Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational... by Yi Guo, Dongyu Zhang, Rafael Meza, Jihyoun Jeon, Dejana Braithwaite, Gerard A Silvestri, Michael K Gould, Jiang Bian, Bruno Hochhegger, Shama D Karanth, Christopher G Slatore, Martin Tammemagi, Mattthew Schabath, Meghann Wheeler, Frederic J Kaye

“…The principal goal of the PLuS study is to characterise the comorbidity burden of individuals undergoing LCS and quantify the benefits and harms of LCS to enable informed decision-making.Methods and analysis PLuS is a multicentre observational study designed to assemble an LCS cohort from the electronic health records of ~40 000 individuals undergoing annual LCS with LDCT from 2016 to 2022. …”
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Bibliometric Analysis of Digital Leadership Studies by Sena Erden Ayhün, İsmail Şimşir, Selma Kılıç Kırılmaz, Erdal Aydın

“…Digital leadership is a leadership model that is focused on innovation and performance which require effective communication and information management competencies. Several recommendations are proposed for researchers, practitioners and policymakers to further develop and implement effective digital leadership strategies. …”
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Hereditary angioedema diagnosis evaluation score (HADES): A new clinical scoring system for predicting hereditary angioedema with C1 inhibitor deficiency by Ricardo Zwiener, MD, Rafael Zamora, MD, Carlos María Galmarini, MD, PhD, Laura Brion, PhD, Laura Arias, MD, Andrea Pino, MD, Paula Rozenfeld, PhD

“…A questionnaire was designed to collect relevant clinical information on possible predictors for HAE. Blood samples were analyzed for C1-INH/C1q levels and C1-INH function. …”
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Prevalence, awareness, treatment, control, and treatment-control rates of hypertension among adults in Hubei province: a cross-sectional survey by Tianjing HE, Lan ZHANG, Shuzhen ZHU, Miaoyan SHEN, Qian LI, Yumeng TANG, Mengge ZHOU, Jingju PAN

“…MethodsBlood pressure measurement and face-to-face interview with the Chinese Adult Chronic Disease and Risk Factor Surveillance Survey Questionnaire were conducted during May – December 2020 among 21 973 adult (≥ 18 years) permanent residents recruited using stratified multistage random cluster sampling at 10 counties/districts/prefectures in Hubei province. The participants′ information on hypertension prevalence, awareness, treatment, and control were collected and analyzed. …”
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The healthfulness of major food brands according to Health Canada’s nutrient profile model for proposed restrictions on food marketing to children by Laura Vergeer, Christine Mulligan, Hayun Jeong, Ayesha Khan, Mary R L’Abbé

“…Design: Nutritional information for products offered by top brands was sourced from the University of Toronto FLIP and Menu-FLIP 2020 databases, respectively. …”
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A new multi-grid bathymetric dataset of the Gulf of Naples (Italy) from complementary multi-beam echo sounders by F. Foglini, M. Rovere, R. Tonielli, G. Castellan, G. Castellan, M. Prampolini, M. Prampolini, F. Budillon, M. Cuffaro, G. Di Martino, V. Grande, S. Innangi, M. F. Loreto, L. Langone, F. Madricardo, A. Mercorella, P. Montagna, C. Palmiotto, C. Pellegrini, A. Petrizzo, L. Petracchini, A. Remia, M. Sacchi, D. Sanchez Galvez, A. N. Tassetti, F. Trincardi

“…<p>High-resolution bathymetry provides critical information to marine geoscientists. Bathymetric big data help characterise the seafloor and its benthic habitats, understand sedimentary records, and support the development of offshore engineering infrastructures. …”
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Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) by Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun

“…The microfilament cytoskeleton, formed by the process of actin polymerization, serves not only to support the morphology of the cell, but also to regulate a number of cellular activities. …”
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Effect of intramuscular midazolam premedication on patient satisfaction in women undergoing general anaesthesia: a randomised control trial by Kwang Ho Lee, Seung Woo Song, Younghyun Jin, Hyunjae Lim, Jonghoon Lee

“…A subgroup analysis revealed that this difference was greater in patients with anxiety, defined as those whose Amsterdam Preoperative Anxiety and Information Scale anxiety score was ≥11, than that for the whole sample population (percentage difference: 24.0%, OR 4.33, 95% CI 1.25 to 14.96). …”
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TRENDS IN HIGHER VOCATIONAL EDUCATION: PROFESSIONALIZATION OR DEPROFESSIONALIZATION? by Yu. R. Vishnevsky, D. Yu. Narkhov, Ya. V. Didkovskaya

“…Student population is the most important social resource of development of post-industrial information society. Therefore, those students will take places of leading experts and will define the level of social and economic wellbeing of the country and its competitiveness in the world in the near future. …”
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Genetic markers of children asthma: predisposition to disease course variants by M. V. Smolnikova, Ed. W. Kasparov, M. A. Malinchik, K. V. Kopylova

“…Polymorphic genes of inflammatory mediators, including cytokines, play an important role in developing various disease forms. In the current study, large-scale original data on the prevalence of cytokine gene genotypes (IL2, IL4, IL5, IL6, IL10, IL12, IL13, IL17A, IL31, IL33, IFNG, TNFA) among Russian children with asthma in Krasnoyarsk region have been obtained. …”
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Forecasting Weather using Deep Learning from the Meteorological Stations Data : A Study of Different Meteorological Stations in Kaski District, Nepal by Supath Dhital, Kapil Lamsal, Sulav Shrestha, Umesh Bhurtyal

“…In Nepal, the Department of Hydrology and Meteorological uses a numerical modeling approach to forecast the weather, which is tardy and requires high-end equipment to process the information, so a deep learning approach will be the best alternative. …”
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Spatial-temporal analysis of carbon benefit and land use for low-carbon development strategies in Shandong Province, China by Hui Wen, Ziyu Zhong, Xujie Kong, Jichun Wang, Renqiang Li, Zhaosheng Wang, Shulin Yu, Zhen Xu, Hexin Chen, Qi Zhu, Pan Wang, Jiaquan Duan, Yan Ren

“…The CBI analysis and classification of the 16 cities into four categories highlights the spatial-temporal heterogeneous of the carbon efficiency, and diverse roles cities play in the province’s overall carbon balance, informing city-specific, targeted carbon reduction strategies. …”
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The epidemiology and clinical presentation of seropositive neuromyelitis optica spectrum disorder in a US population by Aaron M. Carlson, Carlos E.V. Sollero, Andrew B. Wolf, Stefan Sillau, Barrie L. Schmitt, Kelli M. Money, Kavita V. Nair, Amanda L. Piquet, Jeffrey L. Bennett

“…Methods We completed a retrospective observational study of adult patients in the University of Colorado Health System from 1 January 2011 to 31 December 2020, using Health Data Compass (HDC), a data warehouse that combines electronic health information with claims and public health data in Colorado. …”
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Amputations of Lower Limb in Subjects with Diabetes Mellitus: Reasons and 30-Day Mortality by Magdalena Walicka, Marta Raczyńska, Karolina Marcinkowska, Iga Lisicka, Arthur Czaicki, Waldemar Wierzba, Edward Franek

“…Datasets of the National Heath Fund containing information about all services within the public healthcare system in Poland, spanning the years 2010-2019, were analyzed. …”
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Online tools to predict individualised survival for primary oesophageal cancer patients with and without pathological complete response after neoadjuvant therapy followed by oesoph... by Jie Zhang, Xiang Chen, Dong Dong, Lijie Tan, Yajie Zhang, Hecheng Li, Yuqin Cao, Binhao Huang, Han Tang, Tianzheng Shen, Xijia Feng, Jiahao Zhang, Liqiang Shi, Chengqiang Li, Heng Jiao

“…Key predictors included demographic characteristics, pretreatment clinical stage, surgical approach, pathological information and postoperative treatments. The predictive models for pCR and non-pCR patients demonstrated good calibration and clinical utility, with acceptable discrimination that surpassed that of the current tumour, node, metastases staging system.Conclusions The web-based dynamic nomograms for pCR (https://predict-survival.shinyapps.io/pCR-eso/) and non-pCR patients (https://predict-survival.shinyapps.io/non-pCR-eso/) developed in this study can facilitate the calculation of OS probability for individual patients undergoing neoadjuvant therapy and radical oesophagectomy, aiding clinicians and patients in making personalised treatment decisions.…”
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Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population by Erich Batzella, Joaquin Gutierrez de Rubalcava Doblas, Gloria Porcu, Silvia Bressan, Elisa Barbieri, Carlo Giaquinto, Anna Cantarutti, Cristina Canova

“…This retrospective cohort study utilized data from the PEDIANET registry, containing sociodemographic, clinical, and prescribing information on patients assisted by Italian family pediatricians, linked to the corresponding area deprivation index. 29,576 children with at least 10 years of follow-up, born at term with normal birthweight, and at least three plausible BMI measurements were identified. …”
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Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…This study investigates the 800 mg threshold by using a prospectively collected database of patient information.Design A retrospective cohort study: (Part I) cross-sectional, (Part II) longitudinal.Setting and participants PD patients at a Movement Disorders Center in a large academic, tertiary medical setting.Outcome measures An analysis was performed using carbidopa/levodopa at dosages below and above the 800 mg threshold. …”
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Perspectives on adapting a mobile application for pain self-management in neurofibromatosis type 1: results of online focus group discussions with individuals living with neurofibr... by Chitra Lalloo, Lauretta E Grau, Kaitlyn Larkin, Jennifer N Stinson, William T Zempsky, Samuel A Ball, Frank D Buono

“…The NF1 group appeared interested in detailed and nuanced pain tracking capabilities; the expert group prioritised tracking information such as mood, nutrition and activity to identify potential associations with pain. …”
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Index-based livestock insurance schemes to manage climate risks in Ethiopia: determinants of farmer’s willingness to pay and lessons learned from Dasenech district, South Omo by Tagesse Melketo, Degefa Tolossa, Meskerem Abi, Sisay Bedeke, Tenaw Fentaw

“…The study also used key informant interviews and focus group discussions to collect qualitative data. …”
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Elucidating genetic variability between randomly bred domestic cats and Persian domestic cats from different geographical locations using microsatellite markers by Shirin Mahmoodi, Ali Hojabr Rajeoni, Mehrshad Zeinolabedini, Arash Javanmard, Mohammad Hossein Banabazi

“…It is critical to conserve these species and prevent inbreeding from reducing their genetic diversity by understanding their genetic relationships and applying the information to breeding management. The diverse population was an excellent choice for studying genetic diversity and inbreeding phenomena. …”
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