A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…HbA1c decreased from baseline to EOS in both V-Go (-1.0%, p<.001) and STO (-0.5%, p<.001); V-Go had significantly larger decrease (p=.002). …”
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A novel technique of blindly positioning bronchial blockers for one-lung ventilation: a prospective, randomized, crossover study by Seihee Min, Susie Yoon, Jiwon Han, Jeong-Hwa Seo, Jae-Hyon Bahk

“…Trial registration This study was registered in ClinicalTrials.gov (NCT02981537) on December 05, 2016.…”
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Spatial mapping of the localized corrosion behavior of a magnesium alloy AZ31B tungsten inert gas weld by Leslie G. (Bland) Miller, Corey M. Efaw, Rebecca F. Schaller, Kari Higginbotham, Steve D. Johns, Paul H. Davis, Elton Graugnard, John R. Scully, Michael F. Hurley

“…Insight into the changing nature of the galvanic couples between weld zones and at localized microgalvanic sites were investigated using SECM and SKPFM to map both electrochemically active regions and Volta potential differences across the weld-affected zones. …”
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Breast Cancer Conditioned Media Modulate the Expression of Immune Checkpoints and Adhesion Molecules in Endothelial Cells by İpek Türkdönmez, Emel Şahin, Mehmet Şahin

“…Results: CRL-2329-CM was found to increase cell proliferation at the end of 48 h but not 24 h, compared to the control (CRL-4010-CM) group (p=0.0052). In addition, both cancer cell-CMs were revealed to induce migration (p&lt;0.001). …”
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Waist circumference and altered metabolic indices are associated with increased resting pulse rate in middle-aged adults by Laith Ashour, Zaid Taimeh, Moaiad Hussein, Zeid Jarrar, Nicola Hanna Madani, Noor Mnaa, Layan Ayesh, Ahmad Odeh, Sama Samer Abu Monshar, Muath Mohammad Dabas, Rawan Almejaibal

“…A significant increase was also observed in individuals with hypertension stage 1 and 2 [p<0.001 for both; coefficients = 2.98 (95% CI: 1.45-4.52) and 7.2 (95% CI: 5.28-9.12), respectively]. …”
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Serum metabolic profiles in quails: Effects of age, breed, and sex by Qin He, Hanle Shang, Yizhong Huang, Lizhi Li, Zhuomin Wu, Huihui Ran, Jiguo Xu, Xinwei Xiong

“…Quails are important models due to their low-cost protein sources—both eggs and meat—and practical benefits such as minimal space requirements, high egg production, disease resistance, and rapid reproduction. …”
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Efficacy and Acceptability of a Mobile App for Monitoring the Clinical Status of Patients With Chronic Obstructive Pulmonary Disease Receiving Home Oxygen Therapy: Randomized Contr... by Anisbed Naranjo-Rojas, Luis Ángel Perula-de Torres, Freiser Eccehomo Cruz-Mosquera, Guillermo Molina-Recio

“…Trial RegistrationClinicalTrials NCT04820790; https://clinicaltrials.gov/study/NCT04820790 International Registered Report Identifier (IRRID)RR2-https://doi.org/10.1186/s12875-021-01450-8…”
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CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy by Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai

“…Notably, αCD7/EVs/CytC/siBcl2 demonstrated similar efficacy against both Molt‐4 and chemotherapy‐resistant Molt‐4 cells (CR‐Molt‐4). …”
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Effects of a novel non-pharmacological intervention based on respiratory biofeedback, neurofeedback and median nerve stimulation to treat children with ADHD by Eduardo Santamaría-Vázquez, Eduardo Santamaría-Vázquez, Eduardo Santamaría-Vázquez, Anayali Estudillo-Guerra, Lna Ali, Diana Martinez, Roberto Hornero, Roberto Hornero, Leon Morales-Quezada

“…The active group received verum MNS, and the sham group received sham MNS. Both groups performed the NFB/R-BFB treatment. Clinical assessments (i.e., Conner's parent rating scale) and electroencephalography (EEG) measurements were taken before the intervention, immediately after treatment, and one month later.ResultsThe results showed that the combined therapy significantly improved behavioral problems, anxiety, hyperactivity, and impulsivity-hyperactivity. …”
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Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway by Yunpeng Lou, Hongguang Shi, Ning Sha, Feifei Li, Xiaofeng Gu, Huiyan Lin

“…Moreover, UDCA inhibited NF-κB p65 phosphorylation and reduced pro-inflammatory cytokines levels (TNF-α, IL-1β, and IL-6) in both serum and kidney. UDCA alleviated oxidative stress by activating the Nrf2/HO-1 pathway in the kidney. …”
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High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation by Dariusz Szukiewicz, Michal Pyzlak, Grzegorz Szewczyk, Aleksandra Stangret, Seweryn Trojanowski, Michal Bachanek, Wojciech Braksator, Jaroslaw Wejman

“…Resveratrol (50 and 100 μM; subgroups B and C) administered into the perfusion fluid lowered the production of both CX3CL1 and TNF-α. The reductions in CX3CL1 levels were more evident in the NG group. …”
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The criteria for choice of myocardial revascularization method in patients with stable coronary artery disease in routine clinical practice by O.A. Yepanchintseva, O.J. Zharinov, K.O. Mikhaliev, A.V. Khokhlov, B.M. Todurov

“…We performed retrospective observational single-center study and analyzed data from the patients with stable CAD (n = 341), suitable for both methods of MR – percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), according to the pre-specified anatomical criteria. …”
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Co–In Bimetallic Hydroxide Nanosheet Arrays With Coexisting Hydroxyl and Metal Vacancies Anchored on Rod‐Like MOF Template for Enhanced Photocatalytic CO2 Reduction by Jingjuan Feng, Weiwei Li, Tianxia Chen, Zhaopeng Zeng, Meng Tian, Wenxin Ji, Yan Guo, Shixiong Min, Xiangyu Liu

“…The metal‐organic framework (MOF) template‐grown LDHs demonstrate excellent promise for exploiting the strengths of both MOFs and LDHs. Herein, the in situ growth of MIL‐68(In)‐NH2 MOF‐templated Co–In bimetallic catalyst (CoIn‐LDH/MOF) having an ultrathin nanosheet morphology on the preserved rod‐like MOF template is demonstrated. …”
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Frequency and Molecular Characteristics of Mismatch Repair-deficient Status among Multiple Synchronous Colorectal Cancers by Kenichi Chikatani, Noriyasu Chika, Noriko Tanabe, Yoshiko Mori, Okihide Suzuki, Takatoshi Matsuyama, Keiichiro Ishibashi, Hidetaka Eguchi, Yasushi Okazaki, Tatsuro Yamaguchi, Hideyuki Ishida

“…The combinations of synchronous tumor sites were the left-sided colon/rectum only (n=67, 50.4%), both the right-sided colon and left-sided colon/rectum (n=42, 31.6%), and the right-sided colon only (n=24, 18.0%). …”
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Combined multi-scale characterization of pores in ultra-thick coal seams of Jurassic Xishanyao Formation, Tiaohu-Malang sags, Santanghu Basin by Yue CHEN, Qiqi LEI, Dongmin MA, Xin WANG, Xinggang WANG, Diefang HUANG, Gaoxiang RONG

“…Micropores contribute the most to the pore specific surface areas for both seams, which are 62.67% and 58.43%, respectively. …”
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Resposta da Vegetação Campos de Altitude às Mudanças Climáticas na Faixa Altitudinal Acima de 400 Metros na Serra do Amolar e Morraria do Urucum, Pantanal Brasileiro by Dhonatan Diego Pessi, Normandes Matos da Silva, Camila Leonardo Mioto, Alfredo Marcelo Grigio, Francisco das Chagas Oliveira, Vinicius de Oliveira Ribeiro, Fábio Veríssimo Gonçalves, Marco Antonio Diodato, Roberto Macedo Gamarra, Felipe Siqueira Pacheco, Antonio Conceição Paranhos Filho

“…This study aims to examine the driving effects of climate change on the spatial distribution of altitude grassland vegetation along an altitudinal range above 400 m in Serra do Amolar and Morraria do Urucum, both inserted in the Pantanal wetlands located in the State of Mato Grosso do Sul, Brazil. …”
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Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization by Annalisa Bosi, Silvia Zanellato, Barbara Bassani, Adriana Albini, Alessandra Musco, Maria Cattoni, Matteo Desio, Elisa Nardecchia, Davide Giuseppe D’Urso, Andrea Imperatori, Lorenzo Dominioni, Douglas M. Noonan, Lorenzo Mortara, Antonino Bruno

“…NK cells from pleural effusion of patients with inflammatory conditions (iPE, n = 18), primary tumor (ptPE, n = 18), and metastatic tumor (tmPE, n = 27) acquired the CD56brightCD16− phenotype. NK cells from both ptPE and tmPE showed increased expression for the CD49a and CD69 decidual-like (dNK) markers and decreased levels of the CD57 maturation marker. …”
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Efficacy of Tui Na in idiopathic constipation in children with cerebral palsy: a randomized controlled clinical trial by Huijuan Wang, Bichan Chen, Qian Long, Qiuping Yang, Jiawen Mao, Qinghua Ma, Xingqian Yi, Ying Wang, Yinghan Liu, Zhiliang Cao, Jianda Xu, Yong Ye, Wei Tang

“…Initially, the CAS score, weekly bowel movements and proportion of infants with bowel evacuation ≥2 h were comparable between the two groups (P &gt; 0.05). At 4 weeks after the final treatment, the CAS score, weekly bowel movements and proportion of infants with bowel evacuation ≥2 h all significantly improved (P &lt; 0.05) compared with those in the initial situation. …”
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Functional differentiation of human dental pulp stem cells into neuron-like cells exhibiting electrophysiological activity by B. Pardo-Rodríguez, A. M. Baraibar, I. Manero-Roig, J. Luzuriaga, J. Salvador-Moya, Y. Polo, R. Basanta-Torres, F. Unda, S. Mato, Gaskon Ibarretxe, Jose Ramon Pineda

“…Treatment with KCl and RA increased the amount of both voltage-gated Na+ and K+ channel subunits in neurodifferentiated hDPSCs at the transcript level. …”
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Blockchain dan Kecerdasan Buatan dalam Pertanian : Studi Literatur by Fajar Delli Wihartiko, Sri Nurdiati, Agus Buono, Edi Santosa

“…This paper summarizes the application of both technologies and reviews them in a systematic literature review, presents a description of articles based on text mining, and provides future research challenges related to the implementation of blockchain and artificial intelligence in agriculture. …”
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