Integration and Comparative Analysis of Remote Sensing and In Situ Observations of Aerosol Optical Characteristics Beneath Clouds by Jing Chen, Jing Duan, Ling Yang, Yong Chen, Lijun Guo, Juan Cai

“…The validation results show that at the comparison heights, under cloudy-sky conditions with strong winds (>3.4 m/s) and high relative humidity (RH) (>70%), the aerosol extinction coefficients between the two sites are in good agreement; thus, the observations at the top of the mountain are more suitable for in situ validation under cloudy-sky conditions; however, the local circulations under clear-sky conditions lead to large differences in the aerosol properties at the same altitude between the two sites and are unsuitable for validation. …”
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Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmona... by Huang SY, Hsieh PC, Huang KL, Yang MC, Jao LY, Tzeng IS, Lan CC, Wu YK

“…George’s Respiratory Questionnaire (SGRQ).Results: PR significantly improved exercise capacity (peak work rate and oxygen consumption), dyspnea score, and all domains of the SGRQ, maximum expiratory pressure, ventilatory equivalent, respiratory rate, and mean blood pressure at rest in both groups (p < 0.05). However, improvements in O2P, maximal inspiratory pressure, and tidal volume at rest were observed only in Group 2 but not in Group 1.Conclusion: PR improves exercise capacity, HRQL and specific respiratory function in participants with COPD, regardless of baseline O2P levels. …”
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Provide a Framework for the Application of Open Policy Making in Parliament of Iran by Mohsen Eynali, Seyed Abbas Ebrahimi, Mohsen Farhadinejad, Hasan Danaeefard

“…They include achieving more optimal policy adoption through collaborative efforts, garnering robust stakeholder support for the implementation of desired policies, enhancing access to critical data for both elites and the general public, significantly increasing public participation in the policy-making process, and substantially boosting public trust in governing institutions, such as the Shura Council. …”
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Association between Chronic Pain and Diabetes/Prediabetes: A Population-Based Cross-Sectional Survey in Saudi Arabia by Khaled K. Aldossari, Mamdouh M. Shubair, Jamaan Al-Zahrani, Abdulrahman A. Alduraywish, Khalid AlAhmary, Salwa Bahkali, Sara M. Aloudah, Sami Almustanyir, Laila Al-Rizqi, Sally A. El-Zahaby, Paivi Toivola, Ashraf El-Metwally

“…A population-based cross-sectional questionnaire survey study was conducted in Al-Kharj, Saudi Arabia, from January 2016 to June 2016. Participants from both private and governmental institutions were selected following a multistage sampling technique and using a cluster sampling method. …”
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Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2 by Charlotte Laurfelt Munch Rasmussen, Signe Frost Frederiksen, Christian Würtz Heegaard, Maj Schneider Thomsen, Eva Hede, Bartosz Laczek, Jakob Körbelin, Daniel Wüstner, Louiza Bohn Thomsen, Markus Schwaninger, Ole N. Jensen, Torben Moos, Annette Burkhart

“…Abstract Background Patients with the genetic disorder Niemann-Pick type C2 disease (NP-C2) suffer from lysosomal accumulation of cholesterol causing both systemic and severe neurological symptoms. In a murine NP-C2 model, otherwise successful intravenous Niemann-Pick C2 protein (NPC2) replacement therapy fails to alleviate progressive neurodegeneration as infused NPC2 cannot cross the blood–brain barrier (BBB). …”
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Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma by Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu

“…Furthermore, our results revealed the correlation between APP and the transcription factor TRPS1. Both APP and TRPS1 demonstrated significant effects on cancer cell proliferation, migration, and invasion, potentially contributing to tumor progression. …”
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Human neural rosettes secrete bioactive extracellular vesicles enriched in neuronal and glial cellular components by Malena Herrera Lopez, Matías Bertone Arolfo, Mónica Remedi, Laura Gastaldi, Carlos Wilson, Gonzalo G. Guendulain, Danilo Ceschin, Andrés Cardozo Gizzi, Alfredo Cáceres, Ana Lis Moyano

“…This transcription factor modulates both neural differentiation and pluripotency. Interestingly, these effects were inhibited by antibodies against an unexpected neuroglial cargo of hNR-EVs: the major proteolipid protein (PLP). …”
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Characteristics of Hydrogels as a Coating for Microneedle Transdermal Delivery Systems with Agomelatine by Monika Wojtyłko, Ariadna B. Nowicka, Anna Froelich, Mirosław Szybowicz, Tobiasz Banaszek, Dorota Tomczak, Wiesław Kuczko, Radosław Wichniarek, Irena Budnik, Barbara Jadach, Oliwia Kordyl, Antoni Białek, Julia Krysztofiak, Tomasz Osmałek, Dimitrios A. Lamprou

“…The optimized formulations were subjected to spectroscopic and rheological characterization and mechanical tests, as well as tested for release through an artificial membrane and permeation through human skin ex vivo. Both hydrogels were found to have suitable parameters for coating microneedles using the dip-coating method, including the stability of the substance at the process temperature, shear-thinning behavior, and appropriate textural parameters such as adhesion or hardness. …”
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Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study by Kim Dunleavy, Heidi Liss Radunovich, Jason M Beneciuk, Boyi Hu, Yang Yang, Janeen McCormick Blythe, Kelly K Gurka

“…Trial RegistrationClinicalTrials.gov NCT06153199; http://clinicaltrials.gov/study/NCT06153199 International Registered Report Identifier (IRRID)DERR1-10.2196/64817…”
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Approach to death and dying patients and its relation with death anxiety among medical interns: a multicenter cross-sectional study by Israa Sharabati, Mohamed M. M. Mustafa, Masah Ateeq, Hasan Al-jabali, Amira Ahmed Elsayed, Ahmed Hamdy Kandil, Mohamed Nabil Hamouda, Noor Alrawajfeh, Sadeel Abu Sharib, Razan A. Abumayyala, Omar Rafeek Alkhateeb, Mira Bishtawi, Juana Abu Rahmeh, Tasneem Hetta, Raghad Abuzant, Farah Al-Mubaid

“…Simple linear regression showed that the DAS significantly predicts both subscales. Conclusions Medical interns showed moderate death anxiety and a positive attitude toward communication and avoidance of death and dying patients. …”
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The Potency of Essential Oils in Combating Stored-Product Pests: From Nature to Nemesis by Nickolas G. Kavallieratos, Nikoleta Eleftheriadou, Constantin S. Filintas, Maria C. Boukouvala, Demeter Lorentha S. Gidari, Anna Skourti, Dionysios Ntinokas, Marta Ferrati, Eleonora Spinozzi, Riccardo Petrelli, Filippo Maggi

“…On the contrary, <i>M. myristica</i> and <i>X. aethiopica</i> EOs showed less overall efficacy despite their potency against some pests. Both <i>I. verum</i> and <i>C. reticulata</i> EOs outperformed the positive control, pirimiphos-methyl, in several assays. …”
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Exploring the Impact of Citric Acid on Mitigating Sweet Potato Soft Rot and Enhancing Postharvest Quality by Yixi Chen, Linjiang Pang, Jiacheng Bai, Wenbao Yu, Yueming Zhu, Melvin Sidikie George, Zunfu Lv, Guoquan Lu

“…The main theme of this study is to determine the CAC inhibitory mechanism against <i>Rhizopus stolonifer</i>, the causative agent of sweet potato soft rot. To ascertain the practical applicability of CAC, both in vitro and in vivo methodologies were employed. …”
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Factors associated with thermal injury of abdominal skin in focused ultrasound ablation of uterine fibroids by Tang Chendian, Huang Guohua, Zhibiao Wang, Liu Fang, Shuang Luo, Xiaofang Liu, Qiuling Shi

“…And as the level of thermal injury rose, the ratio gradually increased, however, without statistical difference.Conclusions Based on our limited results, the following conclusion was made. (1) Abdominal scars, abdominal wall thickness, fundus fibroids, UFs with T2WI hyperintense/mixed signals, AP and TT were independent risk factor. (2) Neither too thick nor too thin abdominal walls would be recommended, as both might increase the risk of skin injury. (3) Noticeably, the risk of skin injury might increase considerably when the ST was longer and the sonication area was more fixed.…”
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Control strategy for the core power in an accelerator drive sub-critical system by Xinxin Li, Yuan He, Wenjing Ma, Wenjuan Cui, Zhiyong He, Detai Zhou, Hai Zheng, Feng Yang, Yuhui Guo, Haihua Niu, Kai Yin, Shiwu Dang

“…Firstly, the beam power is set roughly by assigning a new duty factor, where the duty factor is set by changing the beam macro-pulse length and the pulse repetition rate of the proton beam. Both the pulse length and the repetition rate are assigned by a timing system. …”
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ADAPTIVE COMFORT PADA GRAND STUDIO PROGRAM STUDI ARSITEKTUR FAKULTAS TEKNIK UNIVERSITAS MALIKUSSALEH by Atthaillah Atthaillah, Eri Saputra, Muhammad Iqbal

“…The thermal sensation of the space was uncomfortable both for students and lecturers who had used the studio.  …”
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Hypercalcemia Following Adrenalectomy for Cushing Syndrome in a Patient with Post-Surgical Hypoparathyroidism by Pietro Locantore, Alessandro Oliva, Gianluca Cera, Rosa Maria Paragliola, Roberto Novizio, Caterina Policola, Andrea Corsello, Alfredo Pontecorvi

“…Common and rare causes of hypercalcemia were excluded, and the persistence of severely elevated calcium levels led to the empirical use of intravenous clodronate, achieving remission of both hypercalcemia and, unexpectedly, hypoparathyroidism. …”
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eHealth literacy in the general population: a cross-sectional study in China by Chao Sun, Eline Meijer, Niels H. Chavannes, Huohuo Dai, Xiao Li, Yue Wang, Liangqiuhe Wu, Qing Zhang, Marise J. Kasteleyn

“…Younger age, higher educational and income level, having digital access, more frequent eHealth use and more positive attitudes towards eHealth were significantly associated with higher eHL. Efforts at both individual and systematic levels should be made to improve eHL, and promote CLD knowledge and digital access, especially in disadvantaged populations. …”
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Mapping QTL for Root and Shoot Morphological Traits in a Durum Wheat × T. dicoccum Segregating Population at Seedling Stage by Anna Iannucci, Daniela Marone, Maria Anna Russo, Pasquale De Vita, Vito Miullo, Pina Ferragonio, Antonio Blanco, Agata Gadaleta, Anna Maria Mastrangelo

“…Three QTL were mapped to chromosome 4B, one of which corresponds to the Rht-B1 locus and has a large impact on both shoot and root traits (LOD 21.6). Other QTL that have specific effects on root morphological traits were also identified. …”
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Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes by Ali Tawbeh, Catherine Gondcaille, Fatima-Ezzahra Saih, Quentin Raas, Damien Loichot, Yannick Hamon, Céline Keime, Alexandre Benani, Francesca Di Cara, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

“…Exposure to CM from LPS-stimulated mutant microglial cells significantly increased apoptosis in both cell types. Furthermore, treated neurons exhibited a reduction in cell complexity and an increased ability to secrete neuropeptides. …”
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DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer by T. E. Buffart, J. Coffa, M. A. J. A. Hermsen, B. Carvalho, J. R. M. van der Sijp, B. Ylstra, G. Pals, J. P. Schouten, G. A. Meijer

“…Background: C-Myc, a well-known oncogene located on 8q24.12–q24.23, is often amplified and over-expressed in both primary and metastasizing colorectal cancer. …”
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