Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China by Rui Zhao, Guilun He, Lin Xiang, Melinda Ji, Rongheng He, Xudong Wei

“…In this study, we report two cases of leishmaniasis from Henan Province, China, in which Leishmania parasites were identified using mNGS technology, massively expediting diagnosis and treatment.ResultsOur report demonstrates that the mNGS method is applicable to peripheral blood samples (PB), which are far more readily available in clinical settings, in addition to bone marrow aspirate samples (BM), which are traditionally used for diagnosis of visceral leishmaniasis.ConclusionOur report validates the efficacy of mNGS technology as a rapid and accurate method of diagnosis for leishmaniasis.…”
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Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis by Min Du, Shimo Zhang, Min Liu, Jue Liu

“…Among the 14 risk factors analyzed, the most prevalent was a history of CVD (odds ratio [OR]=3.47), followed by age (per 10-year increase) (OR=1.79), current smoking (OR=1.76), hypertension (OR=1.57), smoking (OR=1.53), diabetes (OR=1.50), previous smoking (OR=1.30), and hepatitis C virus (HCV) infection (OR=1.18). However, there was no statistical significance associated with HIV-specific factors (abacavir use, efavirenz use, and CD4 nadir, etc.). …”
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Evaluation of land ecological security and driving factors in the Lower Yellow River Flood Plain based on quality, structure and function by Ge Zhai, Peng Ren, Ruihai Zhang, Bei Wang, Maoxin Zhang, Tingting He, Jinliang Zhang

“…Significant enhancements post-2010 were observed in Shandong Province, unlike the modest gains in Henan. Spatial heterogeneity in LES was evident across floodplain segments, with Jitai Beach witnessing the most decline, Dongying Beach the most improvement, and Zhengkai Beach the largest internal disparities. …”
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A Multicriteria Decision Model Based on Analytic Hierarchy Process for Managing Safety in Coal Mines by Xin Wang, Lei Zhang

“…The approach is then applied to evaluate a case study on the safety management of the Fushan Coal Industry Co., Ltd. Coal Mine in Henan Province of China. The matrix that evaluates each factor is obtained through a membership function and scored by experts, and the weight of each attribute is obtained through an analytic hierarchy process. …”
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Vaccination with Enzymatically Cleaved GPI-Anchored Proteins from Schistosoma mansoni Induces Protection against Challenge Infection by Vicente P. Martins, Carina S. Pinheiro, Barbara C. P. Figueiredo, Natan R. G. Assis, Suellen B. Morais, Marcelo V. Caliari, Vasco Azevedo, William Castro-Borges, R. Alan Wilson, Sergio C. Oliveira

“…The protection engendered by this vaccination protocol was confirmed by 42% reduction in worm burden, 45% reduction in eggs per gram of hepatic tissue, 29% reduction in the number of granulomas per area, and 53% reduction in the granuloma fibrosis. …”
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Enhancement of state response capability and famine mitigation: a comparative analysis of two drought events in northern China during the Ming dynasty by F. Tian, F. Tian, Y. Su, Y. Su, X. Chen, X. Chen, L. Tao, L. Tao

“…The defensive capabilities in Henan, Shaanxi, Gansu, and Ningxia showed significant improvement.…”
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The Role of mTOR Inhibitors in Liver Transplantation: Reviewing the Evidence by Goran B. Klintmalm, Björn Nashan

“…Despite the success of liver transplantation, long-term complications remain, including de novo malignancies, metabolic syndrome, and the recurrence of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC). …”
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Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice by Meng Li, Min Xu, Jichang Li, Lili Chen, Dongwei Xu, Ying Tong, Jianjun Zhang, Hailong Wu, Xiaoni Kong, Qiang Xia

“…Mice were pretreated with Alda-1 and subjected to a 90 min hepatic 70% ischemia model, and liver tissues or serum samples were collected at indicated time points after reperfusion. …”
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Early Kasai portoenterostomy in a 9-day-old newborn with extrahepatic biliary atresia: a case report highlighting improved prognosis with prompt intervention by Mortada H.F. El-Shabrawi, Gamal Eltagy, Mohamed Qinawy, Mohammed Am Oshi, Amjad Algethami, Nawaf A Alhujayri, Shaker S Alharthi, Abdullah M Alelyani, Naglaa M Kamal

“…The procedure involved creating a Roux-en-Y hepatic portojejunostomy to restore bile flow, preventing progression to biliary cirrhosis. …”
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Hepatocytic Differentiation Potential of Human Fetal Liver Mesenchymal Stem Cells: In Vitro and In Vivo Evaluation by Hoda El-Kehdy, Guillaume Pourcher, Wenwei Zhang, Zahia Hamidouche, Sylvie Goulinet-Mainot, Etienne Sokal, Pierre Charbord, Mustapha Najimi, Anne Dubart-Kupperschmitt

“…Following transplantation, naive and differentiated FL-MSC were engrafted into the hepatic parenchyma of newborn immunodeficient mice and differentiated in situ. …”
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Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients by Aleksandar R. Zivkovic, Karsten Schmidt, Annette Sigl, Sebastian O. Decker, Thorsten Brenner, Stefan Hofer

“…Furthermore, BChE activity showed an inverse correlation with the severity of the disease. Although hepatic function has previously been found essential for BChE production, we show here that the reduced BChE activity associated with systemic inflammation occurs independently of and is thus not caused by any deficit in liver function in these patients. …”
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Morbidity and Mortality following Surgery for Hip Fractures in Elderly Patients by Hebattu-allah E. Zaki, Shereen M. Mousa, Salma M. S. El Said, Ahmed K. Mortagy

“…The study was conducted in Ain Shams University Hospital, Ain Shams Specialized Hospital, and El-helal Hospital. Results. The subjects were categorized as survivors and nonsurvivors according to the 6-month mortality, and the groups were compared statistically according to this classification. …”
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Risk Assessment of Biological Asset Mortgage Loans of China’s New Agricultural Business Entities by Shuzhen Zhu, Yutao Chen, Wenwen Wang

“…Based on 1249 production and operation data samples of new agricultural entities in Zhejiang, Henan, and Shandong provinces, this study constructs an XGBoost model for empirical analysis and compares it with logical regression, support vector machine, and random forest algorithms to obtain the optimal model and feature importance value. …”
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Integrating ethics and democratic principles in chemistry education: a case study by Stojanovska Marina

“…Key activities included student-led discussions, such as exploring personal responsibility and moral dilemmas in chemistry, exemplified by the Heinz dilemma, and engaging in discourse on the possibility of breaking a law for morally justifiable reasons to comprehend the delicate balance between legal duties and moral responsibilities. …”
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Porcine transient receptor potential channel 1 promotes adipogenesis and lipid deposition by Yu Fu, Xin Hao, Jingru Nie, Peng Shang, Xinxing Dong, Bo Zhang, Dawei Yan, Hao Zhang

“…In vivo, transgenic mice expressing porcine TRPC1 exhibited aggravated high-fat diet–induced obesity, hepatic steatosis, and insulin resistance. Moreover, TRPC1 may facilitate adipogenesis via activating phosphatidylinositol 3 kinase/AKT and β-catenin signaling pathways. …”
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Protective Effect of Adipose-Derived Mesenchymal Stem Cell Secretome against Hepatocyte Apoptosis Induced by Liver Ischemia-Reperfusion with Partial Hepatectomy Injury by Zhihui Jiao, Yajun Ma, Yue Wang, Tao Liu, Qianzhen Zhang, Xiaoning Liu, Chenxi Piao, Boyang Liu, Hongbin Wang

“…Hepatocyte apoptosis plays a significant role in the pathological process of hepatic IRI. Adipose-derived stem cells (ADSCs) are known to repair and regenerate damaged tissues by producing bioactive factors, including cytokines, exosomes, and extracellular matrix components, which collectively form the secretome of these cells. …”
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Gallstone Ileus following Endoscopic Stone Extraction by Yoshiya Yamauchi, Noritaka Wakui, Yasutsugu Asai, Nobuhiro Dan, Yuki Takeda, Nobuo Ueki, Takahumi Otsuka, Nobuyuki Oba, Shuta Nisinakagawa, Tatsuya Kojima

“…An 85-year-old woman was an outpatient treated at Tokyo Rosai Hospital for cirrhosis caused by hepatitis B. She had previously been diagnosed as having common bile duct stones, for which she underwent endoscopic retrograde cholangiopancreatography (ERCP). …”
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Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques by Shery Jacob, Fathima Sheik Kather, Sai H. S. Boddu, Mahesh Attimarad, Anroop B. Nair

“…Rapid advances in the field of NS could resolve issues related to permeability-limited absorption and hepatic first-pass metabolism, offering promise for medications based on proteins and peptides. …”
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Variations of Gastrocolic Trunk of Henle and Its Significance in Gastrocolic Surgery by Yuan Gao, Yun Lu

“…In the isolation of subpyloric area or hepatic flexure of the colon for gastrectomy or right hemicolectomy, lymph node dissection and ligation are often performed at the head of the pancreas and superior mesenteric vein, during which even a minor inadvertent error may lead to unwanted bleeding. …”
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Brazilian Gold Miners Working Irregularly in French Guiana: Health Status and Risk Determinants by Amanda Figueira da Silva, Vivian da Cruz Franco, Maylis Douine, Hermano Gomes Albuquerque, Louise Hureau, Alice Sanna, Pamela Mosquera Atehortua, Rafael dos Santos Pereira, Simone da Silva Santos, Paola Barbosa Marchesini, Gustavo Bretas, Margarete do Socorro Mendonça Gomes, Yann Lambert, Martha Cecília Suárez-Mutis

“…Other diseases mentioned were skin diseases, bat bites, hepatitis, and HIV infection. This vulnerable population is constantly subjected to heavy routines and exposed to different diseases and infections that can spread across borders. …”
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