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circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4
Published 2025-01-01“…The circASAP1/HNRNPC/GPX4 axis provides novel directions and potential targets for RCC treatment.…”
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Source Impact Analysis Using Char-EC/Soot-EC Ratios in the Central Indo-Gangetic Plain (IGP) of India
Published 2021-06-01“…Our results demonstrate the advantages of utilizing the char-EC/soot-EC ratio rather than the OC/EC ratio as a tracer of these two sources in the IGP region.…”
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Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2
Published 2024-06-01Subjects: Get full text
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Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma
Published 2025-02-01Subjects: “…Ferroptosis;Cholangiocarcinoma;PDT;GPX4;AKT…”
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GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway
Published 2024-01-01“…Cultured STAD cells assessed the proliferation of STAD and upregulation of GPX3 expression by CCK8 and flow cytometry. Transwell and wound healing assays assessed the impact of GPX3 on invasion and migration of STAD cells. …”
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Associations of Vitamin D With GPX4 and Iron Parameters in Chronic Obstructive Pulmonary Disease Patients: A Case–Control Study
Published 2024-01-01“…Conclusions: Vitamin D deficiency is positively associated with GPX4 reduction and iron parameters elevation in COPD patients. …”
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Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway
Published 2025-01-01“…SESN2 silencing reduced the expression of System Xc− and GPX4, whereas overexpression of SESN2 promoted the expression of System Xc− and GPX4.DiscussionThese results suggest that SESN2 is a negative regulator of ferroptosis. …”
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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway.
Published 2025-01-01“…Dapagliflozin also decreased cardiac iron ion levels and increased Nrf2, HO-1 and GPX4 protein expression.<h4>Conclusion</h4>Dapagliflozin can improve heart failure by inhibiting oxidative stress and ferroptosis, and its mechanism may be related to the regulation of Nrf2/HO-1/GPX4 signaling pathway.…”
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THE CONCEPT OF ‘ALA BỤ ALA’: A SIGNAL FOR IGBO EXTINCTION
Published 2023-12-01Subjects: “…Igbo People…”
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IGAF: Incremental Guided Attention Fusion for Depth Super-Resolution
Published 2024-12-01“…Using IGAF, we build a robust super-resolution model and evaluate it on multiple benchmark datasets. …”
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New IGIP Curriculum for Advanced Training of Engineering University Teachers
Published 2021-01-01Subjects: Get full text
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Debating Igbo conversion to Christianity: a critical indigenous view
Published 2006-12-01Get full text
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An Evaluation of the Webpage of IGEME (Export Promotion Center of Turkey) Library
Published 2013-11-01Subjects: “…İGEME…”
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An Online Monitoring Method for Bond Wire Fatigue in IGBT Module
Published 2024-01-01Subjects: “…IGBT module…”
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IGJR 2/2019: Open topic issue on intergenerational justice
Published 2018-12-01“…The IGJR publishes articles from humanities, social sciences, and international law. …”
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The Application of Approximate Entropy Theory in Defects Detecting of IGBT Module
Published 2012-01-01“…Defect is one of the key factors in reducing the reliability of the insulated gate bipolar transistor (IGBT) module, so developing the diagnostic method for defects inside the IGBT module is an important measure to avoid catastrophic failure and improves the reliability of power electronic converters. …”
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Corrigendum to “Research on the Impact of Marine Environment on ICPT Transmission Efficiency”
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