Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database by Qian Qiao, Qian Qiao, Qian Qiao, Jiachen Sun, Jiachen Sun, Jiachen Sun, Ya Zheng, Ya Zheng, Yingying Mi, Yingying Mi, Yingying Mi, Yanan Gong, Yanan Gong, Jiahui Liu, Jiahui Liu, Jiahui Liu, Wenyue Rui, Wenyue Rui, Wenyue Rui, Yumei Ma, Yumei Ma, Yumei Ma, Yongning Zhou, Yongning Zhou, Min Liu, Min Liu

“…Regarding age, we noted an increasing incidence of adverse tumor events in middle-aged and elderly individuals compared to minors, except in the azathioprine group, where age was not identified as an independent risk factor. …”
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Integrating D-Dimer Thresholds into the Revised Caprini Risk Stratification to Predict Deep Vein Thrombosis Risk in Preoperative Knee Osteoarthritis Patients by Yi-Feng Guo MS, Dingding Zhang PhD, Yaping Chen MS, Weinan Liu BS, Na Gao MS, Xisheng Weng MD, Jin Lin MD, Jin Jin MD, Wenwei Qian MD, Xu Yang BS, Yin-Ping Zhang PhD, Xiaopeng Huo BS

“…Incorporating specific D-dimer thresholds into the four-level Caprini risk model enhances specificity and reduces unnecessary ultrasonography, outperforming both the use of individual indicators and the combination of the revised Caprini model with D-dimer level.…”
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Effect of Autolyzed Yeast on Performance and Physiological Indices of Broiler Chickens Reared at High Stock Density by Samaneh Ghaseminejad, Smayyeh Salari

“…Autolyzed yeast consists of ruptured or lysed cells and includes both intracellular and cell wall parts. Autolyzed yeast is usually concentrated or dried by liquid fermentation of Saccharomyces cerevisiae, and after autolysis or hydrolysis catalyzed by exogenous enzymes. …”
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Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy by Francesco Bruno, Francesco Bruno, Patrizia Spadafora, Ida Veltri, Mario L. Cuconati, Francesca Condino, Annamaria Cerantonio, Selene De Benedittis, Beatrice M. Greco, Beatrice M. Greco, Gemma Di Palma, Olivier Gallo, Luigi Citrigno, Antonio Qualtieri, Maurizio Cundari, Maurizio Cundari, Maurizio Cundari, Francesca Cavalcanti

“…Females scored higher besides APOE genotype.ConclusionsThese findings underscore the importance of considering both sex and APOE genotype when assessing cognitive performance in patients with temporal lobe epilepsy. …”
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Epilepsy care pathway: The Finnish model by Reetta Kälviäinen, Zakarya Hadj‐Allal, Jarkko Kirjavainen, Reina Roivainen, Tarja Linnankivi, Jukka Peltola, Kai Eriksson, Salla Lamusuo, Tuire Lähdesmäki, Johanna Annunen, Päivi Vieira, Virpi Tarkiainen, Leena Jutila, Anni Saarela, Leena Kämppi, Liisa Metsähonkala, Eija Gaily, Niina Lähde, Jaana Antinmaa, Sini Erme, Anna‐Leena Pirttisalo, Jari Virolainen, Milla Ylijoki, Laura Kela, Jonna Komulainen‐Ebrahim, Paula Sorjonen, Finnish Severe Epilepsy Coordination Group

“…A national multidisciplinary consensus panel, including specialists from both adult and pediatric neurology departments across all five Finnish university hospitals and from the patient organization, was established. …”
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Plasmodium falciparum transcription factor AP2-06B is mutated at high frequency in Southeast Asia but does not associate with drug resistance by Qiyang Shi, Changhong Wang, Wenluan Yang, Xiaoqin Ma, Jianxia Tang, Jiayao Zhang, Guoding Zhu, Yinlong Wang, Yaobao Liu, Xiaoqin He

“…To determine whether AP2-06B can alter the expression of pfk13 and pfcrt, as well as cause artemisinin and quinoline resistance in Plasmodium, we generated both a K3124R mutation and conditional knockdown of AP2-06B in Pf3D7 using CRISPR/Cas9-mediated genome editing.ResultsChIP-Seq analysis showed that AP2-06B can bind to the loci of the Plasmodium genes pfk13 and pfcrt. …”
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Gas drainage and utilization in coal mines in China: History, technological advances, and prospects by Guofu LI, Chao LI, Bichuan ZHANG, Yun XU, Zheng WANG, Xianjun ZHOU

“…This will help achieve both the utilization of gas with a full range of concentrations from coal mines and the goals of carbon neutrality and peak carbon dioxide emissions in the coal industry.…”
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Co-benefits of nature-based solutions: A health impact assessment of the Barcelona Green Corridor (Eixos Verds) plan by Tamara Iungman, Sergi Ventura Caballé, Ricard Segura-Barrero, Marta Cirach, Natalie Mueller, Carolyn Daher, Gara Villalba, Evelise Pereira Barboza, Mark Nieuwenhuijsen

“…Hourly temperatures from 25/06/2015 to 25/07/2015 were simulated, both with and without Green Corridors Plan implementation. …”
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THE RIGHT TO GOOD ADMINISTRATION AS A CONSTITUTIONAL RIGHT OF THE PERSON: EU EXPERIENCE by Tetyana Kaganovska, Vitalii Serohin

Subjects: “…human and citizen rights; constitutional status of a person; government, governance; administration; good governance; good administration, european union.…”
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Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges by Weigao Zhang, Hu Liu, Danyang Zhang, Yuguo Yi, Liang Tao, Yunfeng Zhu, Shuxian Huang, Xunan Zhao, Qianchao Shao, Peiqi Li, Yiwen Weng, Wei Lu, Jianfa Zhang, Haibing Zhang, Yuxin Chen, Dan Weng

“…Our results demonstrated that hepatocyte-specific deficiency of RIPK1 sensitized the liver to short-term fasting-induced liver injury and hepatocyte apoptosis in both male and female mice. Despite being a common physiological stressor that typically does not induce liver inflammation, short-term fasting triggered hepatic inflammation and compensatory proliferation in hepatocyte-specific RIPK1-deficient (Ripk1-hepKO) mice. …”
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Spatial-temporal analysis of carbon benefit and land use for low-carbon development strategies in Shandong Province, China by Hui Wen, Ziyu Zhong, Xujie Kong, Jichun Wang, Renqiang Li, Zhaosheng Wang, Shulin Yu, Zhen Xu, Hexin Chen, Qi Zhu, Pan Wang, Jiaquan Duan, Yan Ren

“…Assessing the carbon sequestration capacity of regional ecosystems is essential for achieving carbon neutrality goals. However, existing research often fails to comprehensively evaluate the spatial-temporal dynamic changes of ecosystem carbon emission and absorption. …”
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An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer by REN Jiaqiang, WU Shuai, SU Tong, LI Jie, HAN Liang, WU Zheng

“…Immunohistochemical analysis revealed that INPP4B expression was significantly higher in drug resistant pancreatic cancer tissues compared to non-drug resistant tissues, and lower in normal tissues than in both cancerous tissue types. Kaplan-Meier curves demonstrated that patients with low INPP4B expression had significantly better progression-free survival (PFS) than those with high expression (HR=2.874, 95% CI: 1.262-6.544, P=0.013). …”
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Mixture density networks for re-constructing historical ocean-color products over inland and coastal waters: demonstration and validation by Sundarabalan V. Balasubramanian, Ryan E. O’Shea, Ryan E. O’Shea, Arun M. Saranathan, Arun M. Saranathan, Christopher C. Begeman, Christopher C. Begeman, Daniela Gurlin, Caren Binding, Claudia Giardino, Michelle C. Tomlinson, Krista Alikas, Kersti Kangro, Moritz K. Lehmann, Moritz K. Lehmann, Lisa Reed

“…Our model is validated on satellite match-ups corresponding to the SeaWiFS Bio-optical Archive and Storage System (SeaBASS) database. For both training and validation, the hyperspectral in situ radiometric and absorption datasets were resampled via the relative spectral response functions of MODIS, MERIS, and VIIRS to simulate the response of each multispectral ocean color mission. …”
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Effect of Irrigation Interval and Corn (Zea mays L.)-Sorghum (Sorghum bicolor L.) Intercropping on the Quantitative and Qualitative Characteristics of Fodder by Saeed Sadeghzadeh Hemayati, Hamed Mansouri, Mohsen Shahsavarpour

“….) – sorghum (Sorghum bicolor L.) intercropping under normal irrigation and moisture stress conditions was reported as 1.35 and 1.62 respectively, which indicated the superiority of corn and sorghum intercropping over the monoculture of both plants, especially under stress conditions. …”
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Legitimising lithium mining: Global energy transition and green developmentalism in Jujuy, Argentina by Felix Malte Dorn, Kristina Dietz

“…In this article, we build on this strand of literature, assuming that decarbonisation – as the overarching goal of the energy transition – influences the decisions taken over lithium mining and the narratives used for its legitimisation. …”
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The greenhouse gas observation mission with Global Observing SATellite for Greenhouse gases and Water cycle (GOSAT-GW): objectives, conceptual framework and scientific contribution... by Hiroshi Tanimoto, Tsuneo Matsunaga, Yu Someya, Tamaki Fujinawa, Hirofumi Ohyama, Isamu Morino, Hisashi Yashiro, Takafumi Sugita, Satoshi Inomata, Astrid Müller, Tazu Saeki, Yukio Yoshida, Yosuke Niwa, Makoto Saito, Hibiki Noda, Yousuke Yamashita, Kohei Ikeda, Nobuko Saigusa, Toshinobu Machida, Matthias Max Frey, Hyunkwang Lim, Priyanka Srivastava, Yoshitaka Jin, Atsushi Shimizu, Tomoaki Nishizawa, Yugo Kanaya, Takashi Sekiya, Prabir Patra, Masayuki Takigawa, Jagat Bisht, Yasko Kasai, Tomohiro O. Sato

“…With a projected operational lifetime of seven years, GOSAT-GW will provide vital space-based constraints on both anthropogenic and natural GHG emissions. These measurements will contribute significantly to climate change mitigation efforts, particularly by supporting the Global Stocktake (GST) mechanism, a key element of the Paris Agreement.…”
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Modulating the sulfurization procedure to decrease by-product formation for one-step catalytic synthesis of sulfur-containing chemicals by ZhiZhi Xu, Jian Fang, Min Luo, Dedong He, Dingkai Chen, Jichang Lu, Yongming Luo

“…The one-step synthesis of sulfur-containing chemicals, methanethiol (CH3SH), from syngas and hydrogen sullfide (H2S) mixtures shows the enormous potential for extending the application of both C1 chemistry and sulfur resource recycling and utilization. …”
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Nursery of red tilapia Oreochromis niloticus in a small-scale aquaponics system with different stocking densities by Yani Hadiroseyani, Anita May Sharly, Dadang Shafruddin, Apriana Vinasyiam

“…The study was conducted using a completely randomized design at three levels of stocking density, namely 250 fish/m2, 375 fish/m2, and 500 fish/m2 of red tilapia at an initial size of 6.8 ± 0.35 cm, with 30 net pots of bok choy plant as co-culture. The results that the increase in fish population escalated the productivity of both fish and vegetable in 30 days farming period. …”
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Impact of glucocorticoids on patients’ quality of life: a qualitative study assessing face validity and feasibility of the Steroid PRO in patients with inflammatory gastroenterolog... by Shaney L Barratt, Emma Dures, Mwidimi Ndosi, Michelle Sharp, Sebastian E Sattui, Jill Dawson, Susan M Goodman, Sarah L Mackie, Tom Creed, Catherine L Hill, Joanna C Robson, Pamela Richards, Susan Bridgewater, Christine A Silverthorne, Jen Orme, Anne-Marie T Sweeney, Elizabeth Arthurs, Genevieve Osborne, Giles Dunhill, Richard P Ramonell, Timothy Patton

“…Additionally, the feasibility of using the Steroid PRO with both patients and HCPs has been established. Future work should include quantitative testing of the Steroid PRO as an outcome measure within clinical trials in these conditions.Trial registration number NCT06314451.…”
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The Sunburst Arc with JWST. III. An Abundance of Direct Chemical Abundances by Brian Welch, T. Emil Rivera-Thorsen, Jane R. Rigby, Taylor A. Hutchison, Grace M. Olivier, Danielle A. Berg, Keren Sharon, Håkon Dahle, M. Riley Owens, Matthew B. Bayliss, Gourav Khullar, John Chisholm, Matthew Hayes, Keunho J. Kim

“…We also detect the density-sensitive doublets of [O ii ] λλ 3727, 3730, [S ii ] λλ 6718, 6733, and [Ar iv ] λλ 4713, 4741, which constrain the density in both the low- and high-ionization gas. With these temperature and density measurements, we measure gas-phase abundances with similar rigor as studies of local galaxies and H ii regions. …”
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