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10061
ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma
Published 2023-03-01“…Chimeric antigen receptor T (CAR-T) cell therapy has shown great success in treating B cell malignancies; however, there are many challenges that limit their therapeutic efficacy in solid tumours. Immunotherapy of head and neck squamous cell carcinoma (HNSCC), and, in particular, oral squamous cell carcinoma (OSCC), presents a unique set of challenges including lack of consistently expressed tumour associated antigens (TAAs) and the immunosuppressive tumour microenvironment (TME). …”
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10062
Identifying relevant EEG channels for subject-independent emotion recognition using attention network layers
Published 2025-02-01“…ResultsThe model achieved average accuracies of 79.3% (CI: 76.0-82.5%), 69.5% (95% CI: 64.2-74.8%) and 60.7% (95% CI: 52.3-69.2%) on these datasets, revealing that EEG channels located along the head circumference, including Fp1, Fp2, F7, F8, T7, T8, P7, P8, O1, and O2, are the most crucial for emotion prediction. …”
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10063
Smart Filter Performance Monitoring System
Published 2023-02-01“…Three case studies are presented: an air purifier, a teaching building HVAC (heating, ventilation, and air conditioning) system, and a large-scale air cleaning system. …”
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10064
Intraoperative Management of Large Resuscitation-Associated Venous Air Embolism (VAE) for Emergent Neurological Surgery
Published 2020-01-01“…We report a 22-year-old previously healthy female who experienced a motor vehicle accident with severe facial and head trauma, and mixed subdural and epidural hematomas with an 8 mm midline shift. …”
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10065
Evaluation of the Definitions of “High-Risk” Cutaneous Squamous Cell Carcinoma Using the American Joint Committee on Cancer Staging Criteria and National Comprehensive Cancer Netwo...
Published 2014-01-01“…A retrospective review of head and neck cSCCs seen by an academic dermatology department from July 2010 to November 2011 was performed. …”
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10066
Hubungan Faktor Persepsi Mahasiswa Dalam Pengelolaan Ruang Rawat Inap Terhadap Kepuasan Mahasiswa Dalam Praktek Klinik Keperawatan Di RSUD Pariaman
Published 2020-10-01“…The results of the bivariate analysis showed that there was a correlation between students' perceptions about clinical leadership. leadership (p-value 0.003), supervision of the head of the room (p-value 0.042), coordination between practice supervisors (p-value 0.032), and practical work environment (p-value 0.033) with student satisfaction in nursing clinical practice. …”
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10067
The Stability of Gob-Side Entry Retaining in a High-Gas-Risk Mine
Published 2019-01-01“…The rational width of the filling body beside the roadway was determined, and a concrete roadway-side support with a headed reinforcement-integrated strengthening technique was proposed, which have been applied in engineering practice. …”
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10068
Photodynamic Antimicrobial Chemotherapy for Root Canal System Asepsis: A Narrative Literature Review
Published 2015-01-01“…Two reviewers independently conducted literature searches using a combination of medical subject heading terms and key words to identify relevant studies comparing information found in 7 electronic databases from January 2000 to May 2015. …”
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10069
Unexpected Bone Metastases from Thyroid Cancer
Published 2015-01-01“…The patient is a 37-year-old woman with a diagnosis of DTC who had focal areas of increased uptake in the head on WBS with no correlative findings on CT and MRI. …”
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10070
Distribution, traditional utilization, processing, and health benefits associated with the consumption of morama bean [Tylosema escululetum (Burch.)]: a survey from selected distri...
Published 2025-02-01“…It was found that morama bean is distributed in Botswana's sandy desert regions and is consumed by people who are native or migrated into these areas. Roasting in heated sand (mean = 4.93) and boiling fresh beans with water or milk (mean = 4.49) were the most popular methods of cooking morama beans. …”
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10071
IMPROVING EFFICIENCY OF THE JET PUMP AT LOW COEFFICIENTS OF EJECTION
Published 2015-06-01“…Mathematical and physical simulation of the centralejector operation with the substitution bodies shows the increase in pressure-head and efficiency coefficients in such apparatuses as compared to ejectors of the conventional form. …”
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10072
Assessment of the applied potential of sludge-derived hydrochar in terms of process parameters and product properties
Published 2024-10-01“…When the moisture content of sludge was 80.3%, the energy recoverable by hydrochars could be sufficient for the material to be heated up to phase transition. Evaluations of sludge characteristics in different regions and treatment processes were conducted, allowing HTC process parameters to be optimized in correlation with future resource utilization approaches. …”
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10073
Single cell transcriptome profiling reveals pathogenesis of bullous pemphigoid
Published 2025-02-01“…In lesional skin, non-immune cells upregulate pathways related to metabolism, wound healing, immune activation, and cell migration. LAMP3+DCs from cDC2 show stronger pro-inflammatory signatures than those from cDC1, and VEGFA+ mast cells, crucial for BP progression, are predominantly in lesional skin. …”
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10074
Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling
Published 2019-01-01“…HRECs were cultured in high glucose- (30 mM D-glucose) and hypoxia (cobalt chloride-treated)-stimulated diabetic condition to evaluate the antiangiogenic effects of SCU by CCK-8 test, cell migration experiment (wound healing and transwell), and tube formation experiment. …”
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10075
Early osteogenic differentiation of human dental stem cells by gelatin/calcium phosphate- Punica granatum nanocomposite scaffold
Published 2025-01-01“…Abstract Background Tissue engineering for bone regeneration aims to heal severe bone injuries. This study aimed to prepare and assess the early osteogenic differentiation effects of a gelatin/calcium phosphate- Punica granatum nanocomposite scaffold on stem cells from human exfoliated deciduous (SHED) and human dental pulp stem cells (HDPSCs). …”
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10076
How spinal GABAergic circuits modulate cerebral processing of postsurgical pain
Published 2025-02-01“…Surgical procedures cause tissue damage and inflammation, leading to peripheral and central sensitization, resulting in pain at rest or mechanical and heat hyperalgesia. In a rat model for post-surgical pain, spinal GABAergic transmission via GABAA receptors reduces mechanical hypersensitivity but has no effect on pain at rest. …”
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10077
Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change
Published 2024-01-01“…., pathogen infection, nutrient deficiency, plant senescence, heat stress, drought, osmotic stress, and hypoxia induce autophagy in plants. …”
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10078
Carlos Castillo-Chavez: A century ahead
Published 2013-07-01“…Sixteen years ago, I travelled to Cornell University with my colleague at the National Security Agency (NSA) Barbara Deuink to meet Carlos and hear about his vision to expand the talent pool of mathematicians in our country. …”
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10079
Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion
Published 2021-01-01“…Results from this preliminary in vitro evaluation suggest that the BWP has the potential to instill balance to the wound microenvironment by reducing the MMP-9/TIMP-1 ratio secretion from macrophages and progress previously stalled chronic wounds towards healing by triggering the release of growth factors from fibroblasts.…”
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10080
Study of Bone Marrow Mesenchymal and Tendon-Derived Stem Cells Transplantation on the Regenerating Effect of Achilles Tendon Ruptures in Rats
Published 2015-01-01“…TDSCs showed higher agility in tendon healing with better appearance density and well-organized longitudinal fibrous structure, though BMSCs also showed positive effects. …”
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