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28081
RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Sna...
Published 2014-11-01“…In vitro, a well-established experimental EMT model involving transforming growth factor β1 (TGF-β1) was applied. Viability, invasion and migration, protein and mRNA expression of tumor cells were analyzed by MTT assay, transwell assay, western blot and real-time PCR, respectively. …”
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28082
Vertical and horizontal bone loss following alveolar socket preservation using bone grafts and autologous platelet concentrates vs bone grafts alone: a systematic review and meta-a...
Published 2025-02-01“…Abstract Background Socket preservation is a proactive approach that limits bone loss after tooth extraction to maintain adequate bone volume, height and width. …”
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28083
Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway
Published 2024-08-01“…Network pharmacology analysis and molecular docking identify epidermal growth factor receptor (EGFR) as a potential target for VAC. …”
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28084
Insights into the effects of biomass feedstock and pyrolysis conditions on the energy storage capacity and durability of standard biochar-based phase-change composites
Published 2025-01-01“…The crystalline temperature increased slightly from 10.7 °C in RH550/HXD to 10.9 °C in RH700/HXD, suggesting improved molecular motion and crystal growth of HXD. Wheat straw biomass pyrolyzed at a low temperature (550 °C), displaying a reduced surface area at 700 °C (7.35 m2 g−1) and exhibiting the lowest energy storage density. …”
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28085
Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans.
Published 2025-01-01“…About one-third of the score of mutants that enhance RNAi are in synMuv B genes, identified 30 years ago in unrelated screens for increased growth factor signaling. Many synMuv B genes encode dREAM complex chromatin-regulatory proteins found in nearly all animals and plants. …”
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28086
Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
Published 2025-02-01“…Consistent with the role of these proteins in BMC assembly and metabolism, deletion of eutN, eutL/eutM1/eutM2, or eutL/eutM1/eutM2/eutN not only affected BMC formation but also ethanolamine utilization, causing cell growth defects with ethanolamine as a nutrient. BMCs are also assembled in fusobacteria cultured with placental cells or the culture media, a process that is dependent on the BMC shell proteins. …”
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28087
Exploring Glypican-3 targeted CAR-NK treatment and potential therapy resistance in hepatocellular carcinoma.
Published 2025-01-01“…We found that NK92MI/HN3 cells, rather than NK92MI/HS20 cells, exhibited a significant cytotoxicity effect against GPC3+ HepG2 cells in vitro and efficiently suppressed tumor growth in a xenograft model using NSG mice. In addition, irradiated NK92MI/HN3 cells displayed similar anti-tumor efficacy to unirradiated NK92MI/HN3 cells. …”
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28088
CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors
Published 2025-02-01“…We characterized CAR and endogenous tumor-specific memory T cell precursors, establishment of circulating (TCIRC) and resident (TRM) memory T cell subsets, and ability to protect against secondary tumors.Results TRP1-specific or NKG2D CAR T cells had no effect on primary tumor growth in immunocompetent mice unless they were combined with S233 armoring or CD4 depletion. …”
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28089
E-business tools adoption and export performance: Empirical evidence from Croatian companies
Published 2019-01-01“…ICT empowers the company’s potential to contribute significantly to economic growth, as it plays a vital role in simplifying business processes and contributes to the improvement of the competitive market presence of a company. …”
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28090
Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens
Published 2025-02-01“…Furthermore, nucleotide/nucleoside reverse transcriptase inhibitors (NRTIs) completely prevent tissue damage and subsequent bacterial growth within necrotic lesions. Since liver necrosis is linked to heightened systemic inflammatory responses, we hypothesized that NRTIs diminish inflammation caused by E. coli infection and may also have broad impacts on the systemic immune response to bacterial pathogens. …”
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28091
New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach
Published 2025-02-01“…Recent research indicates that gut microbiota might be pivotal in RA development through the “gut-joint axis,” presenting novel therapeutic possibilities.PurposeThis study seeks to explore the therapeutic potential of the traditional Chinese medicine (TCM) compound new bitongling (NBTL) for RA, with an emphasis on its capacity to regulate gut microbiota and suppress angiogenesis via the vascular endothelial growth factor (VEGF) signaling pathway.MethodsWe utilized a collagen-induced arthritis (CIA) rat model to assess the impact of NBTL. …”
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28092
Effects of PBAT on Soil Water and Salt in Maize Root Zone and Maize Yield in Saline-alkali Land
Published 2024-12-01“…The degradability of degradable film and its effect on soil water and salt transport and maize growth were studied. [Results] The water content in the 0-20 cm soil layer under black and white fully biodegradable mulch film was 18.87% and 18.34% higher than that under ordinary PE film, respectively, and 1.16% and 0.72% higher than that without mulching, respectively, and the soil salt content under black and white PBAT fully biodegradable film mulching and ordinary PE film mulching was reduced by 15.01%~23.10% compared with that without mulching (p<0.05). …”
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28093
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
Published 2025-01-01“…In vivo experimental results showed that RosA could inhibit the growth of transplanted tumors in nude mice bearing tumors of lung cancer cells, reduce the positive expression of Ki67 in lung tumor tissue, and hinder the proliferation of lung tumor cells. …”
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28094
Reproductive performance of female largemouth bass (Micropterus salmoides) broodstock was enhanced by dietary small peptides
Published 2025-03-01“…The mRNA expression levels of vgr (1.90 ± 0.29), insulin-like growth factor-1 (1.53 ± 0.67), steroidogenic acute regulatory protein (2.59 ± 0.78), fshr (1.97 ± 0.35) and cyp17a (2.78 ± 1.32) in gonad were up-regulated in the HS group (P < 0.05). …”
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28095
Morfometric evaluation of young buffalo males in two Argentinean herds
Published 2023-11-01“…A significant correlation between LW and TP and LW with AH, SH, and SC was observed in both herds. There were significant values of Pearson’s equation in the correlation between BS and SC in the animals from the Empedrado locality and when considering the animals from both locations, but not in those from the Itatí establishment. …”
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28096
Multispectral, Thermal, and Hyperspectral Sensing Data Depict Stomatal Conductance in Grapevine
Published 2025-01-01“…Data were collected at the following growth stages: 80 and 44 days before harvest (DBH) in 2016; and 64, 44, and 8 DBH in 2017. …”
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28097
Bank Credit and Loan Repayment During Covid-19 In Kabale District: A Case of Lyamujungu SACCO.
Published 2023“…Results for the first study objective revealed that the outbreak of Covid-19 led to a drop in labour productivity growth (4.73, SD =.523), a major issue that affected borrowers’ character in loan repayment. …”
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28098
The Relationship Between Mindset and Poverty Levels in Kisinga Sub-County Kasese District
Published 2024“…Investments in infrastructure and education reduce rural poverty mainly by spurring nonfarm employment and growth in agricultural productivity. Uganda should continue its investments in health care, but future investments should be geared toward improving the efficiency of existing public health-care systems. …”
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28099
Impact of Tourism on Social Economic Development of Kabale Municipality Kabale District.
Published 2024“…These included senior staff, Head Guide, Manager, Tourists, Community members Local government officials. Both simple random and purposive sampling techniques in identifying the study sample population. …”
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28100
Assessing the Impact of Social Media Usage and Performance of the Selected Small and Medium Businesses in Ntungamo District.
Published 2024“…The study was guided by the following objectives; to evaluate whether small business‟ owner-managers” in the Ntungamo district find any importance of social media in their businesses, to determine the performance of small businesses in the Ntungamo district after adaptation of social media compared to the one without social media and to find the challenges encountered when small business owner-managers in Ntungamo district use social media in their business in Ntungamo district The study adopted a descriptive research design comprising of both qualitative and quantitative approaches. The study included different retail shop owners such as; clothing, cosmetics, electronic accessories, make-up services, home appliances, and food stuffs. …”
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Thesis