Enriched environment rescues bisphenol A induced anxiety-like behavior and cognitive impairment by modulating synaptic plasticity by Jiong Li, Guangyin Yu, Laijian Wang, Wenjun Zhang, Wenya Ke, Yifei Li, Danlei Liu, Keman Xie, Yuanyuan Xu, Caihui Cha, Guoqing Guo, Jifeng Zhang

“…Furthermore, exposure to BPA led to a decrease in both the density and maturity of dendritic spines, as well as a reduction in neurite length and branch numbers. …”
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The Effect of Alkyl Substituents on the Formation and Structure of Homochiral (<i>R</i>*,<i>R</i>*)-[R₂Ga(<i>µ</i>-OCH(Me)CO₂R′)]₂ Species—Towards... by Magdalena Kaźmierczak, Łukasz Dobrzycki, Maciej Dranka, Paweł Horeglad

“…With an increase in the bulkiness of alkyl substituents on gallium the following can be observed: (a) the tendency for the formation of homochiral complexes decreased, (b) the symmetry of homochiral (<i>S</i>,<i>S</i>)-[R₂Ga(<i>µ</i>-OCH(Me)CO₂Me]₂ (M = Me, Et (<i>S</i>,<i>S</i>)-<b>1</b>), <i>ⁱ</i>Pr (<i>S</i>,<i>S</i>)-<b>2</b>) changed, and both have resulted in (c) lower or no heteroselectivtity across these complexes in the ROP of <i>rac</i>-LA. …”
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High-performance laser speckle contrast image vascular segmentation without delicate pseudo-label reliance by Shenglan Yao, Huiling Wu, Suzhong Fu, Shuting Ling, Kun Wang, Hongqin Yang, Yaqin He, Xiaolan Ma, Xiaofeng Ye, Xiaofei Wen, Qingliang Zhao

“…Our study has the potential to efficiently segment and evaluate blood vessels in both normal and disease situations. This would greatly benefit future research in life and medicine.…”
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Gualou Guizhi Granule inhibits microglia-mediated neuroinflammation to protect against neuronal apoptosis in vitro and in vivo by Xuezhen Li, Han Huang, Yanan Li, Yi Feng, Jinxuan Wang, Shuping Luo, Yaping Chen, Yuqin Zhang, Guohong Yan, Lihong Nan

“…Additionally, we investigated the effects of GLGZG in combination with N-[N-[3,5-difluorophenacetyl]-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) or siRNA-Notch1 to further elucidate the involvement of the Notch signaling pathway.ResultsGLGZG significantly inhibited microglia activation and reduced neuroinflammation by de-creasing the levels of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α in both in vitro and in vivo models. GLGZG also effectively protected against microglia-induced neuronal apoptosis. …”
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Comparison of the mid-infrared spectra and prediction equations developed from morning and evening milk samples from twice-a-day milked dairy cows by M. Frizzarin, E. Hayes, A. Casa, D.P. Berry

“…ABSTRACT: Mid-infrared spectroscopy is a technology used globally for quantifying the concentration of fat, protein, lactose, and other constituents in the milk samples of both individual animals and bulk tank milk. Differences in the milk components and yield of cows are known to exist between morning and evening milk; nonetheless, differences in the spectra originating from the same cow from morning and evening milkings have never been investigated. …”
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Guidance and Counselling and Learners’ Discipline in Kasese District: A Case of Selected Government-Aided Secondary Schools in Bukonzo County. by Kule, Samson

“…Skinner (1938) observed that good behaviour is reinforced through rewards while bad behaviour is weakened through punishment. 3. …”
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Guidance and Counselling and Learners’ Discipline in Kasese District: A Case of Selected Government-Aided Secondary Schools in Bukonzo County. by Kule, Samson

“…Skinner (1938) observed that good behaviour is reinforced through rewards while bad behaviour is weakened through punishment. 3. …”
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Effects of Teenage Pregnancy on Girl Child Education in Buhunga Sub-County Uganda. by Twikirize, Edwig

“…Data collection instruments were structured questionnaires and interviews to collect data on the effects of teenage pregnancy on Girl Child Education in Buhunga Sub-County of Rukungiri District, Uganda. Both qualitative and quantitative data were collected. …”
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The Effect of Corona Dormancy on the Physiological Stress and Main Nutritional Components in the Transport of Trachinotus ovatus During Survival by Siwei LIU, Jiamei ZHONG, Xiuping FAN, Xiaoming QIN, Jian SHEN, Wenqi XU

“…To solve the above problems, chemical anesthesia, physical dormancy, and other methods are generally used to improve the survival rate of fish and maintain good nutritional quality in the process of keeping them alive and for transportation. …”
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CircUCK2(2,3) promotes cancer progression and enhances synergistic cytotoxicity of lenvatinib with EGFR inhibitors via activating CNIH4–TGFα–EGFR signaling by Xindong Wei, Anfeng Si, Shuai Zhao, Yi Fu, Jilei Li, Kedeerya Aishanjiang, Yujie Ma, Chang Yu, Bo Yu, Chunhong Cui, Hui Wang, Xianming Kong, Shibo Li, Xiaoni Kong, Ying Tong, Hailong Wu

“…Functionally, circUCK2(2,3) enhances HCC proliferation, migration, and invasion, both in vitro and in vivo. Mechanistically, by sponging miR-149-5p, circUCK2(2,3) increases CNIH4 levels, which in turn amplifies TGFα secretion, resulting in the activation of EGFR and downstream pAKT and pERK signaling pathways. …”
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Patient-centred care and quality of life and hope among Japanese patients receiving home medical care: a multicentre, cross-sectional study by Nobuhiro Ikeda, Michiko Hinata, Noriaki Kurita, Tomoka Nakamura, Takashi Fujii, Chihiro Tsuchiya, Yukio Tsugihashi, Hidekazu Iida, Shinu Hayashi, Masakazu Yasunaka, Misaki Hirose, Yutaka Shirahige, Shinsuke Muto, Tatsunobu Natsubori, Wataru Nakagawa, Akihiko Yonenaga, Lina Inagaki, Shioto Itakura, Naoya Miyashita, Takuya Furugen, Takafumi Abo, Sadayuki Okudaira, Kazuhiko Takuma, Masahiro Deguchi, Yoshitaka Harada, Seiji Matsuo, Motomichi Nakagawa, Ken Tanigawa, Yoshio Ochi, Sadanobu Ogasawara, Kazuhiko Hoshino, Momoko Aruga, Yoshinori Nakamura, Nobuhiro Sawa, Yosuke Akashi, Nobuyuki Miyagi, Toyohiro Terasaki, Kunihiro Kinoshita, Masaji Kikukawa, Hisakazu Kato, Masayuki Amano, Kentaro Asakura, Naoto Fukui

“…This study examined the association between the quality of patient-centred care and both QOL and hope.Design Multicentre, cross-sectional study.Setting Twenty-nine home care clinics in the Tokyo Metropolitan Area, Nara Prefecture and Nagasaki Prefecture in Japan.Participants 200 patients receiving home medical care.Exposure Patient-centredness was measured using the Japanese version of the Primary Care Assessment Tool-Short Form (JPCAT-SF).Outcome measures The primary outcome measures were QOL, assessed using the QOL-Home Care (QOL-HC) scale, and hope, measured using the Health-Related Hope (HR-Hope) scale. …”
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Prevalence and predictors of permanent pacemaker implantation in patients with aortic stenosis undergoing transcatheter aortic valve implantation: a prospective cohort study by Erlend Eriksen, Ronak Rajani, Sahrai Saeed, Svein Rotevatn, Daanyaal Wasim, Øyvind Bleie, Abukar Mohamed Ali, Erik Jerome Stene Packer, Håvard Keilegavlen

“…The type of bioprosthesis, but not size, was associated with permanent pacemaker implantation (mechanically expandable valves OR 3.48, 95% CI 2.16 to 5.59; balloon-expandable valves OR 0.07, 95% CI 0.02 to 0.29, both p&lt;0.001)—irrespective of age and sex. During a median follow-up of 60.4 months (range 3–131 months), permanent pacemaker implantation following TAVI was not associated with all-cause mortality (HR 0.89; 95% CI 0.69 to 1.16, p=0.403).Conclusions In the current study, the rates of permanent pacemaker implantation following TAVI decreased substantially from the early low-volume phase to the late high-volume phase. …”
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The role of nutrient availability and resorption efficiency and their impact on nutrient conservation in mangroves by M.E.B. Gerona-Daga, R.A. MacKenzie, L.G. Sumabat-Dacones, C.F.P. Naputo, S.G. Salmo III

“…This study aims to investigate the changes in soil and leaf nutrient concentrations of nitrogen and phosphorus, leaf nitrogen to phosphorus ratio, nitrogen and phosphorus resorption efficiencies, and nitrogen resorption efficiency to phosphorus resorption efficiency ratio across a chronosequence of restored and recolonized stands (with intact natural stands as reference sites) in Ormoc Bay, Philippines.METHODS: Soil and leaf samples were obtained from both seedlings and mature trees across each vegetation plot in restored, recolonized, and natural stands, totaling 30 plots. …”
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Creating pathways for collaboration between Argentina and the UK to utilise microbial biofilms in sustainable agriculture by Patricia L. Abdian, Miguel Cámara, Fabricio D. Cassan, Gabriel Castrillo, Marisa Díaz, Gustavo Gonzalez Anta, Claire Hodge, Jo Slater-Jefferies, Cait E. MacPhee, Enzo Moriconi, Paulina D. Rakowska, Rasmita Raval, Duncan Ross, Juan F. Sandoval, Diego O. Serra, Claudio Valverde, Jeremy Webb, Ana Winters

“…Commitment from the governments and support from funding bodies in both countries will be essential for the establishment of robust research programmes and long-term successful collaborations between researchers, industry and end users. …”
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Traumatic Bladder Ruptures: A Ten-Year Review at a Level 1 Trauma Center by John Barnard, Tyler Overholt, Ali Hajiran, Chad Crigger, Morris Jessop, Jennifer Knight, Chad Morley

“…AUA Urotrauma Guidelines suggest that urethral catheter drainage is a standard of care for both extraperitoneal and intraperitoneal bladder rupture regardless of the need for surgical repair. …”
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Presentations on How to Finance Iran's Higher Education Based on the Global Study Model by Ehsan Ehteshamnejad, Mehdi Pakzad Bonab, Mehdi Ramezani

“…Among the questions that are searched according to the results of this research, they are answered.Materials and Methods  In this research, both the documentary research method (books, articles, authoritative magazines, etc.) in English and Farsi, and a researcher-made questionnaire were used to implement the KAP model. …”
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Rapid inference of antibiotic susceptibility phenotype of uropathogens using metagenomic sequencing with neighbor typing by Amanda C. Carroll, Leanne Mortimer, Hiren Ghosh, Sandra Reuter, Hajo Grundmann, Karel Brinda, William P. Hanage, Angel Li, Aimee Paterson, Andrew Purssell, Ashley Rooney, Noelle R. Yee, Bryan Coburn, Shola Able-Thomas, Martin Antonio, Allison McGeer, Derek R. MacFadden

“…Methods to quickly and accurately predict susceptibility phenotypes for pathogens causing UTI could thus improve both patient outcomes and antibiotic stewardship. …”
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Att lära om naturen från naturen och i naturen by Sara Planting-Bergloo, Emma Rova, Charlotte Lennartsdotter, Per Rohlin, Maria Andrée

“…Fältundersökningar är alltså en central biologisk praktik som eleverna behöver möta för att utveckla förståelse för biologi som vetenskap. …”
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Qualitative Insights on Barriers to Receiving a Second Dose of Measles-Containing Vaccine (MCV2), Oromia Region of Ethiopia by Kalkidan Solomon, Brooke N. Aksnes, Abyot Bekele Woyessa, Chala Gari Sadi, Almea M. Matanock, Monica P. Shah, Paulos Samuel, Bekana Tolera, Birhanu Kenate, Abebe Bekele, Tesfaye Deti, Getachew Wako, Amsalu Shiferaw, Yohannes Lakew Tefera, Melkamu Ayalew Kokebie, Tatek Bogale Anbessie, Habtamu Teklie Wubie, Aaron Wallace, Ciara E. Sugerman, Mirgissa Kaba

“…However, the sub-optimal coverage of both MCV1 and MCV2 suggest challenges with vaccine uptake. …”
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Socioecological dynamics of diverse global permafrost-agroecosystems under environmental change by Melissa Ward Jones, Joachim Otto Habeck, Mathias Ulrich, Susan Crate, Glenna Gannon, Tobias Schwoerer, Benjamin Jones, Mikhail Kanevskiy, Prashant Baral, Amina Maharjan, Jakob Steiner, Andrew Spring, Mindy Jewell Price, David Bysouth, Bruce C. Forbes, Mariana Verdonen, Timo Kumpula, Jens Strauss, Torben Windirsch, Christopher Poeplau, Yuri Shur, Benjamin Gaglioti, Nicholas Parlato, Fulu Tao, Merritt Turetsky, Stephanie Grand, Adrian Unc, Nils Borchard

“…The exact locations and amount of agricultural production in areas containing permafrost are currently unknown, therefore we provide an overview of countries where both permafrost and agricultural activities are present. …”
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