Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning by D. E. Ivanoshchuk, A. B. Kolker, O. V. Timoshchenko, S. E. Semaev, E. V. Shakhtshneider

“…A negative result of genetic screening for pathogenic variants in genes of the low-density lipoprotein receptor and its ligands does not rule out a diagnosis of familial hypercholesterolemia. …”
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Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.) by Federico Giletti

“…It can therefore be said that, just as the Archaic and Early and Middle Hellenistic city received and reworked in its architecture and urban planning knowledge, practice and models taken from both Etruscan-Italic and Greek sources, Pompeii also implemented techniques and devices for water collection and conservation that were clearly derived from the mix of knowledge and engineering practices in use in the most important civilisations evidenced between the Archaic and Early Hellenistic periods in the Tyrrhenian area.With regard to water catchment wells, which may have already been in use in the Archaic age, but were certainly widespread and used in the Samnite city at least until the advent of aqueduct dependent water supplies, it is also possible to trace their historical evolution, which follows the urban development of Pompeii over time.Contrary to the oldest forms of water storage, which seem to have a continuity of use and in some cases coexist with the later chambered cisterns, wells seem gradually to have lost their original function, especially those associated with production contexts or located along minor roads. …”
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Human-genome single nucleotide polymorphisms affecting transcription factor binding and their role in pathogenesis by E. V. Antontseva, A. O. Degtyareva, E. E. Korbolina, I. S. Damarov, T. I. Merkulova

“…The vast majority of SNPs identified in the human genome do not have any effect on the phenotype; however, some can lead to changes in the function of a gene or the level of its expression. Most SNPs associated with certain traits or pathologies are mapped to regulatory regions of the genome and affect gene expression by changing transcription factor binding sites. …”
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins by Maria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, Iqbal Mahmud, Yue Lu, Ailing Huang, Lisa K. Duong, Qi Wang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Bo Wei, Wai-Kin Chan, Kevin Lin, Jie Zhang, Efrosini Tsouko, Shonik Ganjoo, Hampartsoum B. Barsoumian, Thomas S. Riad, Yun Hu, Carola Leuschner, Nahum Puebla-Osorio, Jing Wang, Jian Hu, Michael A. Davies, Vinay K. Puduvalli, Cyrielle Billon, Thomas P. Burris, Philip L. Lorenzi, Boyi Gan, James W. Welsh

“…Methods included mass spectrometry-based lipidomics, targeted lipidomics, Oil Red O staining, Seahorse analysis, quantitative PCR, immunohistochemistry, PPARγ transcription factor assays, ChIP-seq, untargeted lipidomic analysis, ROS assay, ex vivo co-culture of CD8+ T cells with cancer cells, ATAC-seq, RNA-seq, Western blotting, co-immunoprecipitation assay, flow cytometry and Imaging Mass Cytometry. …”
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Interior Peak Solutions for a Semilinear Dirichlet Problem by Hissah Alharbi, Hibah Alkhuzayyim, Mohamed Ben Ayed, Khalil El Mehdi

“…The proof of our results relies on precise expansions of the gradient of the Euler–Lagrange functional associated with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>(</mo><msub><mi mathvariant="script">P</mi><mi>ε</mi></msub><mo>)</mo></mrow></semantics></math></inline-formula>, along with a suitable projection of the bubbles. This projection and its associated estimates are new and play a crucial role in tackling such types of problems.…”
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PENGARUH FASAD MASJID RAYA TERHADAP ARSITEKTUR MASJID-MASJID KECIL DI MAKASSAR by Wahyuni Jaharuddin, Ria Wikantari R, Afifah Harisah

“…Sampel penelitian terdiri atas Masjid Raya dan 4 (empat) masjid kecil di Makassar yaitu, Masjid Jendral Sudirman, Masjid Pondok Pesantren Nahdatul Qurra’a Walhuffadz, Masjid Shihatul Iman dan Masjid Lantja Abduh Massi yang dipilih secara teknik purposive sampling. …”
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Redistribución espacial y migración interna de la población en Chile en los últimos 35 años (1965-2002): una síntesis de las hipótesis y la evidencia by Daniela González Ollino, Jorge Rodríguez Vignoli

“…Los datos sugieren  que efectivamente en la segunda mitad del decenio de 1990 la Región Metropolitana y el amgs mostraron la novedosa condición de zonas de emigración neta, pero que paradójicamente esto no alcanza para revertir el incremento de la concentración de la población nacional en ellas por el efecto combinado de un crecimiento natural sobre la media y una fuerte absorción de inmigrantes internacionales. …”
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Les techniques de construction du second forum de Bavay (Nord) : utilisation, origine et datation des matériaux en terre cuite by Xavier Deru, Christine Louvion

“…The bricks present artisans’ trademarks; 437 specimens were recorded for 35 types, with ATAB, ATIL, CVS, FAL, HAMSIT or TRPS being the most frequent. …”
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Implementasi Simple Additive Weight pada Sistem Pendukung Keputusan Penerima Bantuan Stimulan Perumahan Swadaya Berbasis Web di Dinas Perumahan dan Kawasan Pemukiman Kota Magelang by Eko Joko Pamungkas, Uky Yudatama, Emilya Ully Artha

“…Adapun kriteria yang harus dipenuhi untuk mendapatkan Bantuan Stimulan Perumahan Swadaya ini Kondisi Atap, Dinding, Pintu & Jendela, Lantai, Pondasi,Sanitasi, dan calon penerima harus merupakan warga negara Indonesia dan mempunyai sertifikat hak milik atas tanah rumah tersebut. …”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

“…Unfortunately, nothing is known about its immediate environment. To the west of the oppidum sector 4 (Saint-Pierre fountain) corresponds to another tapping of a source, modified several times. …”
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The role of skill and expertise and organizational resources along with the relevant components in the competitive environment of the organization (case study: Tehran Province Muni... by Mehdi Aghighi, Rashid Zolfegari Zaferani, Behzad Mashali

“…The results of this research corresponds with the results of SUKRESNA et al, (2021), Azila-Gbettor et al, (2021), Aghighi et al, (2020), Alfawaire & Atan (2021), Motiei et al, (2021), and Emeagwal & Ogbonmwan (2018). …”
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Modeling the relationship between the moral charter derived from Islamic teachings and performance with the mediating variable of employees' perception by leila jahantigh, Abbas Babaeenezhad, Mohsen Zayandehroudi, saeed sayadi

“…The results showed that there is a significant positive relationship between work ethic and its dimensions with the job performance of employees. …”
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