Toward a circular carbon economy: Production of green C1 compounds through high-temperature CO2 electrolysis by Nan Zheng, Jing Zhu, Haitao Zhu, Jin Xuan, Haoran Xu, Meng Ni

“…Within this context, single-carbon compounds are of particular interest due to their extensive applications as both chemical precursors and fuels. This review summarizes recent advancements in the conversion of CO2 to green methane and methanol through high-temperature electrolysis pathways. …”
Get full text

Generation of novel oncolytic vaccinia virus with improved intravenous efficacy through protection against complement-mediated lysis and evasion of neutralization by vaccinia virus... by Dong-Sup Lee, Mi-Ju Park, Namhee Lee, Yun-Hui Jeon, Jiyoon Yoo, Suk-kyung Shin, Songyi Lee, Byung-Jin Jung, Yun-Kyoung Hong, Keunhee Oh

“…Background Oncolytic virus immunotherapy has revolutionized cancer immunotherapy by efficiently inducing both oncolysis and systemic immune activation. Locoregional administration has been used for oncolytic virus therapy, but its applications to deep-seated cancers have been limited. …”
Get full text

Artificial intelligence-assisted clinical decision support for childhood asthma management: A randomized clinical trial. by Hee Yun Seol, Pragya Shrestha, Joy Fladager Muth, Chung-Il Wi, Sunghwan Sohn, Euijung Ryu, Miguel Park, Kathy Ihrke, Sungrim Moon, Katherine King, Philip Wheeler, Bijan Borah, James Moriarty, Jordan Rosedahl, Hongfang Liu, Deborah B McWilliams, Young J Juhn

“…<h4>Trial registration</h4>ClinicalTrials.gov Identifier: NCT02865967.…”
Get full text

Analysis of cervical and breast cancer screening behavior and its influencing factors among urban and rural women in Beijing. by Yanqing Gao, Guoxin Liang, Chun Chang, Feng Pan, Fumin Huang, Litong Gong, Liyu Huang

“…<h4>Results</h4>The sample size of the final included valid analysis was 3861 people, and the screening rate was 27.25% for cervical cancer, 20.64% for breast cancer, 30.46% for at least one screening and 17.43% for both cervical cancer and breast cancer screening. …”
Get full text

Real-world treatment patterns and clinical characteristics in patients with moderate-to-severe systemic lupus erythematosus: an analysis of the SLE Prospective Observational Cohort... by Raj Tummala, Richard A Furie, Laurent Arnaud, Eric F Morand, Martin Aringer, Stephanie Chen, Barnabas Desta, Alberta Hoi, Bo Ding, Christine Peschken, Jonatan Hedberg, Tina Grünfeld Eén, Alessandro Sorrentino, Danuta Kielar

“…In subgroup analyses, patients with high IFNGS and high disease activity state (HDAS) at baseline used more immunosuppressants and glucocorticoids compared with those with low IFNGS and non-HDAS at baseline.Conclusions These findings underscore that SLE therapy is still often unable to reach goals as recommended by the European Alliance of Associations for Rheumatology, both with regard to glucocorticoid use and disease activity, suggesting that there is an unmet need for new treatment options for patients with SLE.Trial registration number NCT03189875; 16 June 2017.…”
Get full text

Land use variation impacts on trace elements in the tissues and health risks of a commercial fish by N.D. Takarina, O.M. Chuan, T.G. Pin, I. Femnisya, A. Fathinah, A.N.B. Ramadhan, R. Hermawan, A. Adiwibowo

“…The result shows that the digestive tract consistently has the highest heavy metal levels compared to other tissues in both locations. Heavy metal in muscle has the lowest level. …”
Get full text

Effects of Electroacupuncture at Fengchi Acupoint on Myosatellite Cells and TLR4/MyD88/NF-κB Signaling Pathway in Chronic Cervical Muscle Injury Rats by HUANG Yuting, CHEN Jiayan, KAN Yu, FANG Yanping, WANG Jinwei, ZHENG Linyao, JING Xianghong, LIAO Jun

“…The EA group received electroacupuncture at Fengchi acupoint on both sides, 25 min each time, once a day, for 10 consecutive days as one course of treatment, with an interval of two days between courses of treatment, for 2 courses of treatment. …”
Get full text

Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study by Roberta Bevilacqua, Elvira Maranesi, Marco Benadduci, Gabriella Cortellessa, Alessandro Umbrico, Francesca Fracasso, Giovanni Melone, Arianna Margaritini, Angela La Forgia, Pierpaolo Di Bitonto, Ada Potenza, Laura Fiorini, Carlo La Viola, Filippo Cavallo, Alessandro Leone, Andrea Caroppo, Gabriele Rescio, Mauro Marzorati, Amedeo Cesta, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Lorena Rossi

“…ResultsStatistical analysis reveals a significant difference on the Performance-Oriented Mobility Assessment scale, both on balance and gait aspects, together with improvements in Short Physical Performance Battery, Unified Parkinson Disease Rating Scale–III, and Timed Up and Go test, underlying the usefulness of the rehabilitation intervention on the motor symptoms of PD. …”
Get full text

Interactive effect of phenylalanine with duration of diabetes on the risk of small vessel disease in Chinese patients with T2DM by Jun Zheng, Wei Zhang, Yu-Yang Miao, Xue-Rui Li, Wei-Ming Luo, Xi-Lin Yang, Zhong-Ze Fang, Qiang Zhang

“…SVD was defined as patients with diabetic nephropathy (DN) or diabetic retinopathy (DR) alone, or both. Serum amino acids were measured by mass spectrometry (MS) technology. …”
Get full text

Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives by Ekaterina M. Zhidkova, Evgeniya S. Oleynik, Ekaterina A. Mikhina, Daria V. Stepanycheva, Diana D. Grigoreva, Lyubov E. Grebenkina, Kirill V. Gordeev, Ekaterina D. Savina, Andrey V. Matveev, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya

“…The other compound with high GR affinity, 2-(hexylamino)-1-(4-nitrophenyl)ethanol (<b>13S-G2</b>), demonstrated cytotoxicity in both cell lines at concentrations of 50–70 µM. Overall, our results may provide a solid rationale for developing and further investigating synephrine derivatives as SEGRAs with anti-cancer activity.…”
Get full text

A latent class assessment of healthcare access factors and disparities in breast cancer care timeliness. by Matthew R Dunn, Didong Li, Marc A Emerson, Caroline A Thompson, Hazel B Nichols, Sarah C Van Alsten, Mya L Roberson, Stephanie B Wheeler, Lisa A Carey, Terry Hyslop, Jennifer Elston Lafata, Melissa A Troester

“…Variable travel (short travel to diagnosis but long travel to surgery) was associated with delayed treatment in the entire study population (RFDadj = 10.7%, 95% CI [2.7 to 18.8]) compared to the short travel, high use referent group. Long travel to both diagnosis and surgery was associated with delayed treatment only among black women. …”
Get full text

Validation study of synthetic models for esophageal atresia with tracheoesophageal fistula (EA/TEF): A simulation-based training in pediatric surgery by Zahradníková Petra, Hnilicová Silvia, Lindák Martin, Pechanová Rebeka, Števková Dominika, Vitovič Pavol, Laurovičová Miroslava, Horn František, Tvrdoň Tomáš, Babala Jozef

“…Background: Pediatric surgery is a highly specialised field, with minimally invasive surgery (MIS) posing greater technical challenges than conventional open surgery. Proficiency requires both in and out-of-operating-room training, with simulation playing a crucial role. …”
Get full text

Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study by Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X

“…Patients who underwent both tNGS and conventional microbiologic tests (CMTs) were grouped into the tNGS group, the others were divided into the mNGS group. …”
Get full text

The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy by Boning Cao, Zhendong Guo, Dan-Ting Li, Le-Ying Zhao, Zhen Wang, Ya-Bin Gao, Yao-Xian Wang

“…This study highlights a significant association between the stress hyperglycemia ratio (SHR) and both all-cause and cardiovascular mortality in patients with diabetic kidney disease (DKD) or chronic kidney disease (CKD). …”
Get full text

The Prevalence of Celiac Disease-Specific Auto-Antibodies in Type 1 Diabetes in a Moroccan Population by Ider Oujamaa, Majda Sebbani, Lahcen Elmoumou, Aïcha Bourrahouate, Rabiy El Qadiry, Soufian El Moussaoui, Imane Ait Sab, Mohamed Sbihi, Laila Ennazk, Ghizlane El Mghari-Tabib, Nawal El Ansari, Hicham Baizri, Mohamed Amine, Brahim Admou

“…Eight cases displayed low titers of IgA-tTGA, among which 4 were positive for HLA-DQ2, 1 for HLA-DQ8, and 1 for both DQ2 and DQ8. The other 2 cases had a biopsy-proven CD. …”
Get full text

Intestinal Microbiome Changes in Fecal Microbiota Transplant (FMT) vs. FMT Enriched with Lactobacillus in the Treatment of Recurrent Clostridioides difficile Infection by Elvira Garza-González, Soraya Mendoza-Olazarán, Rayo Morfin-Otero, Andrea Ramírez-Fontes, Patricia Rodríguez-Zulueta, Samantha Flores-Treviño, Paola Bocanegra-Ibarias, Héctor Maldonado-Garza, Adrián Camacho-Ortiz

“…We included 21 patients (13 in the FMT group and 8 in the FMT-L group). Overall, both groups had a reduction in bowel movements per day, from 8.6 to 3.2 in the first 48 h (62.7% reduction, p=0.001). …”
Get full text

Fatigue, pain and faecal incontinence in adult inflammatory bowel disease patients and the unmet need: a national cross-sectional survey by Ailsa Hart, Laura Miller, Fionn Cléirigh Büttner, Thomas Hamborg, Sonia Saxena, Richard C. G. Pollok, Imogen Stagg, Vari Wileman, Qasim Aziz, Wladyslawa Czuber-Dochan, Lesley Dibley, Borislava Mihaylova, Rona Moss-Morris, Chris Roukas, Christine Norton

“…Fatigue and pain were moderately correlated (Pearson correlation coefficient 0.57); both fatigue and pain had a lower correlation with faecal incontinence (0.43 and 0.46 respectively). …”
Get full text

Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

“…This includes the verification of different critical components like the newly developed CFRP pressure vessel containing the primary payload and the Micrometeoroid and Debris Protection Shield, which protects it. Both items went through rigorous testing, including high-velocity impact tests, to ensure their reliability in orbit. …”
Get full text

When specific exercise is more effective than medication - Sensorimotor training is currently the most promising option to treat and prevent chemotherapy-induced peripheral neuropa... by Fiona Streckmann, Maryam Balke, Céline Hammadou, Bianca Schmidli, Oliver Faude, Sarah Koch

“…The incidence of CIPN in participants was significantly lower in both intervention groups compared to the control group (TAU): (SMT, 12 of 40 [30.0%; 95% CI, 17.9%-42.1%] and WBV, 14 of 34 [41.2%; 95% CI, 27.9%-54.5%] vs TAU, 24 of 34 [70.6%; 95% CI, 58.0%-83.2%]; P = .002 for intention to treat–MH). …”
Get full text

Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis by Lisanne B. M. Bakker, Claudine J. C. Lamoth, Tomas Vetrovsky, Markus Gruber, Simone R. Caljouw, Ward Nieboer, Wolfgang Taube, Jaap H. van Dieën, Urs Granacher, Tibor Hortobágyi

“…The overall analysis revealed that acute and chronic balance training had a large effect on the neural correlates of balance skill learning in the two age groups combined (g = 0.79, p < 0.01). Both age groups similarly improved balance skill performance in 1–3 training sessions and showed little further improvements with additional sessions. …”
Get full text