Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions by Martin Škandík, Lara Friess, Guillermo Vázquez-Cabrera, Lily Keane, Kathleen Grabert, Mireia Cruz De los Santos, Mercedes Posada-Pérez, Austeja Baleviciute, Mathilde Cheray, Bertrand Joseph

“…Additionally, four other genes—CAPG, LGALS3BP, NRIP1, and P2RY12—were found to share regulatory patterns in response to both aging and extrinsic activation. An in-depth investigation focused on SLC16A3, encoding the high-affinity lactate transporter MCT4, revealed disruptions in extracellular acidification rate and lactate concentration with age. …”
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一种降低南极磷虾油酸值的工艺研究 Technology of reducing acid value of Antarctic krill oil by 胥亚夫，俞存兵，余奕珂，郭忠，吴微，吕晶，郝兰 " XU Yafu, YU Cunbing, YU Yike, GUO Zhong, WU Wei, LYU Jing，HAO Lan"

“…Under the optimal conditions, the yield of deacidfied Antarctic krill oil reached 92.5%, the acid value was reduced from 11.53 mgKOH/g to 5.74 mgKOH/g, the phospholipid content decreased from 53.36% to 52.33%, and both fluidity and transparency were improved. In conclusion, the magnesium silicate deacidification process can effectively reduce the acid value while retain its nutritional component phospholipid in Antarctic krill oil. …”
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Health and economic cost estimates of short-term total and wildfire PM2.5 exposure on work loss: using the consecutive California Health Interview Survey (CHIS) data 2015–2018 by Michael Jerrett, Yu Yu, Ying-Ying Meng, Diane Garcia-Gonzales, Mohammad Z Al-Hamdan, Miriam E Marlier, Joseph L Wilkins, Ninez Ponce

“…Using the function coefficient in the current BenMAP, the excess work-loss days due to sickness was about 250 000 days and the estimated economic loss was about $45–50 million for each 1 µg/m3 increase in daily total PM2.5 exposure, and wildfire smoke alone would lead to 0.17–0.67 million work-loss days with related economic loss of $31–128 million per year during the same period.Conclusions Both conventional and wildfire-specific sources of PM2.5 produced substantial work loss and cost in California. …”
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New dimension in vortex electro-magnetic wave transmission with orbital angular momentum by Chao ZHANG, Yuanhe WANG

“…Conclusion:In response to the controversy on whether OAM electromagnetic waves can provide the new dimension for the wireless transmission, this paper analyzes the physical insight of the EM wave transmission with OAM in history.It can be concluded that:both the intrinsic OAM and the extrinsic OAM can be utilized by EM waves,but only quantum OAM vortex microwave photons transmission based on intrinsic OAM can generate new dimensions in the wireless transmission besides the MIMO transmission. …”
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Aging-enhanced autophagy activity promotes fibrotic progression via the TGF-β2/Smad signaling pathway in trabecular meshwork cells—a new insight from POAG by Jin Han, Jun Wang, Ling Shen, Yiting Cai, Xuze Wang, Ailixiati Wumaier, Wei Chen, Wei Han

“…In the H2O2-induced aging model, TM cells displayed both elevated autophagic activity and fibrosis. Further investigation showed that enhanced autophagy activity promoted fibrotic progression via activation of the TGF-β2/Smad signaling pathway. …”
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Spartina alterniflora invasion significantly alters the assembly and structure of soil bacterial communities in the Yellow River Delta by Pengyuan Sun, Yuxin Wu, Pengcheng Zhu, Jingfeng Wang, Jingfeng Wang, Xiaona Yu, Weihua Guo

“…In comparison, S. alterniflora-associated bacterial communities were enriched with both sulfate-reducing bacteria (SEEP-SRB1) and sulfate-oxidizing bacteria (Sulfurimonas), which maintained a dynamic balance in the local sulfur-cycle, and thereby enhanced S. alterniflora growth. …”
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Predicting ixodid tick distribution in Tamil Nadu domestic mammals using ensemble species distribution models by Ayyanar Elango, Hari Kishan Raju, Ananganallur Nagarajan Shriram, Ashwani Kumar, Manju Rahi

“…Conclusions Our results suggest that MaxEnt is a suitable model for predicting the distribution of tick species. Both environmental factors such as LULC, elevation and soil type and bioclimatic factors such as temperature and precipitation contribute significantly to predicting tick species distribution in domestic animals in Tamil Nadu. …”
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Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy by Yun Qin, Yanan Li, Bo Sun, Hui He, Rui Peng, Tao Zhang, Jianfu Li, Cheng Luo, Chengyan Sun, Dezhong Yao

“…Furthermore, the disconnections of the FNC consistently focused on the visual pathway; covariance of the default mode network (DMN) with other networks was observed both in DCP and SCP groups, while the DCP group had a distinct connectivity abnormality in motor pathway and self-referential processing-related connections. …”
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Interaction between 24 h Urinary Free Cortisol and Obesity in Hypertension-Mediated Organ Damage in Patients with Untreated Hypertension by Gao-Zhen Cao, Jia-Yi Huang, Qing-Shan Lin, Cong Chen, Min Wu, Run Wang, Ming-Yen Ng, Kai-Hang Yiu, Jian-Cheng Xiu

“…Additionally, obesity modified the effects of 24 h UFC on both LVH and albuminuria.…”
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Une gestion plurielle des illégalismes : négociations et contradictions dans la régulation des eaux usées au Maroc by Pierre-Louis Mayaux, Naïma Fezza, Zhour Bouzidi

“…Rather, frustrations abound on both sides. Many State actors would like to see much stronger sanctions, while the moqqadems are constantly exposed to contradictory pressures, including calls for coercion, farmers' capacity to resist and adapt, and the recognition of their moral right to subsistence. …”
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Novel MRI Signs in Atlantodental Space Predict Reduction Degree of Atlantoaxial Dislocation by Xia‐Qing Sheng, Yi‐Fei Deng, Cheng‐Yi Huang, Nan‐Fang Pan, You‐Jin Zhao, Qi‐Yong Gong, Quan Gong, Yue‐Ming Song, Hao Liu, Yang Meng

“…The intra‐observer consistency for MRI signs was also better than that of dynamic digital radiography. Both the flexible tissue sign and radiographically reducible groups showed a higher rate of satisfactory reduction. …”
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Clinicopathological and molecular characteristics of papillary thyroid carcinoma in adolescent and young adult patients by Van Phu Thang Nguyen, Hirokazu Kurohama, Yuko Akazawa, Thi Ngoc Anh Nguyen, Katsuya Matsuda, Yuki Matsuoka, Zhanna Mussazhanova, Kenichi Yokota, Shinya Satoh, Hiroyuki Yamashita, Thi Nhung Nguyen, Yerkerzhan Sailaubekova, Masahiro Nakashima

“…The prevalences of BRAF p.V600E and TERT promoter mutations of PTC were significantly lower in AYA patients (69.1% vs. 82.6% and 1.3% vs. 18.8%, respectively; both p < 0.001). In conclusion, PTC in AYA patients differed from PTC in older patients. …”
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Testicular biometrics of Murrah buffaloes in different age groups by Erly L. Carrascal-Triana, Jorge Mejía Lúquez, Divier Agudelo Gómez, Edison Julián Ramírez Toro

“…The TV was determined using the equation of the spheroid prolate and represented the average of both testes. Descriptive statistics were performed for each variable; for the SC and TV, a linear regression model as a function of age and weight was analyzed, and simple Pearson correlations were performed. …”
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Relationship between Particulate Matter (PM10) and Airway Inflammation Measured with Exhaled Nitric Oxide Test in Seoul, Korea by Juwhan Choi, Jae Kyeom Sim, Jee Youn Oh, Young Seok Lee, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim, Ji-yong Moon, Kyung Hoon Min

“…The positive correlation was found in both healthy people and asthmatic patients. Therefore, PM10 can increase airway inflammation.…”
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Impaired pulmonary function increases the risk of gout: evidence from a large cohort study in the UK Biobank by Zijian Kang, Jianzheng Zhang, Chen Zhu, Ying Zhu, Hanlei Jiang, Qiang Tong, Sheng-Ming Dai

Subjects: “…Gout…”
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Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1 by Jessica Purizaca, Adriana Contreras-Quiroz, Elisa Dorantes-Acosta, Eduardo Vadillo, Lourdes Arriaga-Pizano, Silvestre Fuentes-Figueroa, Horacio Villagomez-Barragán, Patricia Flores-Guzmán, Antonio Alvarado-Moreno, Hector Mayani, Isaura Meza, Rosaura Hernandez, Sara Huerta-Yepez, Rosana Pelayo

“…Substantial progress on understanding the cell hierarchy within ALL bone marrow (BM) has been recorded in the last few years, suggesting that both primitive cell fractions and committed lymphoid blasts with immature stem cell-like properties contain leukemia-initiating cells. …”
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Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates by Zoe M. Wright, Kevin John Butay, Juno M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose, Israa S. Hissein, Jason G. Williams, Mario J. Borgnia, Meredith N. Frazier, Geoffrey A. Mueller, Robin E. Stanley

“…We address this gap by designing fluorinated double stranded RNA substrates that allow us to directly relate a U’s sequence context to both its tendency to spontaneously flip and its susceptibility to cleavage by Nsp15. …”
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Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS by Wenxiu Chen, Jianliang Miao, Jingfei Chen, Jianlin Chen

“…Hub genes were selected by intersecting the results of both methods after using LASSO and SVM-RFE for central gene selection for DEGs. …”
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Identification of the Insecticidal Effect of Cry Protein on a Variety of Potato Pests by Deshan ZHOU, Doudou YANG, Juan LIU, Weichao LIN, Jie CHENG, Suhua LI

“…The Cry proteins (Cry1B, Cry1Ac, Cry3A, Cry3B) was applied by using both feed addition and leaf coating methods, and sterile water (CK) and different concentrations of Cry protein treatment groups were set up. …”
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Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or second... by Jiaying Wu, Wanying Liu, Yang Cao, Yang Yang, Zhen Shang, Mi Zhou, Yicheng Zhang, Fankai Meng, Xiaojian Zhu, Yi Xiao

“…The incidence rates of severe cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome were both 13.2%. Among the 25 patients with secondary CNSL (SCNSL), the best ORRs were 91.7% for those with CNS lesions only and 61.5% for those with CNS and systemic lesions (P = 0.160), while the estimated 1-year PFS rates were 83.3% and 38.5%, respectively (P = 0.030). …”
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