Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction by Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

“…Moreover, we identified GPX4 as a gene involved in resistance and showed synergy between BET inhibition and ferroptosis induction.The present study demonstrated that dual BET/EP300 inhibitors have a relevant antitumor activity in a subgroup of UPS characterized by expression of MYC-targets pathway and identified a potent combination therapeutic strategy that deserves further investigation in the clinical setting.…”
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Effects of Dietary Pectin and Lactobacillus salivarius ATCC 11741 on Growth Performance, Immunocompetence, Gut Microbiota, Antioxidant Capacity, and Disease Resistance in Narrow-Cl... by Samyah Darwish Saddig Jastaniah, Hafsan Hafsan, Cheng-jui Tseng, Yasir Salam Karim, Mohammed Ubaid Hamza, Noora M. Hameed, Sura Hasan Al-Zubaidi, Saif Sabbar Kemil Almotlaq, Ghulam Yasin, A. Heri Iswanto, Mahnaz Dadras, Mohammad Mansouri Chorehi

“…The glutathione peroxidase (GPx) and superoxide dismutase (SOD) activity remarkably enhanced in LS1PE1 and LS2PE2, while malondialdehyde (MDA) content reduced in these two treatments. …”
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Effects of P1G10 against UVB-induced damage: Reduction of antioxidant stress, inflammation and cell proliferation by Kátia M. Freitas, Emerson S. Veloso, Ênio Ferreira, Marcelo V. Caliari, Carlos E. Salas, Miriam T.P. Lopes

“…Results: After repeated exposure to 240 mJ cm-2 UVB, P1G10 decreased by ∼50 % the detected ROS, enhanced glutathione peroxidase (GPx) and catalase activities, thereby protecting against oxidative stress. …”
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Dietary supplementation with 15% tomato pomace (Solanum lycopersicum L.) improves sperm production and antioxidant status in aged male broiler breeders by Amir Mosayyeb Zadeh, Seyyed Ali Mirghelenj, Mohsen Daneshyar, Mohsen Eslami, Mohammad Amir Karimi Torshizi, Mahdi Zhandi, Touba Nadri, John Patrick Kastelic, Peyman Hasanloo, Mehdi Nabiloo

“…The T-15 roosters had higher (P<0.05) serum testosterone concentration and testes glutathione peroxidase (GPx) activity. Superoxide dismutase (SOD) content was reduced (P<0.05) in L-10 roosters. …”
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Evaluation of longan (Dimocarpus longan) peel powder as fruit by-product additive in Nile tilapia (Oreochromis niloticus) feed: Effects on growth, immunity, and immune-antioxidant... by Supreya Wannavijit, Piyatida Outama, Chinh Le Xuan, Camilla Maria Fontana, Marina Paolucci, Md Afsar Ahmed Sumon, Ehab El-Haroun, Hien Van Doan

“…Similarly, analysis of mRNA transcripts of immune (IL-1, IL-8, and LBP) and antioxidant (GSTa, GPX, and GSR) gene expressions showed a significant upregulation (P < 0.05) in LP-fed diet groups compared to the control group. …”
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FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

“…It also reduced iron and MDA levels in lung tissue, increased GSH-Px activity, improved mitochondrial morphology, and enhanced the expression of GPX4 and SLC7A11, indicating its ferroptosis-inhibitory capacity. …”
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Dietary β-Mannanase Affects the Growth, Antioxidant, and Immunes Responses of African Catfish, Clarias gariepinus, and Its Challenge Against Aeromonas hydrophila Infection by Ibrahim Adeshina, Bilal Ahamad Paray, Eijaz Ahmed Bhat, Shahid Sherzada, Olaolu O. Fawole, Dalhatu J. Bawa, Thais Pereira da Cruz, Lateef O. Tiamiyu

“…In a dose-dependent order, including β-mannanase in the meals of African catfish raised the levels of glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD), glutathione-S-transferase (GST), and glutamate cysteine ligase (GCL) activities and decreased the malondialdehyde (MDA) values in African catfish (p <0.05). …”
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Effect of dietary supplementation of Lawsonia inermis and Acacia nilotica extract on growth performance, intestinal histopathology, and antioxidant status of broiler chickens chall... by Fares A. Eldeeb, Enas A. Noseer, Shimaa Abdelazeem, Esraa Ali, Asmaa W. Basher, M. A. A. Abdalla, Hytham H. Ibrahim

“…Challenged broilers had lower serum cholesterol, triglycerides, total protein, albumin, globulin, SOD, GPX & IL-10 levels compared to non-challenged broilers. …”
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Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

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Analysis of Nitrogen and Phosphorus Spatiotemporal Variations and Their Influencing Factors in Sansha Bay by CAO Nuotong, LI Qingsheng, JIANG Jinlong

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Razrada modela za utvrđivanje maksimalnog protoka vozila na putnoj mreži by Samir Šehović

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Izbor lokacija za smeštaj rezervi tehničkih materijalnih sredstava primjenom metoda operacionih istraživanja by Mladen Beović, Dušan Bobić, Salih Džafić

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A capacity coordination strategy for converters integrated with active damping functionality by ZHANG Kejia, DING Long, YANG Hu, YANG Jinming, CHEN Wang

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Comparative Study of Unsteady Flows in a Transonic Centrifugal Compressor with Vaneless and Vaned Diffusers by Cui Michael M.

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"Simulation and experiment of mixing performance of field synergy torsion screw" by "DAI Rui1, HUANG Shi-zheng1, PAN Wei1, ZHU Jia-wei1, ZENG Xian-kui1, YANG Wei-min2, JIAN Ran-ran1,3"

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"Molecular dynamics comparative study on properties of different fiber-reinforced nitrile rubbers" by SU Yu-hao1, LI Yun-long1, WANG Shi-jie1, NIE Rui2

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Research Progress and Governance Prospect of Marine Biodiversity Conservation Synergistic Response to Climate Change by LIN Ruijuan, JIANG Yuhuan, CHEN Fenggui, TAN Hongjian, ZHANG Jiwei

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Study on the Path of Cultivating and Enhancing National Maritime Awareness Under the Threshold of the Great Power Game by WANG Fuxin, GE Yuxuan

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Predictive Modeling in Higher Education: Determining Factors of Academic Performance by F. M. Gafarov, Ya. B. Rudneva, U. Yu. Sharifov

“…For this neural network model, the basic predictors that affect the accuracy of the forecast are the cumulative average level of achievement (CGPA) and the year of admission to the university.…”
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Spatiotemporal Pattern of Neuroinflammation After Impact-Acceleration Closed Head Injury in the Rat

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