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27721
The optimal treatment of invasive ductal and lobular carcinoma occurring at the same time needs to be established
Published 2025-01-01“…IDC, the most common breast cancer subtype, is known for its aggressive behaviour, nodal involvement and metastatic potential, while ILC, representing a smaller percentage of breast cancers, often exhibits an indolent course with diffuse growth patterns. Both tumours in this patient were hormone receptor-positive (ER/PR-positive) and HER2-negative, warranting targeted endocrine therapies. …”
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27722
The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathw...
Published 2025-01-01“…The expression levels of interleukin-1β (IL-1β), IL-6, IL-8, interferon alpha 2 (IFNA2), IFNB1, intercellular adhesion molecule 1 (ICAM-1), chemokine (C-C motif) ligand 4 (CCL-4), collagen I, collagen V, lysyl oxidase (LOX), transforming growth factor β 1(TGF-β1) were measured using qPCR, ELISA, or western blot. …”
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27723
Rootstocks for Florida Stone Fruit
Published 2018-11-01“… Rootstocks have been used in many tree fruit systems to provide growth advantages and/or pest and disease resistance without affecting (or sometimes improving) productivity and fruit quality. …”
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27724
A Zinc Polyphenolic Compound Increases Maize Resistance Against Infection by <i>Bipolaris maydis</i>
Published 2024-12-01“…Plants were sprayed with water (control) or Semia<sup>®</sup> (referred to as induced resistance (IR) stimulus hereafter) and not inoculated or inoculated with <i>B. maydis</i>. The mycelial growth and conidium germination were significantly reduced by the IR stimulus in vitro. …”
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27725
Bacteriological quality and predictors of raw meat collected from municipal slaughterhouse and butcher shops in northeast, Ethiopia
Published 2025-01-01“…It is the most perishable food item since it has enough nutrients to enable microbial growth. In underdeveloped nations, animals are routinely slaughtered and sold in unsanitary conditions, compromising the bacteriological quality and safety of the meat received from the animals. …”
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27726
Pan-Cancer Analysis of the Prognostic and Immunotherapeutic Value of PDGFB
Published 2025-01-01“…Identifying novel cancer targets is crucial to developing more effective cancer treatments. Platelet-derived growth factor-B (PDGFB) plays a critical role in various tumor processes, including angiogenesis and lymphatic metastasis. …”
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27727
The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection
Published 2024-12-01“…Diagnostics of infectious complications in joint replacement surgery remains a significant challenge, particularly when microbiological analysis of biological material fails to reveal pathogen growth. The aim of the study was to determine threshold values for C-reactive protein, interleukin-6, and presepsin levels, and to assess their diagnostic value in detecting periprosthetic joint infection. …”
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27728
A combined model of shoot phosphorus uptake based on sparse data and active learning algorithm
Published 2025-01-01“…Shoot P uptake (SPU) is an important parameter for monitoring crop growth and health and for improving field nutrition management and fertilization strategies. …”
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27729
Radiolabeled Anti-Adenosine Triphosphate Synthase Monoclonal Antibody as a Theragnostic Agent Targeting Angiogenesis
Published 2017-12-01“…For radioimmunotherapy, 18.5 MBq 131 I-ATPS mAb (n = 7), isotype immunoglobulin G (IgG) (n = 6), and vehicle (n = 6) were injected into MKN-45 tumor-bearing mice for 4 weeks, and tumor volume and percentage of tumor growth inhibition (TGI) were compared each week. Results: MKN-45 cells showed the highest in vitro cellular binding after 4 hours (0.00324 ± 0.00013%/μg), which was significantly inhibited by unlabeled ATPS mAb at concentrations of greater than 0.4 μM. …”
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27730
Yoga Practice as a Potential Sarcopenia Prevention Strategy in Indonesian Older Adults: A Cross-Sectional Study
Published 2025-01-01“…The research focused on key biomarkers and functional assessments, including serum insulin-like growth factor 1 (IGF-1) levels, telomere length, gait speed, hand grip strength, and SARC-F questionnaire scores.Results: The results showed that participants aged 71– 80 years who practiced yoga for more than a year had significantly higher IGF-1 levels (p=0.04). …”
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27731
Appropriate Timing of Gestational Diabetes Mellitus Diagnosis in Medium- and Low-Risk Women: Effectiveness of the Italian NHS Recommendations in Preventing Fetal Macrosomia
Published 2020-01-01“…In MR and LR women with GDM, a mild acceleration of fetal growth can be detected at the time of anomaly scan. …”
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27732
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner
Published 2025-02-01“…In vivo experiments further indicated targeting NCAPD3 suppressed tumor growth. Noteworthily, NCAPD3 deficiency disturbed the mitosis, triggering the formation of aneuploids. …”
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27733
Retrospective Analysis Comparing Lung-RADS v2022 and British Thoracic Society Guidelines for Differentiating Lung Metastases from Primary Lung Cancer
Published 2025-01-01“…CT images characterized nodules based on size, number, location, margins, attenuation, and growth patterns. Nodules were classified according to Lung-RADS Version 2022 and BTS guidelines. …”
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27734
A data-driven machine learning algorithm to predict the effectiveness of inulin intervention against type II diabetes
Published 2025-01-01“…Inulin, a fructan-type soluble fiber that promotes the growth of probiotic species like Bifidobacterium and Lactobacillus, is commonly used in nutritional interventions for T2DM. …”
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27735
Emotional Intervention and Education System Construction for Rural Children Based on Semantic Analysis
Published 2022-01-01“…Under the background of the policy of caring for the healthy growth of left-behind children, the purpose of selecting the topic is to study some common negative emotional problems of left-behind children in rural areas, focusing on the guidance of negative emotions of left-behind children in rural areas. …”
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27736
Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley
Published 2025-01-01“…Using RNA-seq, small RNA sequencing (miRNA-seq) combined with degradome sequencing (degradome-seq), four pairs associated with leaf-stripe miRNAs and target genes were obtained, namely Hvu-miR168-5p and Argonaute1 (HvAGO1), Hvu-novel-52 and growth-regulating factor 6 (HvGRF6), Hvu-miR6195 and chemocyanin-like protein (CLP), and Hvu-miR159b and gibberellin-dependent MYB (GAMYB). …”
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27737
The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer
Published 2025-01-01“…The aim of this study was to investigate whether soluble programmed cell death-ligand 1 (sPD-L1) could be a predictive biomarker in patients with epidermal growth factor receptor (EGFR)-positive NSCLC. Materials and Methods: Blood samples from 35 patients with EGFR-mutated (EGFRmut) adenocarcinoma who achieved disease control with EGFR tyrosine kinase inhibitor (EGFR TKI) therapy were collected for sPD-L1 analysis. …”
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27738
The mechanism of tea tree oil regulating the damage of hydrogen sulfide to spleen and intestine of chicken
Published 2025-01-01“…In conclusion, TTO can improve spleen and intestinal function and reduce the effects of H2S on growth performance and health of chickens.…”
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27739
Preliminary application of a cervical vertebra segmentation method based on Transformer and diffusion model for lateral cephalometric radiographs in orthodontic clinical practice
Published 2024-12-01“…Objective·To construct a cervical vertebra image segmentation model by using a diffusion model with the Transformer deep learning algorithm, and evaluate its segmentation performance, to address the clinical challenge of accurately assessing complex changes in skeletal morphology during the growth and developmental peaks of malocclusion.Methods·Accurate cervical vertebra segmentation was performed on cephalometric radiographs from 185 orthodontic patients (44 cases from the Stomatological Hospital of Chongqing Medical University and 141 cases from the Stomatological Hospital of Xi'an Jiaotong University) by using a method combining Transformer and diffusion models. …”
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27740
Ellipsoid Zone Integrity and Visual Acuity Changes during Diabetic Macular Edema Therapy: A Longitudinal Study
Published 2021-01-01“…This study is aimed at describing the long-term VA and anatomical outcomes in spectral domain optical coherence tomography (OCT) (relative ellipsoid zone reflectivity ratio, central macular thickness, and volume) in patients with DME treated with antivascular endothelial growth factor (anti-VEGF) therapy. Furthermore, we studied the correlation between EZ integrity and changes in visual acuity. …”
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