Porphyromonas gingivalis associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population by Helga Westerlind, Linda Mathsson-Alm, Alexandra Circiumaru, Aase Hensvold, Karin Lundberg, Jan Potempa, Yogan Kisten, Charlotte De Vries, Marina Dehara, Barbara Potempa

“…The anti-Rgp IgG response at baseline did not associate with the development of arthritis; Cox-regression showed an HR of 0.95 (CI 0.80 to 1.13, p=0.6) for anti-Rgp IgG levels, and 0.82 (CI 0.55 to 1.23, p=0.3) for anti-Rgp IgG positivity.Conclusions Antibodies against the oral bacterium Pg are elevated during the RA-risk phase, both in individuals progressing to arthritis and in individuals remaining arthritis-free. …”
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Impact of Sjögren’s disease on quality of sexual life using the Qualisex score by Eric Hachulla, Xavier Mariette, Jacques-Eric Gottenberg, Philippe Dieude, Aleth Perdriger, Emanuelle Dernis, Marion Couderc, Raphaele Seror, Gaetane Nocturne, Rakiba Belkhir, Valérie Devauchelle-Pensec, Veronique Le Guern, Alexandra Kachaner, Sophie Berville

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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

“…Using live cell imaging of rickA::Tn and sca2::Tn mutants, we discovered both RickA and Sca2 contribute to different modes of cell-to-cell spread. …”
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Silver Trimolybdate (Ag2Mo3O10.2H2O) Nanorods: Synthesis, Characterization, and Photo-Induced Antibacterial Activity under Visible-Light Irradiation by Maria Karollyna do Nascimento Silva Leandro, João Victor Barbosa Moura, Ana Carolina Justino de Araújo, Priscilla Ramos Freitas, Cicera Laura Roque Paulo, Amanda Karine de Sousa, Janaina Esmeraldo Rocha, Lívia Maria Garcia Leandro, Rakel Olinda Macedo da Silva, Clenilton Costa dos Santos, Jaime Ribeiro-Filho, Cleânio da Luz Lima, Abolghasem Siyadatpanah, Zahra Seifi, Bonglee Kim, Henrique Douglas Melo Coutinho

“…The treatment with Ag2Mo3O10.2H2O nanorods alone or combined with visible LED lights exhibited clinically relevant antibacterial activity against both Gram-negative and Gram-positive bacteria. This nanostructure presented a variable antibiotic-modulating action, which was not improved by visible LED light exposure. …”
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The role of paternal support in breastfeeding outcomes: a meta-analytic review by Si-si Zhou, Jia Lu, An Qin, Yang Wang, Wei Gao, Hong Li, Lin Rao

“…Conclusions The findings suggest that current evidence supports the efficacy of paternal support interventions in both the initiation and maintenance of breastfeeding.…”
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Ascorbate-glutathione cycle in wheat and rice seedlings under anoxia and subsequent reaeration by V. V. Yemelyanov, E. G. Prikaziuk, V. V. Lastochkin, O. M. Aresheva, T. V. Chirkova

“…In the resistant plant (rice), reduced forms of these antioxidants prevailed both in normoxia and under stress, which may indicate their intensive reduction. …”
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Neutrophil-to-lymphocyte, platelet-to-lymphocyte ratios and systemic immune-inflammation index in patients with post-traumatic stress disorder by Gözde Yontar, Elif Aktan Mutlu

“…Neutrophil and platelet levels of PTSD patients were significantly higher than controls although both groups’ values were in normal range. Moreover, NLR, PLR and SII were significantly higher in PTSD group. …”
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Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

“…The M6P-conjugated antibody against a protein of interest (POI) efficiently internalized targeted soluble proteins, such as human tumor necrosis factor (TNF), in both cancer cell lines and human immune cells, through the endo-lysosomal pathway as demonstrated by confocal microscopy and flow cytometry. …”
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Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli by Jacquelyn Blake-Hedges, Dan Groff, Wilson Foo, Jeffrey Hanson, Elenor Castillo, Miao Wen, Diana Cheung, Mary Rose Masikat, Jian Lu, Young Park, Nina Abi Carlos, Hans Usman, Kevin Fong, Abigail Yu, Sihong Zhou, Joyce Kwong, Cuong Tran, Xiaofan Li, Dawei Yuan, Trevor Hallam, Gang Yin

“…Using high-density fermentation, it was possible to produce both of these types of molecules with site-specifically incorporated nnAAs at titers > 1 g/L. …”
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Association of extreme heat events with sleep and cardiovascular health: a scoping review by Nathan Ashe, Sarah Wozniak, Malcolm Conner, Rayan Ahmed, Olivia Keenan, Michelle R. Demetres, Nour Makarem, Parisa Tehranifar, Rajalakshmi Nandakumar, Arnab K. Ghosh

“…During EHEs, individuals slept for shorter periods of time and less efficiently, with greater degrees of HR variability in two of the three studies lasting at most 1–2 days; BP (both systolic and diastolic) significantly decreased during EHEs in two of the studies. …”
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Comprehensive analysis of peripheral dose in electron beam therapy with a Varian TrueBeam Linac by Kapil Dev Maharaj, Mahsheed Sabet, Joshua Dass, Mounir Ibrahim, Talat Mahmood, Pejman Rowshanfarzad

“…Conclusions: This study highlights the importance of considering peripheral doses in electron radiotherapy. It is important to note the impact on healthy tissues beyond the treatment area to ensure patient safety and prevent the long-term side effects of treatment. …”
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Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis by Patrick Mukadi-Kakoni, Yannick Munyeku-Bazitama, Gracia Kashitu-Mujinga, Marguerite Manwana-Pemba, Niclette Zenga-Bibi, Patient Okitale-Talunda, Christelle Mbelu-Kabongo, Fleurette Domai-Mbuyakala, Elisabeth Pukuta-Simbu, Pierre Mutantu-Nsele, Yoshinao Kubo, Sheila Makiala-Mandanda, Steve Ahuka-Mundeke, Koya Ariyoshi, Jean-Jacques Muyembe-Tamfum

“…Acute HBV infection was defined by both HBc IgM and HBs antigen positivity. Multivariable logistic regression was used to assess the association of demographic, geographic, and environmental factors with each hepatitis type. …”
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Oxidation Behavior of Matrix Graphite and Its Effect on Compressive Strength by Xiangwen Zhou, Cristian I. Contescu, Xi Zhao, Zhenming Lu, Jie Zhang, Yutai Katoh, Yanli Wang, Bing Liu, Yaping Tang, Chunhe Tang

“…Microstructure images of SEM and porosity measurement by Mercury Porosimetry indicate that the significant compressive strength loss of MG oxidized at 550°C may be attributed to both the uniform pore formation throughout the bulk and the preferential oxidation of the binder.…”
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A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice by Cristina Méndez-Vidal, Nereida Bravo-Gil, Javier Pérez-Florido, Irene Marcos-Luque, Raquel M. Fernández, José Luis Fernández-Rueda, María González-del Pozo, Marta Martín-Sánchez, Elena Fernández-Suárez, Marcela Mena, Rosario Carmona, Joaquín Dopazo, Salud Borrego, Guillermo Antiñolo

“…Abstract Background Despite the use of Next-Generation Sequencing (NGS) as the gold standard for the diagnosis of rare diseases, its clinical implementation has been challenging, limiting the cost-effectiveness of NGS and the understanding, control and safety essential for decision-making in clinical applications. …”
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Dissemination of Staphylococcus epidermidis in Swedish bovine dairy herds: minimal overlap with human isolates by Karin Persson Waller, Mattias Myrenås, Hyeyoung Kim, Micael Widerström, Tor Monsen, Stefan Börjesson, Stefan Börjesson, Stefan Börjesson, Emma Östlund, Wonhee Cha

“…Only four STs (ST59, ST73, ST184, and ST218), representing a total of 13 isolates, were found in both bovine and human samples. Genes conferring AMR were more frequently identified in human patient isolates compared to bovine isolates. …”
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Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension by Chuchen Meng, Min Sun, Zhixiao Wang, Qi Fu, Mengdie Cao, Zhenxin Zhu, Jia Mao, Yun Shi, Wei Tang, Xiaoping Huang, Yu Duan, Tao Yang

“…BaPWV significantly decreased (P=0.032) with an increase in insulin sensitivity in individuals with both normal BP and glucose tolerance. Conclusions. …”
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Brain connectivity for constructing new face representations in typical adults versus a prosopagnosic patient by Ela I. Olivares, Jorge F. Bosch-Bayard, Ana S. Urraca, Alba Jiménez-Bascuñán, Rolando J. Biscay, Jaime Iglesias

“…Will our brains get to know a new face better if we look at its external features first? …”
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Power-free plasma separation based on negative magnetophoresis for rapid biochemical analysis by Lin Zeng, Chao Liu, Yi Yang, Shi Hu, Ruihan Li, Xiaotian Tan, Jienan Shen, Yi Zhang, Shaohui Huang, Hui Yang

“…The device demonstrates a separation efficiency of 99.9% for cells larger than 1 μm in both rat and human blood samples, with a plasma recovery rate of 72.7%. …”
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Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1 by Hong Zhou, Jiaxin Zhou, ShanShan Liu, Jing Niu, Jinghua Pan, Ruiman Li

“…Hsa-miR-532-3p is closely related to gestational age and has good predictive value for identifying RSA.…”
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Assessment of Hemoglobin Variants in Patients Receiving Health Care at the Ho Teaching Hospital: A Three-Year Retrospective Study by Daniel Kpodji Awaitey, Elliot Elikplim Akorsu, Emmanuel Allote Allotey, David Annor Kwasie, Precious Kwablah Kwadzokpui, Philip Apraku Tawiah, Stephen Adomako Amankwah, Albert Abaka-Yawson

“…Difference in the severity of anemia was found to be significant among both male (P=0.006) and female (P=0.004) participants with SCD. …”
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