Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade by Yo-Ting Tsai, Jeffrey Schlom, Renee N. Donahue

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Influence of Corn (Zea mays L.) Cultivar Development on Grain Nutrient Concentration by Carla Fernanda Ferreira, Antônio Carlos Vargas Motta, Stephen A. Prior, Carlos Bruno Reissman, Nicolas Z. dos Santos, Juarez Gabardo

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Development and application of decontamination methods for the re-use of laboratory grade plastic pipette tips. by Sang Hyuk Lee, William Kastor, Xiao Fu, Vikas Soni, Michael Keidar, Marc Donohue, Steve Wood, Enusha Karunasena

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Magnetic Anisotropy Dominates over Physical and Magnetic Structure in Performance of Magnetic Nanoflowers by Julie Borchers, Kathryn Krycka, Brianna Bosch‐Santos, Eduardo de Lima Correa, Anirudh Sharma, Hayden Carlton, Yanliu Dang, Michael Donahue, Cordula Grüttner, Robert Ivkov, Cindi L. Dennis

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Airborne lidar intensity correction for mapping snow cover extent and effective grain size in mountainous terrain by Chelsea Ackroyd, Christopher P. Donahue, Brian Menounos, S. McKenzie Skiles

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Effect of acupoint application of Traditional Chinese Medicine on recovery of gastrointestinal function after cesarean section (中药穴位敷贴促进剖宫产术后胃肠功能恢复的效果观察)... by PENG Rufeng (彭茹凤), LI Fengmin (黎凤民), HUANG Ling (黄翎), HUANG Huan (黄环), SU Qiumei (苏秋梅)

“…Conclusion TCM acupoint application on Shenque (CV 8), bilateral Yongquan (KI 1), bilateral Shenshu(BL 23) is effective on recovery of puerperae’s gastrointestinal function, reduce the risk of abdominal distension and improve postpartum quality of life. …”
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Construction of a Novel Necroptosis-Related Signature in Rat DRG for Neuropathic Pain by Liu Y, Hao S, Hao H, Zheng G, Bing J, Kang L, Li J, Zhao H, Hao H

“…Yang Liu,1 Shikang Hao,2 Hongyu Hao,3 Guona Zheng,1 Jie Bing,1 Lin Kang,1 Jia Li,4 Huanfen Zhao,1,* Han Hao5,* 1Department of Pathology, Hebei General Hospital, Shijiazhuang, People’s Republic of China; 2The First Clinical Medical School, Shanxi Medical University, Taiyuan, People’s Republic of China; 3Department of Neurology, Hebei General Hospital, Shijiazhuang, People’s Republic of China; 4Outpatient Department, Hebei Medical University, Shijiazhuang, People’s Republic of China; 5Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, Ministry of Education, The Key Laboratory of New Drug Pharmacology and Toxicology, Center of Innovative Drug Research and Evaluation, Hebei Medical University, Shijiazhuang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Han Hao; Huanfen Zhao, Email 18800790@hebmu.edu.cn; ZHAO552588@126.comBackground: Recent studies have shown necroptosis may play a role in the development of inflammation-associated pain. …”
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miR-21 Overexpression Promotes Esophageal Squamous Cell Carcinoma Invasion and Migration by Repressing Tropomyosin 1 by Zhuojian Shen, Xia Xu, Liangzhan Lv, Honglue Dai, Ju Chen, Baishen Chen

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Prediction of Pathologic Response in Unresectable Hepatocellular Carcinoma After Downstaging with Locoregional and Systemic Combination Therapy by Yang C, Chen Y, Sheng L, Wang Y, Zhang X, Yang Y, Ronot M, Jiang H, Song B

“…Chongtu Yang,1,2,* Yidi Chen,1,2,* Liuji Sheng,1,2 Yanshu Wang,1,2 Xiaoyun Zhang,3 Yang Yang,4 Maxime Ronot,5 Hanyu Jiang,1,2 Bin Song1,2,6 1Department of Radiology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3Division of Liver Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 4Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 5Department of Radiology, Hôpital Beaujon (Université de Paris), Clichy, France; 6Department of Radiology, Sanya People’s Hospital, Sanya, Hainan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hanyu Jiang; Bin Song, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Email hanyu_jiang@foxmail.com; songlab_radiology@163.comBackground: The combination of locoregional and systemic therapy may achieve remarkable tumor response for unresectable hepatocellular carcinoma (HCC).Objective: We aimed to investigate the correlation between radiologic and pathologic responses following combination therapy, evaluate their prognostic values, and to establish a non-invasive prediction system for pathologic response.Methods: This single-center retrospective study included 112 consecutive patients with HCC who underwent locoregional and systemic combination therapy followed by liver resection or transplantation. …”
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Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide by Xie Y, Zhu M, Bao H, Chen K, Wang S, Dai J, Chen H, Li H, Song Q, Wang X, Yu L, Pei J

“…Yizhuo Xie,1 Ming Zhu,1 Han Bao,1 Kejia Chen,1 Shanshan Wang,1 Jingwen Dai,1 Hongzhu Chen,1 He Li,1 Qi Song,2 Xinlu Wang,2 Liangping Yu,2 Jin Pei1 1Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People’s Republic of China; 2Department of Clinical Pharmacy, the First Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jin Pei, Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, People’s Republic of China, Tel +86-431-85619725, Email peijin@jlu.edu.cn Liangping Yu, Department of Clinical Pharmacy, the First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130061, People’s Republic of China, Tel +86 431 81879802, Email liangpingyu@jlu.edu.cnPurpose: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. …”
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The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial by Elena Giudice, Tzu-Ting Huang, Jayakumar R. Nair, Grant Zurcher, Ann McCoy, Darryl Nousome, Marc R. Radke, Elizabeth M. Swisher, Stanley Lipkowitz, Kristen Ibanez, Duncan Donohue, Tyler Malys, Min-Jung Lee, Bernadette Redd, Elliot Levy, Shraddha Rastogi, Nahoko Sato, Jane B. Trepel, Jung-Min Lee

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Mechanism of Acupuncture Therapy on RANKL/OPG Signaling Pathway to Regulate Bone Metabolism Balance in Osteoporosis Model Rats by Qin YIN, Hong PAN, Xiaojuan DING, Xiaoguang QIN, Xiaorong GUO

“…The rats in the blank group and the model group were given 0.9%NaCl solution for 50 μg/(kg·d)by gavage, the estradiol group was given estradiol valerate 50 μg/(kg·d)by gavage, the acupuncture group was given electroacupuncture at Shenshu, Sanyinjiao, Guanyuan, Zusanli acupoints with stimulation intensity of 2 mA, frequency of 2 Hz, 15 min/time, once a day. …”
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Rethinking the residual approach: leveraging statistical learning to operationalize cognitive resilience in Alzheimer’s disease by Colin Birkenbihl, Madison Cuppels, Rory T. Boyle, Hannah M. Klinger, Oliver Langford, Gillian T. Coughlan, Michael J. Properzi, Jasmeer Chhatwal, Julie C. Price, Aaron P. Schultz, Dorene M. Rentz, Rebecca E. Amariglio, Keith A. Johnson, Rebecca F. Gottesman, Shubhabrata Mukherjee, Paul Maruff, Yen Ying Lim, Colin L. Masters, Alexa Beiser, Susan M. Resnick, Timothy M. Hughes, Samantha Burnham, Ilke Tunali, Susan Landau, Ann D. Cohen, Sterling C. Johnson, Tobey J. Betthauser, Sudha Seshadri, Samuel N. Lockhart, Sid E. O’Bryant, Prashanthi Vemuri, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley

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Idiopathic Retroperitoneal Fibrosis-Related Hydronephrosis: Evaluation of Comprehensive Management and Prediction of Inflammatory Markers for Stent-Free Outcomes by Huang Z, Liu Y, Xiao Y, Hu H, Xu T

“…Zixiong Huang,1– 3 Yanying Liu,4,5 Yunshu Xiao,5 Hao Hu,1,2 Tao Xu1,2 1Department of Urology, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China; 2Applied Lithotripsy Institute, Peking University, Beijing, 100044, People’s Republic of China; 3Department of Urology, Michigan Medicine, Ann Arbor, MI, 48109, USA; 4Department of Rheumatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 5Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, 100044, People’s Republic of ChinaCorrespondence: Hao Hu; Tao Xu, Department of Urology, Peking University People’s Hospital, 11 Xizhimen South Street, Beijing, 100044, People’s Republic of China, Email huhao@bjmu.edu.cn; xutao@pkuph.edu.cnObjective: This study investigated the efficacy of comprehensive management and predictable inflammatory markers for idiopathic retroperitoneal fibrosis (iRPF)-related hydronephrosis outcomes.Methods: Patients with iRPF-related hydronephrosis underwent surgical (ureteral stent and/or nephrostomy tube placement) and medical (corticosteroid-based multiple immunosuppressants) management were classified according to stent-indwelling outcomes. …”
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Prospective Single-Arm Study of Remifentanil-Propofol Anesthesia with Manual Right Hypochondrial Compression for Painless Gastroscopy in Obese Patients by Wang M, Tang J, Pan Z, Jiang H, Hu D, Zhu B, Liang Z, Zhao X, Li Y

“…Mengxia Wang,1,* Jieke Tang,1,* Zhaojie Pan,2 Hongxue Jiang,1 Donghua Hu,1 Beibei Zhu,2 Zhaojia Liang,1 Xiangfeng Zhao,1 Yalan Li1 1Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China; 2Department of Digestive Endoscopy Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yalan Li, Department of Anesthesiology, The First Affiliated Hospital of Jinan University, No. 613, Huangpu West Avenue, Tianhe District, Guangzhou, Guangdong Province, 510630, People’s Republic of China, Email tyalan@jnu.edu.cnPurpose: The provision of comfortable and safe environment for painless gastroscopy in obese patients is an urgent clinical problem. …”
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Angiogenesis Regulated by Electroacupuncture Combined with Rehabilitation Training in Cerebral Ischemia Involved in PI3K/Akt Signaling Pathway by Wenchao YAO, Mengxing LI, Qing LIU, Mingyue TONG, Peng HE, Wei TANG

“…The combined acupuncture group was given electroacupuncture at acupoints of Baihui, Fengfu, Xinshu and Neiguan, and treadmill training 4 hours after operation, once a day for 14 days. …”
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