Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study by Xiaomeng Yang, Zeyan Li, Lei Lei, Xiaoyu Shi, Dingming Zhang, Fei Zhou, Wenjing Li, Tianyou Xu, Xinyu Liu, Songyun Wang, Quan Yuan, Jian Yang, Xinyu Wang, Yanfei Zhong, Lilei Yu

“…The model demonstrating the optimal performance in both internal and external testing groups was selected to construct the HFpEF diagnostic model. …”
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'Which treatment do you believe you received?' A randomised blinding feasibility trial of spinal manual therapy by Javier Muñoz Laguna, Astrid Kurmann, Léonie Hofstetter, Emanuela Nyantakyi, Julia Braun, Lauren Clack, Heejung Bang, Mazda Farshad, Nadine E. Foster, Milo A. Puhan, Cesar A. Hincapié, the SALuBRITY Blinding Clinician Group

“…BIs among outcome assessors suggested adequate blinding at both study visits (active SMT: 0.08 [− 0.05 to 0.20] and 0.03 [− 0.11 to 0.16]; placebo SMT: − 0.12 [− 0.24 to 0.00] and − 0.07 [− 0.21 to 0.07]). …”
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Ionizable polymeric micelles (IPMs) for efficient siRNA delivery by Ziyu Zhou, Yu Feng, Mingzhou Jiang, Zijun Yao, Jing Wang, Feng Pan, Rulan Feng, Chong Zhao, Yinyu Ma, Jinge Zhou, Lei Sun, Xiaotian Sun, Changyou Zhan, Xiao He, Kuan Jiang, Jiahui Yu, Zhiqiang Yan

“…A fibroblast activation protein inhibitor modified IPMs (FAPi-IPMs) show higher targeting for activated hepatic stellate cells (HSCs) compared to that for hepatocytes, silencing both HSP47 and HMGB1, reducing collagen secretion and liver inflammation, thereby treating fibrosis. …”
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Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study by Ming-Li Chen, Jin Li, Kruthika R. Iyer, Catherine Tcheandjieu, Shirin Jimenez, Elias Levy Itshak Salfati, Liana C. Del Gobbo, Marcia L Stefanick, Manisha Desai, Xiaonan Xue, Themistocles L Assimes

“…A significant dose-response effect was observed for both physical activity and smoking and the reduction in absolute risk of presenting with fatal CHD associated with a healthy lifestyle was roughly equivalent to the difference in risk observed among women separated in age by approximately 10 years. …”
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Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association by V. T. Ivashkin, N. D. Yushchuk, I. V. Mayev, Tatyana L Lapina, Ye. A. Poluektova, O. S. Shifrin, A. S. Tertychny, A. S. Trukhmanov, A. A. Sheptulin, Ye. K. Baranskaya, O. S. Lyashenko, K. V. Ivashkin

“…Current epidemiologic trends of C. difficile-associated disease are characterized by growth of both inpatient and community-acquired morbidity, expansion of risk groups, increase in number of more severe cases including those, caused by more virulent BI/NAP1/027strain, tendency to relapsing, increase in lethal outcomes. …”
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Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients by Novaes-Gaeta Ludmila N., Moraes Mariele C., Katayama Keyla Y., Sangaletti Carine T., Irigoyen Maria Claudia, Freitas Sarah, Viana Ariane, de Angelis Katia, Caldini Elia G., Lopes Heno F.

“…Catalase increased in both groups; reduction of TBARs, FRAP and carbonyls occurred in the hypertensive group. …”
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Treatment patterns for chronic obstructive pulmonary disease under the tiered medical system by Xiaoli Wang, Xingru Zhao, Tianqi Cen, Yi Yu, Zhiwei Xu, Lijun Shen, Ziqi Wang, Paul Jones, Quncheng Zhang, Yunxia An, Xiaoju Zhang

“…This underscores the necessity for enhanced availability of medications and educational initiatives aimed at both physicians and patients within Tier1 hospitals.…”
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Synergistic effects of allantoin and Achyranthes japonica-biochar profoundly alleviate lead toxicity during barley growth by Ghulam Murtaza, Najmaldin Ezaldin Hassan, Muhammad Usman, Gang Deng, Zeeshan Ahmed, Javed Iqbal, Mohamed S. Elshikh, Humaira Rizwana, Basharat Ali, Rashid Iqbal, Maximilian Lackner

“…Lead (Pb), a toxic metal, causes severe health hazards to both humans and plants due to environmental pollution. …”
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Intravascular Imaging-Guided Percutaneous Coronary Intervention in Patients With End-Stage Renal Disease on Maintenance Dialysis by Chia-Pin Lin, MD, Fu-Chih Hsiao, MD, Ying-Chang Tung, MD, Tzyy-Jer Hsu, MD, Shing-Hsien Chou, MD, Yu-Sheng Lin, MD, Shao-Wei Chen, MD, PhD, Pao-Hsien Chu, MD

“…Conclusions: The number of PCI- and IVI-guided procedures has progressively increased in the past decade in Taiwan in both the general and ESRD populations. Among ESRD patients on maintenance dialysis, the clinical outcomes were comparable between OCT- and IVUS-guided PCI.…”
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Efficacy and Safety of HAPC in Barrett's Esophagus – A Multicenter Italian Prospective Study by Davide Massimi, Roberta Maselli, Silvia Pecere, Cristiano Spada, Gianluca Andrisani, Francesco Maria Di Matteo, Antonella La Terra, Franco Coppola, Antonio Capogreco, Roberto De Sire, Ludovico Alfarone, Maddalena Menini, Marco Spadaccini, Cesare Hassan, Alessandro Repici

“…All patients achieved both CE-IM and CE-D (51/51), requiring a mean of 1.51 (SD 0.83) sessions. …”
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Multidimensional 1-Year Outcomes After Intensive Care Admission for Multisystem Inflammatory Syndrome in Children by Thomas C. Seijbel, BSc, Levi Hoste, MD, Corinne M. P. Buysse, MD, PhD, Karolijn Dulfer, PhD, Filomeen Haerynck, MD, PhD, Matthijs de Hoog, MD, PhD, Naomi Ketharanathan, MD, PhD

“…This is the first 1-year outcome study of MIS-C PICU patients to include both physical and psychosocial characteristics. One year after PICU admission, most children had normalized functional performance as measured by three validated performance scores. …”
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Ameliorating potential effects of natural biological formulations and biostimulants on plant health and quality attributes in coriander-fenugreek intercropped strawberry (Fragaria... by Priya Thakur, Pramod Kumar, CL Sharma, Uday Sharma, Nisha Sharma, Tanzin Ladon

“…The positive influence both on leaf and fruit NPK contents were also recorded when plantlets were supplemented with GJ @100 g/m2 + JV@ 20% + Azolla @ 200 g/plant. …”
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Studying and enhancing the methods for distance teaching of computer science in Kazakh secondary school students during the pandemic by M. M. Zhamankarin, A. M. Sivinskiy, M. K. Aitkenova, M. B. Zhanibekov

“…The preliminary analysis of the quality of knowledge related to the discipline of computer science in the participants revealed generally high and average level of both acquisition of theoretical information and development of the subject-related skills, which was registered based of the results of in-person education. …”
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The Monocyte-to-Lymphocyte Ratio at Hospital Admission Is a Novel Predictor for Acute Traumatic Intraparenchymal Hemorrhage Expansion after Cerebral Contusion by Jiangtao Sheng, Tian Li, Dongzhou Zhuang, Shirong Cai, Jinhua Yang, Faxiu Ding, Xiaoxuan Chen, Fei Tian, Mindong Huang, Lianjie Li, Kangsheng Li, Weiqiang Chen

“…We constructed two predictive models: basic combined model of clinical and imaging variables and MLR combined model of both MLR and other variables in the basic model. …”
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Association between Corneal Stiffness Parameter at the First Applanation and Keratoconus Severity by Kaili Yang, Liyan Xu, Qi Fan, Shengwei Ren

“…SP-A1 was found to be statistically positively associated with intraocular pressure (IOP), biomechanical corrected IOP (bIOP), time from the initiation of air puff until the first applanation (A1T), corneal velocity at the second applanation (A2V), and negatively associated with deformation amplitude (DA), peak distance (PD), corneal velocity at the first applanation (A1V), time from the initiation of air puff until the second applanation (A2T), and DA Ratio Max [2 mm] both in normal and keratoconus eyes (all P<0.05). …”
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Hybrid precoding and power allocation for mmWave NOMA systems based on time delay line arrays by Gangcan SUN, Xinli WU, Wanming HAO, Zhengyu ZHU

“…Specifically,the Dinkelbach method is applied in the outer layer to transform the fractional structure of the objective function in EE optimization into a subtractive structure, and the non-convex objective function is transformed into a convex function by using mathematical tools in the inner layer, and then an iterative algorithm based on alternating optimization (AO) is proposed for power allocation, and finally the solution of the initial problem is obtained by circular iteration in both inner and outer layers. Results:Simulation analysis:(1)The figure6(a)show that the SE of the proposed scheme is higher than that of the conventional phase-shifter modulation network with fully-connected and sub-connected hybrid precoding structures; In addition, the system SE of the fullconnected structure under the proposed scheme is better than that of the hybrid-connected and sub-connected structures.(2) the figure6(b) show that the EE of the system under the proposed scheme is also better than that of the conventional phase-shifter network-based and fully-digital precoding structures; Also, the system SE of the sub-connected structure under the proposed scheme is better than that of the hybrid-connected and fully-connected structures. (3) The figure7(a) show that the SE of the system increases as the number of antennas increases;The figure7(b)show that the EE of the system decreases as the number of antennas increases. (4) The figure8(a) and (b) show that compared with the mmWave orthogonal multiple access (OMA) system based on the time-delayed line array, and the proposed scheme can achieve better performance in terms of EE and SE.(5)the figure9(a) show that the performance of the proposed improved K-means user grouping algorithm is better than the K-means user grouping algorithm.Although the K-means can be done better based on the state information of the channel,the randomness of its initial cluster head will affect the convergence of the algorithm and the system performance. …”
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Structure-Function Relationship between Cluster Mean Defect and Sector Peripapillary Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma by Jing Han, Wenjiu Yang, Dabo Wang, Haiqing Bai

“…For the cluster–sector pair that could be fitted by both models, Wilcoxon signed rank test of absolute residuals was used to compare the goodness of fit. …”
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Comparing the Institution-based Supervision and Tele-based Supervision for Task-oriented Exercises on Upper Limb Motor Performance and Functional Ability among Stroke Patients: A R... by Neha, Subhasish Chatterjee

“…Group B will receive institution-based supervision for task-oriented exercises, whereas Group A will receive tele-based supervision for live sessions. Both groups will perform task-oriented exercises for 30 minutes, three days a week for eight weeks. …”
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Alternations of the gut microbiota and the Firmicutes/Bacteroidetes ratio after biologic treatment in inflammatory bowel disease by Yu-Chieh Tsai, Wei-Chen Tai, Chih-Ming Liang, Cheng-Kun Wu, Ming-Chao Tsai, Wan-Hsiang Hu, Pao-Yuan Huang, Chien-Hung Chen, Yuan-Hung Kuo, Chih-Chien Yao, Seng-Kee Chuah

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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…MicroRNAs (miRNAs), a class of endogenous non-coding RNAs with post-transcriptional regulatory properties, are known to play a major role in retinal function, both in physiological and pathological conditions. …”
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