Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes by Shuang Gao, Yuanyuan Zhang, Kaini Liang, Ran Bi, Yanan Du

“…Potential mechanisms of MSC-based intervention on multiple pathological processes of T2DM, such as β-cell exhaustion, hepatic dysfunction, insulin resistance, and systemic inflammation, are also delineated. …”
Get full text

Sesquiterpenoids from <i>Dysoxylum amooroides</i> Stem Bark: Isolation, Structure Determination, and Cytotoxicity Against MCF-7 Breast Cancer Cells by Latifah Gunawan, Hidayat Nurul Mustofa, Al Arofatus Naini, Desi Harneti, Ace Tatang Hidayat, Nurlelasari Nurlelasari, Rani Maharani, Tri Mayanti, Sofa Fajriah, Khalijah Awang, Mohamad Nurul Azmi, Unang Supratman

“…Three sesquiterpenoids, guaianediol (1), alismol (2), and spathulenol (3), were isolated from the n-hexane and ethyl acetate extracts of the stem bark of Dysoxylum amooroides. …”
Get full text

Latent Inflammation and Insulin Resistance in Adipose Tissue by I. S. Stafeev, A. V. Vorotnikov, E. I. Ratner, M. Y. Menshikov, Ye. V. Parfyonova

“…It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. …”
Get full text

Chemopreventive Potential of Synergy1 and Soybean in Reducing Azoxymethane-Induced Aberrant Crypt Foci in Fisher 344 Male Rats by V. P. Gourineni, M. Verghese, J. Boateng, L. Shackelford, K. N Bhat

“…Colonic ACF enumeration and hepatic enzyme activities were measured. Reductions (%) in total ACF among treatment groups fed combinations were higher (67–77) compared to groups fed singly (52–64). …”
Get full text

Phytochemical composition, phytotoxicity, and ADME modeling of Artemisia absinthium L.: implications for food safety and pharmaceutical applications by Asmae Hbika, Ayoub Farihi, Mohammed Benali, Fatima-Zahrae Ed-darraz, Abdelhamid Bouyanzer, Mohammed F. Hawwal, Ramzi A. Mothana, Elkhadir Gharibi

“…Palmitic acid is the predominant fatty acid in the hexanic extract (18.7%), while linoleic acid is the main fatty acid in the ethyl acetate extract (42.4%). …”
Get full text

Irinotecan Plus S-1 Followed by Hepatectomy for a Patient with Initially Unresectable Colorectal Liver Metastases, Who Showed Severe Drug Rash with Oxaliplatin Plus 5-FU and Leucov... by Hiroyuki Komori, Toru Beppu, Yasuo Sakamoto, Yuji Miyamoto, Hiromitsu Hayashi, Katsunori Imai, Hidetoshi Nitta, Masayuki Watanabe, Hideo Baba

“…For unresectable colorectal liver metastases (CRLM), hepatic resection with or without chemotherapy is the only curative treatment that sufficiently achieves long-term survival. …”
Get full text

Induction of cell cycle arrest via the p21, p27–cyclin E,A/Cdk2 pathway in SMMC-7721 hepatoma cells by clioquinol by Huang Zhiwei, Wang Lianqiu, Chen Lifeng, Zhang Yifei, Shi Ping

“…In this study, we preliminarily examined the effect of clioquinol in human SMMC-7721 hepatoma and QSG-7701 normal hepatic cells. Our results indicated that clioquinol did not significantly affect survival of QSG-7701 cells, whereas it reduced cell viability in a concentration- and time-dependent manner in SMMC-7721 cells. …”
Get full text

TÜRKİYE’DE MU‘TEZİLE HAKKINDA YAPILAN ÇALIŞMALARIN DEĞERLENDİRİLMESİ by Yunus Cengiz

“…Mu‘tezile ile ilgili olarak birçok konu ayrıntılı olarak elealınmış olmasına rağmen henüz bazı konular ya hiç çalışılmamış ya da yeterliolarak ele alınmamıştır. …”
Get full text

Tocilizumab-Induced Acute Liver Injury in Adult Onset Still’s Disease by Michael Drepper, Laura Rubbia-Brandt, Laurent Spahr

“…Conclusion. Acute severe hepatitis can be associated with tocilizumab as documented in this case. …”
Get full text

Seasonality of Freeze Tolerance in a Subarctic Population of the Wood Frog, Rana sylvatica by Jon P. Costanzo, M. Clara F. do Amaral, Andrew J. Rosendale, Richard E. Lee

“…Spring frogs had comparatively low levels of the urea in blood plasma, liver, heart, brain, and skeletal muscle, as well as a smaller hepatic reserve of glycogen, which is converted to glucose after freezing begins. …”
Get full text

Cystic Form of Duodenal Dystrophy (Clinical Case) by D. E. Okonskaya, Kh. H. Ayvazyan, Yu. A. Stepanova, A. V. Zhao, E. A. Sokolova

“…The features of the operation were pronounced infiltrative changes and pronounced vitreous tissue edema, which made it difficult to mobilize the hepatic flexure of the colon and duodenum.Conclusion. …”
Get full text

Effect of Methomyl on Growth, Antioxidant System of GIFT (Oreochromis niloticus), and Residue in the Presence of Water Spinach (Ipomoea aquatica Forsk) by Xiaojun Jing, Yao Zheng, James P. Mulbah, Jiazhang Chen, Gangchun Xu

“…Water spinach altered GIFT’s hepatic oxidation system to some extent and effectively absorbed MET in water and transferred it to itself, and the degradation time was lower than the dietary standard time which termed as 15–20 days. …”
Get full text

HCV and Lymphoproliferation by Anna Linda Zignego, Carlo Giannini, Laura Gragnani

“…Hepatitis C virus (HCV) infection is a serious public health problem because of its worldwide diffusion and sequelae. …”
Get full text

Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIV/AIDS-Associated High-Grade NHL by Marco Mejia, Ariel Perez, Harold Watson, Daniel Sanchez, Jorge Parellada, Mario Madruga, S. J. Carlan

“…His lab values showed elevated anion gap with lactic acidosis and computed tomography (CT) of the abdomen showed a large soft-tissue mass arising from the left hepatic lobe. Biopsy of the abdominal mass demonstrated a high-grade diffuse large B-cell lymphoma. …”
Get full text

Elastography in Hepatology by Ludovico Abenavoli, Christophe Corpechot, Raoul Poupon

“…Currently, there are only a few studies that have evaluated TE effectiveness in chronic liver diseases, mostly in patients infected with the hepatitis C virus. Further studies are needed in patients with chronic liver disease, to assess the effectiveness of the fibrosis treatment.…”
Get full text

Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

“…However, therapeutic impact is restrained due to shortage of pancreas organ donors and instant inflammation occurring in the hepatic environment of the graft. We summarize on what is known about regenerative therapy in type 1 diabetes focusing on pancreatic islet transplantation and new avenues of cell substitution. …”
Get full text

Skeletal Cryptococcosis: Case Report and Review of the Literature by Lori Wood, Lil Miedzinski

“…A case of isolated cryptococcal skull infection is presented in a patient with unexplained CD4 lymphopenia and chronic hepatitis B. All cases of this disease reported in the English literature from 1956 to the present are reviewed. …”
Get full text

Low-Dose Tolvaptan for the Treatment of Dilutional Hyponatremia in Cirrhosis: A Case Report and Literature Review by Guo Shen, Hainv Gao

“…We report a case of forties man with a 20-year history of chronic hepatitis B presenting with yellow urine and skin. …”
Get full text

FİNANSAL ARAÇLARIN TMS/TFRS VE BOBİ FRS ÇERÇEVESİNDE MUHASEBELEŞTİRME ESASLARININ KARŞILAŞTIRILMASI by Osman Tuğay, Kadriye Arısoy

“…Çalışmada Uluslararası Muhasebe veFinansal Raporlama Standartlarının (UMS/UFRS), ülkemizdeki uyarlaması olanTürkiye Muhasebe ve Finansal Rapor-lama Standartları (TMS/TFRS) seti içerisindeTMS 39 Finansal Araçlar: Muhasebeleştirme ve Ölçme Standardı, tamamlanan yenisürümü ile 1 Ocak 2018 ve sonrası hesap dönemleri için uygulanmak üzereyayımlanan TFRS 9 Finansal Araçlar Standardı ve bağımsız denetime tabi olupTMS/TFRS uygulamayan işletmeler için 1 Ocak 2018’de yürürlüğe giren Büyük veOrta Boy İşletmeler için Finansal Raporlama Standartlarının (BOBİ FRS) finansalaraçlar ile ilgili düzenlemeleri incelenmiştir. …”
Get full text

Türk Kamu Personel Rejiminde Reform İhtiyacı: Reformu Gerektiren Dış Etkenler Ekseninde Bir Değerlendirme- Requirement of Reform In Turkish Public Personnel Regime: An Evaluation I... by Yakup Altan

“…Yapılan analiz neticesinde, belirtilen dış etkenlerin Türk kamu personel rejimiyle ilgili olarak rüşvet ve yolsuzlukla mücadeleye ve bu kapsamda saydamlık ve hesap verebilirliğe, kamu görevlilerinin görevleriyle ilgili olarak işledikleri iddia edilen suçlardan dolayı yargılanmaları konusuna, sendikal haklara, liyakat ilkesine, adil ve şeffaf bir ücret sisteminin kurulması gereğine ve çağdaş insan kaynakları satandartları doğrultusunda kapsamlı bir kamu personeli reformu yapılması gerekliliğine yoğun şekilde vurgu yapıldığı görülmektedir.…”
Get full text