Optogenetic control of horizontally acquired genes prevent stuck fermentations in yeast by David Figueroa, Diego Ruiz, Nicolò Tellini, Matteo De Chiara, Eduardo I. Kessi-Pérez, Claudio Martínez, Gianni Liti, Amparo Querol, José M. Guillamón, Francisco Salinas

“…Our results show that changes in gene expression for genes within this region can impact growth parameters and fermentation rate. We additionally found that the expression of various genes in region A is necessary to complete the fermentation process and prevent stuck fermentations under low nitrogen conditions. …”
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Spatiotemporal Variation and Driving Factors of Carbon Sequestration Rate in Terrestrial Ecosystems of Ningxia, China by Yi Zhang, Chunxiao Cheng, Zhihui Wang, Hongxin Hai, Lulu Miao

“…The results show that from 2001 to 2023, the CSR of the Ningxia ecosystem exhibits a spatial distribution pattern characterized by higher values in the south and lower values in the north, with a mean value of 21.95 gC·m⁻², and an overall fluctuating increasing trend, with an annual growth rate of 0.53 gC·m⁻² a⁻¹. …”
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Prevention of mother-to-child transmission of hepatitis B virus: protocol for a one-arm, open-label intervention study to estimate the optimal timing of tenofovir in pregnancy by François Nosten, Rose McGready, Verena Carrara, Stephan Ehrhardt, Chaisiri Angkurawaranon, Nan Guo, Yuanxi Jia, Marieke Bierhoff, Kenrad E Nelson, Podjanee Jittamala, Wanitda Watthanaworawit, Clare Ling, Fuanglada Tongprasert, Michele van Vugt, Marcus Rijken, Chloe Lynne Thio

“…Infants will receive HBV vaccinations at birth, 2, 4 and 6 months and hepatitis B immunoglobulin at birth if the mother is hepatitis B e antigen positive. Infant growth and neurodevelopment at 6 months will be compared with established local norms.Ethics and dissemination This study has ethical approval by the Ethics Committee of the Faculty of Tropical Medicine, Mahidol University (FTM ECF-019-06), Johns Hopkins University (IRB no: 00007432), Chiang Mai University (FAM-2559-04227), Oxford Tropical Research Ethics Committee (OxTREC Reference: 49-16) and by the local Tak Community Advisory Board (TCAB-02/REV/2016). …”
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Biotechnological methods as a tool for efficient sugar beet breeding by T. P. Zhuzhzhalova, E. O. Kolesnikova, E. N. Vasilchenko, N. N. Cherkasova

“…The influence of in vitro growth conditions on haploid cells of unfertilized sugar beet ovules in the course of obtaining doubled haploid lines with high degree of homozygosity and maintenance of valuable breeding properties is considered. …”
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A clean energy Korea by 2035: Transitioning to 80% carbon-free electricity generation by Won Young Park, Yong Hyun Song, Nikit Abhyankar, Hee Seung Moon, Umed Paliwal, Eunsung Kim, Nina Khanna, Sanghyun Hong, James Hyungkwan Kim, Kenji Shiraishi, Jiang Lin, Seung Wan Kim, Amol Phadke

“…We find that transitioning to 80% clean electricity—comprising 50% renewables and 30% nuclear—alongside investments in storage and transmission is both economically desirable and operationally feasible. …”
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The highly prolific phenotype of Lacaune sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary. by Laurence Drouilhet, Camille Mansanet, Julien Sarry, Kamila Tabet, Philippe Bardou, Florent Woloszyn, Jérome Lluch, Grégoire Harichaux, Catherine Viguié, Danielle Monniaux, Loys Bodin, Philippe Mulsant, Stéphane Fabre

“…The reduced FecL locus contained only two genes, insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) and beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4GALNT2), and we identified two SNP in complete linkage disequilibrium with FecL(L) . …”
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The Multifaceted Contributions of Community-Based Breeding Program of Bonga Sheep to Flock Dynamics, Animal Performance, and Socio-economic Benefits of Beneficiaries in Kafa Zone,... by Metsafe Mamiru, Aberra Melesse, Aynalem Haile, Tesfaye Getachew

“…Technical evaluation of the program reported outstanding outcomes in growth and reproductive traits of the animals. Further participatory evaluation allowing farmers to assess the relevance and impact of such programs has been suggested. …”
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The Contribution of Education, Health, and Unemployment on HDI in East Java, Indonesia by Amrun Rosyid, Elok Damayanti, Sarmilah Sarmilah, ST Rohani, Syalwa Shabila

“…The findings confirm that increasing education levels and improving healthcare access contribute positively to human development, whereas higher unemployment rates hinder HDI growth. The coefficient of determination (R²) suggests that these three factors collectively explain a substantial portion of HDI variation in East Java. …”
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Effect of melatonin on the contents of fatty acids and antioxidants of saffron by Mohammad Mehdi Samim, Ali Sorooshzadeh, Ali Mokhtassi-Bidgoli, Mohammad Sadegh Sabet

“…This study aimed to examine the changes in saffron leaf composition and evaluate the effects of melatonin foliar application during the late growth stage. The research was conducted over two consecutive cropping years (2020–2021 and 2021–2022). …”
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Predictive factors for axillary pathological complete response to neoadjuvant therapy in elderly breast cancer patients by Yuying Wang, Rui Wang, Di Lu, Yaling Zeng, Xihui Tu, Shiwei Liu, Purong Zhang

“…The univariate analysis results showed that the initial clinical lymph nodes negative(cN0) stage, Human Epidermal Growth Factor Receptor 2(HER2) positivity and breast pathological complete response(bpCR) were significantly correlated with high apCR rates(all P < 0.05). …”
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Application of trichloroisocyanuric acid in controlling kiwifruit bacterial canker disease demonstrates its promising potential as an eco-friendly bactericide by Jianyou Gao, Jiewei Li, Cuixia Liu, Hongjuan Gong, Beibei Qi, Rongxiang Zhu, Liming Xia, Li Li, Shibiao Liu, Qiaosheng Jiang, Kaiyu Ye, Faming Wang

“…Our results demonstrate that TCCA effectively inhibits Psa growth in vitro, even at low concentrations, with minimum inhibitory concentrations (MICs) of 20 mg/L (TCCA added directly to the Psa suspension) and 100 mg/L (Psa cells mixed with liquid LB medium before adding TCC). …”
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Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation by Syawal Abdurrahman, Ruslin Ruslin, Aliya N. Hasanah, Resmi Mustarichie, Mus Ifaya

“…The assay results showed that fractions F2 and F3 had a better effect on hair growth compared to the positive control, and the test compound obtained from the LC-MS analysis, bufotalinin, had a strong binding energy to the receptor in the molecular docking interaction study: −5.99 kcal/mol compared to −4.8 kcal/mol for minoxidil. …”
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Prospects of molecular genetic approaches in controlling technological properties of wheat grain in the context of the "grain – flour – bread" chain by E. K. Khlestkina, T. A. Pshenichnikova, N. I. Usenko, Yu. S. Otmakhova

“…Currently, along with the growth of grain production, the traditional range of staples is crowded out, the quality of most popular bread varieties deteriorates, and dozens of different substances of biological and chemical origin are used as bread improvers. …”
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Solar PV Minigrid Technology: Peak Shaving Analysis in the East African Community Countries by Jeanne Paula Ihirwe, Zibiao Li, Keyuan Sun, Samuel Bimenyimana, Chen Wang, Godwin Norense Osarumwense Asemota, Aphrodis Nduwamungu, Cicilia Kemunto Mesa

“…However, several other fundamental advances in the solar photovoltaic (PV) industry have emerged, and the developments have seen the sector experienced significant growth and diversification of models, regulation, and financing. …”
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BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia by Xu Sang, Yongping Zhang, Fang Fang, Li Gao, Yanfang Tao, Xiaolu Li, Zimu Zhang, Jianwei Wang, Yuanyuan Tian, Zhiheng Li, Di Yao, Yumeng Wu, Xinran Chu, Kunlong Zhang, Li Ma, Lihui Lu, Yanling Chen, Juanjuan Yu, Ran Zhuo, Shuiyan Wu, Zhen Zhang, Jian Pan, Shaoyan Hu

“…Recent studies have shown that as a novel BRD4 (bromodomain containing 4) PROTACs (proteolysis targeting chimeras) degrader, GNE-987 can slow down the growth of various tumors and increase apoptosis, with promising clinical prospects. …”
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Hypericum Perforatum-Derived Exosomes-Like Nanovesicles: A Novel Natural Photosensitizer for Effective Tumor Photodynamic Therapy by Ma X, Chen N, Zeng P, He Y, Zhang T, Lu Y, Li Z, Xu J, You J, Zheng Y, Wang L, Luo M, Wu J

“…PDT efficacy was assessed in vitro and in vivo.Results: HPDENs exhibited robust photosensitizing properties, generating reactive oxygen species (ROS) through both Type I and Type II pathways upon light activation. …”
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The Role of Platelet-Rich Plasma (PRP) in Enhancing IVF Success in Women With Ovarian Insufficiency: A Cohort Study by Zahra Mohammad Alipour, Farahnazsadat Ahmadi, Sina Mohajernoei, Roghaye Gharaei, Nazanin Hojjati, Elham Shirali, Firouzeh Akbari Asbagh

“…Platelet-Rich Plasma (PRP), rich in concentrated growth factors, has shown regenerative potential in various medical fields. …”
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Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain by Michaela Berankova, Jiri Holoubek, Vaclav Hönig, Zuzana Matusova, Martin Palus, Jiri Salat, Imtissal Krayem, Jarmila Vojtiskova, Pavel Svoboda, Veronika Pranclova, Lukas Valihrach, Peter Demant, Marie Lipoldova, Daniel Ruzek

“…Methods TBEV growth and the production of key cytokines and chemokines were measured and compared in macrophages derived from BALB/c, CcS-11, and STS mice. …”
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INNOVATIVE MECHANISMS FOR IMPLEMENTING STATE ECONOMIC POLICY FOR POST-WAR RECONSTRUCTION OF UKRAINE: QUANTUM TRANSFORMATIONS AS A DRIVER OF DEVELOPMENT by Oleksiy Shkuratov, Liudmila Antonova, Roman Dzyuba

“…The article emphasizes that quantum technologies are one of the key industries that can contribute to rapid economic growth and technological breakthrough. The quantum transformation of Ukraine's economy in the conditions of post-war recovery can become an important component of the state investment policy, which will stimulate innovative development and increase the country's competitiveness in the international arena. …”
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AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i> by Huan Liu, Huayu Lei, Juanjuan Cao, Zhaobang Xie, Yile Shi, Yanni Zhao

“…The deletion of <i>acfA</i> had no effect on bacterial growth but resulted in a significant reduction in biofilm formation, hemolytic activity, mucus adhesion, and the accumulated mortality of zebrafish, compared to the wild-type strain and the complementary strain <i>acfA</i>⁺. …”
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