Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons by Jones, Auriane G., Schaal, Gauthier, Boyé, Aurélien, Creemers, Marie, Derolez, Valérie, Desroy, Nicolas, Fiandrino, Annie, Mouton, Théophile L., Simier, Monique, Smith, Niamh, Ouisse, Vincent

“…Furthermore, M-AMBI, a multivariate index composed of species richness, Shannon diversity and AMBI (AZTI's Marine Biotic Index) and currently used to evaluate the ecological state of French coastal lagoons, was more sensitive to eutrophication (18%) than to natural variability (9%), with nonetheless 49% of its variability explained jointly by both. To improve the robustness of benthic indicators like M-AMBI and increase the effectiveness of lagoon benthic habitat management, we call for a revision of the ecological groups at the base of the AMBI index and of the current lagoon typology which could be inspired by the lagoon-sea connection levels used in this study.…”
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Cost of introducing and delivering malaria vaccine (RTS,S/AS01E) in areas of seasonal malaria transmission, Mali and Burkina Faso by Jean Bosco Ouédraogo, Alassane Dicko, Ranju Baral, Clint Pecenka, Halimatou Diawara, Fadima Yaya Bocoum, Ann Levin, Cynthia Lee, Fatoumata Koita, Rosemonde Guissou, Seydou Yabré, Seydou Traoré, Winthrop Morgan

“…Service delivery accounts for 2%–8% and 12%–23% of the total financial cost under routine EPI and mixed delivery scenarios, respectively.Conclusion Vaccine delivery using the mass campaign approach is most costly followed by mixed delivery and routine EPI delivery approaches, in both countries. Our cost estimates provide useful insights for decisions regarding delivery approaches, as countries plan the malaria vaccine rollout.…”
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Demographic and Clinical Characteristics of Patients with Corneal Ectasia at Multiple Medical Centers in Saudi Arabia: A Hospital-based Study by Waleed Alghamdi, Sulaiman Aldakhil, Saif Hassan Alrasheed, Kareem Allinjawi, Mustafa Abdu, Raghda F. Mutwaly, Khaled Al Rashah, Hani M. Ghazal, Ghassan H. Radwan, Naveen Kumar Challa

“…This high rate of bilaterality of diseases during diagnosis may be due to misdiagnosis in the initial stages, which highlights the importance of community and eye care professionals’ awareness of comprehensive eye examinations and regular follow-up, including corneal topography assessments of both eyes.…”
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Remote Continuous Microinjury-Triggered Cytokines Facilitate Severe Diabetic Foot Ulcer Healing via the Ras/Raf/MEK/ERK Pathway by Huang X, Liu J, Wu X, Mo Y, Luo X, Yang Y, Yang C, Liang X, Liang R, Chen Y, Fan Z, Lu W, Chen Y, Hua Q

“…These changes were in parallel with the expression of TGF-β 1, PDGF-BB, and VEGF in the foot wounds and the frequency of EPCs in both bone marrow and peripheral circulation, which implied that the secreted TGF-β 1, PDGF-BB, and VEGF promote proliferation and migration of EPCs to the foot wounds. …”
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Agronomic Performance of European Pear Cultivars in Different Training Systems in the Highland Region of Southern Brazil by Alex Felix Dias, Sabrina Baldissera, Alberto Ramos Luz, Augusto Schütz Ferreira, Bruno Dalazen Machado, Bruno Pirolli, Renaldo Borges de Andrade Júnior, Joel de Castro Ribeiro, Daiana Petry Rufato, Aike Anneliese Kretzschmar, Amauri Bogo, Leo Rufato

“…The evaluation was conducted over the 2016/2017 to 2022/2023 growing seasons in the highland region of southern Brazil. Both Tall Spindle systems significantly improved the yield and productive efficiency compared to the Bi-axis system, with ‘Santa Maria’ showing superior performance under Tall Spindle—90°. …”
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Evaluation of longan (Dimocarpus longan) peel powder as fruit by-product additive in Nile tilapia (Oreochromis niloticus) feed: Effects on growth, immunity, and immune-antioxidant... by Supreya Wannavijit, Piyatida Outama, Chinh Le Xuan, Camilla Maria Fontana, Marina Paolucci, Md Afsar Ahmed Sumon, Ehab El-Haroun, Hien Van Doan

“…Moreover, skin mucus and serum immune parameters (lysozyme and peroxidase activity) were significantly higher (P < 0.05) in fish fed with different LP concentrations at both 4 and 8 weeks. Similarly, analysis of mRNA transcripts of immune (IL-1, IL-8, and LBP) and antioxidant (GSTa, GPX, and GSR) gene expressions showed a significant upregulation (P < 0.05) in LP-fed diet groups compared to the control group. …”
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Identification of TMPRSS3 as a Significant Contributor to Autosomal Recessive Hearing Loss in the Chinese Population by Xue Gao, Sha-Sha Huang, Yong-Yi Yuan, Jin-Cao Xu, Ping Gu, Dan Bai, Dong-Yang Kang, Ming-Yu Han, Guo-Jian Wang, Mei-Guang Zhang, Jia Li, Pu Dai

“…Each of the five novel mutations was classified as severe, by both age of onset and severity of hearing loss. Together with our previous study, six families were found to share one pathogenic mutation (c.916G>A, p.Ala306Thr). …”
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Seroprevalence of Foot and Mouth Disease Virus Infection in Some Wildlife and Cattle in Bauchi State, Nigeria by Y. J. Atuman, C. A. Kudi, P. A. Abdu, O. O. Okubanjo, A. Abubakar, Y. Wungak, H. G. Ularamu

“…Foot and mouth disease (FMD) is an important transboundary viral disease of both domestic and wild cloven-hoofed animals characterized by high morbidity with devastating consequence on the livestock worldwide. …”
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Metagenomic next-generation sequencing for the clinical identification of spinal infection-associated pathogens by Tengfei Shi, Yuhan Lin, Xuexin Zheng, Hongliang Ruan, Rui Zhang, Yinhuan Liu, Shaohan Xu, Shaohan Xu, Huafeng Wang

“…For the 40 cases with positive results for both culture- and mNGS-based identification, high consistency (77.50%) was observed. …”
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Patterns of interpopulation variation and physiological trade-offs of the acute thermal tolerance of juvenile Chinook salmon (Oncorhynchus tshawytscha) by Kenneth W. Zillig, Kenneth W. Zillig, Heather N. Bell, Alyssa M. FitzGerald, Alyssa M. FitzGerald, Nann A. Fangue

“…Trade-offs were analyzed at both individual and population scales. Associations between ΔCTM, acclimation capacity, and source population environmental characteristics were also examined using data from a landscape-scale, regional, river temperature model.ResultsFish acclimated to 16°C or 20°C exhibited heat hardening (positive ΔCTM), while those acclimated to 11°C exhibited “heat weakening” (negative ΔCTM), a rare phenomenon in the literature. …”
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Tumoral Prostate Shows Different Expression Pattern of Somatostatin Receptor 2 (SSTR2) and Phosphotyrosine Phosphatase SHP-1 (PTPN6) According to Tumor Progression by Ariel Ernesto Cariaga-Martinez, María Angelica Lorenzati, Mario Alejandro Riera, Marisa Angelica Cubilla, Andrés De La Rossa, Ernesto Martín Giorgio, María Mercedes Tiscornia, Esteban Mariano Gimenez, María Eugenia Rojas, Bárbara Julieta Chaneton, Dora Isabel Rodríguez, Pedro Darío Zapata

“…Our studies have shown that epithelial expressions of both proteins, SHP-1 and SSTR2, in normal and benign hyperplasia are localized in the luminal side of duct and acinar cells. …”
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Modulation of Acupuncture at Quchi (LI 11) and Waiguan (SJ 5) acupoints on LTP-like Plasticity by Qianqian SUN, Guo YU, Huitian ZHANG, Xiaokuo HE

“…The MEP amplitudes used bilaterally were increased MEP amplitudes after the needle removal (<italic>P</italic>&lt;0.01).②After induced by PAS, significant changes were found both contralateral and ipsilateral acupuncture sizes compared to baseline (<italic>P</italic>&lt;0.01). …”
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Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug by Abla KK, Alamoudi MK, Soliman GA, Abdel-Kader MS, Aldawsari MF, Mehanna MM

“…Kawthar K Abla,1 Mariam K Alamoudi,2 Gamal A Soliman,2,3 Maged S Abdel-Kader,4,5 Mohammed F Aldawsari,6 Mohammed M Mehanna7,8 1Department of Pharmaceutical Science, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon; 2Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 3Department of Pharmacology, College of Veterinary Medicine, Cairo University, Giza, Egypt; 4Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 5Department of Pharmacognosy, College of Pharmacy, Alexandria University, Alexandria, Egypt; 6Department Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia; 7Department of Pharmaceutical Sciences, School of Pharmacy, Lebanese American University, Byblos, Lebanon; 8Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptCorrespondence: Mohammed M Mehanna, Department of Industrial Pharmacy, Alexandria University, Alexandria, Egypt, Email mohamed.mehanna@alexu.edu.egIntroduction: Androgenetic alopecia (AGA) is a multifactorial and age-related dermatological disease that affects both males and females, usually at older ages. Traditional hair repair drugs exemplified by minoxidil have limitations such as skin irritation and hypertrichosis. …”
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Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination sur... by Lihua Huang, Liuliu He, Qingfeng Zeng, Jinjing Huang, Xiaoyan Luo, Qiuming Zhong

“…Higher risks of all-cause mortality were noted in the lowest and highest HbA1c quartiles, with adjusted HR (95% CI) of 1.48 (1.18–1.87) and 1.31 (1.01–1.70) respectively. …”
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Innovations in bioethanol production: A comprehensive review of feedstock generations and technology advances by Abeer Kazmi, Tahira Sultana, Amir Ali, Aneela Nijabat, Gaojie Li, Hongwei Hou

“…The production of bioethanol from food waste might result in a long-lasting method that would satisfy both the growing population's energy needs and the problem of disposing of food waste. …”
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Optimising Growth, Immunity, and Gene Expression in Broiler Chickens Through Dietary Threonine Levels and Oil Inclusion by Mohamed I. El‐Katcha, Mosaad A. Soltan, Heba I. Ghamry, Abeer F. El‐Nahas, Laila A. Al‐Shuraym, Ostan Mihaela, Rada Olga, Rasha E. Azab, Ahmed Abdeen, Mustafa Shukry, Set A. El‐Shobokshy

“…ABSTRACT Background The inclusion of synthetic amino acids in poultry nutrition plays a crucial role in both enhancing the synthesis of immunoglobulins and elevating the overall comprehensiveness of the amino acid profile. …”
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A Localized Model for Branding in the Iranian Dairy Industry by Shaghayegh Sabaghi, Alireza Rousta, Farzad Asayesh

“…ConclusionBased on the findings of this research, adopting a comprehensive branding model in dairy companies has the potential to enhance both market and financial performance.…”
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Flavonoids and anthocyanins in seagrasses: implications for climate change adaptation and resilience by Jana Botes, Jana Botes, Xiao Ma, Xiao Ma, Jiyang Chang, Jiyang Chang, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Dave Kenneth Berger, Dave Kenneth Berger

“…The phenomenon of reddening in certain seagrass species typically focuses on the importance of anthocyanins as a UV-screening mechanism, while the role of anthocyanins in cold stress is discussed less often. Both of these stress response functions would be useful for adaptation to climate change-induced deviations in tidal patterns and emersion. …”
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Effect of ethnicity and other sociodemographic factors on attendance at ophthalmology appointments following referral from a Diabetic Eye Screening Programme: a retrospective cohor... by James Banks, Adnan Tufail, Ling Zhi Heng, Josef Huemer, Christopher G Owen, Alicja R Rudnicka, Yasir Khan, Abraham Olvera-Barrios, Michael Seltene, Mumina Khatun, Catherine A Egan, Zoe Ockrim, Matilda Pitt, Daisy Williams, Celestine Rutowska

“…Those with higher levels of deprivation, younger (aged 18–45 years) and older (76–90 years) age groups and worse visual acuity were less likely to attend, whereas people identified as having proliferative DR in both eyes were more likely to attend.Conclusion Sociodemographic patterns in attendance after referral from the DESP to the HES exist, and these do not appear to explain ethnic differences in more severe sight-threatening DR, suggesting other explanations. …”
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Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head by Peng Zhang, Qing-He Ye, Wen-Xiu Zhu, Yong-Heng Zhao, Hong-Xun Zhu, Biao-Fang Wei

“…The levels of CHOP and GRP78, both in serum and at the local site, were in a positive correlation with VAS scores but an inverse relationship with HHS. …”
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