Development and characterization of orthotopic patient-derived xenograft models of peritoneal metastatic mucinous appendiceal adenocarcinoma by I. Ito, V.K. Pattalachinti, A.M.G. Yousef, S. Chowdhury, M.M. Fanaeian, E. Haque, B.B. Gunes, M. Yousef, E.R. Salle, M.A. Zeineddine, S. Ji, R. Li, W. Wang, B.A. Helmink, M.W. Taggart, M.G. White, K.F. Fournier, N.W. Fowlkes, J.P. Shen

“…Comparison of histological, immunohistochemical, and molecular analyses including both RNA and DNA sequencing revealed that the PDX models recreate many of the features of metastatic AAs, but also displayed several differences between paired PDX and human tumors, highlighting the intratumoral heterogeneity of AAs within each patient. …”
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Phytochemical analysis, antioxidant, anti-inflammatory and enzyme inhibitory activities of bean pear (Pyrus calleryana fruit) by Huan Zhao, Huan Zhao, Qinqin Wang, Lanlan Yang, Lanlan Yang, Yuanquan Ran, Qiong Hu, Yi Hong, Minyi Tian, Minyi Tian, Minyi Tian

“…In the antioxidant activity, WE and EE showed marked free radical scavenging effects on both ABTS (2.33 ± 0.15 μg/mL and 2.23 ± 0.15 μg/mL, respectively) and DPPH (5.93 ± 0.55 μg/mL and 7.07 ± 0.23 μg/mL, respectively), especially, their scavenging effects on DPPH free radicals were superior or equivalent to that of BHT (7.47 ± 0.47 μg/mL). …”
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A Mixed Project-and-Stock Portfolio Optimization Model with Mean-SemiVariance-SemiEntropy Approach by Amirhosein Khayyatian, Majid Shakhsi-Niaei

“…However, this study extends the scope of portfolio optimization to encompass both project and stock investments. This is a critical advancement as investors increasingly grapple with allocating budgets across these two asset types simultaneously. …”
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The measurement of microplastics in surface water and their impact on histopathological structures in wading birds of district Lahore by Shaza Mehboob, Khalid Mahmood Anjum, Hamda Azmat, Muhammad Imran

“…The frequency and prevalence percentages followed the order: 0.5 mm > 0.5–1 mm > 1–2 mm > 2–3 mm > 3–4 mm > 4–5 mm > 0 mm (0 mm as control).This investigation contributes to the growing documentation of MPs abundance in freshwater ecosystems and provides a baseline for future studies on MPs pollution in the Ravi River.…”
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Endoscopic retrograde cholangiopancreatography combined with extracorporeal shock wave lithotripsy for the removal of large gallbladder stones: a pilot study by Liang Zhu, Jinli He, Zhenzhen Yang, Xi Huang, Junbo Hong, Xiaojiang Zhou, Youxiang Chen, Guohua Li

“…With respect to post-EGPC adverse events, one patient developed mild post-ERCP pancreatitis, and no other adverse events occurred. Both the technical success rate and clinical success rate of ERCP combined with ESWL were 83.3% and the incidence of adverse events was 16.7%. …”
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Correlation between discharge readiness and uncertainty in illness among parents with preterm infants hospitalized in NICU (NICU早产儿父母出院准备度与疾病不确定感的相关性分析)... by TAN Jilei (谭继磊), WEI Qin (韦琴), LIANG Jie (梁洁), LIANG Hua (梁华), TENG Xiaoyun (滕小芸), TANG Lihua (唐利华), SONG Jingwen (宋静雯), HE Ting (何婷)

“…Conclusion The discharge readiness and illness uncertainty of parents of premature infants are both at a moderate level, and they are closely related. …”
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Impact of ambient temperatures on Alzheimer's disease and other dementia mortality among elderly patients aged 60 years and older in China by Rui Zhang, Lu Sun, Ai-Nan Jia, Si-Yuan Wu, Yu Wang, Song-Wang Wang, Qing Guo, Yu-Jie Meng, Juan Liang, Wan Huang, Yong-Hong Li, Jing Wu

“…In addition, the attributable fractions (AFs) of mortality due to non-optimal ambient temperatures were calculated. The study found that both low and high non-optimal temperatures were associated with an increased risk of death from AD and other dementias, with an inverted J-shaped exposure–response curve. …”
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Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment by Tatsuya Usui, Masashi Sakurai, Shuhei Enjoji, Hideyoshi Kawasaki, Koji Umata, Takashi Ohama, Nobuyuki Fujiwara, Ryotaro Yabe, Shunya Tsuji, Hideyuki Yamawaki, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Koichi Sato

“…Here, we developed an ALI organoid model from normal and tumor colorectal tissues of human patients. Both organoids were successfully generated and showed cystic structures containing an epithelial layer and surrounding mesenchymal stromal cells. …”
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Effect of Physical Activity on Physical and Mental Health in Young Cancer Patients and Survivors: A Systematic Review of RCTs and CCTs by Ann Christin Schneider, Sofia Anzeneder, Lars Rehbein, Eva Katharina Brack, Mirko Schmidt, Valentin Benzing

“…Studies included inpatients (18), survivors (11), or both (2). Chronic PA interventions, such as aerobic, resistance, or combined motor-cognitive training, were implemented. …”
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Single-Nucleus RNA Sequencing Reveals Cellular Transcriptome Features at Different Growth Stages in Porcine Skeletal Muscle by Ziyu Chen, Xiaoqian Wu, Dongbin Zheng, Yuling Wang, Jie Chai, Tinghuan Zhang, Pingxian Wu, Minghong Wei, Ting Zhou, Keren Long, Mingzhou Li, Long Jin, Li Chen

“…The same cell types were present in the LDM at both growth stages, but their proportions and states differed. …”
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Mid-term outcomes of percutaneous pulmonary valve replacement with Edwards-Sapien bioprosthesis in native right ventricular outflow tract by Yassin Belahnech, Gerard Martí-Aguasca, Laura Dos-Subirà, Pedro Betrian-Blasco, Bruno García del Blanco, Maria Calvo-Barceló, Eduard Ródenas-Alesina, Antonia Pijuan-Domènech, Ferran Gran, Queralt Ferrer, Gemma Giralt-García, Berta Miranda, Blanca Gordon, Víctor González-Fernández, José A. Barrabés, Ferran Roses-Noguer, Ignacio Ferreira-González

“…Overall, PPVR with the ES valve demonstrates satisfactory mid-term outcomes in both native and non-native RVOTs.…”
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Development and validation of a machine learning model to predict the risk of lymph node metastasis in early-stage supraglottic laryngeal cancer by Hongyu Wang, Hongyu Wang, Hongyu Wang, Zhiqiang He, Zhiqiang He, Zhiqiang He, Jiayang Xu, Jiayang Xu, Ting Chen, Ting Chen, Ting Chen, Jingtian Huang, Jingtian Huang, Jingtian Huang, Lihong Chen, Lihong Chen, Lihong Chen, Xin Yue, Xin Yue, Xin Yue

“…All six ML models performed well, and in both internal and independent external validations, the eXtreme Gradient Boosting (XGB) model outperformed the other models, with AUC values of 0.87 and 0.80, respectively. …”
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Platelet-rich plasma combined with gypenosides for the treatment of psoriasis-like inflammation in mice by LI Dandan, WANG Bing, GE Yu, CHENG Hong, LI Mengxue, WANG Zhicheng, XIA Rong

“…Pathological examination showed that both the epidermal layer thickness (P<0.01) and epidermal cell proliferation (P<0.05) decreased in all treatment groups; IL-17A expression levels were 9.02±2.54, 16.56±3.49, 10.01±1.83, 11.12±2.48 and 10.50±2.16, and TNF-α expression levels were 223.36±70.34, 377.36±58.47, 265.42±45.14, 262.94±33.29 and 268.94±26.80 respectively. …”
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Shocked POststarburst Galaxy Survey. IV. Outflows in Shocked Poststarburst Galaxies Are Not Responsible for Quenching by Antoniu Fodor, Taylor Tomko, Mary Braun, Anne M. Medling, Thomas M. Johnson, Alexander Thompson, Victor D. Johnston, Matthew Newhouse, Yuanze Luo, K. Decker French, Justin A. Otter, Akshat Tripathi, Margaret E. Verrico, Katherine Alatalo, Kate Rowlands, Timothy Heckman

“…Shocked POstarburst Galaxies (SPOGs) exhibit both emission lines suggestive of shock-heated gas and poststarburst-like stellar absorption, resulting in a unique subset for galaxy evolution studies. …”
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Triceps insertion violation from commonly applied olecranon plating system: a comparison by Ahmed A. Habis, MD, MSc, FRCSC, Kevin Nguyen, MASc, Julie Chan, MD, MHSc, FRCSC, Emad Anam, MD, MSc, FRCSC, Ryan T. Bicknell, MD, MSc, FRCSC, Heidi-Lynn Ploeg, PhD, PEng, FASME, FORS, Parham Daneshvar, MD, FRCSC

“…Results were compared with both 2D and 3D measurements and the 2D surface area measurements of 2 previous studies. …”
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A Program for Master of Science in Environment and Natural Resources (MENR) by Kabale University

“…According to UN Sustainable Development Goals (SDG), the Goals and targets will stimulate action over the next 15 years in areas of critical importance for humanity and the planet. …”
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How to protect the proximal bronchial tree during stereotactic radiotherapy of ultracentral lung tumors: Lessons from MR-guided treatment by Sebastian Regnery, Efthimios Katsigiannopulos, Hin Lau, Philipp Hoegen-Saßmannshausen, Fabian Weykamp, Claudia Katharina Renkamp, Carolin Rippke, Fabian Schlüter, Sophia Albert, Jan Meis, Marietta Kirchner, Alexandra Balzer, Nicolaus Andratschke, Matthias Guckenberger, Jürgen Debus, Sebastian Klüter, Juliane Hörner-Rieber

“…Conclusions: Both intrafractional breathing motion and interfractional translations may impact doses to the PBT during SBRT of ULT. …”
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Innovación en sueño by Laura Vigil, Toni Zapata, Andrea Grau, Marta Bonet, Montserrat Montaña, María Piñar

“…Despite these obstacles, AI and Big Data have the potential to transform medical care for sleep disorders, improving both diagnosis and treatment adherence, provided regulatory and cultural barriers are overcome.…”
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Production of giant gourami Osphronemus goramy Lac. juvenile with different rate of water exchange by Tatag Budiardi, Rona Albrettico Nemanita Ginting, Yani Hadiroseyani

“…Water quality management through a proper water exchange both in quantity and quality can be one of the alternatives to support the elevating production. …”
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