Okul Geliştirme Yaklaşımları ve uygulama Süreçlerinin Değerlendirilmesi by Mehmet Üstüner, Seyfettin Abdurrezzak

“…Sonuç olarak okul geliştirmede kabul gören ve süreçte etkili olduğu düşünülen yaklaşım ve uygulamaların sırasıyla şunlar olduğu görülmüştür: (1) okulda olumlu ve destekleyici okul kültürü ve ikliminin geliştirilmesi (2) okul müdürünün liderlik rollerinin tanımlanması, (3) öğretmenlerin mesleki bilgi ve becerilerinin geliştirilmesi, (4) öğretim uygulamaları ve öğrenci öğrenme sonuçlarının geliştirilmesi, (5) öğretmenler arası işbirliği ve yardımlaşmanın teşvik edilmesi, (6) okul öz değerlendirmesi ve veriye dayalı karar verme uygulamalarına yer verilmesi, (7) okul hesap verebilirliğinin sağlanması, (8) okula uzman desteğinin verilmesi, (9) müfredatın değişimi (10) planlı okul gelişimi yaklaşımının benimsenmesi, (11) aile ve toplum desteğinin alınması ve (12) uygulamalarda sürdürülebilirliğin sağlanmasıdır.…”
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Pharmacophore modeling and QSAR analysis of anti-HBV flavonols. by Basireh Baei, Parnia Askari, Fatemeh Sana Askari, Seyed Jalal Kiani, Alireza Mohebbi

“…Due to its global burden, Targeting Hepatitis B virus (HBV) infection in humans is crucial. …”
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Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis by Tao Jiang, Jinhong Xu, Yang Lu, Xiaojin Chen, Yongxia Li

“…This study provides multiple lines of evidence that asiatic acid may alleviate alcoholic hepatitis in mice by modulating the NF-κB pathway.…”
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Local control and recurrence patterns after stereotactic irradiation delivered in more than 4 fractions for hepatocellular carcinomas and liver metastases: a retrospective study by Alizée Renan, Marie Bruand, Maria Jolnerovski, Aboubacar Diallo, Nicolas Demogeot

“…This study evaluated LC and recurrence patterns in patients administered hepatic SBRT in more than 4 fractions due to dosimetric constraints. …”
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Investigation of Multiple Hole Grouting for Reducing Water Inrush Risk in Underground Engineering by Changde Yang, Ling Li, Ying Li, Yakuan Gao

“…The method was applied in a case study in a coalmine in Henan province, China, in which the risk of the water inrush from karst aquifers has been reduced by grouting. …”
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Research on the movement process of erosion-denudation type debris flow in middle-low mountains based on particle algorithm model by Xiaofeng He, Yongfeng Gong, Jinkai Yan, Shichang Gao, Zheng He, Gang Zhang, Guorui Wang, Zhiyong Hu, Hui Wang

“…Debris flow is a significant geological hazard in the mountainous regions of China, characterized by its sudden onset, high mobility, and considerable destructive potential. In the Helan Mountains, debris flows primarily consist of coarse-grained materials transported by water flows, exhibiting both high destructive potential and a broad impact range. …”
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Reacciones fisiológicas y neuroquímicas del alcoholismo by Rodrigo Arias Duque

“…A nivel hepático tiene lugar, en su mayoría, el metabolismo del alcohol, produciéndose un hígado graso alcohólico, aumentando el tamaño, terminando en necrosis e inflamación grave del hígado; esto se llama hepatitis alcohólica, y si se sigue consumiendo alcohol se desarrollará la cirrosis. …”
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Regresión Logística Geográficamente Ponderada para identificar los factores explicativos de la distribución de usos de suelo en escenarios futuros de crecimiento urbano by Ramón Molinero-Parejo, Francisco Aguilera-Benavente, Montserrat Gómez-Delgado

“…La construcción de narrativas y el posterior cartografiado de escenarios futuros se ha revelado como una estrategia de planificación que puede ayudar en la organización de los usos del suelo y el transporte. El Corredor del Henares (Madrid) se ha escogido como caso de estudio, representando la evolución espacial de cinco usos del suelo urbano en tres escenarios disruptivos para 2050. …”
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Unraveling multimodality of digital health records by comparing mortality trajectories of diagnoses of diseases from over 12 million patients. by Hyojung Paik

“…The presented mortality trajectories successfully recapitulated established patterns of mortality for each country, while also revealing different trajectories leading to death, influenced by the modality of data. For example, viral hepatitis, a known predisposing feature of liver cancer in Asia, was observed to initiate in younger Koreans. …”
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Final Analysis of Post‐Marketing Surveillance for Avelumab + Axitinib in Patients With Renal Cell Carcinoma in Japan by Norio Nonomura, Taito Ito, Masashi Sato, Makiko Morita, Mie Ogi, Masahiro Kajita, Mototsugu Oya

“…Overall, 173 patients (52.7%) had ADRs of safety specifications of any grade, most commonly thyroid dysfunction (n = 69 [21.0%]), infusion reaction (n = 65 [19.8%]), and hepatic disorders (n = 45 [13.7%]). Objective responses occurred in 118 patients (36.0%), including complete or partial responses in 13 (4.0%) and 105 (32.0%), respectively; the disease control rate was 75.6%. …”
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The Role of PPARs in Lung Fibrosis by Heather F. Lakatos, Thomas H. Thatcher, R. Matthew Kottmann, Tatiana M. Garcia, Richard P. Phipps, Patricia J. Sime

“…Evidence is accumulating that the peroxisome proliferator-activated receptors (PPARs) play important roles in regulating processes related to fibrogenesis, including cellular differentiation, inflammation, and wound healing. PPARα agonists, including the hypolidipemic fibrate drugs, inhibit the production of collagen by hepatic stellate cells and inhibit liver, kidney, and cardiac fibrosis in animal models. …”
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Camrelizumab-Related Lethal Arrhythmias and Myasthenic Crisis in a Patient with Metastatic Thymoma by Bo Zhang, Laxman Gyawali, Zengzhang Liu, Huaan Du, Yuehui Yin

“…After detailed evaluation, ICI-related myocarditis, myositis, and hepatitis were diagnosed, and therapies including intravenous methylprednisolone were administered. …”
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Development and Validation of a LC/MS/MS Method for the Determination of Duloxetine in Human Plasma and Its Application to Pharmacokinetic Study by D. Chandrapal Reddy, A. T. Bapuji, V. Surayanarayana Rao, V. Himabindu, D. Rama Raju, Syed Syedba, H. L. V. Ravikiran

“…Analyte and IS were extracted from human plasma by liquid-liquid extraction using MTBE-n Hexane (80:20).The eluted samples were chromatographed on X-terra RP8 (50 mmx4.6 mm, 5 μm particle size) column by using mixture of 30 mM ammonium formate (pH-5.0±0.05) and acetonitrile as an isocratic mobile phase at a flow rate of 0.40 mL/min and analyzed by mass spectrometer in the multiple reaction monitoring (MRM) using the respective m/z 298.08→154.0 for duloxetine and 310.02→148.07 for IS. …”
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Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats by Joseph A. Olagunju, Gabriel O. Ajayi, Babatunde A. Murtala, Adejuwan A. Adeneye

“…The resultant increased gluconeogenesis and hepatic glycogen storage could be a detoxification mechanism whereby excess lactate due to increased glycolysis is converted to a non-toxic and neutral glucose to maintain pH balance in order to preserve the animals against DPDS toxicity.…”
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Dietary Pyridoxine Requirements of Coho Salmon (Oncorhynchus kisutch) Post-Smolts by Hairui Yu, Xinyue Zhang, Ziyi Yuan, Leyong Yu, Youzhi Zhao, Lingyao Li

“…The gradient pyridoxine levels did not yield any statistically (P>0.05) significant impact on the whole-body composition including moisture, ash, crude lipid, and crude protein. The hepatic pyridoxine concentration, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) activities increased significantly with dietary pyridoxine levels increasing from 0.32 to 4.08 mg/kg (P<0.05) and plateaued after that (P>0.05). …”
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Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition by Alisha Khan, Jonathan Hingre, Amit S. Dhamoon

“…Our objective in presenting this case is to highlight manganese neurotoxicity as a rare complication of TPN in a patient without known hepatic dysfunction and to emphasize the importance of routinely monitoring patients for the possible adverse effects of chronic TPN. …”
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Climate-change impacts on distribution, habitats, sustainability and cultivation planning of two economically and ecologically important forest trees (China fir and Masson pine) in... by Yanghui Zhao, Liang Xu, Ying Zhang, Yafeng Wen, Donglin Zhang

“…The suitable habitats for the two forest trees will change significantly under four shared socioeconomic pathways (SSPs) in the future three periods (2050 s, 2070 s and 2090 s): (i) the transition zones between tropical and sub-tropical regions and between temperate and sub-tropical regions are the main expansion (Yunnan, Henan, Hubei and Anhui) and loss areas (Guangdong, Hainan, Hunan and Taiwan), respectively. …”
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Antioxidant, Antimicrobial, and Protein Kinase Inhibition Profiling of C. ambrosioides Seed Extracts along with RP-HPLC by Saira Bano, Muhammad Waleed Baig, Mohammad K. Okla, Syeda Saniya Zahra, Nosheen Akhtar, Wahidah H. Al-Qahtani, Hamada AbdElgawad, Ihsan-Ul Haq

“…Highest antibacterial activity against K. pneumonia (14±1.61 mm ZOI) and antifungal activity against F. solani (17±1.38 mm ZOI) were shown by n-hexane and chloroform extracts, respectively. Ethyl acetate extract exhibited highest brine shrimps cytotoxicity (LC50 of 125 μg/ml). …”
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A Randomized Multicenter Study Comparing a Tacrolimus-Based Protocol with and without Steroids in HCV-Positive Liver Allograft Recipients by Ulf Neumann, Didier Samuel, Pavel Trunečka, Jean Gugenheim, Giorgio Enrico Gerunda, Styrbjörn Friman

“…Allograft reinfection with hepatitis C virus (HCV) occurs universally in liver transplant recipients. …”
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Anatomical and three-dimensional study of the abdominal vascular system in female rabbit using dissections and ultrasound by Aya A. Sulaiman, Rabab A. Naser, Ramadan A. Ahmed

“…The results showed that the mean hepatic artery diameter for 1-1.5 kg was 0.25&plusmn;0.04 cm while for 1.5-2 kg it was 0.37&plusmn;0.07, and the mean renal artery diameter for 1-1.5 kg was 0.20&plusmn;0.03 cm while for 1.5-2 kg it was 0.25&plusmn;0.04. …”
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