Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine by Marina Agueda-Oyarzabal, Marie S. Isidor, Kaja Plucińska, Lars R. Ingerslev, Oksana Dmytriyeva, Patricia S.S. Petersen, Sara Laftih, Axel B. Pontoppidan, Jo B. Henningsen, Kaja Rupar, Erin L. Brown, Thue W. Schwartz, Romain Barrès, Zachary Gerhart-Hines, Camilla C. Schéele, Brice Emanuelli

Get full text

Effect of Chinese herbal tea in the treatment of throat pain and swelling after anterior cervical spine surgery (中药代茶饮治疗颈椎前路术后咽喉部肿痛效果观察) by KANG Jingjing (康京京), DU Jian (杜渐), ZHANG Zhe (张喆), LI Huibin (李会斌), DU Li (杜丽), SUN Feifei (孙飞飞)

“…Methods Totally 80 patients undergoing anterior cervical spine surgery were randomly divided into the control group and the observation group, with 40 cases in each group. Both the groups received routine treatment and nursing after surgery, and the observation group was given additional treatment of Chinese herbal tea. …”
Get full text

Pengembangan Aplikasi Sistem Informasi Pendataan Bangunan (SIPBANG) pada Dinas Pekerjaan Umum dan Penataan Ruang (DPUPR) Kota Malang Menggunakan Framework Scrum by Muhamad Rifky, Yusi Tyroni Mursityo, Bondan Sapta Prakoso

“…Dinas Pekerjaan Umum dan Penataan Ruang (DPUPR) Kota Malang adalah organisasi yang mengatur terkait perencanaan kawasan, infrastruktur, bangunan, dan lainnya. …”
Get full text

Barriers and drivers to COVID-19 protective behaviours of forcibly displaced myanmar nationals (FDMN)/ rohingya refugees in Cox's bazar, Bangladesh: A scoping review by Sarah Reda, Zarah Yusuf, Basel Karo, Balwinder Singh Chawla, Andreas Jansen, Saskia Lange, Jorge Martinez, Emily Dorothee Meyer, Julia Neufeind, Aarti Shrikrishana Singh, Elisa Wulkotte, Cath Jackson

“…Barriers and drivers to these behaviors spanned all four COM factors reflecting both individual and environmental influences. Most frequently cited barriers and drivers were found in the motivation (e.g. belief, fear, trust) and physical opportunity (e.g. information, the physical camp environment) factors. …”
Get full text

A CO₂–Δ¹⁴CO₂ inversion setup for estimating European fossil CO₂ emissions by C. Gómez-Ortiz, G. Monteil, G. Monteil, S. Basu, S. Basu, M. Scholze

“…Finally, having a good prior estimate of the terrestrial isotopic disequilibrium is important to avoid introducing additional noise into the posterior fossil <span class="inline-formula">CO₂</span> fluxes.…”
Get full text

Modeling Factors Influencing Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…ObjectiveProject financing has emerged as a critical mechanism for funding infrastructure and capital-intensive projects across various sectors, both in the public and private domains. Its significance has grown notably in recent decades within the financial market, reflecting its pivotal role in facilitating economic development. …”
Get full text

TGFβ1 Restores Energy Homeostasis of Human Trophoblast Cells Under Hyperglycemia In Vitro by Inducing PPARγ Expression, AMPK Activation, and HIF1α Degradation by Nihad Khiat, Julie Girouard, Emmanuelle Stella Kana Tsapi, Cathy Vaillancourt, Céline Van Themsche, Carlos Reyes-Moreno

“…Treatment with TGFβ1 appears to counteract this trend, probably by enhancing both glycolytic and mitochondrial metabolism, suggesting a potential regulatory role of TGFβ1 in placental trophoblast cell glucose metabolism.…”
Get full text

CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…IntroductionAccurately assessing biofilm viability is essential for evaluating both biofilm formation and the efficacy of antibacterial treatments. …”
Get full text

Optimized Type-2 Fuzzy Logic Control for Low-Speed Vehicle Pedal Pressing Automation Using Hybrid Spiral Sine Cosine Algorithm by Azrul Azim Abdullah Hashim, Nor Maniha Abdul Ghani, Salmiah Ahmad, Mohd Ruzaini Hashim, Noor Zirwatul Ahlam Naharuddin, Addie Irawan

“…The research investigates two FLC approaches: the standard Type 1 FLC and the advanced Type 2 FLC, both optimized using the Hybrid Spiral Sine Cosine Algorithm (SSCA). …”
Get full text

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity by Claire E. Otero, Sophia Petkova, Martin Ebermann, Husam Taher, Nessy John, Katja Hoffmann, Angel Davalos, Matilda J. Moström, Roxanne M. Gilbride, Courtney R. Papen, Aaron Barber-Axthelm, Elizabeth A. Scheef, Richard Barfield, Lesli M. Sprehe, Savannah Kendall, Tabitha D. Manuel, Teresa Beechwood, Linh Khanh Nguyen, Nathan H. Vande Burgt, Cliburn Chan, Michael Denton, Zachary J. Streblow, Daniel N. Streblow, Alice F. Tarantal, Scott G. Hansen, Amitinder Kaur, Sallie Permar, Klaus Früh, Hartmut Hengel, Daniel Malouli, Philipp Kolb

“…When RhCMV-naïve male rhesus macaques were infected with vFcγR-deleted RhCMV, peak plasma DNAemia levels and anti-RhCMV antibody responses were comparable to wildtype infections of both male and female animals. However, the duration of plasma DNAemia was significantly shortened in immunocompetent, but not in CD4 + T cell-depleted animals. …”
Get full text

The Effect of Chewing Simulation on Flexural Strength of Different Lithium Disilicate Ceramics by Alsulimani O, Yousief SA, Al-Dabbagh RA, Attar EA, Bukhary DM, Algamaiah H, Musawa K, Subahi A, Abuzinadah SH, Alhaddad AJ, Alqahtani WMS, Emam ANM, Alqhtani MA, Elmarakby AM

“…Osamah Alsulimani,1 Salah A Yousief,2,3 Raghad A Al-Dabbagh,4 Esraa A Attar,4 Dalea M Bukhary,4 Hamad Algamaiah,5 Khadija Musawa,6 Awatif Subahi,6 Samar H Abuzinadah,7 Abdulrahman J Alhaddad,4 Waleed MS Alqahtani,8 Abdel Naser M Emam,9 Mohammad A Alqhtani,9 Ahmed M Elmarakby2,10 1Department of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Restorative and Prosthetic Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, 13313, Saudi Arabia; 3Department of Crown and Bridge, Faculty of Dental Medicine, Al-Azhar University, Assuit, Egypt; 4Department of Oral and Maxillofacial Prosthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 5Department of Restorative Dental Science, King Saud University, College of Dentistry, Riyadh, Saudi Arabia; 6BDS, General Dentist, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 7Department of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 8Department of Prosthetic Dentistry, College of Dentistry, King Khalid University, Abha, Saudi Arabia; 9Department of Prosthetic Dental Science, Faculty of Dentistry, Najran University, Najran, Saudi Arabia; 10Department of Operative Dentistry, Faculty of Dental Medicine, Al-Azhar University, Assuit, EgyptCorrespondence: Salah A Yousief, Department of Restorative and Prosthetic Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, 13313, Saudi Arabia, Tel +966598045800, Email Salah.a@dau.edu.saBackground: Improved Lithium Disilicate Ceramic has been highly valued in dentistry for over two decades, owing to its durability and aesthetic qualities, making it a preferred choice for both anterior and posterior crowns.Objective: This study aimed to evaluate the flexural strength of two types of lithium disilicate blocks post-chewing simulation.Materials and Methods: Seventy-six lithium disilicate specimens were utilized in this study. …”
Get full text

Associations of fasting plasma glucose and glycosylated hemoglobin levels at less than 24 weeks of gestation with hypertensive disorders of pregnancy: the BOSHI study by Seiya Izumi, Noriyuki Iwama, Hirotaka Hamada, Taku Obara, Mami Ishikuro, Michihiro Satoh, Takahisa Murakami, Masatoshi Saito, Takayoshi Ohkubo, Takashi Sugiyama, Shinichi Kuriyama, Nobuo Yaegashi, Kazuhiko Hoshi, Yutaka Imai, Hirohito Metoki, the BOSHI Study Group

“…When the participants were divided into two categories based on the cut-off value with the maximum Youden Index of FPG or HbA1c, the ORs for high FPG (≥84 mg/dL) or high HbA1c (≥5.2% [33 mmol/mol]) were 1.223 (95% CI: 1.000–1.496) and 1.392 (95% CI: 1.122–1.728), respectively. When both FPG and HbA1c were included in the model simultaneously, the statistical significance of Q4 of FPG disappeared, whereas that of HbA1c remained. …”
Get full text

Accuracy of ESAT6-CFP10 skin test compared with tuberculin skin test in a healthy population: a randomized, blind, parallel controlled phase III clinical study by Xiaoyan Ding, Weixin Du, Qiao Liu, Lifeng Tao, Yan Shao, Peng Lu, Huaiyu Yang, Xiaoxue Teng, Cheng Chen, Zhongqi Li, Jinbiao Lu, Aihua Zhao, Guozhi Wang, Miao Xu, Limei Zhu

“…The positivity rates and concordance of the three tests were calculated in both stages, and a logistic regression model was constructed to determine the factors influencing the booster effect of EC in the second stage. …”
Get full text

Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307 by Jie Sheng, Rory Cave, Mary M. Ter-Stepanyan, Siyu Lu, Yingxiong Wang, Taihang Liu, Hermine V. Mkrtchyan

“…Specifically, isolates designated as ARM03 and ARM06 were resistant to piperacillin-tazobactam, ARM04 and ARM05 had intermediate resistance to both piperacillin-tazobactam and imipenem, and ARM03 showed intermediate resistance to amikacin. …”
Get full text

The report of Chief of the General Staff of USSR marshal Alexander Jegorov about his visit in Lithuania, Latvia, and Estonia on 15th-26th of February, 1937 by Zenonas Butkus, Magnus llmjarv

“…Jegorov's assessment of the Lithuanian armed forces was more critical and less favourable than that of its both Northern neighbours. The published source supplements and adjusts the existing data related to the relations between the Baltic States and the USSR. …”
Get full text

PHARAOH: A collaborative crowdsourcing platform for phenotyping and regional analysis of histology by Kevin Faust, Min Li Chen, Parsa Babaei Zadeh, Dimitrios G. Oreopoulos, Alberto J. Leon, Ameesha Paliwal, Evelyn Rose Kamski-Hennekam, Marly Mikhail, Xianpi Duan, Xianzhao Duan, Mugeng Liu, Narges Ahangari, Raul Cotau, Vincent Francis Castillo, Nikfar Nikzad, Richard J. Sugden, Patrick Murphy, Safiyh S. Aljohani, Philippe Echelard, Susan J. Done, Kiran Jakate, Zaid Saeed Kamil, Yazeed Alwelaie, Mohammed J. Alyousef, Noor Said Alsafwani, Assem Saleh Alrumeh, Rola M. Saleeb, Maxime Richer, Lidiane Vieira Marins, George M. Yousef, Phedias Diamandis

“…Moreover, by using our PHARAOH pipeline, we showcase how correlation of cohort-level cytoarchitectural features with accompanying biological and outcome data can help systematically devise interpretable morphometric models of disease. Both the custom model design and feature extraction pipelines are amenable to crowdsourcing, positioning PHARAOH to become a fully scalable, systems-level solution for the expansion, generalization and cataloging of computational pathology applications.…”
Get full text

Determining dry oak lumber consumption for the production of solid edge-glued panels by Volodymyr Mayevskyy, Rostislav Moroz, Serhiy Kopynets, Oleh Ferents, Roman Shchupakivskyy, Yevstakhii Myskiv

“…Solid edge-glued panels of Ukrainian enterprises are manufactured both for sale on domestic and foreign markets, as well as for the production of their own products. …”
Get full text

Ethnic and racial discrimination in maternal health care in Mexico: a neglected challenge in the search for universal health coverage by Edson Serván-Mori, Sergio Meneses-Navarro, Rocío García-Díaz, Diego Cerecero-García, David Contreras-Loya, Octavio Gómez-Dantés, Arachu Castro

“…Addressing these inequities requires the recognition of both observable and unobservable factors driven by discriminatory ideologies and the implementation of targeted measures to confront the complex interactions driving discrimination in maternal health care services for Indigenous women.…”
Get full text

A Prospective Randomized Trial Comparing 2 Different Paclitaxel-Coated Balloons in De Novo Coronary Artery Disease by Eun-Seok Shin, MD, PhD, Yongwhi Park, MD, PhD, Jong-Young Lee, MD, PhD, Ae-Young Her, MD, PhD, Min-Ku Chon, MD, PhD, Sunwon Kim, MD, PhD, Seung-Woon Rha, MD, PhD, Gyu Chul Oh, MD, PhD, Deok-Kyu Cho, MD, PhD, Bitna Kim, MS, Jang-Whan Bae, MD, PhD

“…There was comparable late lumen enlargement (44.7% vs 42.7%; P = 0.903) and binary restenosis rates (3.2% vs 6.7%; P = 0.442) following treatment with shellac and vitamin E-based PCB and reference PCB, respectively. Both PCBs had similar 12-month rates of target vessel failure (3.0% in shellac and vitamin E-based PCB vs 4.3% in reference PCB; P = 0.921). …”
Get full text

Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models by Shohei Koyama, Yujiro Naito, John D Minna, David E Gerber, Ryan R Kowash, Manoj Sabnani, Laura T Gray, Qing Deng, Nusrat U A Saleh, Luc Girard, Kentaro Masahiro, Zhiqian Lucy Liu, Hemanta Baruah, Esra A Akbay

“…Cell surface expression of MICA/B in NSCLC cell lines was determined through flow cytometry while ligand shedding in both patient blood and cell lines was determined through ELISA. …”
Get full text