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27221
The diagnostic accuracy of circulating free DNA for the detection of KRAS mutation status in colorectal cancer: A meta‐analysis
Published 2019-03-01“…Abstract KRAS mutations have been reported as a reliable biomarker for epidermal growth factor receptor (EGFR) targeted therapy and are also associated with poor prognosis in colorectal cancer (CRC) patients. …”
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27222
IGF2BP2 Regulates the Progression of Alzheimer's Disease Through m6A‐Mediated NLRP3 Inflammasome
Published 2025-01-01“…Aims The present study aimed to explore the effect of human insulin‐like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2), one of the m6A‐binding proteins on the progression of AD. …”
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27223
Distribution, Risk Assessment, and Quantitative Source Analysis of Soil Heavy Metals in a Typical Agricultural City of East-Central China
Published 2025-01-01“…The land use in agricultural areas contributes to economic growth while concurrently accompanied by a series of environmental pollution issues. …”
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27224
The Effectiveness of Varying Combination Ratios of A. cordifolia and M. indica against Field and Laboratory Strains of P. falciparum In Vitro
Published 2020-01-01“…This present study explored the effectiveness of combinations of aqueous extracts of Alchornea cordifolia (A. cordifolia) and Mangifera indica (M. indica) at clearing both laboratory and field isolates of P. falciparum. …”
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27225
Revisiting teacher educators' training in Ethiopia: Implications for a new approach to curriculum development
Published 2023-06-01“…Furthermore, secondary data sources such as the National Learning Assessment results (MoE, 2000–2016), Education Sector Development Program documents (2010–2015), Growth and Transformation Plan I (GTP I) (MoFED, 2010) and GTP II (National Plan Commission, 2016), previous MEd curricular documents in science and mathematics education, as well as existing research outputs were examined. …”
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27226
Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040
Published 2025-01-01“…Decomposition analysis revealed that population growth and aging were the primary drivers of the increased disease burden. …”
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27227
Enhancing precision in cancer treatment: the role of gene therapy and immune modulation in oncology
Published 2025-01-01“…This review highlights innovative therapeutic strategies, including gene replacement, gene silencing, oncolytic virotherapy, CAR-T cell therapy, and CRISPR-Cas9 gene editing, with a focus on their application in both hematologic malignancies and solid tumors. CRISPR-Cas9, a revolutionary tool in precision medicine, enables precise editing of cancer-driving mutations, enhancing immune responses and disrupting tumor growth mechanisms. …”
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27228
Seed regeneration of green ash (Fraxinus pennsylvanica Marshall) in green spaces of Petrozavodsk city
Published 2024-12-01“…In the northern region there are not many beautiful broad-leaved woody species that demonstrate successful growth in urban environments. Green ash should not be excluded from the list of species used in landscaping in Petrozavodsk in present climate conditions. …”
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27229
Mid-Epidemic Forecasts of COVID-19 Cases and Deaths: A Bivariate Model Applied to the UK
Published 2021-01-01“…Commonly applied methods to analyse epidemic trajectories or make forecasts include phenomenological growth models (e.g., the Richards family of densities) and variants of the susceptible-infected-recovered (SIR) compartment model. …”
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27230
Solid Indeterminate Pulmonary Nodules Less Than or Equal to 250 mm3: Application of the Updated Fleischner Society Guidelines in Clinical Practice
Published 2019-01-01“…None of the SIPNs < 100 mm3 in low-risk patients showed significant growth during the follow-up period. The application of the new guidelines would have led to a significant reduction in follow-up CT examinations (Hodges-Lehmann median difference, -2 CT scans; p = 0.0001). …”
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27231
Combined Catheter Ablation and Left Atrial Appendage Closure in Atrial Fibrillation Patients with and without Prior Stroke
Published 2021-01-01“…Combined atrial fibrillation (AF) ablation and left atrial appendage closure (LAAC) has been practiced for management of both the symptoms and the high stroke risk of AF. …”
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27232
Long non-coding RNA OSTM1-AS1 promotes renal cell carcinoma progression by sponging miR-491-5p and upregulating MMP-9
Published 2025-01-01“…The in vivo trial demonstrated that OSTM1-AS1 suppression resulted in tumor growth inhibition among nude mice. In summary, our findings indicate, for the first time, at least to the best of our knowledge, that OSTM1-AS1 serves as an oncogene among RCC by promoting proliferation, invasion, and metastasis through its targeting of the miR-491-5p/MMP9 axis. …”
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27233
Natural Concurrent Infections with Black Spot Disease and Multiple Bacteriosis in Farmed Nile Tilapia in Central Kenya
Published 2020-01-01“…In conclusion, these findings suggest that coinfections by these organisms coupled by water quality-related stress can be associated with low-grade mortality observed in postfingerling tilapia as well as reduced growth. The authors recommended immediate destocking, thorough disinfection, and control of piscivorous birds. …”
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27234
Meta-QTL analysis reveals the important genomics regions for biotic stresses, nutritional quality and yield related traits in pearl millet
Published 2024-04-01“…Among 34 Meta-QTL regions, Meta-QTL1.1 is found to be region of significant importance as it harbours genes for enhanced biotic stress tolerance, plant growth and development as well as genes related with enhanced seed development. …”
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27235
Biofilm as a supracellular organization of pathogenic bacteria
Published 2024-12-01“…The processed literature describes a number of hypotheses regarding the participation of "toxin-antitoxin" systems that control the growth and metabolism of bacteria in the stimulation of the formation of persister cells. …”
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27236
Prevalence and Intensity of Intestinal Helminth Infections in Preschool Pupils in Lugari Subcounty, Kakamega County, Kenya
Published 2020-01-01“…Intestinal helminths cause anaemia, malnutrition, indigestion disorders, retarded growth, and low mental abilities in pupils. About 1.5 billion are infected globally. …”
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27237
Phytochemical and Antimicrobial Study for Phoenix dactylifera L. (Ajwa Date) Seeds Extract
Published 2024-12-01“…The seed extract suppresses the growth of some bacterial types under study, especially the Gram-negative ones. …”
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27238
Analysis of the Impact of Fault Mechanism Radiation Patterns on Macroseismic Fields in the Epicentral Area of 1998 and 2004 Krn Mountains Earthquakes (NW Slovenia)
Published 2014-01-01“…Seismotectonically the difference is explained as an active growth of the Ravne fault at its NW end. The radiation patterns of both events were studied to explain their possible impact on the observed variations in macroseismic fields and damage distribution. …”
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27239
Genome-wide identification of oat TCP gene family and expression patterns under abiotic stress
Published 2025-02-01“…Additionally, various cis-acting elements related to hormone response, abiotic stress, light response, and growth and development were found in the promoters of AsTCP genes. …”
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27240
Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway
Published 2025-02-01“…Western blot and immunofluorescence staining were used to detect the expression levels of key proteins and their phosphorylated forms, such as transforming growth factor beta-activated kinase 1 (TAK1), P38 mitogen-activated protein kinase (P38 MAPK), and eukaryotic initiation factor 4E (eIF-4E). …”
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