SNX30 inhibits lung adenocarcinoma cell proliferation and induces cell ferroptosis through regulating SETDB1 by Xinjie Fan, Qichu Zhu, Chengzhuo Du, Jinlai Chen, Yingming Su

“…Cysteine (Cys), glutathione (GSH), and glutathione peroxidase 4 (GPX4) levels were measured using detection assay kits. …”
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Chorein deficiency promotes ferroptosis by Yoshiaki Nishizawa, Hitoshi Sakimoto, Omi Nagata, Natsuki Sasaki, Yuka Urata, Kaoru Arai, Hanae Hiwatashi, Izumi Yokoyama, Shosei Kishida, Akira Sano, Masayuki Nakamura

“…In the cytosolic fraction of VPS13A‐KD cells, the protein level of glutathione peroxidase 4 (GPX4) was significantly reduced, suggesting that dysfunction of chorein impairs GPX4 transport, thereby facilitating ferroptosis. …”
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Compressive Strength of Fly-Ash-Based Geopolymer Concrete by Gene Expression Programming and Random Forest by Mohsin Ali Khan, Shazim Ali Memon, Furqan Farooq, Muhammad Faisal Javed, Fahid Aslam, Rayed Alyousef

“…Fly ash (FA) is a residual from thermal industries that has been effectively utilized in the production of FA-based geopolymer concrete (FGPC). To avoid time-consuming and costly experimental procedures, soft computing techniques, namely, random forest regression (RFR) and gene expression programming (GEP), are used in this study to develop an empirical model for the prediction of compressive strength of FGPC. …”
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Eosinophilic granulomatosis with polyangiitis; a distinctive presentation with myocarditis and autoimmune haemolytic anaemia: case report by Doaa Abdulwahab Mohammed Ayish, Fatma Ayish, Asayel Khamjan, Amal. H. Mohamed, Nagla Abdalghani, Osama Albasheer

“…BackgroundEosinophilic granulomatosis with polyangiitis (EGPA) is an extremely rare type of vasculitis characterized by inflammation within small blood vessels or tissues that may cause damage to the lungs, heart, kidneys, and other organs. …”
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Ferroptosis Is a Potential Therapeutic Target for Pulmonary Infectious Diseases by Yurong Zhang, Dianlun Qian, Xiangfeng Bai, Shibo Sun

“…The dysregulation of iron metabolism, the accumulation of LPO, and the inactivation and consumption of glutathione peroxidase 4 (GPX4) are the crucial cause of ferroptosis. Pulmonary infectious diseases caused by Pseudomonas aeruginosa (PA), Mycobacterium tuberculosis (MTB), and severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) are associated with ferroptosis. …”
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THE NUMBER OF HOMOLOGS OF SOME ENZYMES IN THE TRYPTOPHAN BIOSYNTHESIS PATHWAY CORRELATES WITH THE PROPORTION OF PROTEINS ASSOCIATED WITH TRANSCRIPTION IN PLANTS by I. I. Turnaev, I. R. Akberdin, V. V. Suslov, D. A. Afonnikov

“…It is shown that organismal complexity significantly correlates with the total number of TBP paralogs and for some enzymes specifically (ASA/ASB, PAI, and IGPS). We suggest that such a relationship arises because both organismal complexity and the increasing number of paralogs may be important for the evolutionary adaptation of land plants to variable environmental conditions.…”
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Optimization of Black Garlic Protein Extraction Process and Exploration of Its Properties and Functions with Enzymatic Hydrolysis Products by Jian Liu, Yuanyuan Wang, Bo Wang, Wei Zhang, Xiaoyu Ren, Youchuang Zhang, Lijun Jiang, Chunming Dong, Guihong Zhao

“…In summary, the BGP extracted using the optimized process demonstrated good antioxidant and hypoglycemic activities, while its enzymatic hydrolysate BGPH-P exhibited excellent solubility, water-holding capacity, and emulsifying properties, providing valuable insights for the further development of black garlic protein and its hydrolysates.…”
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Superoxide dismutase promotes gastric tumorigenesis mediated by Helicobacter pylori and enhances resistance to 5-fluorouracil in gastric cancer by Hongbing Fu, Yu Zhang, Yantao Duan, Xin Zhang, Jun Yao, Dejun Yang, Ziran Wei, Zhenxin Zhu, Jiapeng Xu, Zunqi Hu, Qing You, Ronglin Yan, Weijun Wang

“…Our research demonstrates that SOD2 can serve as an inhibitor of ferroptosis by activating AKT, and stabilizing GPX4 protein, which subsequently induces 5-fluorouracil resistance. …”
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Effects of dietary bile acid on the growth performance, intestinal health, blood biochemistry, and antioxidative response of Nile tilapia (Oreochromus niloticus) fed high-fat diets by Mahmoud A.O. Dawood, Sameh El-Dahan, Samy Elsaadawy, Ahmed E. Noreldin, Hani Sewilam

“…On the other hand, fish-fed LF and HF/BA diets showed improved growth performance, lipase and amylase, GH, SOD, CAT, and GPx, and intestinal histo-morphology and reduced glucose, leptin, and MDA levels. …”
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Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k-AKT axis by Huizhen Xing, Xinwei Bai, Xiaoying Pei, Yuqi Zhang, Xueying Zhang, Shujun Chen, Dan Li, Bin Lv, Xiaoying Wang, Xiaoli Wu

“…They remarkably reduced ROS levels, and elevated the SOD and GPX enzyme activities in lung tissue to exert antioxidant effects. …”
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Dietary ferulic acid improves growth performance of broilers via enhanced intestinal antioxidant capacity and barrier function by Yaodong Hu, Shi Tang, Wei Zhao, Silu Wang, Caiyun Sun, Binlong Chen, Yuxing Zhu

“…On day 42, mRNA expression of GSS, NRF2, SOD1, and GPX1 in the jejunum and ileum as well as Claudin2 in the jejunum and Occludin in the ileum were increased in the FA200 group (p<0.05). …”
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Macrophage metabolic reprogramming ameliorates diabetes-induced microvascular dysfunction by Qiu-Yang Zhang, Hui-Ying Zhang, Si-Guo Feng, Mu-Di Yao, Jing-Juan Ding, Xiu-Miao Li, Rong Ye, Qing Liu, Jin Yao, Biao Yan

“…Mechanistically, cSPECC1 regulates GPX2 expression by recruiting eIF4A3, enhancing GPX2 mRNA stability and altering arachidonic acid metabolism. …”
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Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease by Zhihao Qi, Quan Li, Shuhua Yang, Chun Fu, Burong Hu

“…We found that DNA methylation of <i>Erbb2</i> and <i>Gpx1</i> significantly impacted their gene expression levels offering insights into the potential regulatory mechanisms of risk variants on IBD. …”
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برهمکنش آهن و سیلیسیم بر برخی از صفات بیوشیمیایی نخودفرنگی (Pisum sativum cv. Wando) در شرایط گلخانه‌ایی by ام لیلا عباسپور شاهمرس, فرزاد رسولی, فرهاد بهتاش, احمد آقایی

“…صفات بیوشیمیایی همچون کلروفیل کل، پروتئین محلول کل، میزان مالون‌دی‌آلدهید (MDA)، غلظت پراکسید‌هیدروژن و فعالیت ویژه آنزیم‌های کاتالاز (CAT)، گایاکول پراکسیداز (GPX) و آسکوربات پراکسیداز (APX) مورد ارزیابی قرار گرفتند. …”
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Pruebas de comportamiento caótico en índices bursátiles americanos by Franco Parisi, Christian Espinosa, Antonio Parisi

“…Este artículo valida el comportamiento caótico en las Bolsas de Valores de Argentina, Brasil, Canadá, Chile, Estados Unidos, Perú y México utilizando los índices accionarios Merval, Bovespa, S&P TSX Composite, IPSA, IGPA, S&P 500, Dow Jones Industrials, Nasdaq, IGBVL e IPC, respectivamente. …”
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Inclusiveness of economic growth in Indonesia: the poverty approach by Ahmad Soleh, Suwarni Suwarni

“…The inclusive growth coefficient (IGp) is smaller than the economic growth coefficient (Ĝg). …”
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Oxidative stress in critically ill neonatal foals by David Wong, Dipak Kumar Sahoo, Cosette Faivre, Jamie Kopper, Katie Dersh, Theresa Beachler, Melissa Esser

“…Significant lower CAT (healthy 0.4 ± 0.3 mU/mg protein, ill 0.02 ± 0.02 mU/mg protein, 95% CI), glutathione (healthy 238.5 ± 101.9 μg/mL, ill 110.7 ± 37.8 μg/mL, 95% CI; P < .0001), GR (healthy 1.6 ± 1.8 mU/mg protein, ill 0.4 ± 0.5 mU/mg protein, 95% CI), and GPx (healthy 0.01 ± 0.003 mU/mg protein, ill 0.007 ± 0.002 mU/mg protein, 95% CI) were also noted. …”
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Electroporation assisted delivery of Roussin salt porphyrin-based conjugated carbon nanoparticles for sono–X-ray–photodynamic prostate cancer in vitro and in vivo treatment by Samir Ali Abd El-Kaream, Abed Elrahman Ahmad Mohamad, Sohier Mahmoud El-Kholey, Samia Abd El-Moniem Ebied

“…Furthermore, EP@RRBP-CNP is a promising SXPS that, when used in conjunction with SXPDT, can be very effective in in vitro treating PCa-DU-145 (in a dose-dependent manner cell viability declined, an increase in the cells population during the G0/G1-phase indicates that the cell cycle was arrested, and an increase in cell population in the Pre-G, autophagic cell death, as well as necrosis and early and late apoptosis, indicate that cell death was induced) and MNU/testosterone-PCa-induced mice in vivo (induced antiproliferative genes, p53, Bax, TNFalpha, caspase 3,9, repressed antiangiogenic and antiapoptotic genes, VEGF and Bcl2, respectively), successfully slowing the growth of tumors and even killing cancer cells, as well as lowering oxidative stress (MDA), improving the functions of the kidneys (urea, creatinine), liver (ALT, AST), and antioxidants (GPx, GPx, GST, CAT, GSH, TAC). SXPDT, the X-ray photo- or sono-chemical RRBP activation mechanism, and the antioxidant capacity of non-activated RRBP can all be linked to this process. …”
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Impact of long-term cyanotoxin exposure on cattle: Biochemical, histological, and oxidative stress assessment by Mounira Bensalem, Amina Amrani, Hadjer Zaidi, Fateh Sedrati, Omar Laouar, Zhi Wang, Hichem Nasri

“…Antioxidant enzyme activities (GPx, CAT and SOD) were reduced, with notable depletion of GSH levels and increased lipid peroxidation. …”
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Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

“…Importantly, we found that PTGS2 knockdown could reduce the expression of MMP9 and MMP2 but increase GPX4 expression in macrophages. Conversely, while PTGS2 overexpression upregulated MMP9 and MMP2 expression but downregulated GPX4 expression, the regulatory effects of PTGS2 on these genes were largely blunted by ferroptosis inhibitors. …”
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