USP22 inhibits microglial M1 polarization by regulating the PU.1/NLRP3 inflammasome pathway by Ming-chen Yu, Xiao-lin Li, Ming-liang Ning, Zhen-zhong Yan, Wan-tao Yu

“…Subsequently, BV-2 cells were treated with lipopolysaccharide (LPS) and interferon-gamma (IFN-γ) and interleukin (IL)-4 to induce M1 and M2 polarization, respectively. …”
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A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-brain rad... by Huaqu Zeng, MinZhi Zhong, Zongyou Chen, Shukui Tang, Zunbei Wen

“…Under the conditions of 3%/2 mm, and 2%/2 mm, the gamma passing rate of the IMRT QA was improved compared to VMAT, with an average increase of 0.6%, p=0.013, and 1.7%, p<0.001, respectively.ConclusionBoth non-coplanar VMAT and non-coplanar fixed field IMRT based on the Monaco TPS produce clinically acceptable results for HA-WBRT+SIB in patients with brain metastases. …”
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Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma by Angela J. Yoon, Richard D. Carvajal, Evan M. Graboyes, John M. Kaczmar, William G. Albergotti, Alexandra E. Kejner, Scott H. Troob, Elizabeth Philipone, Jean-Sebastien Anoma, Kent E. Armeson, Elizabeth G. Hill, Mary S. Richardson, Tina R. Woods, Bhishamjit S. Chera, Farzad Nourollah-Zadeh, Byung J. Lee, Subramanya Pandruvada, Antonis Kourtidis, Christina Kingsley, Elizabeth C. O’Quinn, Stephanie Mills, Victoria C. Jordan, Mike Spencer, Danielle Fails, Trevor D. McKee, Mark Zaidi, Alan Brisendine, Shane Horn, Shikhar Mehrotra, Besim Ogretmen, Jason G. Newman

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Prevalensi dan Pola Sensitivitas Antibiotik Klebsiella pneumoniae dan Escherichia coli Penghasil Extended Spectrum Beta Laktamase di RSUP Dr. M Djamil Padang by Suci Alillah Muztika, Ellyza Nasrul, Eugeny Alia

“…Metode: Penelitian ini merupakan studi deskriptif dengan rancangan potong lintang terhadap 828 sampel mikrobiologi dengan hasil kultur positif terhadap bakteri Gram negatif pada bulan Juni 2018- Mei 2019 yang memenuhi kriteria inklusi. …”
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Cardiac Tamponade Caused by Cutibacterium acnes: An Updated and Comprehensive Review of the Literature by Ghina Fakhri, Christelle Tayeh, Ghassan Dbaibo, Omar El Sedawy, Nour Abdul Halim, Fadi Bitar, Mariam Arabi

“…Cutibacterium species are Gram-positive microaerophilic rods that constitute part of the normal flora of skin and mucosal membranes. …”
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The additive effect of the stress hyperglycemia ratio on type 2 diabetes: a population-based cohort study by Cancan Cui, Jiayin Song, Lingyu Zhang, Ning Han, Wanqi Xu, Chen Sheng, Guangda Xin, Xiaofeng Cui, Lili Yu, Lin Liu

“…Participants were divided into SHR quartiles, and Cox proportional hazards regression and fine-gray competing risk models were used to assess SHR’s association with T2D onset, adjusting for fasting glucose and HbA1c. …”
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Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume-to-Platelet Count Ratio as Biomarkers in Critically Ill and Inj... by Dragan Djordjevic, Goran Rondovic, Maja Surbatovic, Ivan Stanojevic, Ivo Udovicic, Tamara Andjelic, Snjezana Zeba, Snezana Milosavljevic, Nikola Stankovic, Dzihan Abazovic, Jasna Jevdjic, Danilo Vojvodic

“…In general, the lowest levels had been found in patients with Gram-positive blood cultures. Conclusions. NLR and MPV were very good independent predictors of lethal outcome. …”
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Classification of benign and malignant solid breast lesions on the ultrasound images based on the textural features: the importance of the perifocal lesion area by А.А. Kolchev, D.V. Pasynkov, I.A. Egoshin, I.V. Kliouchkin, О.О. Pasynkova

“…Features were extracted from the source image, the image of the gradient module after applying the Sobel filter, and the image after the Laplace filter. Subsequently, eight gray-level co-occurrence matrices (GLCM) were constructed for each lesion, and 13 Haralick textural features were calculated for each GLCM. …”
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Dynamic analysis of the epidemiology and pathogen distribution of bronchoalveolar lavage fluid in children with severe pulmonary infection: a retrospective study by Muchun Yu, Mingchao Li, Huiqing Sun

“…Conclusions Severe pulmonary infections in children are significantly associated with age and types of infectious pathogens. Gram-negative bacteria are the primary cause of severe pulmonary infections in children. …”
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Aortic allografts in treatment of aortic valve and ascending aorta prosthetic endocarditis by S.V. Spiridonov

“…In majority of cases prosthetic endocarditis was caused by gram-positive cocci (Staphylococcus). In 84.6 % of cases it was associated with destruction of paravalvular structures and abscesses formation. …”
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Application of an Internet of Things Oriented Network Education Platform in English Language Teaching by Huizhen Li

“…By analyzing the current situation of the Internet of Things education platform, including its development and structure, this paper constructs the evaluation model of the combination of long-term memory neural network model and gray model and realizes the evaluation of the teaching effect of the Internet of Things education platform. …”
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Efficient biosorption of cadmium by Eucalyptus globulus fruit biomass using process parameters optimization by M. Samimi

“…The results from the experimental data of the adsorption studies were consistent with pseudo-second-order kinetics (maximum capacity of 128.2 milligram per gram), indicating that the chemical adsorption of cadmium on the used biomass occurring in monolayers.…”
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IMPLICATIONS OF BUTYLATED HYDROXYTOLUENE AND OPTIMIZED Piper nigrum EXTRACTS APPLICATION ON QUALITY OF STORED PORK by Adeola Adegoke, Kehinde Sanwo, Silas Hunge, Samuel Olakayode, Oluwafunmilayo Oyelude

“…BPAE had the lowest milligram malondialdehyde per gram tissue on d 10 of storage. Extract from BP may potentially contain compounds that could offer enhanced meat preservation and promote consumer health.…”
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The IclR-family transcriptional regulator XyrR controls flotation, motility, antibiotic production and virulence in Serratia sp. ATCC 39006 by Carlo Miguel Castro Sandoval, Carlo Miguel Castro Sandoval, George P. C. Salmond

“…ATCC 39006 (S39006) is a rod-shaped, motile, Gram-negative bacterium that produces a 𝛽-lactam antibiotic (a carbapenem) and a bioactive red-pigmented tripyrrole antibiotic, prodigiosin. …”
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A High-Status Middle Sarmatian Burial from the Kovalevka Burial Complex in the Volgograd Region by Valeriy M. Klepikov

“…On both sides of the cauldron there were two gray-clay pottery jugs made in Kuban pottery centers. …”
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Development of a Magnetic LED-based Sterilisator for Inactivation of Contaminant Bacteria by Yonatan ., Suryani Dyah Astuti, Khusnul Ain, Deny Arifianto, Ahmad Khalil Yaqubi, Perwira Annissa Dyah Permatasari

“…This study aims to evaluate combining a static magnetic field with photodynamic inactivation to the inactivation of S. aureus (a Gram-positive bacterium). The research utilized high-power blue LEDs and static magnetic fields generated by neodymium magnets. …”
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Oxytocin ameliorates lipopolysaccharide-induced acute orchitis model: interplay of oxidative stress and inflammatory pathways by Mohamed El-Sherbiny, Hany A. Elkattawy, Shimaa Hadhoud, Ahmed N. Nasr, Ateya M. Ibrahim, Ateya M. Ibrahim, Omar Z. Ameer, Noorhan Alsaleebi, Joud Asfari, Madaniah O. Zakari, Moaz A. Mojaddidi, Ehab K. Ali, Hailah M. Almohaimeed, Ahmed Abdeen, Sahar K. Ali, Mamdouh Eldesoqui, Mamdouh Eldesoqui

“…IntroductionLipopolysaccharide (LPS), a constituent of the outer membrane of Gram-negative bacteria, is a powerful inducer of systemic inflammation and has been extensively utilized in experimental models to simulate inflammatory responses and septic disorders. …”
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Invasive Aspergillus niger Is the Sole Etiological Agent for CSOM : A Clinical Case from Nepal by Ajay Kumar Chaurasiya, Rabindra Bhakta Pradhananga, Niranjan Prasad Sah, Basista Prasad Rijal, Bharat Mani Pokhrel, Santosh Dulal

“…Findings of laboratory analysis indicated that Gram staining of aural discharge displayed pus cells with fungal spores but did not exhibit bacteria. …”
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Plasma Sterilization Effectively Reduces Bacterial Contamination in Dental Unit Waterlines by Sarocha Noopan, Phattranit Unchui, Supitcha Techotinnakorn, Ruchanee Salingcarnboriboon Ampornaramveth

“…Moreover, treatment with plasma sterilization did not induce a change in the composition of microorganisms, as analyzed by Gram staining. Conclusion. Plasma sterilization, which is part of electrochemically activated water, effectively reduces bacterial contamination and reduces biofilms in dental unit waterlines.…”
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Cell Wall Protein 2 as a Vaccine Candidate Protects Mice Against <i>Clostridioides difficile</i> Infection by Shaohui Wang, Joshua Heuler, Jessica Bullock, Junling Qin, Soumyadeep Chakraborty, Agbendeh Lubem Nathaniel, Shifeng Wang, Xingmin Sun

“…Background/Objectives: <i>Clostridioides difficile</i> is a Gram-positive, spore-forming enteric pathogen that causes intestinal disorders, including inflammation and diarrhea, primarily through toxin production. …”
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