A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice by Peng Ma, Rongrong Huang, Yu Ou

“…In vivo, SGP8 lowered plasma alanine aminotransferase (ALT) and low density lipoprotein (LDL) content, normalized hepatic superoxide dismutase (SOD) and malondialdehyde (MDA) production, and reduced the severity of liver inflammation. …”
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İslam Medeniyetinin İlk Toplumsal Normlarının Oluşması Bağlamında Hz. Peygamber’in Biatleri by Abdulaziz Kıranşal

“…Zira Kur’an ayetlerinin büyük bir bölümünün henüz nazil olmadığı İslam’ın ilk yıllarında gerçekleşen biatlerdeki ana maddeler, Allah’a, Peygamber’e ve ahirete iman gibi inanç esaslarının yanında İslam medeniyetinin ana ilkelerini oluşturan ahlaki ve sosyal prensipleri de barındırmıştır. …”
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Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease by Yihuai He, Jinlian Jiang, Lili Ou, Yunfen Chen, Aikedaimu Abudukeremu, Guimei Chen, Weiwei Zhong, Zhigang Jiang, Nuerbiye Nuermaimaiti, Yaqun Guan

“…Mechanistically, during hepatic steatosis, altered lipid profiles exhibited lipotoxicity, inducing hepatocyte apoptosis and necroptosis, whereas endoplasmic reticulum (ER) stress triggered lipid remodeling processes similar to those observed in MASLD. …”
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Oral Supplementation with Three Vegetable Oils Differing in Fatty Acid Composition Alleviates High-Fat Diet-Induced Obesity in Mice by Regulating Inflammation and Lipid Metabolism by Waleed Aldamarany, Huang Taocui, Deng Liling, Yang Wanfu, Geng Zhong

“…Our findings showed that oral supplementation with all three oils for 8 weeks significantly reduced body weight, tissue weight, insulin resistance index, serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and free fatty acids (FFA), and markedly alleviated hyperglycemia, hyperlipidemia, and hepatic steatosis in obese mice. It also decreased leptin, pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, and (IL)-1beta (IL-1β), and increased anti-inflammatory adipokine adiponectin at both secretion and mRNA expression levels in the epididymal adipose tissue (EAT). …”
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TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization by Ken Zhao, Anita Karimi, Luke Kelly, Elena Petre, Brett Marinelli, Erica S. Alexander, Vlasios S. Sotirchos, Joseph P. Erinjeri, Anne Covey, Constantinos T. Sofocleous, James J. Harding, William Jarnagin, Carlie Sigel, Efsevia Vakiani, Etay Ziv, Hooman Yarmohammadi

“…Competing risk analysis showed a shorter time to local hepatic progression (at the site of the previously treated tumor) after TAE in patients with TP53-mutant HCC. …”
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Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy by Martín Muñoz-Ortega, Noé Macías-Segura, Javier Ventura-Juárez, Manuel Enrique Ávila-Blanco, Leonardo D. Ponce-Damian, Daniel González-Blas, Esperanza Sánchez-Alemán, Andrés Quintanar-Stephano

“…Liver diseases, including cirrhosis, viral hepatitis, and hepatocellular carcinoma, account for approximately two million annual deaths worldwide. …”
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Hepatokine leukocyte cell‐derived chemotaxin 2 as a biomarker of insulin resistance, liver enzymes, and metabolic dysfunction‐associated steatotic liver disease in the general popu... by Keita Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Yumie Takeshita, Hisanori Goto, Yujiro Nakano, Reina Yamamoto, Hiroaki Takayama, Atsushi Tajima, Tatsuya Yamashita, Masao Honda, Hiroyuki Nakamura, Toshinari Takamura

“…B‐mode ultrasonography was used to assess hepatic steatosis. Results The mean age and body mass index (BMI) of participants were 63.5 ± 10.2 years and 23.0 ± 3.1 kg/m2, respectively. …”
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An Analytical Perspective on Determination of Free Base Nicotine in E-Liquids by Vinit V. Gholap, Rodrigo S. Heyder, Leon Kosmider, Matthew S. Halquist

“…A Liquid-Liquid Extraction was carried out using toluene or hexane as extraction solvent. The Liquid-Liquid Extraction technique was found to be limited by solvent interactions with flavors. …”
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High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor? by Stian Magnus Staurung Orlien, Tekabe Abdosh Ahmed, Nejib Yusuf Ismael, Nega Berhe, Trine Lauritzen, Svein Gunnar Gundersen, Asgeir Johannessen

“…Case series have found markers of autoimmune hepatitis in patients with khat-related liver disease, suggesting that khat chewing might trigger an autoimmune response. …”
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Ameliorated Impact of Fenugreek Seed Extract on Some Blood Cellular and Biochemical Parameters in Female Albino Rats Exposed to Lead Acetate by Rozhya Abduljalil Naser, Rabar Yousif Mameik, Nazar M. Shareef Mahmood, Kurdo Bapir Chato

“…It has a several diverse-organ toxicant effect in various healthy issues included diseases of the hepatic, renal, and other body systems. Fenugreek seeds (Trigonella foenum graecum L.) were used in curing medicine and as food supplement since ancient times. …”
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Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis... by P. S. Demenkov, E. A. Antropova, A. V. Adamovskaya, E. I. Mishchenko, T. M. Khlebodarova, T. V. Ivanisenko, N. V. Ivanisenko, A. S. Venzel, I. N. Lavrik, V. A. Ivanisenko

“…Aberrant gene methylation, along with hepatitis C virus (HCV) infection, are important risk factors for the development of hepatocellular carcinoma. …”
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Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD) by Harshavardhan Rao B, Priya Nair, Anoop K. Koshy, S. Krishnapriya, C. R. Greeshma, Rama P. Venu

“…Each patient was carefully followed up for development of decompensation events such as new-onset/worsening ascites, hepatic encephalopathy, or variceal bleed during follow-up. …”
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The Association Between Serum Gamma‐Glutamyl Transferase and Gastrointestinal Cancer Risk: A Systematic Review and Meta‐Analysis by Alireza Ramandi, Jacob George, Amir Hossein Behnoush, Alireza Delavari, Zahra Mohammadi, Hossein Poustchi, Reza Malekzadeh

“…Conclusion Higher GGT levels correlate with higher rates of GI cancer incidence, especially in colorectal and hepatic cancers. Future studies should investigate this biomarker's potential role in risk assessment for digestive cancers.…”
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3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

“…In this research, we developed a 3D bioprinting method using gelatin methacryloyl (GelMA) hydrogel to fabricate lobule-like hepatorganoids, which faithfully mimic the structure of hepatic lobules with lower level of hypoxia (lobule vs 60°, 90°, control; 0.4880 vs 1.009, 0.6778, 0.8704; p < 0.01), high secretion of albumin (lobule vs 60°, 90°, control; 13.47 vs 12.39, 12.65, 10.08 mg/L; p < 0.01) and urea (lobule vs 60°, 90°, control; 5.304 vs 5.233, 4.781, 4.358 mg/L; p < 0.01) in vitro; and promotion of angiogenesis and maintenance of activity following orthotopic implantation. …”
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The Effect of Puncture Sites of Portal Vein in TIPS with ePTFE-Covered Stents on Postoperative Long-Term Clinical Efficacy by Si-liang Chen, Peng Hu, Zhi-peng Lin, Jian-bo Zhao

“…The Kaplan-Meier analysis was performed to assess the effect of different puncture sites on primary patency, the incidence of hepatic encephalopathy (HE), and survival. Results. …”
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Insights into the toxic impact of long-term exposure to diethyl phthalate on commercially important species Catla (Labeo catla) by Satabdi Ganguly, Basanta Kumar Das, Anupam Adhikari, Subir Kumar Nag

“…This led to an increase in circulating sex steroids E2 (41.62%) and 11 KT (24.59%) and eventually triggered hepatic Vtg production (23.90%) in a dose-dependent manner. …”
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İDARİ KOLLUK-ADLİ KOLLUK AYRIMINDA NORVEÇ POLİSİ VE SİVİL DENETİMİ by Melikşah Çırakoğlu

“…Söz konusu kavram, ülkemiz hukuk sistemi açısından oldukça yeni olduğundan; henüz doktrin tarafından yeterince değerlendirilmemiştir. …”
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Simulation of Image-Guided Microwave Ablation Therapy Using a Digital Twin Computational Model by Frankangel Servin, Jarrod A. Collins, Jon S. Heiselman, Katherine C. Frederick-Dyer, Virginia B. Planz, Sunil K. Geevarghese, Daniel B. Brown, William R. Jarnagin, Michael I. Miga

“…In microwave ablation (MWA), tissue-specific factors including tissue perfusion, hepatic steatosis, and fibrosis affect therapeutic extent, but current thermal dosing guidelines do not account for these parameters. …”
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Intra-mesenteric steroids for steroid-refractory graft-versus-host disease in pediatric patients: A safe option by Ana M. Aristizábal, Lina P. Montaña, Jaiber Gutiérrez, Diego Medina, Alexis A. Franco, Eliana Manzi, Ángela Devia Zapata, Walter Mosquera

“…Our findings suggest that intra-mesenteric steroid administration for managing hepatic and gastrointestinal graftversus-host disease may be considered an early adjuvant treatment in patients with steroidrefractory graft-versus-host disease.…”
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Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн... by Е. V. Garanina

“…MAFLD-hyperammonaemic patients also had the significantly higher male ratio, type 2 diabetes and severer hepatic steatosis rates vs. hyperammonaemia-negative MAFLD individuals. …”
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