Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…Pathogenically, CCM stems from a combination of systemic and local hepatic factors that, through hemodynamic and neurohormonal changes, affect the balance of cardiac function and lead to its remodeling. …”
Get full text

Impact of Weight Reduction on Thyroid Function and Nonalcoholic Fatty Liver among Egyptian Adolescents with Obesity by Mona Karem Amin, Ahmed Ibrahim Ali, Hesham Elsayed

“…It is also possible that hepatic steatosis affects thyroid function rather than the other way around.…”
Get full text

Chemical Characterization and Differential Lipid-Modulating Effects of Selected Plant Extracts from Côa Valley (Portugal) in a Cell Model for Liver Steatosis by Ricardo Amorim, Mário Pedro Marques, Catarina Melim, Carla Varela, Vilma A. Sardão, José Teixeira, Maria Inês Dias, Lillian Barros, Paulo J. Oliveira, Célia Cabral

“…(hemorrhages, urethritis, hepatitis), <i>Rumex scutatus</i> L. subsp. <i>induratus</i> (Boiss. and Reut.) …”
Get full text

Integrated SegFlow, µSIA, and UPLC for Online Sialic Acid Quantitation of Glycoproteins Directly from Bioreactors by Letha Chemmalil, Tanmay Kulkarni, Mathura Raman, Priya Singh, Yueming Qian, Chris Chumsae, Kyle McHugh, Zhuangrong Huang, Eric Hodgman, Michael C. Borys, Julia Ding, Gloria Li, Anthony Leone

“…ABSTRACT This study emphasizes the critical importance of closely monitoring and controlling the sialic acid content in therapeutic glycoproteins, including EPO, interferon‐γ, Orencia, Enbrel, and others, as the level of sialylation directly impacts their pharmacokinetics (PK), immunogenicity, potency, and overall clinical performance due to its influence on protein clearance via hepatic asialoglycoprotein receptors (ASGPR). The ASGPR recognizes and binds to glycoproteins exposed to terminal galactose or N‐acetylgalactosamine residues, leading to receptor‐mediated endocytosis. …”
Get full text

Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome by Jan Soukop, Ludmila Kazdová, Martina Hüttl, Hana Malínská, Irena Marková, Olena Oliyarnyk, Denisa Miklánková, Soňa Gurská, Zuzana Rácová, Martin Poruba, Rostislav Večeřa

“…<b>Results:</b> Fenofibrate treatment (100 mg/kg BW/day for four weeks) significantly decreased serum levels of triglyceride, (−77%) and free fatty acids (−29%), the hepatic accumulation of triglycerides, and the expression of genes encoding transcription factors involved in lipid metabolism (Srebf2, Nr1h4. …”
Get full text

Efficacy and Safety of Immunosuppressive Therapy for PBC–AIH Overlap Syndrome Accompanied by Decompensated Cirrhosis: A Real-World Study by Xiaoli Fan, Yongjun Zhu, Ruoting Men, Maoyao Wen, Yi Shen, Changli Lu, Li Yang

“…To explore the efficacy and safety of immunosuppressive therapy for the treatment of primary biliary cirrhosis-autoimmune hepatitis (PBC-AIH) overlap syndrome accompanied by decompensated cirrhosis. …”
Get full text

Analisis Peningkatan Produktivitas Tanaman Pangan Melalui Penerapan Green Teknologi by Muhammad Irfan Arya, rosanna rosanna rosanna, Detia Tri Yunandar D

“…Hasil aktivitas menunjukkan bahwa: (1) standar green teknologi memberikan kontribusi signifikan terhadap produkstivitas. (2) Sikap petani merupakan faktor penting yang yang sangat mempengaruhi perkembangan produksi di Kabupaten Bone dengan penggunaan green teknologi. (3) Praktik terhadap penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Wajo. (4) Kebijakan  terhadap penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Pinrang. (5) Penggunaan teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Sidrap. (6) Tata kelola dalam penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Soppeng. (7) Penggunaan standar teknologi yang ramah lingkungan akan menghasilkan limbah padi saat panen dalam bentuk kompos, bibit, serta makanan ternak ruminansia, yaitu hewan pemamah biak, seperti lembu, biri-biri, dan domba. (8) Penggunaan standar teknologi yang ramah lingkungan akan menghasilkan limbah padi pasca panen dalam bentuk sekam kasar, dedak, dan menir.…”
Get full text

Implications of the Intestinal Microbiota in Diagnosing the Progression of Diabetes and the Presence of Cardiovascular Complications by Alina Mihaela Leustean, Manuela Ciocoiu, Anca Sava, Claudia Florida Costea, Mariana Floria, Claudia Cristina Tarniceriu, Daniela Maria Tanase

“…Microbes can be considered a complex endocrine system capable of ensuring the proper functioning of the body but are also responsible for the development of numerous pathologies (diabetes, coronary syndromes, peripheral arterial disease, neoplasia, Alzheimer’s disease, and hepatic steatosis). Changes in the intestinal microbiota may influence the host’s sensitivity to insulin, body weight, and lipid and carbohydrate metabolism. …”
Get full text

Entegre Raporlamanın Sürdürülebilirlik Muhasebesiyle Olan İlişkisine Bakış ve Türkiye’de Entegre Raporlama Çalışmalarının Değerlendirilmesi by Sulhi Eski

“…İşletmelerin finansal tablolar yardımıyla sundukları bilgiler zaman içerisinde sosyal, çevresel ve ekonomik faaliyetleri önemseyen kişi ve kuruluşlar tarafından yeterli bulunmamıştır. Bu süreçte kurumsal hesap verebilirlik açısından da finansal ve finansal olamayan bilgilerin birlikte sunulması ihtiyacı ortaya çıkmıştır. …”
Get full text

Gagal Ginjal Akut pada Impending Eklampsia disertai Sindrom HELLP by Erni Savitri, Desmiwarti Desmiwarti

“…Lalu dirawat di ruang HCU Kebidanan, sejak setelah operasi sampai post operasi hari ke-3 didapatkan urine output < 10 cc/KgBB/jam lalu pasien pindah rawat ke bagian P.Dalam dengan diagnosis P1A0H1 post SCTPP ai impending eklampsia selesai regimen MgSO4 dosis maintenance + Sindrom HELLP + oligohidramnion berat + letak sungsang + Nifas hari ke-4 + Anemia sedang dalam perbaikan + Hipoalbumin dalam perbaikan + Gangguan faal hepar + Gangguan koagulasi + Hiponatremia + Anuria e.c AKI Riffle F e.c prerenal e.c dehidrasi. …”
Get full text

Dietary Valine Requirement of Juvenile Olive Flounder (Paralichthys olivaceus) by Jaehyeong Shin, Deahyun Ko, Mirasha Hasanthi, Gunho Eom, Kyeong–Jun Lee

“…Relatively lower lipid droplet in hepatic cell was observed in 4 g/kg Val group. Our findings suggested that dietary Val requirements for juvenile olive flounder would be 17.7–18.9 g Val/kg (35.4–37.8 g/kg on the basis of crude protein), estimated by quadratic regression analysis based on the weight gain, protein efficiency ratio, and protein retention efficiency.…”
Get full text

Free Radical Scavenging, Anti-Infectious, and Toxicity Activities from Stenochlaena palustris (Burm.f.) Bedd. Extracts by Rudi Hendra, Rohimatul Khodijah, Muhammad Almurdani, Yuli Haryani, Ari Satia Nugraha, Neni Frimayanti, Hilwan Yuda Teruna, Rizky Abdulah

“…It has been used to treat wound healing, infection, and diabetes. This study looked into the free radical scavenging activity, antiplasmodial activity, toxicity, and antibacterial activity against pathogenic bacteria. …”
Get full text

Kamu Girişimciliği Teorisi Kapsamında KİT’lerin Dünü Bugünü ve Yarını by Dilek Akbaş Akdoğan

“…Bu bağlamda KİT’lerin performansını arttırmak için iyi yönetişim ve reformlara vurgu yapılmıştır. Şeffaflık, hesap verilebilirlik, etkin denetim, sağlam yönetsel ve hukuki zemin iyi yönetişim için gerekli temel ögelerdir. …”
Get full text

The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…Consequently, directing therapeutic efforts towards inhibiting pyroptosis could potentially serve as an innovative approach in managing inflammation related chronic hepatic disorders. Methods GSDMD‐NTki/wt mice and Alb‐creki/wt mice were generated using CRISPR/Cas9 technology. …”
Get full text

Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81 by Gérard Vergoten, Christian Bailly

“…They display anticancer and antiviral effects, reducing the entry of hepatitis C virus (HCV) into hepatocarcinoma cells. …”
Get full text

Effect of Admission Hyperglycemia on Short-Term Prognosis of Patients with Non-ST Elevation Acute Coronary Syndrome without Diabetes Mellitus by Wei Liu, Zhijuan Li, Shiying Xing, Yanwei Xu

“…The clinical data of 498 patients with NSTE-ACS admitted to the Department of Cardiology of the First Affiliated Hospital of Henan University of Science and Technology between March 2018 and November 2020 were analyzed. …”
Get full text

Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations by Yuan-yuan Qi, Ya-ling Zhai, Xin-ran Liu, Xiao-xue Zhang, Ya-fei Zhao, Xiang-hui Ning, Zhan-Zheng Zhao

“…And the replication study was conducted in 1003 SLE patients and 815 healthy controls from Henan, Middle East of China. Further, we analyzed the eQTL effect to identify possible functional significance. …”
Get full text

Accuracy of Intraoperative Transesophageal Echocardiographic Doppler Parameters in Assessing the Right Ventricular Diastolic Function After Repair of Tetralogy of Fallot in Pediatr... by Nagarjuna Panidapu, Saravana Babu, Baiju S. Dharan, Barsha Sen, Thomas Koshy

“…The ASE-described parameters (late diastolic forward flow in the main pulmonary artery, right atrial dilatation, inferior vena cava dilatation, and hepatic venous flow reversal) were acquired to diagnose the RVDD. …”
Get full text

Prevalence and association of non-alcoholic fatty liver disease and insulin resistance among non-diabetic obese, overweight, and metabolically obese normal-weight adult patients at... by Samik Pramanik, Jimmy Barua, Lokanathan V, Sharmistha Roy

“…All subjects underwent detailed history, complete physical examination, laboratory test, and grading of hepatic fat by ultrasonography. Results: The mean age (mean± standard deviation) of the patients was 36.91±11.01 years with a range of 18–67 years. 53 (38.7%) and 84 (61.3%) of the patients were male and female, respectively. …”
Get full text

Exploring the Effects of Imidacloprid on Liver Health and the Microbiome in Rats: A Comprehensive Study by Alaa T. Qumsani

“…Histopathological examination showed that liver morphology changed significantly with the dose, including in terms of cellular disorganization and signs of stress, with an alteration in the hepatic architecture. Morphological changes were related to disturbances in the activity of liver enzymes, reflecting deteriorating liver function with increased imidacloprid exposure. …”
Get full text