Comprehensive profiling of serum microRNAs in normal and non-alcoholic fatty liver disease (NAFLD) patients by Jian-Wei Zhang, Kamran Ullah, Nauman Khan, Hai-Tao Pan

“…Targeting miR-122 may offer potential therapeutic benefits for improving both liver and heart health in individuals with NAFLD.…”
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Influence of sediment additions on the mechanical behavior of fiber-reinforced concrete in aggressive environments by Louafi Goudih, Hamid Sellaf, Benamar Balegh, Ali Meksi, Adda Hadj Mostefa, Mohamed Elamine Dahamni

“…Additionally, all concrete samples exhibited good resistance to sulfuric acid due to the formation of expansive ettringite which protected the concrete from further degradation. …”
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Towards a sustainable set of European Core Health Indicators (ECHI) by Mariken J. Tijhuis, Eveline A. van der Wilk, Sarka Dankova, Angela Fehr, Silvia Ghirini, Mika Gissler, Romana Haneef, Heidi Lyshol, Emanuele Scafato, Stefanie Seeling, Hanna Tolonen, Thomas Ziese, Irisa Zīle-Velika, Peter W. Achterberg

“…The ECHI set adds value to European Union health information systems (HIS) for both Member States and EU-associated countries and the European Commission by providing a solid, comparable information base on national public health and healthcare trends and developments. …”
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Snow depth estimation on leadless landfast ice using Cryo2Ice satellite observations by M. Saha, J. Stroeve, J. Stroeve, D. Isleifson, J. Yackel, V. Nandan, V. Nandan, J. C. Landy, H. M. Lam

“…Moreover, the proposed methodology for getting snow depth over leadless landfast sea ice needs to be validated using in situ datasets in other landfast sea ice regions in the Arctic.…”
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Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…Participants will complete audio-recorded speech tasks and both general and cohort-specific symptom scales. …”
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mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction by Seon-Yeong Lee, Jeonghyeon Moon, A Ram Lee, Young-Mee Moon, Jeong Won Choi, Chae Rim Lee, Su Been Jeon, Hee Su Sohn, Jeehee Youn, Dongyun Shin, Sung-Hwan Park, Mi-La Cho

“…We observed the accumulation of abnormal autophagosomes, increased inflammatory cell death signaling, and decreased mitoSTAT3 activity in FLSs from both patients with RA and patients with IL-17-treated FLSs. …”
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Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…Based on the obtained data and the appropriate mathematical models (Stern-Volmer and Klotz models), it can be concluded that 10-Pyr-3,6-DAPT probably forms a weak (K_a = (5.24 ± 0.57) <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>×</mo></mrow></semantics></math></inline-formula> 10⁴ and K_a = (4.67 ± 0.59) <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>×</mo></mrow></semantics></math></inline-formula> 10⁴) for excitation wavelengths λ_ex 275 nm and λ_ex 295 nm, respectively) static complex (k_q > 10¹⁰) with HSA (at Sudlow site II (subdomain IIIA), and the phenomenon of it having both strong therapeutic and toxic effects is possible. …”
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Physiological and image-based phenotyping assessment of waterlogging responses of three kiwifruit rootstocks and grafting combinations by Maria Calabritto, Alba N. Mininni, Roberto Di Biase, Angelo Petrozza, Stephan Summerer, Francesco Cellini, Bartolomeo Dichio

“…Leaf gas exchange, photosynthetic activity, leaf temperature, RGB, and NIR data were collected during waterlogging stress.ResultsStomatal conductance and transpiration reached very low values (less than 0.05 mol m−2 s−1 and 1 mmol m−2 s−1, respectively) in both waterlogged D and H rootstocks and their grafting combinations. …”
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Dynamic hydrogen-bonding enables high-performance and mechanically robust organic solar cells processed with non-halogenated solvent by Haozhe He, Xiaojun Li, Jingyuan Zhang, Zekun Chen, Yufei Gong, Hongmei Zhuo, Xiangxi Wu, Yuechen Li, Shijie Wang, Zhaozhao Bi, Bohao Song, Kangkang Zhou, Tongling Liang, Wei Ma, Guanghao Lu, Long Ye, Lei Meng, Ben Zhang, Yaowen Li, Yongfang Li

“…Abstract Developing active-layer systems with both high performance and mechanical robustness is a crucial step towards achieving future commercialization of flexible and stretchable organic solar cells (OSCs). …”
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Virtual Reality Simulation for Undergraduate Nursing Students for Care of Patients With Infectious Diseases: Mixed Methods Study by Wen Chang, Chun-Chih Lin, Julia Crilly, Hui-Ling Lee, Li-Chin Chen, Chin-Yen Han

“…ResultsA total of 107 students participated in phase 1, and 18 students participated in phase 2. Both the VRS and control groups showed significant improvements in theoretical knowledge scores (for the VRS group t46=–7.47; P<.001, for the control group t59=–4.04; P<.001). …”
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Association of neighborhood level socioeconomic status and patient reported clinical improvement following total shoulder arthroplasty by Caleb Morgan, MD, Amanda Firoved, MOT, OTR, Patrick J. Denard, MD, Justin W. Griffin, MD

“…Background: Prior studies have demonstrated higher preoperative pain and decreased patient-reported outcomes (PROs) following total shoulder arthroplasty (TSA) in individuals with lower socioeconomic status (SES). The goal of this study was to investigate the rate of clinical improvement following TSA in individuals with differing SES. …”
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Unlocking barriers and strategies of halal certification for micro and small enterprises in Indonesia: Analytic network process approach by Muhammad Anwar Fathoni, Prima Dwi Priyatno, Faizi, Fadhli Suko Wiryanto, Widarto Rachbini, Suryani

“…This analysis contributes to the broader discourse on enhancing MSE participation in the halal market, offering implications for both local and international stakeholders seeking to optimize the halal certification process. …”
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Phytolith assemblages from palm leaves and palm-leaf manuscripts: what is the difference and what it could mean? by Anastasia Poliakova, Anastasia Poliakova, Anastasia Poliakova, Giovanni Ciotti, Giovanni Ciotti, Giovanni Ciotti, Agnieszka Helman-Wazny, Agnieszka Helman-Wazny, Agnieszka Helman-Wazny, Agnieszka Helman-Wazny, Jörg Fromm, Jörg Fromm

“…Phytolith assemblages significantly differed between fresh, dry and herbarized palm leaves in comparison to PLM material, both qualitatively and quantitatively (mean r2 = - 0.61 ± 9.3 for Borassus samples and r2 = - 0.75 ± 5.3 for Corypha samples, at p &lt; 0.001). …”
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Characterizing immune biomarkers and effector CD8+ T-cell exhaustion in pancreatic adenocarcinoma via single-cell RNA sequencing profiling by Rawaa AlChalabi, Raghda Makia, Semaa A. Shaban, Ahmed AbdulJabbar Suleiman

“…Drug repurposing of oxaprozin and celecoxib showed favorable binding interactions with both wild and mutant IL7R proteins. Conclusions: The K110N mutation, despite not causing significant structural changes, may impact T-cell and B-cell homeostasis and development. …”
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Association between white blood cell count and coronary artery bypass graft failure: an individual patient data analysis of clinical trials by Kevin R. An, Sigrid Sandner, Joyce Peper, Yanzai Zhou, Jurrien M. ten Berg, Lamia Harik, Yunpeng Zhu, Laura M. Willemsen, Qiang Zhao, Björn Redfors, Subodh Verma, Mario F. L. Gaudino

“…There was no association between WBC count and graft failure at both the patient and the individual graft level [adjusted odds ratio (aOR) 1.07 (95% confidence interval (CI), 0.98;1.17), p = 0.11 and aOR 1.09 (95% CI, 0.91;1.30), p = 0.37], respectively. …”
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Molecular and biological characterization of infectious full-length cDNA clones of two viruses in Paris yunnanensis, including a novel potyvirus by Pingxiu Lan, Peng He, Aiqiu Mu, Mengji Cao, Yun Wang, Guohua Zhou, Xiaojiao Chen, Hong Cai, Fan Li

“…To characterize their biological features, two infectious clones, representing the two viruses, have been constructed through homologous recombination or yeast homologous recombination, and inoculated to several species plants, respectively. The results showed both of the viruses can infect P. yunnanensis and Nicotiana benthamiana. …”
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Effects of Sublingual Duster Mite Drops on Lung Function and Exhaled Nitric Oxide in Children with Multiple and Single Allergic Respiratory Diseases by Li Wang, Tao Ai, Ronghua Luo, Yinghong Fan, Huiling Liao, Wanmin Xia, Cheng Xie, Yaping Duan, Yanru Liu

“…The rhinitis score, VAS score, and drug score in the multiple allergic group after treatment were significantly lower than those before treatment (p<0.05), but there was no significant difference in the scores of daytime symptoms and nighttime symptoms before and after treatment (p>0.05). In both the single allergic group and multiple allergic group, the pulmonary function indexes of the patients were significantly improved after treatment, and the FeNO after treatment was significantly lower than that before treatment (p<0.05). …”
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Managing Water-Ecosystem-Food Nexus using participatory approaches: insights from an innovative methodological approach developed in two Mediterranean areas by Dimitrios Malamataris, Vassilios Pisinaras, Alessandro Pagano, Valentina Baratella, Silvia Vanino, Manuel Bea, Konstantinos Babakos, Anna Chatzi, Stefano Fabiani, Raffaele Giordano, Petros Kafkias, Estrella López-Moya, Christina Papadaskalopoulou, Ivan Portoghese, Dimitris Tassopoulos, Andreas Panagopoulos

“…The formulation of effective policies to address both the present allocation and future conservation of natural resources in an integrated way remains an essential and challenging task. …”
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Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

“…The synergistic and opposed effects of the two systems on virulence and antibiotic-resistance genes need further study.IMPORTANCEK. pneumoniae is an important opportunistic pathogen responsible for both human and animal infections, and the emergence of hypervirulent and multidrug-resistant K. pneumoniae has made it difficult to control this pathogen worldwide. …”
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Spatiotemporal evolution of landscape ecological risk and its driving factors of the Beijing–Tianjin–Hebei major mineral belt, 1985–2022 by Yilin Wang, Xiaohong Wang, Wei Zhang, Weidong Man, Mingyue Liu, Linlin Jiao

“…The pattern of landscape ecological risk exhibits both ‘high-high’ aggregation and ‘low-low’ aggregation. …”
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