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    American Heritage Workbook: an interdisplinary approach / by Fox, Frank W.

    Published 1988
    View in OPAC
    Book
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    VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans. by Sung Min Han, Hajer El Oussini, Jelena Scekic-Zahirovic, Jack Vibbert, Pauline Cottee, Jeevan K Prasain, Hugo J Bellen, Luc Dupuis, Michael A Miller

    Published 2013-01-01
    “…The muscle signaling pathway localizes mitochondria to myofilaments, alters their fission/fusion balance, and promotes energy production. Here, we show that neuronal loss of the C. elegans VAPB homolog triggers metabolic alterations that appear to compensate for muscle mitochondrial dysfunction. …”
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    Article
  11. 4891

    A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy by Robert Hodgson, Matthew Walton, Helen Fulbright, Laura Bojke, Ruth Walker, Alexis Llewellyn, Sofia Dias, Lesley Stewart, David Steel, John Lawrenson, Tunde Peto, Mark Simmonds

    Published 2025-01-01
    “…These studies suggest that anti-vascular endothelial growth factor medications may help preserve vision but are also more expensive than laser therapy. The authors of these studies expressed doubts about the cost-effectiveness of anti-vascular endothelial growth factor medications. …”
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    S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis by Panpan Lian, Li Li, Renwei Lu, Bin Zhang, Junaid Wazir, Chaode Gu, Bojie Ma, Wenyuan Pu, Wangsen Cao, Zhiqiang Huang, Zhonglan Su, Hongwei Wang

    Published 2025-01-01
    “…Although persistent activation of signal transducer and activator of transcription 3 (STAT3) is implicated in its pathogenesis, the mechanisms underlying the sustained STAT3 activation remain poorly understood. Here, we identify sphingosine-1-phosphate receptor 3 (S1PR3) as a critical regulator of STAT3 activation and psoriasis pathogenesis, orchestrating a self-amplifying circuit that sustains keratinocyte hyperproliferation and chronic inflammation. …”
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    ENGINEERING EDUCATION: FORMAT CHANGE by Pavel M. Vcherashny, Natalia V. Gafurova, Maksim V. Rumyantsev, Olga A. Osipenko

    Published 2016-12-01
    Subjects: “…contemporary engineer's core competences…”
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    Cervical cancer care at a tertiary oncology facility in Uganda: Comparing daily practice with national treatment targets on cervical cancer control. by Marlieke de Fouw, Melissa W M Boere, Carolyn Nakisige, Mariam Nabwire, Jane Namugga, Israel Luutu, Jackson Orem, Jan M M van Lith, Jogchum J Beltman

    Published 2025-01-01
    “…The majority (86%) of patients presented with advanced stage of disease. More than half of patients never initiated (31%) or interrupted (30%) treatment. …”
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