Identification of Potential lncRNAs and miRNAs as Diagnostic Biomarkers for Papillary Thyroid Carcinoma Based on Machine Learning by Fei Yang, Jie Zhang, Baokun Li, Zhijun Zhao, Yan Liu, Zhen Zhao, Shanghua Jing, Guiying Wang

“…Overexpression of ADD3-AS1 inhibited cell growth and invasion in PTC cell lines. Conclusion. …”
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Statistical optimization of pectinases from thermophilic Aspergillus fumigatus BT-4 employing response surface methodology through submerged fermentation using agricultural wastes by Imran Ali, Roheena Abdullah, Sana Saqib, Kinza Nisar, Afshan Kaleem, Mehwish Iqtedar, Irfana Iqbal, Xiaoming Chen

“…Shake flask kinetics demonstrated the highest values of specific rate constant (qp), specific growth rate (µ), product yield coefficient (Yp/x), volumetric rate of product formation (Qp), and biomass formation (Qx) after 72 h of incubation. …”
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Analysis of the impact of climate change on the woody plants vegetation in the Botanical Garden of the Ukrainian National Forestry University by Nelia Lukianchuk, Levko Bliusyuk, Nadia Bliusyuk, Nataliіa Kendzora, Liliіa Koliada

“…Climatic changes have a significant impact on the growth and development of ornamental plants in the urban environment, the climatic conditions of the territory have a great impact on the ecological state of plants and determine their ability to adapt and develop in a certain region. …”
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Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis by Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z

“…The modified expression and functionality of CD36 may contribute to inflammation and oxidative stress in maternal tissues, interfere with insulin signaling, and subsequently influence maternal insulin sensitivity and fetal growth, increasing the risk for GDM. This review provides an overview of the current knowledge regarding the expression and function of CD36 in various tissues throughout pregnancy and explores how CD36 dysregulation can activate inflammatory pathways, worsen insulin resistance, and disrupt lipid metabolism, thereby complicating the necessary metabolic adjustments during pregnancy. …”
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CREB3L1 facilitates pancreatic tumor progression and reprograms intratumoral tumor-associated macrophages to shape an immunotherapy-resistance microenvironment by Yu Wang, Haiyan Xu, Li Cai, Yang Sun, Liwei Wang, Ming Yue, Xiaofei Zhang, Yanling Wang, Shumin Li, Shengbai Xue, Jingyu Ma, Tiebo Mao, Weiyu Ge, Daiyuan Shentu, Wenxin Lu, Yongchao Wang, Jiong Hu, Jiujie Cui

“…Functionally, we confirmed CREB3L1 contributing to PDAC malignant progression including growth and metastasis by multiple in in vitro and in vivo models. …”
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Evaluation of integrated sludge worm and catfish farming with biofloc system by Dedi Pardiansyah, Eddy Supriyono, Daniel Djokosetianto

“…The results showed that the highest production was obtained by treatment B at biomass growth of 0.97 kg/m2 and sludge worm density of 388.000 individu/m2.   …”
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Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…YXRJP can prolong the TWL, increase the MNCV of the sciatic nerve, alleviate the injury of the sciatic nerve, reduce the levels of triglyceride (TG), improve the expression of Insulin-like growth factor 1 (IGF-1) protein in the sciatic nerve, and reduce the expression of protein kinase B (AKT) protein. …”
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<i>Pleurotus ostreatus</i>: Nutritional Enhancement and Antioxidant Activity Improvement Through Cultivation on Spent Mushroom Substrate and Roots of Leafy Vegetables by Eirini-Maria Melanouri, Ilias Diamantis, Marianna Dedousi, Eleni Dalaka, Paraskevi Antonopoulou, Seraphim Papanikolaou, Ioannis Politis, Georgios Theodorou, Panagiota Diamantopoulou

“…The impact of SMS and RLV was first evaluated by the mycelial growth rate (Kr, mm/day). Afterwards, mushroom cultivation was conducted in bags, where production characteristics like earliness (the time from substrate inoculation to first harvest) and biological efficiency (BE %, the ratio of fresh mushroom weight to dry substrate weight × 100) were examined. …”
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Framework for smartphone-based grape detection and vineyard management using UAV-trained AI by Sergio Vélez, Mar Ariza-Sentís, Mario Triviño, Antonio Carlos Cob-Parro, Miquel Mila, João Valente

“…In addition, the AI-detected grape bunches were compared with the actual ground truth, achieving an R2 value as high as 0.84, showing the robustness of the system. …”
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MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

“…The study examines biomass as a resource with significant potential to meet local energy needs, create additional jobs and stimulate economic growth in rural areas. The paper discusses key aspects of the use of renewable energy sources, particularly biomass, in agriculture as an effective tool for local economic development, reducing dependence on traditional energy resources and increasing the country's energy security. …”
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Specificity of psychological readiness for changes and personality’s maturity of the employees of the state criminal and executive service by O. V. Mitroshkina

“…It was proved that the groups of the employees of the Criminal and Executive Service with different levels of psychological readiness for changes show differences in the structure of interrelationships between the components of psychological readiness for changes and the components of personal maturity. In both groups, the growth of personality maturity is accompanied by a facilitation of psychological readiness for changes. …”
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不同剂量苯那普利对自发性高血压大鼠肾小球硬化的影响

“…【目的】 观察超大剂量血管紧张素转化酶抑制剂干预能否进一步抑制肾小球硬化65377;【方法】 30只8周龄雄性自发性高血压大鼠随机分为模型对照组(M组),大剂量(10 mg·kg-1·d-1)苯那普利治疗组(LT组),超大剂量(50 mg·kg-1·d-1)苯那普利治疗组(HT组),以10只Wistar-Kyoto大鼠(Wistar-Kyoto rats,WKY)为正常对照组(N组)65377;检测各组大鼠的血压65380;血清肌酐及24 h尿蛋白;RT-PCR和免疫组织化学方法分别检测肾组织转化生长因子-β1(transforming growth factor,TGF-β1)和纤溶酶原激活物抑制因子(Plasminogen Activator Inhibitor,PAI-1)的mRNA和蛋白表达;肾组织石蜡切片评估肾小球胶原沉积程度,采用MASSON染色65377; 【结果】 1)TGF-β1和PAI-1的mRNA和蛋白表达:LT组和HT组的TGF-β1和PAI-1 的mRNA和蛋白表达被抑制(P < 0.01);两治疗组间无统计学差异(P > 0.05)65377;2)肾小球胶原沉积:LT组和HT组的胶原面积/肾小球面积比值均明显减低(0.17 ± 0.15, 0.18 ± 0.11 vs 0.30 ± 0.28; P = 0.001);两治疗组间无统计学差异(0.17 ± 0.15 vs 0.18 ± 0.11; P=0.404)65377;【结论】 大剂量与超大剂量血管紧张素转化酶抑制剂均能降低血压,减少蛋白尿,抑制肾组织TGF-β1和PAI-1的mRNA和蛋白表达,延缓肾小球硬化;但超大剂量血管紧张素转化酶抑制剂不能进一步的抑制肾小球硬化65377;…”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…Cell proliferation ability in vitro and the ability of growth and metastasis in mouse tumor models were compared between KO/OE and wild-type tumor cells. …”
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Effects of MyBFF@school, a multifaceted obesity intervention program, on anthropometry and body composition of overweight and obese primary schoolchildren by Ruziana Mona Wan Mohd Zin, Abdul Halim Mokhtar, Abqariyah Yahya, Fuziah Md. Zain, Rusidah Selamat, Zahari Ishak, Muhammad Yazid Jalaludin

“…A total of 1,397 primary-school students aged 9–11 with a body mass index (BMI) $$z$$ z -score (corrected for age) greater than + 1 standard deviation based on the World Health Organization 2007 Growth Reference were assigned to intervention ( $$n=647$$ n = 647 ) and control ( $$n=750$$ n = 750 ) groups. …”
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DESENVOLVIMENTO DE PRODUTOS DE FORMA EFICIENTE NAS ORGANIZAÇÕES ATUAIS by Marlons Lino da Cruz, Antonio Marcos de Oliveira Siqueira, Israel Iasbik, José Damato Neto

“… A B S T R A C T Due to market and technological competition, today's organizations they need tools that yield sufficient benefits for their growth. The objective of this research is to present the importance of product development efficient in today's organizations. …”
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Soil moisture partitioning strategies in blowouts in the Hulunbeier grassland and response to rainfall by Zhixin Bao, Limin Yuan, Limin Yuan, Limin Yuan, Zhongju Meng, Ezhen Zhang, Lei Zhu, Jinwang Liu

“…IntroductionSoil moisture and soil water retention capacity are key influencing factors for the normal growth and development of vegetation. Understanding the dynamic change characteristics of soil moisture in blowouts and soil water retention capacity is of great significance for the management of blowouts.MethodsThis study employs drying and in situ monitoring methods to select typical blowouts in different regions (sand pits, fringe zones, sand accumulation zones, and sand-grass transition zones) on the Hulunbuir Grassland. …”
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Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“…Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. …”
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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

“…Conclusions AGD1 mediates the stemness and apoptosis of PCSCs and promotes docetaxel treatment resistance by enhancing tumor growth and metastasis through USP10/METTL13-mediated CD44 mRNA decay in CRPC.…”
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MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

“…Additionally, we discovered that MAZ was significantly expressed in C3 PCLAF+ tumor cells subtype, and in vitro experiments confirmed that MAZ knockdown inhibited tumor growth, accentuating its underlying ability as a therapeutic target. …”
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The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

“…**Conclusions:** Patients with nAMD continue to experience more vision impairment and worse functional status compared with a similar population of Medicare beneficiaries despite availability of therapies like antivascular endothelial growth factor to treat retinal disease.…”
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