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5261
Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus
Published 2025-02-01“…In vivo reporter followed by coupled in vitro transcription/translation (IVT) assays confirmed the role of mraZ G4 as a target interacting NMM to impose extreme antibacterial activity against both the gram-positive and -negative bacteria. In-cell and in vivo validation of NMM using RAW264.7 cells and Galleria mellonella; respectively, demonstrated that NMM exhibited superior antibiotic activity compared to well-established antibiotics, with no observed cytotoxicity. …”
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5262
Construction of novel pJRD215-derived plasmids using chloramphenicol acetyltransferase (cat) gene as a selection marker for Acidithiobacillus caldus.
Published 2017-01-01“…<h4>Background</h4>Acidithiobacillus caldus, a Gram-negative, chemolithotrophic sulfur-oxidizing bacterium, is widely applied in bioleaching. …”
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5263
Noninvasive oxygenation and ventilation strategies for viral acute respiratory failure: a comprehensive systematic review and meta-analysis
Published 2025-02-01“…The search encompassed databases such as Medline, Cochrane CENTRAL, and Embase to identify relevant indexed literature. Additionally, gray literature was included by consulting regulatory agencies. …”
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5264
Multidrug Resistant Enteric Bacteria from Cancer Patients Admitted in Douala Laquintinie Hospital, Littoral Region of Cameroon
Published 2024-01-01“…The increase in the number of Gram-negative infections among cancer patients, as shown in the present study, highlights the need for broad-spectrum therapy and effective planning of control programs to reduce bacterial diseases among cancer patients.…”
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5265
Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment
Published 2025-01-01“…Finally, the transcriptomic results suggest that bacteria death may be related to membrane destruction, metabolic disorders, and transport damage. HE staining and Gram staining also showed that inflammation was significantly alleviated after laser treatment.Conclusion: These findings propose a great solution for bacterial infection and also enrich the theoretical framework supporting the application of BP-Sr in the field of antibiosis. …”
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5266
Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study
Published 2025-01-01“…Maternal fasting and 1-hr glucose and metabolomics measured during a 2-hr 75-gram oral glucose tolerance test during early third trimester pregnancy were evaluated as phenotypes. …”
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5267
Association between Helicobacter pylori Infection and Occurrence of Anemia among Pregnant Women Attending Antenatal Care in Kulito Health Center, Halaba Zone, South Ethiopia, 2018
Published 2020-01-01“…Anemia in pregnancy is defined as a hemoglobin (Hb) concentration of less than 11 grams (gm)/deciliter (dl) in venous blood. Globally, it affects 1.62 billion people. …”
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5268
Biochemical, ecological and molecular characterization of Xenorhabdus anantnagensis associated with Steinernema anantnagense from India: evaluating nematode efficacy against Helico...
Published 2025-01-01“…Phenotypic characterization aligned the bacterium closely with X. anantnagensis, highlighting typical traits such as rod-shaped, gram-negative cells and absence of bioluminescence. …”
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5269
Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
Published 2025-02-01“…Here we investigated the molecular assembly, regulation, and function of BMCs in Fusobacterium nucleatum—a Gram-negative oral pathobiont that is associated with adverse pregnancy outcomes. …”
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5270
COVID-19 encephalopathy with severe neurological symptoms: a clinical case presentation with literature review
Published 2023-10-01“…The MRI describes a spectrum of neurovisual abnormalities, the most common of which are foci of leukoencephalopathy, changes in diffusion restriction imaging in the white, rarely in the gray matter, signs of microhaemorrhage and leptomeningitis. …”
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5271
Prevalence and Determinants of Geohelminthiasis among School-Age Children in Jimma City, Ethiopia
Published 2023-01-01“…Most (86.6%) of the STH-positive SAC had a single infection and a light infection intensity (88.2%), with a mean intensity of 367.4 eggs per gram. Location of Kebele (AOR = 2.73; 95% CI: 1.21–6.16, p=0.016), lack of hand washing after defecation (AOR = 6.39; 95% CI: 3.16–12.95, p<0.001), untrimmed fingernails (AOR = 2.65; 95% CI: 1.56–4.51, p<0.001), and lack of previous deworming (AOR = 2.90; 95% CI: 1.47–5.74, p=0.002) were significant predictors for STH infections among SAC. …”
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5272
¬¬Effect of Soil and Moisture Conservation Technologies on Growth and Grain Yields of Climbing Beans in Lake Mulehe Sub-catchment South-Western Uganda.
Published 2024“…Furthermore, mulching showed the highest effectiveness in promoting climbing bean growth and yield, with an average leaf number of 25, plant height of 2.4m, pod number of 84, and grain weight of 61 grams per 100 beans, surpassing both grass bunds and control plots. …”
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5273
Mangrove plants using deoxyribonucleic acid barcodes for enhancing biodiversity and conservation
Published 2024-07-01“…The Tamura 3-parameter + Gamma method in molecular evolutionary genetics analysis X software was used to measure and describe the genetic distances between different species and within the same species. …”
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5274
Therapeutic effectiveness of three commercial anthelmintics against strongylids in buffalo calves (Bubalus bubalis)
Published 2023-11-01“…Twenty-eight buffalo calves, naturally infected, with a parasite load ≥ 350 eggs per gram of faeces (EPG), and age between 2 and 3 months, with an average weight of 65.9 kgs, were selected. …”
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5275
Green synthesis of titanium dioxide photocatalyst using Lactobacillus bulgaricus for processing palm oil mill effluent
Published 2024-01-01“…Phenol, which is toxic and difficult to degrade biologically, could eliminated significantly (up to 81.12 percent) using a photocatalyst dose of 1 gram per liter at a time irradiation of 2.5 hour.CONCLUSION: The biological synthesis of nano titanium dioxide photocatalysts is affected by temperatures and metal oxide concentrations. …”
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5276
Seleksi Fitur Menggunakan Hybrid Binary Grey Wolf Optimizer untuk Klasifikasi Hadist Teks Arab
Published 2023-10-01“…This study proposes a feature selection method using the Hybrid Binary Gray Wolf Optimizer for Arabic text hadith classification. …”
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5277
Effectiveness of Gastric Cancer Endoscopic Screening in Intermediate-Risk Countries: Protocol for a Systematic Review and Meta-Analysis
Published 2025-02-01“…The search will be conducted in MEDLINE, SCOPUS, Embase, and Web of Science. Other gray literature sources will be additionally searched. …”
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5278
Differential vasoproliferative traits of Bartonella henselae strains associated with autotransporter BafA variants
Published 2025-01-01“…ABSTRACT Bartonella henselae, a Gram-negative facultative intracellular bacterium, is the etiological agent of cat-scratch disease and also causes bacillary angiomatosis in immunocompromised individuals. …”
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5279
Response surface methodology and adaptive neuro-fuzzy inference system for adsorption of reactive orange 16 by hydrochar
Published 2023-07-01“…Statistical error analysis verified the model’s accuracy and precision against experimental data.CONCLUSION: Response surface methodology and adaptive neuro-fuzzy inference system optimized process conditions. At pH 2, 2 gram per litre hydrochar dosage, 35 degree celcius , and a reactive orange 16 starting concentration of 250 milligram per liter, removal effectiveness reached 86.1 percent. …”
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5280
Bacterial Isolates and Their Antimicrobial Susceptibility Patterns Among Pediatric Patients with Urinary Tract Infections: A Retrospective Cross-Sectional Study at Tertiary Level i...
Published 2025-01-01“…In this study, 62% of gram-negative organisms were ESBL positive, among which the Proteus species demonstrated the highest ESBL positivity, followed by the Klebsiella species and E. coli. …”
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