Metabolic stability and its role in the discovery of new chemical entities by Słoczyńska Karolina, Gunia-Krzyżak Agnieszka, Koczurkiewicz Paulina, Wójcik-Pszczoła Katarzyna, Żelaszczyk Dorota, Popiół Justyna, Pękala Elżbieta

“…In the present paper, issues of compound metabolic stability will be discussed, with special emphasis on its significance, in vitro metabolic stability testing, dilemmas regarding in vitro-in vivo extrapolation of the results and some aspects relating to different preclinical species used in in vitro metabolic stability assessment of compounds.…”
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Application and Validation of Simple Isocratic HPLC-UV-DAD Method with Dual Wavelength Detection for Ivabradine Determination and Its Application in the Study of Stress Degradation by Joanna Nowakowska, Piotr Pikul, Marcin Marszałł, Krzesimir Ciura

“…Due to the chemical nature of ivabradine, which absorbs light at 207 nm and 286 nm, its detection was performed at two wavelengths. …”
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Credit Rating Model of Small Enterprises Based on Optimal Discriminant Ability and Its Empirical Study by Zhanjiang Li, Lin Guo

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Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm by Aiji Sakamoto, Masaaki Kawashiri, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Masakazu Yamagishi

“…We examined the expression of ephrin-B1 and its cognate receptor EphB2, key regulators of angiogenesis and embryogenesis, in human abdominal aortic aneurysm (AAA) and analyzed their functional roles in cell migration. …”
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Bernardi Integral Operator and Its Application to the Fourth Hankel Determinant by Abid Khan, Mirajul Haq, Luminiţa-Ioana Cotîrlă, Georgia Irina Oros

“…In recent years, the theory of operators got the attention of many authors due to its applications in different fields of sciences and engineering. …”
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Burden of diabetic ketoacidosis and its predictors among diabetic patients in Ethiopia: Systematic review and meta-analysis. by Sefineh Fenta Feleke, Anteneh Mengist Dessie, Zenebe Daniel Getachew, Fasikaw Kebede Bizuneh, Atitegeb Abera Kidie, Berihun Mulu Yayeh, Birtukan Gizachew Ayal, Natnael Amare Tesfa

“…The overall pooled prevalence of diabetic ketoacidosis and its components was estimated using a random effects model. …”
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Modelo de categorização de empresas hoteleiras familiares e ciclo de vida: um estudo nas cidades de Itapema e Porto Belo/SC/Brasil by Juarez Prado Córdova, Anete Alberton

“…Participaram da amostra 94,12% empresas familiares (47 meios de hospedagem) de Itapema e Porto Belo/SC/Brasil. Como resultados da pesquisa, cinco tipos de empresas hoteleiras familiares foram identificados, considerando o modelo de Westhead & Howorth (2007), e identificadas relações positivas entre as categorias de empresas familiares com o ciclo de vida e funções de gestão. …”
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A Rapid and Selective LC-MS/MS Method for Quantification of Quetiapine in Human Plasma and its Application to Pharmacokinetic Study on Indian Schizophrenia Patients by S. Ravinder, A. T. Bapuji, K. Mukkanti, M. Nagesh, H. L. V. Ravikiran

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Gut Microbiota and its Metabolites in Pathogenesis of NAFLD by M. S. Reshetova, O. Yu. Zolnikova, V. T. Ivashkin, K. V. Ivashkin, S. A. Appolonova, T. L. Lapina

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The Effort to Rationalize Antibiotic Use in Indonesian Hospitals: Practice and Its Implication by Selma Siahaan, Rukmini Rukmini, Betty Roosihermiatie, Pramita Andarwati, Rini S. Handayani, Ingan U. Tarigan, Tita Rosita, Rustika Rustika, Yuslely Usman, Lusi Kristiana

“…Though hospital leadership and its commitment to implementing AMR-CP are favorable, there is room for improvement. …”
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Technological and environmental design: Italy and Greece in comparison by Antonella Violano, Alexandra Sotiropoulou, Ioannis Tzouvadakis, Euphrosyne Triantis, Athanasios Stamos, Antonio Bosco

“…As an answer to new challenges concerning the role of the architect in future societies, a new approach to the teaching of the technological and environmental design was developed by an interdisciplinary team of academics, involving a reconsideration of the basic concepts and strategies in architectural design and its interaction both with the natural and built environment and users. …”
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Spatio-temporal behavior of atmospheriC concentration of NO2 using OMI sensor and its effect on precipitation in Iran by abolhassan gheibi, ali soleymani, hossein malakooti

“…The aim of this study is to examine the concentration and trends of nitrogen dioxide pollution between 2005 and 2018, and explore its association with precipitation levels in the region. …”
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Partitioned Quasi-Newton Approximation for Direct Collocation Methods and Its Application to the Fuel-Optimal Control of a Diesel Engine by Jonas Asprion, Oscar Chinellato, Lino Guzzella

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Crystal growth principles, methods, properties of silicon carbide and its new process prepared from silicon cutting waste by Shengqian Zhang, Yongsheng Ren, Xingwei Yang, Wenhui Ma, Hui Chen, Guoqiang Lv, Yun Lei, Yi Zeng, Zhengxing Wang, Bingxi Yu

“…The third-generation semiconductor silicon carbide (SiC) has attracted widespread attention due to its excellent properties, such as high thermal conductivity, large bandgap, high breakdown field strength, and high saturation electronic drift rate, etc. …”
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The Effects of Urban Pollution on the “Gesù Nuovo” Façade (Naples, Italy): A Diagnostic Overview by Alessandro De Rosa, Paola Cennamo, Chiara Saltarelli, Giorgio Trojsi, Juri Rimauro, Maria Rosaria Vigorito, Elena Chianese

“…The aims of this study were to investigate the extent of these phenomena on the decorative apparatus of the frontal façade of Gesù Nuovo Church, in the historical centre of Naples (Italy). Preliminary diagnostics consisted of XRD and FTIR to analyse the composition of stone materials and inquire about previous restorations. …”
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Dramatic Autobiography: the Poetic Voice Recreating Itself in Dante Gabriel Rossetti’s ‘The Bride’s Prelude’ by Raphaël Rigal

“…As such, this poetic form helps recreate a life, through the fictitious reality of the poetic voice: by talking about itself and primarily to itself, the poetic persona of the dramatic monologue builds up an imaginary autobiography. …”
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Long-term safety and sustained efficacy of bimekizumab in patients with ankylosing spondylitis (radiographic axial spondyloarthritis): 5-year results from BE AGILE (phase 2b) and its open-label extension by Sofia Ramiro, Désirée van der Heijde, Atul Deodhar, Xenofon Baraliakos, Denis Poddubnyy, Lianne S Gensler, Helena Marzo-Ortega, Natasha de Peyrecave, Victoria Navarro-Compán, Tetsuya Tomita, Carmen Fleurinck, Ute Massow, Thomas Vaux

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A Review on Pineapple Leaves Fibre and Its Composites by M. Asim, Khalina Abdan, M. Jawaid, M. Nasir, Zahra Dashtizadeh, M. R. Ishak, M. Enamul Hoque

“…Furthermore, it summarizes the recent work reported on physical, mechanical, and thermal properties of PALF reinforced polymer composites with its potential applications.…”
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Synergistic potential of α-Phellandrene combined with conventional antifungal agents and its mechanism against antibiotic resistant Candida albicans by Riya Bhattacharya, Prashant Sharma, Debajyoti Bose, Manish Singh

“…In the era of multidrug-resistant diseases antibiotic resistance can be curtailed in its tracks with the help of combination treatments that allow for lower drug doses.…”
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Survival and Its Predictors Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma in Ethiopia: A 6-Year Follow-Up Study by Abigia Ashenafi, Soliyana Demelash, Efrata Melaku, Haymanot Abe, Meron Yitna, Fisseha Tekle, Jiksa Dabessa, Biniam Araya, Yared Nigussie, Wondmagegn Demsiss, Ashenafi Zelalem, Song Jung Kim, Nebiyu Dereje

“…PURPOSETo analyze survival and its predictors among patients with hepatocellular carcinoma (HCC) receiving transarterial chemoembolization (TACE) in Ethiopia.MATERIALS AND METHODSWe conducted a retrospective cohort study among patients who received TACE for HCC at MCM Hospital from December 1, 2016, to December 31, 2022. …”
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