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    The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis by Shayan Mardi, Maryam Rashidian, Fatemeh Bastan, Ghazale Molaverdi, Sayed-Hamidreza Mozhgani

    Published 2025-01-01
    “…Abstract Background Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that leads to lifelong infection and multiple diseases, including HAM/TSP and ATLL. …”
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  3. 363

    HTLV-1 Tax-mediated inhibition of FOXO3a activity is critical for the persistence of terminally differentiated CD4+ T cells. by David Olagnier, Alexandre Sze, Samar Bel Hadj, Cindy Chiang, Courtney Steel, Xiaoying Han, Jean-Pierre Routy, Rongtuan Lin, John Hiscott, Julien van Grevenynghe

    Published 2014-12-01
    “…The mechanisms involved in the persistence of activated CD4+ T lymphocytes following primary human T leukemia/lymphoma virus type 1 (HTLV-1) infection remain unclear. Here, we demonstrate that the HTLV-1 Tax oncoprotein modulates phosphorylation and transcriptional activity of the FOXO3a transcription factor, via upstream activation of the AKT pathway. …”
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    Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. by Sydney R Coffey, Robert M Bragg, Shawn Minnig, Seth A Ament, Jeffrey P Cantle, Anne Glickenhaus, Daniel Shelnut, José M Carrillo, Dominic D Shuttleworth, Julie-Anne Rodier, Kimihiro Noguchi, C Frank Bennett, Nathan D Price, Holly B Kordasiewicz, Jeffrey B Carroll

    Published 2017-01-01
    “…To study the relationship between peripheral huntingtin levels and striatal HD phenotypes, we utilized a knock-in model of the human HD mutation (the B6.HttQ111/+ mouse). We treated mice with ASOs from 2-10 months of age, a time period over which significant HD-relevant signs progressively develop in the brains of HttQ111/+ mice. …”
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    ANALYSIS OF MOBILE TELECOMMUNICATION PATH LOSS IN RURAL COMMUNITIES by ALEXANDER OKANDEJI, FRANK ONAIFO, MATHEW OLAJIDE, AYODEJI OKUBANJO, HEZEKIAH FASANYA

    Published 2021-01-01
    Subjects: “…Hata-Okumura, path loss, signal strength, network planning, quality of service…”
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    PENGEMBANGAN INSTRUMEN PENILAIAN HASIL BELAJAR FISIKA BERORIENTASI HOTS (Higher Order Thinking Skills) PADA MATERI ELASTISITAS DAN HUKUM HOOKE by Dona Desilva, Indra Sakti, Rosane Medriati

    Published 2020-04-01
    “…ABSTRAK   Tujuan dari penelitian ini yaitu: 1) menghasilkan desain instrumen penilaian hasil belajar fisika berorientasi HOTS, 2) mengembangkan instrumen penilaian hasil belajar fisika berorientasi HOTS (Higher Order Thinking Skills) yang valid dan 3) mendeskripsikan karakteristik instrumen penilaian hasil belajar fisika berorientasi HOTS yang valid, pada materi Elastisitas dan Hukum Hooke. …”
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