Prevalence and determinants of unintended pregnancy among rural reproductive age women in Ethiopia by Melak Jejaw, Kaleb Assegid Demissie, Misganaw Guadie Tiruneh, Kaleab Mesfin Abera, Yawkal Tsega, Abel Endawkie, Wubshet D. Negash, Amare Mesfin Workie, Lamrot Yohannes, Mihret Getnet, Nigusu Worku, Adina Yeshambel Belay, Lakew Asmare, Hiwot Tadesse Alemu, Demiss Mulatu Geberu, Asebe Hagos

“…Abstract Despite growing utilization of family planning in Ethiopia, many pregnancies in rural areas are still unintended and unintended pregnancy remains a major global challenge in public and reproductive health, with devastating impact on women and child health, and the general public. Hence, this study was aimed to determine the prevalence and associated factors of unintended pregnancy in rural women of Ethiopia. …”
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Thrombolytic therapy for patients with acute ischemic stroke: systematic review and network meta-analysis of randomized trials by Li-Chao-Yue Sun, Wen-Shu Li, Wei Chen, Zhao Ren, Chun-Xing Li, Ze Jiang, Le Wang, De-Li Wang, Qing Xie

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Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact by Enrique Mondragon-Estrada, Jane W. Newburger, Steven R. DePalma, Martina Brueckner, John Cleveland, Wendy K. Chung, Bruce D. Gelb, Elizabeth Goldmuntz, Donald J. Hagler, Jr., Hao Huang, Patrick McQuillen, Thomas A. Miller, Ashok Panigrahy, George A. Porter, Jr., Amy E. Roberts, Caitlin K. Rollins, Mark W. Russell, Martin Tristani-Firouzi, P. Ellen Grant, Kiho Im, Sarah U. Morton

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An open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome by Tess Levy, J. Lloyd Holder, Jr., Joseph P. Horrigan, Michael F. Snape, Alison McMorn, Christina Layton, Hailey Silver, Kate Friedman, Hannah Grosman, Slayton Underwood, Danielle Halpern, Jessica Zweifach, Paige M. Siper, Alexander Kolevzon

“…AMO-01 was well tolerated, with no serious adverse events (AEs) reported. All AEs were mild or moderate in severity. Seizures were reduced by at least 25% compared to baseline at each follow-up (weeks 1, 2, and 4). …”
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Glucose Metabolism Changes in Patients with Chronic Hepatitis C Treated with Direct Acting Antivirals by Sylvia Drazilova, Martin Janicko, Lubomir Skladany, Pavol Kristian, Marian Oltman, Maria Szantova, Dusan Krkoska, Eva Mazuchova, Lubica Piesecka, Veronika Vahalova, Marek Rac, Ivan Schreter, Ladislav Virag, Tomas Koller, Adriana Liptakova, Miriam Ondrasova, Peter Jarcuska

“…The decrease was also visible in treatment experienced patients and patients with Child-Pugh A cirrhosis. Conclusion. We confirmed that the prevalence of either T2DM or IFG increases in chronic hepatitis C patients with the degree of fibrosis. …”
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Health literacy assessment and analysis of influencing factors in pregnant women with gestational diabetes mellitus in Southwest China by Fangmei Tang, Fangmei Tang, Li Gu, Li Gu, Xiujing Guo, Xiujing Guo, Wenjing Fu, Wenjing Fu, Benyi He, Yuqing Song, Yuqing Song, Dehua Li, Dehua Li

“…Given that the HLS-14 has not been used in GDM previously, its reliability and validity testing was included as a secondary objective.MethodIt was a cross-sectional survey with 565 GDM pregnancies. The Maternal and child health information access questionnaire, Chinese version of the HLS-14, Perceived Social Support Scale (PSSS) and General Self-efficacy Scale (GSES) was used to collect health information access behaviors, health literacy, social support and self-efficacy levels, respectively. …”
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Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infect... by Dana Unninayar, Emilia L. Falcone, Hugo Chapdelaine, Donald C. Vinh, Karina A. Top, Beata Derfalvi, Thomas B. Issekutz, Hélène Decaluwe, Anne Pham-Huy, Julia Upton, Stephen D. Betschel, Tamar Rubin, Sneha Suresh, Nicola A. M. Wright, Luis Murguía-Favela, Tatiana Kalashnikova, Lisa Barrett, Sharon Oldford, Marc-Andre Langlois, Corey Arnold, Manish Sadarangani, Tinghua Zhang, Tim Ramsay, Dina Yazji, Juthaporn Cowan, Juthaporn Cowan

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Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti... by Hui Luo, Jianhua Chen, Cao Li, Tian Wu, Siyue Yin, Guangping Yang, Yipin Wang, Zhihan Guo, Saifei Hu, Yanni He, Yingnan Wang, Yao Chen, Youqiang Su, Congxiu Miao, Yun Qian, Ruizhi Feng

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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

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Prevalence of overweight and obesity among preschool children in Hainan: a cross-sectional study in China's largest free-trade zone by Wei-Jia Wu, Wei-Jia Wu, Ping-Hao Chen, Ping-Hao Chen, Zhen-Ning Huang, Zhen-Ning Huang, Xue-Lu Lei, Xue-Lu Lei, Chen Wang, Chen Wang, Chun-hui Zhang, Chun-hui Zhang, Ping Wang, Ping Wang, Chui-can Huang, Qing Luo, Qing Luo, Li-Chun Fan, Li-Chun Fan

“…We recorded the height and weight of each child and calculated their body mass index (BMI). …”
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Breastfeeding support as predictors of sustainable breastfeeding practices of nursing mothers with common mental disorders in tertiary hospital nurseries in Nigeria: a cross sectio... by Michael Abel Alao, Olayinka Rasheed Ibrahim, Sakiru Abiodun Yekinni, Sikirat Adetoun Sotimehin, Udochukwu Michael Diala, Datonye Christopher Briggs, Aishatu Zaidu Musa, Zainab Oluwatosin Imam, Esther Oluwatoyin Famutimi, Adedeji Abiodun Idris, Adaeze C. Ayuk, Kenechukwu Kosisochukwu Iloh, Chioma Laura Odimegwu, Ayomide Toluwanimi Adeyemi, Patricia F. Medupin, Yetunde C. Adeniyi, Kenechi Ogbodo Nnamani, Olukemi Oluwatoyin Tongo

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Impact de l’évaluation de la sédation sur la durée de ventilation mécanique en réanimation pédiatrique [Impact of sedation assessment on duration of mechanical ventilation in pedia... by Zakaria Zoheir Addou, Nabil Tabet Aoul, Abdessamad DALI ALI Dali-Ali

“…The CB score at the "after" phase was adequate sedation in (71.1%); mild sedation (16.9%) and deep sedation (12%). The duration of mechanical ventilation was 5,9±2,9 days without assessment versus 3,4±1,5 days after assessment. …”
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Kur’an Çerçevesinde Zıtlık (التضاد) İlişkileri by Gülhan Türk

“…Anlam ilişkileri aynı zamanda dilde kullandığımız lafızlar arasındaki Farklılıkları sınırlandırır ve bir ifadenin anlamına dair bütünlük sağlar. …”
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A PCR-independent, annealing-free cloning method for the insertion of short DNA fragments by Li Linbo, Yan Jin, Qi Yuan, Xiang Zhenglong, Jiang Na, Yuan Tongkang, Wang Zhenyi, Wang Yuan, Zhan Huaizhe, Liu Shiyi, Zhao Li, Xu Jing, Lei Xiaowei, Liu Yuxuan, Wang Gui, Xie Jiayang, Guo Zhenming, Cai Chunhai, Bian Shan

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Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shuntResearch in context by Binlin Da, Huan Chen, Wei Wu, Wuhua Guo, Anru Zhou, Qin Yin, Jun Gao, Junhui Chen, Jiangqiang Xiao, Lei Wang, Ming Zhang, Yuzheng Zhuge, Feng Zhang

“…Findings: A total of 400 patients in our cohort were included (median age and interquartile range, 59 (50, 66); 240 men). Two hundred and eighty patients made up the training set and 120 were in the testing set, and 346 patients were included in the external validation cohort. …”
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Longitudinal analysis of lifestyle risk factors, nutrition status and drivers of food choice among urban migrants in Ulaanbaatar, Mongolia, and Almaty, Kazakhstan: a formative stud... by Sabri Bromage, Shamil Tazhibayev, Xin Zhou, Chang Liu, Enkhtsetseg Tserenkhuu, Oksana Dolmatova, Munkhbat Khishignemekh, Leyla Musurepova, Wusigale, Soninkhishig Tsolmon, Enkhjargal Tsendjav, Davaasambuu Enkhmaa, Rajesh Kumar Rai, Bayarmaa Enkhbat, Bilige Menghe, Davaasambuu Ganmaa

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Multi-institutional evaluation comparing guidance from International Ki67 Working Group vs National Health Commission of China on immunohistochemistry-based Ki67 assessment alongsi... by Yin Wang, Jiarui Zou, Qinghua Cao, Guihong Dai, Panhong Fan, Xue Gong, Jinyan Jiang, Yanqing Kong, Chao Liu, Chunhui Liu, Chenjia Lu, Meiren Li, Zhiqiang Lang, Yang Lin, Yan Peng, Haiyan Shi, Yuhuan Wang, Jiu Wang, Bichen Xie, Bing Yang, Guohua Yu, Cuiping Zhang, Hengming Zhang, Luting Zhou, Zilan Zhang, Zhenli Zhu, Junmei Hao

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Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study by Dehao Chen, Dehao Chen, Sarah Lindley McKune, Sarah Lindley McKune, Yang Yang, Ibsa Aliyi Usmane, Ibsa Abdusemed Ahmed, Jafer Kedir Amin, Abdulmuen Mohammed Ibrahim, Abadir Jemal Seran, Nurmohammad Shaik, Amanda Ojeda, Bahar Mummed Hassen, Loic Deblais, Belisa Usmael Ahmedo, Kedir Abdi Hassen, Mussie Bhrane, Xiaolong Li, Nitya Singh, Kedir Teji Roba, Nigel P. French, Gireesh Rajashekara, Mark J. Manary, Jemal Yusuf Hassen, Arie Hendrik Havelaar, on behalf of the CAGED Research Team

“…While additional research is needed to investigate whether findings from this study are replicable in other populations, community efforts to improve infant and young child feeding practices and food hygiene, and water, sanitation, and hygiene (WaSH) at the household level, could reduce (cross-)contamination at the point of exposure.…”
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Simulation-based training program effect on pediatric nurses’ knowledge and performance regarding heel-prick during newborn blood screening test by Abdulaziz Asiri, Abeer A. Almowafy, Shimaa M. Moursy, Hanan A. Abd-Elhay, Shimaa Abdelrahim Khalaf Ahmed, Aml S. Abdelrahem, Marim T. Abo Seif, Faransa A. Ahmed

“…It is used in pediatric nursing training to allow nurses to practice and improve their clinical and conversational skills during an actual child encounter. A heel-prick is a complex psychomotor task that requires skill and knowledge from the pediatric nurse performing the procedure while applying for the National Newborn Screening Program. …”
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy by Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

“…Co-expression with G256W dominantly suppressed conduction by wild-type subunits in heterologous cells. Ezogabine partly reversed this suppression. …”
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