EBF knowledge (p = 0.016), and sources of information about EBF (p = 0.027) to be significant predictors of good intention to practise EBF. …”
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Unraveling the threads of depressive symptoms: Enhancing predictions of depression among university junior students by Said El-Ashker, Abdulmajeed Alharbi, Somaya Mahmoud, Feras Al-Awad, Ahlam Alghamdi, Nouf Alaqeel, Mohammed Al-Hariri

“…A self-administered electronic general health and well-being questionnaire was implemented. Written informed consent was obtained from the participants after explaining the study’s purposes. …”
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School-to-work and school-to-university transition and health inequalities among young adults: a scoping review by Matthias Richter, Nico Dragano, Benjamin Wachtler, Stephanie Hoffmann, Max Herke, Katharina Diehl, Marvin Reuter, Paula Mayara Matos Fialho, Maria-Inti Metzendorf, Wiebke Schüttig, Christian Deindl, Sarah Schleberger, Claudia R Pischke

“…Articles in English or German published between 1 January 2000 and 3 February 2020 were considered.Data extraction To collect the main information from the selected studies, a data extraction spreadsheet was created. …”
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The impact of margins and re‐resection in pediatric synovial sarcoma by Andres F. Espinoza, Priya B. Shetty, Jillian C. Jacobson, Hannah Todd, Kelley Harrell, Alfred F. Trappey, John Doski, Eumenia C. Castro, Nicole I. Montgomery, M. Fatih Okcu, Rajkumar Venkatramani, Dai H. Chung, Sanjeev A. Vasudevan

“…Patient and tumor demographics, treatment information, and margin status after surgical resection were collected from the medical record. …”
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Prevalence and Risk Factors Associated with S. haematobium Egg Excretion during the Dry Season, Six Months following Mass Distribution of Praziquantel (PZQ) in 2017 in the Bafia He... by Vicky Daonyle Ndassi, Judith Kuoh Anchang-Kimbi, Irene Ule Ngole Sumbele, Godlove Bunda Wepnje, Helen Kuokuo Kimbi

“…A cross-sectional study including 1001 consenting individuals (aged 3-62 years) was carried out in three localities (Ikata, Bafia, and Munyenge) in the Bafia Health Area between November 2017 and January 2018. Information on sociodemographic, stream usage, and contact behaviour was documented. …”
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Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma by Dengfeng Lu, Fei Wang, Yayi Yang, Aojie Duan, Yubo Ren, Yun Feng, Haiying Teng, Zhouqing Chen, Xiaoou Sun, Zhong Wang

“…Intraoperative glioma samples retained in our unit and the corresponding clinicopathological information were also collected with the patients' knowledge. …”
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EXPERIMENTAL INVESTIGATION OF THE BEHAVIOR OF COLUMN BASE CONNECTIONS WITH CONCENTRICALLY WELDED ANCHOR RODS USING DIGITAL IMAGE CORRELATION METHOD by I. Karami, S.R. Mirghaderi, A.R. Ghiami Azad, M. Ali

“…Digital Image Correlation (DIC) method was used to provide force-displacement diagram and full field strain information of each laboratory sample. DIC is a non-contact and non-destructive technique in which digital images of the point of interest (POI) of a test specimen are captured continuously using a high-resolution camera all through the test. …”
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Next-Generation Sequencing Analysis on Image-Guided Biopsy Samples in Early-Stage Lung Cancer: Feasibility Study and Comparison With Surgical Samples by Louis Gros, MD, Rowena Yip, PhD, MPH, Arel Golombeck, MD, David F. Yankelevitz, MD, Claudia I. Henschke, PhD, MD

“…Introduction: Limited information exists on next-generation sequencing (NGS) success for lung tumors of 30 mm or less. …”
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Seed delivery system in northeastern Democratic Republic of Congo: characteristics, stakeholders mapping and challenges towards building a well-functioning seed system under humani... by Jean M. Mondo, Adrien B. Ndeko, Rodrigue B. Ayagirwe, Henri M. Matiti, Chance Bahati, René M. Civava

“…Results showed that the seed system in the northeastern DRC is mainly informal due to several socioeconomic and technical factors. …”
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Five lessons from a mid-level health manager intervention to increase uptake of tuberculosis prevention therapy in Uganda: ‘it is a completely different thing to implement what you... by Jason Johnson-Peretz, Canice Christian, Cecilia Akatukwasa, Fred Atwine, Elijah Kakande, Moses R. Kamya, Diane V. Havlir, Carol S. Camlin, Gabriel Chamie

“…Methods We performed a thematic analysis of six focus-group discussions from this intervention (held in May 2019, January 2020, September 2021) and 23 key informant interviews with control group participants (between February and August 2019 and September and December 2020). …”
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Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i> by Xiaolan Xu, Chunxia Li, Fangjing Wu, Shuangshuang Zhao, Tiqiang Chen, Haihong You, Yijie Lin, Xiaoxing Zou

“…This study provides useful information about key genes involved in GT biosynthesis, but further exploration and in-depth research are needed to better understand the functions of these genes.…”
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Cross sectional associations of physical activity and sleep with mental health among Chinese university students by Bo Li, Shan-shan Han, Yu-peng Ye, Ya-xing Li, Shu-qiao Meng, Shuo Feng, Han Li, Zhong-lei Cui, Yang-Sheng Zhang, Yao Zhang, Qing Zhang, Guang-xu Wang, Hu Lou, Weidong Zhu, Yang Liu

“…The participants’ PA behaviors, sleep patterns, depressive symptoms (use the CES-D), anxiety symptoms (use the GAD-7), smoking and drinking behaviors, and demographic information were assessed through an online questionnaire using Questionnaire Star software. …”
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An endoscopic ultrasound-based interpretable deep learning model and nomogram for distinguishing pancreatic neuroendocrine tumors from pancreatic cancer by Nan Yi, Shuangyang Mo, Yan Zhang, Qi Jiang, Yingwei Wang, Cheng Huang, Shanyu Qin, Haixing Jiang

“…The optimal DL model was identified and used to establish a clinical signature, which subsequently informed the construction and evaluation of a nomogram. …”
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Prognostic factors for outcomes of idiopathic sudden sensorineural hearing loss: protocol for the SeaSHeL national prospective cohort study by Helen Blackshaw, Anne GM Schilder, Rishi Mandavia, Gerjon Hannink, Muhammad Nayeem Ahmed, Yaami Premakumar, Timothy Shun Man Chu, Tanjinah Ferdous, Nishchay Mehta, Joseph Manjaly, Maha Khan

“…For such trials to be run effectively, reliable information is needed on patients with SSNHL: where they present, numbers, demographics, treatment pathways, as well as outcomes. …”
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Longitudinal changes in factors affecting postoperative patient satisfaction after robot-assisted radical prostatectomy: an assessment using a patient-reported questionnaire by Soichiro Ogawa, Kei Yaginuma, Yuki Harigane, Shunta Makabe, Hitomi Imai, Satoru Meguro, Ryo Tanji, Akifumi Onagi, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Yuichi Sato, Hidenori Akaihata, Masao Kataoka, Motohide Uemura, Yoshiyuki Kojima

“…Our results suggest that giving sufficient information before treatment choice is both important and useful for patients’ decision-making, leading to improved patient QOL.…”
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