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  1. 68581

    Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

    Published 2025-02-01
    “…Dampening the downstream effects of a high concentration of α-defensins may render AAT and TLR4 inhibitors as potential therapies to decrease NTHi colonization and increase its clearance by phagocytosis in AATD individuals.…”
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  2. 68582

    Therapeutic Potential of <i>Cajanus cajan</i> (L.) <i>Millsp</i>. Leaf Extract in Modulating Gut Microbiota and Immune Response for the Treatment of Inflammatory Bowel Disease by Mingzhang Lin, Linghua Piao, Zhendong Zhao, Li Liao, Dayong Wang, Haiwen Zhang, Xiande Liu

    Published 2025-01-01
    “…</i>, traditionally used in Chinese herbal medicine for gastrointestinal issues such as bleeding and dysentery, has garnered attention for its potential therapeutic benefits. However, its effects on IBD remain largely unexplored. …”
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  3. 68583

    Application of chemotactic behavior for life detection by Max Riekeles, Vincent Bruder, Vincent Bruder, Nicholas Adams, Berke Santos, Berke Santos, Dirk Schulze-Makuch, Dirk Schulze-Makuch, Dirk Schulze-Makuch

    Published 2025-02-01
    “…One excellent biosignature for the present detection of microbial life on Earth is motility, leading to its growing interest within the astrobiological community as an observable attribute that, if detected during future in situ space missions, could point towards the existence of life on Mars or other celestial bodies. …”
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  4. 68584

    Unraveling TGF-β1’s Role in Mediating Fibrosis and Cell Death in Feline Kidney Cells by Chanyanuch Intachat, Phongsakorn Chuammitri, Benjaporn Sornpet, Prapas Patchanee, Nawin Manachai, Kakanang Piyarungsri

    Published 2025-01-01
    “…The MAPK pathway regulates the Bcl-2 protein family, which is known for its anti-apoptosis properties. This study aimed to quantify the mRNA expression of the <i>TGFβ</i>, <i>MAPK</i>, and <i>Bcl2</i> genes and the protein expression of TGF-β1 and MAPK in feline kidney cells and tissue. …”
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  5. 68585

    Coping with Stress During the COVID-19 Pandemic: Resilience and Mental Health Among Latino Day Laborers by Sylvia A. Ayieko, John Atkinson, Anna Llamas, Maria E. Fernandez-Esquer

    Published 2024-12-01
    “…The implications of this study include the need to further investigate the use of negatively worded items and how resilience is demonstrated among other vulnerable populations or cultural groups.…”
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  6. 68586

    Demonstration of sizing nursing staff methods in intensive care by Érica Batassini, João Lucas Campos de Oliveira, Mariur Gomes Beghetto

    Published 2025-01-01
    “… Objective: to demonstrate the sizing of intensive care nursing staff estimated by two calculations, using the Nursing Activities Score as one of its central components. Method: descriptive, retrospective study that compiled the Nursing Activities Score scores of patients in five Intensive Care Units of a hospital in southern Brazil. …”
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  7. 68587

    Community Perception on Beekeeping Practices, Management, and Constraints in Termaber and Basona Werena Districts, Central Ethiopia by Abadi Berhe, Abebe Asale, Delenasaw Yewhalaw

    Published 2016-01-01
    “…Adequate forage availability coupled with favorable and diversified agroclimatic conditions of Ethiopia creates environmental conditions conducive to the growth of over 7000 species of flowering plants which have supported the existence of large number of bee colonies in the country. Despite its potential of honey production, the contribution of apiculture to state GDP is far below its expectation and not well estimated yet. …”
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  8. 68588

    <i>pathways-ensemble-analysis</i> v1.1.0: an open-source library for systematic and robust analysis of pathway ensembles by L. Welder, N. Grant, M. J. Gidden, M. J. Gidden

    Published 2025-01-01
    “…We introduce a new open-source package, <i>pathways-ensemble-analysis</i>, which provides an object-oriented framework for the key steps in analysis, describing its structure and providing an illustrative example of its use. …”
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  9. 68589

    Long-Term Oncological Outcomes Related to Lymphadenectomy in Clinical Stage I NSCLC: A Multicenter Retrospective Experience by Beatrice Manfredini, Carmelina Cristina Zirafa, Alessandro Stefani, Gaetano Romano, Greta Alì, Riccardo Morganti, Ilaria Ceccarelli, Federico Davini, Pier Luigi Filosso, Franca Melfi

    Published 2025-01-01
    “…Background: Lymphadenectomy is considered a key part of the radical treatment of resectable lung cancer, although its appropriate extension in early stages is a debated topic due to the great heterogeneity of studies in the literature. …”
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  10. 68590

    Harnessing Human-Centered Design for Evidence-Based Psychosocial Interventions and Implementation Strategies in Community Settings: Protocol for Redesign to Improve Usability, Enga... by Aaron R Lyon, Sean A Munson, Michael D Pullmann, Brittany Mosser, Tricia Aung, John Fortney, Alex Dopp, Katie P Osterhage, Helen G Haile, Kathryn E Bruzios, Brittany E Blanchard, Ryan Allred, Macey R Fuller, Patrick J Raue, Ian Bennett, Jill Locke, Karen Bearss, Denise Walker, Elizabeth Connors, Eric Bruns, Jenna Van Draanen, Doyanne Darnell, Patricia A Areán

    Published 2025-01-01
    “…The Center’s second round of funding (2023-2028) focuses on using the Discover, Design and Build, and Test (DDBT) framework to address 3 priority clinical intervention and implementation strategy mechanisms (ie, usability, engagement, and appropriateness), which we identified as challenges to implementation and scalability during the first iteration of the center. Local redesign teams work collaboratively and share decision-making to carry out DDBT. …”
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  11. 68591

    Enriching Wheat Bread With Banana Peel Powder: Impact on Nutritional Attributes, Bioactive Compounds, and Antioxidant Activity by Most. Jesmin Akhter, Md. Al-Amin, Md Akram Hossain, Md. Murtuza Kamal

    Published 2024-01-01
    “…In summary, the incorporation of BPP significantly influenced various aspects of bread, highlighting its potential for applications in the food and industry sectors.…”
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  12. 68592

    Optimasi Weight AHP Menggunakan Genetic Algorithm untuk Rekomendasi Platform Media Sosial Sebagai Sarana Promosi Digital by Risqy Siwi Pradini, Mochammad Anshori, M. Syauqi Haris

    Published 2024-10-01
    “…Selain itu, semakin banyaknya jumlah generasi maka proses evolusi akan semakin sering terjadi. …”
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  13. 68593

    Ethics Underpinning Data Policy in Crisis Situations by Perihan Elif Ekmekci, Lili Zhang, Francis P. Crawley

    Published 2025-01-01
    “…In pursuing resilient societal ecosystems, crisis data management should consider ethical governance throughout its full lifecycle. The UNESCO Recommendation on Open Sciences paved the way for ethical considerations in crisis data policies by internationally defined shared values and principles for Open Science. …”
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  14. 68594

    From threat to response: Cybersecurity evolution in Albania by Klorenta PASHAJ, Vilma TOMÇO, Eralda GJIKA

    Published 2025-01-01
    “… As Albania's digital landscape expands, its vulnerability to sophisticated cyber threats increases correspondingly. …”
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  15. 68595

    Assessing Driving Risk Level: Harnessing Deep Learning Hybrid Model With Intercity Bus Naturalistic Driving Data by Wei-Hsun Lee, Che-Yu Chang

    Published 2025-01-01
    “…The model&#x2019;s effectiveness is highlighted by its outstanding weighted average F1-score of 0.932, indicating exceptional robustness and predictive accuracy. …”
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  16. 68596

    Enzymatic Activity Analysis and Catalytic Essential Residues Identification of Brucella abortus Malate Dehydrogenase by Xiangan Han, Yongliang Tong, Mingxing Tian, Yuxi Zhang, Xiaoqing Sun, Shaohui Wang, Xusheng Qiu, Chan Ding, Shengqing Yu

    Published 2014-01-01
    “…In this study, the recombinant MDH protein (His-MDH) of Brucella abortus was purified and its ability to catalyze the conversion of oxaloacetate (OAA) to L-malate (hereon referred to as MDH activity) was analyzed. …”
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  17. 68597

    Work engagement, resilience and turnover intentions among nurses: a mediation analysis by Collins Atta Poku, Jonathan Bayuo, Veronica Adwoa Agyare, Nana Kobi Sarkodie, Victoria Bam

    Published 2025-01-01
    “…This is because it not only interrupts continuity of service but also its financial implications. Aim The purpose of the study was to find out the effects of work engagement on nurses' intentions to leave their jobs while considering resilience as a mediating factor. …”
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  18. 68598
  19. 68599
  20. 68600

    Mathematical Model of an Open Area of Space Sensor by A. A. Jezhora, Y. A. Zavatski, A. V. Kovalenko, A. M. Naumenko

    Published 2020-03-01
    “…The purpose of the work was to build a mathematical model of a sensor with an open area of space and calculate its parameters.Results of main parameters calculations of the open space sensor are presented. …”
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