Investigation of cardiotoxic effects of marbofloxacin by Devran Coşkun, Burak Dik, Yasemin Korkmaz, Rahmi Canbar, Ayşe Er, Enver Yazar

“…In addition, it is to determine the effects of marbofloxacin on the liver function [alkaline phosphatase (ALP), alanine aminotransferase (ALT), gamma glutamyltransferase (GGT), total protein], renal function [blood urea nitrogen (BUN, creatinine] and hemogram [white blood cell (WBC), red blood cell (RBC), platelet, hemoglobin, hematocrit] parameters.…”
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Biochemical characteristics, genetic variants and treatment outcomes of 55 Chinese cases with neonatal intrahepatic cholestasis caused by citrin deficiency by Juan Li, Jintao Duan, Shuli He, Ying Li, Meifen Wang, Chengjun Deng

“…All NICCD patients were followed up until death or at least 1 year of age.ResultsCompared to INC group, significant increase was found in levels of total bilirubin, indirect bilirubin, total bile acid, gamma-glutamyl transpeptidase, alkaline phosphatase, prothrombin time, thrombin time, international normalized ratio, alpha-fetoprotein (AFP), Vitamin D, and Vitamin E of NICCD group, while alanine aminotransferase, albumin, fibrinogen, glucose, and Vitamin A levels showed significant decrease in the NICCD group (P < 0.05). …”
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Association between serum levels of 12 different cytokines and short-term efficacy of chemoradiotherapy in esophageal squamous cell carcinoma by Yaping Zhang, Qiufeng Qi, Ming Zhu, Yun Peng, Yanqing Bao, Jun Liu, Yanzhi Bi, Min Xiao, Shaohua Chi, Yongping Liu

“…Elevated baseline levels of IL-8 and interferon-gamma (IFN-γ) were correlated with a poorer prognosis. …”
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Inhibitory Effect of Flavonoid Extract of Lotus Leaf on Alcohol-Induced Gastric Injury by Antioxidant Capacity in Mice by Yi Chen, Qin Li, Zhiping Kuang, Xin Zhao, Ruokun Yi, Xiaowei He, Guangjing Feng

“…Besides, FELL significantly reduced the levels of interleukin 6 (IL-6), interleukin 12 (IL-12), tumor necrosis factor alpha (TNF-α), and interferon gamma (IFN-γ). The quantitative polymerase chain reaction (qPCR) and Western blot results proved that FELL upregulated the mRNA and protein expressions of SOD1, SOD2, CAT, epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), neuronal nitric oxide synthase (nNOS), and endothelial nitric oxide synthase (eNOS) and downregulated the expression of inducible nitric oxide synthase (iNOS) in the gastric tissue of mice with gastric injury. …”
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Radioisotope and Metal Concentrations in Borehole Water Samples of Umuahia and Umudike, Nigeria by J.C. Nnaji, O.U. Igwe, K.M. Onyedim, P. Okafor

“…Metal concentrations were analyzed with Graphite furnace Atomic Absorption Spectrophotometer (AAS) while radioisotopes were determined with gamma ray spectrometry. Results showed that mean values for conductivity, total solids, total dissolved solids, hardness and nitrates were lower than recommended values by the World Health Organization (WHO) and Standards Organization of Nigeria (SON). …”
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PARÂMETROS BIOQUÍMICOS EM OBESOS COM DIFERENTES PADRÕES DE TOLERÂNCIA À GLICOSE SUBMETIDOS A UM PROGRAMA DE EXERCÍCIOS E DIETA by Volmar Geraldo da Silva Nunes, Renan Maximiliano Fernandes Sampedro, Clayton Luiz Dornelles Macedo, José Henrique Souza da Silva

“…Este trabalho investigou as alterações nos parâmetros bioquímicos proporcionadas por um pro­grama de exercícios físicos e dieta alimentar (PEFDA) em sujeitos obesos com diferentes padrões de tolerância à glicose. …”
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Efectos adversos de los programas de apoyo alimentario en los hogares rurales de Calakmul, Campeche by Brenda Olvera, Birgit Schmook, Claudia Radel, Dominga Austreberta Nazar Beutelspache

“…Objetivo: se analizaron los efectos no desea-dos de los apoyos gubernamentales del Pro-grama de Inclusión Social Prospera, Progra-ma de Apoyo Alimentario (PA L), Programa Estratégico para la Seguridad Alimentaria (PESA) y Cocinas Escolares, en la producción de alimentos y en el patrón de consumo. …”
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Evaluation of Neutralizing Capacity of Tixagevimab plus Cilgavimab (AZD7442) against Different SARS-CoV-2 Variants: A Case Report Study with Comparison to a Vaccinated Population by Constant Gillot, Jean-Louis Bayart, Vincent Maloteau, Jean-Michel Dogné, Jonathan Douxfils, Julien Favresse

“…Neutralizing antibody (NAb) titers against several variants were assessed against the wild-type, alpha, beta, gamma, delta, omicron BA.5, and XBB.1.5 variants. …”
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Oral Administration of Lactobacillus plantarum 299v Reduces Cortisol Levels in Human Saliva during Examination Induced Stress: A Randomized, Double-Blind Controlled Trial by Hannah Andersson, Cecilia Tullberg, Siv Ahrné, Kristina Hamberg, Irini Lazou Ahrén, Göran Molin, Mikael Sonesson, Åsa Håkansson

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Unmanned Aerial Geophysical Remote Sensing: A Systematic Review by Farzaneh Dadrass Javan, Farhad Samadzadegan, Ahmad Toosi, Mark van der Meijde

“…The objective of this study is to comprehensively review the state-of-the-art UAV-based geophysical methods, encompassing magnetometry, gravimetry, gamma-ray spectrometry/radiometry, electromagnetic (EM) surveys, ground penetrating radar (GPR), traditional UAV RS methods (i.e., photogrammetry and LiDARgrammetry), and integrated approaches. …”
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Investigation of intracellular signals generated by γ-interferon and IL-4 leading to the induction of class II antigen expression by S. Vassiliadis, N. Kyrpides, D. Stravopodis, M. Grigoriou, I. Athanassakis, J. Papamatheakis

“…This study shows that the immunologically important class II antigens in human cells are up-regulated predominately via the same pathway after gamma-interferon (γ-IFN) treatment, whereas murine cells are activated by other signalling routes. …”
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Physiology‐based pharmacokinetic model with relative transcriptomics to evaluate tissue distribution and receptor occupancy of anifrolumab by Pradeep Sharma, David W. Boulton, Lynn N. Bertagnolli, Weifeng Tang

“…Here, we built a population physiology‐based pharmacokinetic (PBPK) model of anifrolumab by utilizing the physiochemical properties of anifrolumab, binding kinetics to the Fc gamma neonatal receptor, and target‐mediated drug disposition properties. …”
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Protection of liver sinusoidal endothelial cells using different preservation solutions by Julia H E Houtzager, Anne-Marieke van Stalborch, Charlotte Hofstee, Thomas M van Gulik, Jaap D van Buul

“…Endothelial integrity was assessed by measurement of cellular morphology and expression of membrane proteins: PECAM-1, ICAM-1 and Fc-gamma receptor CD32b (FcΥRCD32b). Endothelial barrier function was measured by electric cell-substrate impedance sensing. …”
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Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension by Jéssica Moraes Cruvinel, Elizabeth S. Greene, Rachel W. Read, Kichoon Lee, Sami Dridi, Paula R. Chen

“…Furthermore, abundance of transcripts related to fatty acid transport and adipogenesis, fatty acid binding protein 4 (FABP4) and peroxisome proliferator-activated receptor gamma (PPARγ), were increased in differentiated preadipocytes cultured at 20% O2 compared to 5% or 1% O2. …”
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The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis by Zheng Liang, Dajin Pi, Jianwei Zhen, Haizhen Yan, Chuiyang Zheng, July Liang Chen, Wen Fan, Qingliang Song, Jinyue Pan, Dongdong Liu, Maoxing Pan, Qinhe Yang, Yupei Zhang

“…The liver protein levels of Adenosine monophosphate-activated protein kinase–mammalian target of rapamycin (AMPK–mTOR)-mediated autophagy and ferroptosis markers, such as p-AMPKα/AMPKα, p-mTOR/mTOR, Beclin-1, microtubule associated protein 1 light chain 3 gamma (LC3), p62 (sequestosome 1 [SQSTM1/p62]), Kelch-like ECH-associated protein 1 (KEAP1), nuclear factor erythroid 2-related factor 2 (Nrf-2), ferritin heavy chain 1 (FTH1), and glutathione peroxidase 4 (GPX4), were restored by CSP. …”
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Insulin Resistance Mediates the Association Between Vitamin D and Non-Alcoholic Fatty Liver Disease by Caiyan Zou, Xuekui Liu, Maosheng He, Yan Sun, Yiquan Sang, Gangshan Peng, Yamei Ma, Houfa Geng, Jun Liang

“…Bioinformatics analysis showed that seven differentially expressed genes (DEGs) (solute carrier family 2 member 2 [SLC2A2], protein phosphatase 1 regulatory subunit 3E [PPP1R3E], CAMP responsive element binding protein 3-like 3 [CREB3L3], Interleukin-6 [IL-6], peroxisome proliferator-activated receptor gamma coactivator 1-alpha [PPARGC1A], nuclear factor kappa B inhibitor alpha [NFKBIA], and phosphoenolpyruvate carboxykinase 2 [PCK2]) were enriched in the IR pathway in comparison groups (VD group vs. lipid group), suggesting that VD improved NAFLD via changed IR. …”
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Chemokines and Growth Factors Produced by Lymphocytes in the Incompetent Great Saphenous Vein by Ewa Grudzińska, Sławomir Grzegorczyn, Zenon P. Czuba

“…Eotaxin, interleukin 8 (IL-8), macrophage inflammatory protein 1 A and 1B (MIP-1A and MIP-1B), interferon gamma-induced protein (IP-10), monocyte chemoattractant protein-1 (MCP-1), interleukin 5 (IL-5), fibroblast growth factor (FGF), granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), platelet-derived growth factor-BB (PDGF-BB), and vascular endothelial growth factor (VEGF) were assessed in culture supernatants by a Bio-Plex assay. …”
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Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease by Hongjun Ba, Yao Wang, Lili Zhang, Huishen Wang, Zhan-Peng Huang, Youzhen Qin

“…Gene sets related to complement and coagulation cascades, Toll-like receptor signaling pathway, Fc gamma R-mediated phagocytosis, NOD-like receptor signaling pathway, and regulation of actin cytoskeleton underwent differential activation in KD as opposed to the controls. …”
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Peroxisome Proliferator-Activated Receptor γ Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy by Kexing Hao, Jing Wang, Hengbin Yu, Lei Chen, Weibin Zeng, Zhengrong Wang, Guangdong Hu

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a key nuclear receptor transcription factor that is highly expressed in trophoblastic cells during embryonic attachment and is accompanied by rapid cell proliferation and increased lipid accumulation. …”
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Evaluación del contenido de materia orgánica y sus efectos, por registros geofísicos en el ejemplo de pozos petroleros del sector Varadero Oeste, Cuba by Olga Castro-Castiñeira, Ronal Barcala-Alvarez

“…Sin embargo, teniendo en cuenta el comportamiento de los registros geofísicos de pozos, donde son fundamentales la resistividad, porosidad y espectrometría gamma, se puede realizar una evaluación rápida de la capacidad de generación de hidrocarburos de secuencias descubiertas en pozos exploratorios. …”
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