A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation by Rodolfo Moreno-Fuquen, Juan F. Avellaneda-Tamayo, Kevin Arango-Daraviña, Javier Ellena, Alan R. Kennedy

“…Molecular docking studies demonstrate strong binding affinity to the ABL1 enzyme, with PAPP1 showing comparable binding energy to imatinib, indicating its potential as a lead compound for further development. …”
Get full text

Status of sleeping habits and its influence on growth and metabolism of children in Beijing: a population-based cross-sectional study by Yiren Chen, Lijun Wu, Zijun Liao, Yiying Huang, Qin Liu, Shaoli Li, Junting Liu, Xinnan Zong, Jun Tai, Fangfang Chen

Get full text

RP-HPLC Method for the Determination of Cinitapride in the Presence of its Degradation Products in Bulk Drug by S. M. N. Roy, Kiran V. Mangaonkar, A. Y. Desai, Santosh M. Yetal

“…The method was validated by determining its specificity, linearity, precision and accuracy. …”
Get full text

A Water Balance Model Based on Budyko Framework and Its Calibration through Particle Swarm Optimization Algorithm by Umut Okkan, Umut Kırdemir

Get full text

Experimental Research on the Similarity of Rime Icing on a Cylinder Rotating around Its Horizontal Axis by Lei Shi, Yan Li, Wenfeng Guo, Ce Sun

Get full text

Mathematical Simulation of Lost Circulation in Fracture and Its Control by Xiao Cai, Boyun Guo, Qingfeng Guo, Hongwei Jiang

“…The nature of lost circulation and its control is not yet fully understood. A method to characterize the mud loss in fracture and the plugging process of lost circulation materials is highly desired to obtain a thorough understanding of mud losses in fracture and provide reference for lost circulation control. …”
Get full text

Metabolic Syndrome and Its Associated Factors among Type 2 Diabetic Patients in Southwest Ethiopia, 2021/2022 by Dereje Gemeda, Endegena Abebe, Abdissa Duguma

“…This study is aimed at assessing metabolic syndrome and its associated factors among patients with type 2 diabetes attending chronic follow-up units at hospitals in Southwest Ethiopia, in 2020. …”
Get full text

SOR-Like New Iterative Method for Solving the Epidemic Model and the Prey and Predator Problem by Atika Radid, Karim Rhofir

“…Our aim in this paper is to propose an SOR-like new iterative method by introducing a relaxation parameter ω to improve the new iterative method proposed by Daftardar-Gejji and Jafari (NIM) [J. …”
Get full text

Exclusion Limits on a Scalar Decaying to Photons and Distinguishing Its Production Mechanisms by Tanumoy Mandal

“…If a new scalar is discovered at the LHC, it would be very important to identify its production mechanism in order to probe the nature of the underlying theory. …”
Get full text

Cardiovascular Hyperreactivity and its Association with Cardiovascular Risk Factors by Milagros Lisset León Regal, Mikhail Benet Rodríguez, Yudith Brito Pérez de Corcho, Lázaro Hermes González Otero, José Omar de Armas García, Luciano Miranda Alvarado

Get full text

Efficacy of Chlorogenic Acid in Treating Tripterygium Glycoside-Induced Asthenozoospermia in Rats and Its Possible Mechanisms by Long Chen, God’spower Bello-Onaghise, Mo Chen, Shunda Li, Yu Zhang, Haoran Wang, Qianwei Qu, Yanhua Li

Get full text

Microbiological Quality Assessment by PCR and Its Antibiotic Susceptibility in Mangrove Crabs (Ucides cordatus) from Guanabara Bay, Rio de Janeiro, Brazil by M. C. N. Carvalho, M. M. Jayme, G. S. Arenazio, F. V. Araújo, S. G. F. Leite, E. M. Del Aguila

“…Vibrio strains from Piedade, Itaóca, and Suruí showed 86%, 78%, and 85% resistance, respectively, to ampicillin. …”
Get full text

Health-Related Quality of Life and Its Influencing Factors in Patients with Hepatitis B: A Cross-Sectional Assessment in Southeastern China by Ping Chen, Fen Zhang, Yiqun Shen, Yubo Cai, Chaolei Jin, Yan Li, Mingmin Tu, Weizhen Zhang, Yu Wang, Shi-Feng Zhang, Jiangyun Wang, Lanjuan Li

Get full text

Non-histone lactylation: unveiling its functional significance by Pusong Shi, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang

“…Lactylation of histones was initially identified, and subsequent studies have increasingly demonstrated its widespread presence on non-histone proteins. …”
Get full text

Prevalence of Bovine Trypanosomosis and Its Associated Risk Factor in Hawa Galan District, Kelem Wollega Zone of Ethiopia by Girma Tsegaye, Belay Abebe, Geremew Haile

“…So, effective control methods could be applied to decrease the disease and its related economic loss.…”
Get full text

Pore Structure Characteristics, Genesis, and Its Controlling Effect on Gas Migration of Quaternary Mudstone Reservoir in Qaidam Basin by Shijie He, Xianglu Tang, Zeyu Shao, Zhenxue Jiang, Bo Wang, Xiaoxue Liu, Yuchao Wang, Mingli Xu

Get full text

Iterates of Volterra operators and indeterminate forms by Pablo Braz e Silva, Andrés R. R. Papa

“…We state and prove a theorem showing how iterates of the Volterra operator can be used to evaluate indeterminate forms of type 0/0. …”
Get full text

FARMER-HERDERS CONFLICTS IN NIGERIA: ITS CHALLENGES AND INTERVENTIONS by M.O. Mazeli, Binta Side

“…This issue is key to resource sustainability in Nigeria as the majority of its citizens require land for farming and grazing. …”
Get full text

Thesis Overview: Oscillating wave surge converters – Large eddy simulation modelling of wave farms hydrodynamics and its related energy potential by Guilherme Fuhrmeister Vargas, Alexandre Beluco

“…This technology, which is on a pre-commercial development scale, presents one of the greatest potentials for electricity generation, due to its operating principle and the great improvement in design experienced over the last few years. …”
Get full text

The Incidence of Depression among the Population of Central Kazakhstan and Its Relationship with Sociodemographic Characteristics by L. Turgunova, Ye Laryushina, A. Turmukhambetova, B. Koichubekov, M. Sorokina, I. Korshukov

Get full text