Vision Improvement after Osimertinib Treatment in Paraneoplastic Optic Neuropathy Associated with Lung Adenocarcinoma by Masaomi Kubota, Nobumasa Tamura, Takaaki Hayashi, Euido Nishijima, Haruhiko Yanagisawa, Akira Kojima, Tadashi Nakano

“…Herein, we describe the clinical course of an older adult patient with PON whose loss of vision improved after switching between epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatments for cancer. …”
Get full text

Type II Diabetes Patients under Sildenafil Citrate: Case Series Showing Benefits and a Side Effect by Livia M. Zimmermann, Mauricio S. Baptista, João Paulo Tardivo, Maria A. Pinhal

“…Diabetes mellitus is a highly prevalent disease with rapid universal growth. In 2013, there were already 382 million people with diabetes, and it is expected that by 2035, this number will double. …”
Get full text

Leveraging on large language model to classify sentences: a case study applying STAGES scoring methodology for sentence completion test on ego development by Xavier Bronlet

“…Ego consists of the traits that influence how a person perceives and engages with the world, while ego development is a crucial aspect of adult personality growth, influencing behaviors and decisions in both personal and professional contexts. …”
Get full text

Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems by Teodosio Giacolini, Antonio Alcaro, David Conversi, Lorenzo Tarsitani

“…This refers to the slowing down of growth and development, resulting in both a prolonged period of dependence on a caring/protective adult and the persistence of juvenile characteristics throughout life. …”
Get full text

Combination therapy of intravitreal ranibizumab and sub-tenon triamcinolone for treatment of resistant diabetic macular edema: a clinical study in Egypt by Hossam Eldin M. A. Khalil, Hazem E. Haroun, Alaa A. I. Shalan, Waleed M. Mahran

“…This research was to examine the efficacy of sub-tenon steroid and anti- vascular endothelial growth factor (VEGF) injections as a combination therapy for the treatment of resistant DME, owing to the synergistic effect of this combination. …”
Get full text

Structural Properties, Cytotoxicity, and Anti-Inflammatory Activity of Silver(I) Complexes with tris(p-tolyl)Phosphine and 5-Chloro-2-Mercaptobenzothiazole by L. Kyros, N. Kourkoumelis, M. Kubicki, L. Male, M. B. Hursthouse, I. I. Verginadis, E. Gouma, S. Karkabounas, K. Charalabopoulos, S. K. Hadjikakou

“…The activity towards cell viability was 2>3>5>1>4, while the order of the inhibitory activity in cell growth proliferation follows the order, 2>3>1>4>5. …”
Get full text

Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting by Ming Liu, Li Zheng, Yang Zhang, Jinhui Tian

“…Abstract Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen and progesterone receptors, and lack of human epidermal growth factor receptor 2 (HER2) expression. Traditional Chinese medicine (TCM) has demonstrated promising efficacy in treating TNBC. …”
Get full text

Analysis of the 2016 – 2025 fiscal budget of U.S. Centers for Disease Control and Prevention by Nana LIU, Lieyu HUANG, Yuan DANG, Zekai YU, Qianqiu LIU, Yan GUO

“…ResultsThe total presidential budget of the CDC showed a fluctuating growth trend from 2016 to 2025, with the lowest value in 2018 (US$ 11.059 billion) and the highest value in 2023 (US$ 47.469 billion). …”
Get full text

Pharmacological Studies on the Antidiabetic, Antioxidant, and Antimicrobial Efficacies of Commiphora myrrha Resin in Streptozotocin-Induced Diabetes in Rats: A Preclinical Study by Rasha A. Mansouri, Aftab Ahmad, null Roushdy M. M., Huda F. Alshaibi, Mahmoud Ragab

“…The plant extract showed promising inhibition of the growth of gram-positive and gram-negative pathogens. …”
Get full text

Antimalarial Activity of Extract and Fractions of Sauropus androgynus (L.) Merr. by Wiwied Ekasari, Dwi Fatmawati, Siti M. Khoiriah, Wenda A. Baqiuddin, Hawi Q. Nisa, Adinda A. S. Maharupini, Tutik S. Wahyuni, Rice D. Oktarina, Eko Suhartono, Ram K. Sahu

“…In a prophylactic test, ethanolic extract showed parasite growth inhibitory activity of 67.74 ± 9.21% after the administration of 400 mg/kg body weight for 4 days before infection, and 65.30 ± 10.44% after the administration of 200 mg/kg body weight for 8 consecutive days (4 days before and after infection). …”
Get full text

ApWD40a, a Member of the WD40-Repeat Protein Family, Is Crucial for Fungal Development, Toxin Synthesis, and Pathogenicity in the Ginseng Alternaria Leaf Blight Fungus <i>Alternari... by Jinling Lan, Shengjie Mei, Yingxue Du, Meili Chi, Jiayi Yang, Shuliu Guo, Mingliang Chu, Ronglin He, Jie Gao

“…The deletion of <i>ApWD40a</i> impaired the mycelial growth, reduced the sporulation, and significantly decreased the efficiency in utilizing various carbon sources. …”
Get full text

Performance and intestinal health of piglets in the nursery phase subjected to diets with condensed black wattle (Acacia mearnsii) tannin by Kelly Lais de Souza, Cleandro Pazinato Dias, Marco Aurélio Callegari, André Friderichs, Alcides Oliver Sencio Paes, Rafael Humberto de Carvalho, Caio Abércio da Silva

“…Objective The objective of this study was to evaluate the use of condensed tannin from black acacia (Acacia mearnsii) as a substitute additive for zinc oxide and growth-promoting antibiotics on the performance, digestibility, and intestinal health of piglets in the nursery phase. …”
Get full text

Regional-scale precision mapping of cotton suitability using UAV and satellite data in arid environments by Jianqiang He, Yonglin Jia, Yi Li, Asim Biswas, Hao Feng, Qiang Yu, Shufang Wu, Guang Yang, Kadambot.H.M. Siddique

“…Reflectivity corrections in Sentinel-2A data notably improved RF model inversion accuracy (R² gains of 0.114–0.384). (3) Suitability Analysis: The cotton suitability index maps for 2022 and 2023 indicated that most fields in Tumushuke (TMSK) were moderately suitable for cotton growth, although some areas were unsuitable. This highlights the need for additional irrigation and targeted soil water and salt management to meet cotton requirements and reduce salinity risks. …”
Get full text

The Types of Religious Identity of Chechen Students by М. Т. Khaskhanova, M. V. Vereshchagina

“…In connection with the growth of religious consciousness of young people in Russia, the study of their religious identity is being updated. …”
Get full text

Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. by Dylan Carter-Cusack, Stephen Huang, Sahar Keshvari, Omkar Patkar, Anuj Sehgal, Rachel Allavena, Robert A J Byrne, B Paul Morgan, Stephen J Bush, Kim M Summers, Katharine M Irvine, David A Hume

“…The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor 1 receptor (Csf1r) gene (Csf1rko) severely compromises pre-weaning somatic growth and maturation of organ function. Transfer of wild-type bone marrow cells (BMT) at weaning rescues tissue macrophage populations permitting normal development and long-term survival. …”
Get full text

High, but variable prevalence of Sarcocystis cruzi infections in farm-raised American bison (Bison bison) beef destined for human consumption by Larissa S. de Araujo, Aditya Gupta, Marianne Dias Papadopoulos, Doaa Naguib, Jacquin Battle, Oliver Kwok, Asis Khan, Benjamin Rosenthal, Jitender P. Dubey

“…Sarcocystis cruzi (transmitted via canids) is recognized as the most pathogenic Sarcocystis species, causing abortion, low milk yield and poor body growth. It has been experimentally cross-transmitted from cattle to bison and vice versa. …”
Get full text

Screening of Probiotic Bacteria from Intestine and Culture Environment of Hoeven’s slender carp Leptobarbus hoeveni Blkr to Control Pathogenic Bacteria by . Sunarto, . Sukenda, . Widanarni

“…The result showed that probiotic bacteria inhibit the growth of Streptococcus iniae, Flexibacter columnaris, Mycobacterium fortuitum and Aeromonas hydrophila in vitro.  …”
Get full text

OPTIMIZATION OF ROCK PHOSPHATE USE AND EFFECT ON SOYBEAN GRAIN YIELD AND YIELD COMPONENTS ON AN ANDOSOL AND ACRISOL OF CAMEROON by Lawrence T. Nanganoa, Foncha Felix, Kamdem N. Franck Gilles, Djocne F. Christiane, Christopher Suh, Francis A. Ngome

“…Modulation of rock phosphate fertilizer dose in soybean cultivation is crucial for maximizing plant growth and grain yield while ensuring efficient use of resources and environmental sustainability. …”
Get full text

Demonstration Exam in Continuing Entrepreneurial Education within the VET and HE Systems by O. A. Romanova, K. V. Anisimova

“…Moreover, the specifics of the formation of entrepreneurial competencies in VET have not been studied, despite the steady growth in the share of college graduates in the university applicant base. …”
Get full text

Deformations and seepage-induced erosion of fractured rocks in fault under confined settings by Wenbin SUN, Dianjin TIAN, Cheng MA, Yanchao XUE, Can YANG, Kaipeng ZHU

“…The fitted curves of the lost mass of particles exhibited an exponential growth function with time, with the lost mass being inversely proportional to the confining axial stress. …”
Get full text