Integrative multiomics analysis reveals host-microbe-metabolite interplays associated with the aging process in Singaporeans by Liwei Chen, Tingting Zheng, Yifan Yang, Prem Prashant Chaudhary, Jean Pui Yi Teh, Bobby K. Cheon, Daniela Moses, Stephan C. Schuster, Joergen Schlundt, Jun Li, Patricia L. Conway

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From microbes to molecules: unveiling host-microbe interactions with spatial metabolomics by Malin Stüwe, Lars-Erik Petersen, Manuel Liebeke

“…These approaches not only provide molecular insights they also highlight the need of integrating activity measurements and temporal analyses to capture the dynamic nature of microbial assemblages. …”
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An anaerobic in vitro flow model for studying interactions at the gastrointestinal host–microbe interface by L. L. Bang, J. S. Pettersen, N. Høiland, A. M. Rojek, D. R. Tornby, J. Møller-Jensen, U. S. Justesen, R. M. Pedersen, T. E. Andersen

“…Abstract In vitro research on host–microbe interactions in the human gut has been challenging due to the differing oxygen requirements of mammalian cells and intestinal microbiota. …”
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Stool multi-omics for the study of host–microbe interactions in inflammatory bowel disease by Consuelo Sauceda, Charlie Bayne, Khadijeh Sudqi, Antonio Gonzalez, Parambir S. Dulai, Rob Knight, David J. Gonzalez, Carlos G. Gonzalez

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An interactive art activity to promote student reflection and learning about host-microbe interactions by Camila Souza Beraldo

“…To explore how different factors shape host–microbe interactions, I developed the activity MicrobiART, which uses mixed art materials to create analogies that illustrate the dynamic relationships between hosts, microbes, and their environments. …”
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Protocol for predicting host-microbe interactions and their downstream effect on host cells using MicrobioLink by Lejla Gul, Anna Julia Elias, Tanvi Tambaku, Marton Olbei, Emily Watters, Balazs Bohar, Dezso Modos, Matthew Madgwick, Tamas Korcsmaros

“…Summary: Analyzing host-microbe interactions is essential for understanding how microbiota changes disrupt host homeostasis. …”
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Cross-matrix multi-omics profiling identifies host–microbe interactions and diagnostic signatures in bovine subclinical mastitis by Yuqiong Li, Xiulan Xie, Youli Yu, Song Hua, ZhuMing Zhang, Zhengwei Zhao, Haihui Gao, Chenglian Zhang, Meizhou Huang

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Evolutionary history and association with seaweeds shape the genomes and metabolisms of marine bacteria by Catherine A. Pfister, Johanna Berlinghof, Maximiliana Bogan, Ulisse Cardini, Angélique Gobet, Pauline Hamon-Giraud, Jessica Hart, Natalia Jimenez, Anne Siegel, Emma Stanfield, Marine Vallet, Catherine Leblanc, Coralie Rousseau, François Thomas, Willem Stock, Simon M. Dittami

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Advances in intestinal epithelium and gut microbiota interaction by Sen Yang, Sen Yang, Hanmin Liu, Hanmin Liu, Hanmin Liu, Hanmin Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu

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An in vitro model demonstrating homeostatic interactions between reconstructed human gingiva and a saliva-derived multispecies biofilm by Lin Shang, Sanne Roffel, Vera Slomka, Eleanor M. D’Agostino, Aline Metris, Mark J. Buijs, Bernd W. Brandt, Dongmei Deng, Susan Gibbs, Bastiaan P. Krom

“…Abstract Background In the oral cavity, host-microbe interactions (HMI) continuously occur and greatly impact oral health. …”
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Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism by Boram Seo, Mi Young Lim

“…The gut microbiota maintains host health and shapes immune responses through intricate host-microbe interactions. Bacterial flagellin, a key microbe-associated molecular pattern, is recognized by Toll-like receptor 5 (TLR5) and NOD-like receptor family caspase activation and recruitment domain-containing 4 inflammasome. …”
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Disrupted host-microbiota crosstalk promotes nonalcoholic fatty liver disease progression by impaired mitophagy by Wenjing Yin, Wenxing Gao, Yuwei Yang, Weili Lin, Wanning Chen, Xinyue Zhu, Ruixin Zhu, Lixin Zhu, Na Jiao

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Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome by Hsiao-Wen Huang, Tzu-Chien Kuo, Tzu-Chien Kuo, Ya-Jane Lee, Ya-Jane Lee, Ming-Ju Chen, Ming-Ju Chen

“…These preliminary, hypothesis-generating results highlight the value of multi-omics approaches for understanding host-microbe interactions and support further investigation into personalized probiotic strategies as potential adjuvant therapies in feline CKD.…”
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Circadian rhythms of gut microbiota and plaque vulnerability: mechanisms and chrono-microbiota modulation interventions by Taiyu Zhai, Xueyang Zou, Zichen Zhang, Yifei Wang, Lin Shi, Wenbo Ren, Jing Huang

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Multi-omics data integration reveals metabolome as the top predictor of the cervicovaginal microenvironment. by Nicholas A Bokulich, Paweł Łaniewski, Anja Adamov, Dana M Chase, J Gregory Caporaso, Melissa M Herbst-Kralovetz

“…Emerging evidence suggests that host-microbe interaction in the cervicovaginal microenvironment contributes to cervical carcinogenesis, yet dissecting these complex interactions is challenging. …”
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mSphere of Influence: The integral art of resolving host-virus interactions by Elliott D. SoRelle

“…Chiu et al. (Cell Host Microbe 14:607–618, 2013, 10.1016/j.chom.2013.11.009), and “Comprehensive integration of single-cell data” by T. …”
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Integrated Microbiome–Metabolome Analysis Reveals Intestine–Liver Metabolic Associations in the Moustache Toad by Shui-Sheng Yu, Jing-Wen Xiang, Lin Zhang, Xiao-Hua Guo, Yu Wang, Guo-Hua Ding, Hua-Li Hu

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Integrating multi-omics data to reveal the host-microbiota interactome in inflammatory bowel disease by Fengyuan Su, Meng Su, Wenting Wei, Jiayun Wu, Leyan Chen, Xiqiao Sun, Moyan Liu, Shiqiang Sun, Ren Mao, Arno R. Bourgonje, Shixian Hu

“…However, the precise mechanisms behind host-microbe cross-talk remain largely undefined, due to the complexity of the human intestinal ecosystem and multiple external factors. …”
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Impacts of prenatal nutrition on metabolic pathways in beef cattle: an integrative approach using metabolomics and metagenomics by Guilherme Henrique Gebim Polizel, Wellison J. S. Diniz, Aline Silva Mello Cesar, German D. Ramírez-Zamudio, Angela Cánovas, Evandro Fernando Ferreira Dias, Arícia Christofaro Fernandes, Barbara Carolina Teixeira Prati, Édison Furlan, Gabriela do Vale Pombo, Miguel Henrique de Almeida Santana

“…Abstract Background This study assessed the long-term metabolic effects of prenatal nutrition in Nelore bulls through an integrated analysis of metabolome and microbiome data to elucidate the interconnected host-microbe metabolic pathways. …”
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O-GlcNAc transferase plays dual antiviral roles by integrating innate immunity and lipid metabolism by Hong Dong, Chenxi Liang, Junjie Zhang, Weidong Wu, Nitesh Kumar, Zihao Liu, Yajun Sun, Zhiwei Liao, Xiaolin Cheng, Yanbao Yu, Yong Zhang, Michael J. Holtzman, Jianrong Li, Kymberly M. Gowdy, Paul G. Thomas, Jovica D. Badjic, Anjun Ma, Qin Ma, Jacob S. Yount, Shan-Lu Liu, Haitao Wen

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