ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma by Wei Dang, Qin Li, Xiaoying Wang

“…In this study, we performed transcriptomic analysis of HB samples from the GEO database and identified three distinct molecular subtypes with varying prognostic outcomes. …”
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Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis by Ce Chen, Jialin Wang, Mengqin Cheng, Haifeng Xie, Wei Li, Chaofeng Zhang

“…Our study revealed HB's beneficial effects in alleviating PF symptoms and restoring the intestinal mucosal barrier. …”
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The Effect of Diabetes Management Shared Care Clinic on Glycated Hemoglobin A1c Compliance and Self-Management Abilities in Patients with Type 2 Diabetes Mellitus by Tian Jiang, Chao Liu, Ping Jiang, Wenjun Cheng, Xiaohong Sun, Jing Yuan, Qiaoling Wang, Yanlei Wang, Shihui Hong, Haiyan Shen, Dongchun Zhu, Yi Zhang, Fang Dai, Jing Hang, Jiguo Li, Honglin Hu, Qiu Zhang

“…Methods. This study was a prospective cohort study of patients with T2DM participating in the DMSCC. …”
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Hemoglobin A1c to Detect Prediabetes or Type 2 Diabetes Mellitus in a Rural Population of Wardha District in India by Shilpa Gaidhane, Ranjit Sah, Quazi Syed Zahiruddin, Nazli Khatib, Shital Telrandhe, Sonali Choudhari, Abhay Gaidhane

“…Nearly half of type 2 diabetes mellitus (T2DM) cases go undiagnosed. This study assesses glycated hemoglobin A1c (HbA1c) for diagnosing T2DM and prediabetes in at-risk individuals. …”
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Effectiveness of shared decision-making for glycaemic control among type 2 diabetes mellitus adult patients: A systematic review and meta-analysis. by Edosa Tesfaye Geta, Dufera Rikitu Terefa, Wase Benti Hailu, Wolkite Olani, Emiru Merdassa, Markos Dessalegn, Miesa Gelchu, Dereje Chala Diriba

“…The sensitivity analysis was performed using a leave-one-out meta-analysis to quantify the impact of each study on the overall effect size in mean difference HbA1c%. …”
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Lung Function Abnormalities in Sickle Cell Anaemia by Yvonne A. Dei-Adomakoh, Jane S. Afriyie-Mensah, Audrey Forson, Martin Adadey, Thomas A. Ndanu, Joseph K. Acquaye

“…This was an analytical cross-sectional study involving 76 clinically stable, hydroxyurea-naive adult Hb-SS participants and 76 nonsickle cell disease (non-SCD) controls. …”
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FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors by Levi Makala, Salvatore Di Maro, Tzu-Fang Lou, Sharanya Sivanand, Jung-Mo Ahn, Betty S. Pace

“…The focus of our study is to investigate the ability of FK228 analogues to induce HbF using a novel KU812 dual-luciferase reporter system. …”
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Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or β-Thalassemia Trait? by Ari Indra Susanti, Edhyana Sahiratmadja, Gatot Winarno, Adhi Kristianto Sugianli, Herman Susanto, Ramdan Panigoro

“…Our study aimed to assess Hb level measured by midwives in primary health care facility at rural area of Jatinangor, Indonesia, and to explore whether the anemia was due to iron deficiency (IDA) or β-thalassemia trait (β-TT). …”
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Serum Uric Acid, Alanine Aminotransferase, Hemoglobin and Red Blood Cell Count Levels in Pseudoexfoliation Syndrome by Hüseyin Simavlı, Yasin Yücel Bucak, Mehmet Tosun, Mesut Erdurmuş

“…Further studies are needed to clarify the precise role of Hb, RBC, ALT, and UA in the pathogenesis of PEX.…”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…The primary analysis was an unadjusted treatment group comparison of glycosylated hemoglobinA1c (HbA1c) change from baseline to end of study (EOS). …”
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Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids by Ekta Lachmandas, Corina N. A. M. van den Heuvel, Michelle S. M. A. Damen, Maartje C. P. Cleophas, Mihai G. Netea, Reinout van Crevel

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Key oncogenes and candidate drugs for hepatitis-B-driven hepatocellular carcinoma progression by Liqin Ruan, Ningbo Fang, Xinhua Zhao, Weili Chen, Zhaoping Wu, Xiaoyong Wu

“…Abstract Background This study aimed to uncover the key hepatitis-B (HB)-related liver cancer (LC) promoting genes, and clarity their interrelationships, enrichments, impacts on LC immune infiltration, and potential drugs targeting these genes. …”
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The role of activated partial thrombin time in mediating the impact of poorly glycemic control on diabetic peripheral neuropathy in patients with type 2 diabetes mellitus by Hui Zhang, Minghui Chen, Lijie Sun, Wenwen Zhu, Wenwen Zhu, Tong Niu, Huzaifa Fareeduddin Mohammmed Farooqui, Hongxiao Wang, Bing Song, Jumei Wang, Haoqiang Zhang

“…AimThis study aims to investigate the role of activated partial thrombin time (APTT) as a potential mediator in the relationship between suboptimal glycemic control and diabetic peripheral neuropathy (DPN) in individuals with type 2 diabetes mellitus (T2DM).MethodsA total of 183 T2DM patients were enrolled in this study. …”
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Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses by John E. Schneider, Anjani Parikh, Ivana Stojanovic

“…**Objectives:** This study examined the use of insulin management services to enable patients to optimize insulin dosing to achieve HbA1c targets and subsequently reduce health care costs. …”
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Assessment of Gap between Knowledge and Practices among Type 2 Diabetes Mellitus Patients at a Tertiary-Care Hospital in Bangladesh by Farzana Saleh, Ferdous Ara, Fadia Afnan

“…This prompted us to evaluate what happens when old diagnosed patients receive DE. The study therefore assessed the association between knowledge and practices in terms of Hemoglobin A1c (HbA1c), body mass index (BMI), and waist circumference (WC) among 500 diagnosed T2 DM using a cross-sectional design. …”
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Glycaemic Control Impact on Renal Endpoints in Diabetic Patients on Haemodialysis by Danielle Creme, Kieran McCafferty

“…Glycaemic control was assessed from HbA1c results that were then further adjusted for albumin (Alb) and haemoglobin (Hb). …”
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Contribution of vitamin B 6 deficiency to anemia in children on regular hemodialysis by Fatma Atia, Hafez Bazaraa, Yara Abdelatty, Sarah Lotfy, Eman Eryan

“…However, it is noteworthy that the average hemoglobin (Hb) level approached the intended target. The incidence of Vitamin B6 deficiency was not found to be statistically significant within our study population. …”
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Designing Novel Interfaces via Surface Functionalization of Short-Chain-Length Polyhydroxyalkanoates by S. Vigneswari, J. M. Chai, K. Shantini, K. Bhubalan, A. A. Amirul

“…This review addresses the surface modification on biomedical applications focusing on short-chain-length PHA such as poly(3-hydroxybutyrate) [P(3HB)], poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)].…”
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Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages by R. Clive Landis, Pandelis Philippidis, Jan Domin, Joseph J. Boyle, Dorian O. Haskard

“…It is notable that individuals homozygous for the Hp 2 allele (a poorer antioxidant) are at increased risk of cardiovascular disease compared to the Hp 1 allele. In this study, we examined whether scavenging of polymorphic Hp:Hb complexes differentially generated downstream anti-inflammatory signals in cultured human macrophages culminating in interleukin (IL)-10 secretion. …”
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Associations between TGF-β1 Levels and Markers of Hemolysis, Inflammation, and Tissue Remodeling in Pediatric Sickle Cell Patients by Rayra P. Santiago, Magda O. S. Carvalho, Camylla V. B. Figueiredo, Luciana M. Fiuza, Rodrigo M. Oliveira, Sètondji C. M. A. Yahouédéhou, Valma M. L. Nascimento, Isa M. Lyra, Théo Araujo-Santos, Nívea F. Luz, Milena M. Aleluia, Caroline C. Guarda, Valéria M. Borges, Marilda S. Goncalves

“…Transforming growth factor beta (TGF-β) is a cytokine with important involvement in biological processes related to the pathogenesis of sickle cell disease (SCD), including endothelial and vascular dysfunction, inflammation, and hematopoietic homeostasis. This study is aimed at investigating associations between levels of TGF-β1 and classical laboratory biomarkers and inflammatory mediators, as well as the tissue inhibitor of metalloproteases-1 (TIMP-1) and matrix metalloproteinase-9 (MMP-9), in pediatric patients (n=123) with SCD in steady state: 84 with sickle cell anemia (HbSS) and 39 with hemoglobin SC disease (HbSC). …”
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